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Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.unicef.org\/vietnam\/resources_12176.html\" xlink:type=\"simple\">http:\/\/www.unicef.org\/vietnam\/resources_12176.html<\/ext-link>."},{"key":"ref28","unstructured":"Centers for Disease Control and Prevention. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.cdc.gov\" xlink:type=\"simple\">http:\/\/www.cdc.gov<\/ext-link>. 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