{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:46:22Z","timestamp":1791236782371,"version":"4.1.0"},"reference-count":62,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2014,9,18]],"date-time":"2014-09-18T00:00:00Z","timestamp":1410998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0003167","type":"journal-article","created":{"date-parts":[[2014,9,18]],"date-time":"2014-09-18T14:05:04Z","timestamp":1411049104000},"page":"e3167","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":54,"title":["Genetic Diversity of Brazilian Aedes aegypti: Patterns following an Eradication Program"],"prefix":"10.1371","volume":"8","author":[{"given":"Fernando A.","family":"Monteiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Shama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ademir J.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gloria-Soria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia E.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Powell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,9,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/S0966-842X(01)02288-0","article-title":"Epidemic dengue\/dengue hemorrhagic fever as a public health, social and economic problem in the 21st century","volume":"10","author":"DJ Gubler","year":"2002","journal-title":"TRENDS in Microbiology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"743","DOI":"10.4269\/ajtmh.2012.12-0157","article-title":"The economic burden of dengue","volume":"86","author":"DJ Gubler","year":"2012","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1038\/nrmicro2460","article-title":"Dengue: a continuing global threat","volume":"8","author":"MG Guzman","year":"2010","journal-title":"Nature reviews Microbiology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/nature12060","article-title":"The global distribution and burden of dengue","volume":"496","author":"S Bhatt","year":"2013","journal-title":"Nature"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1146\/annurev.ento.53.103106.093326","article-title":"Dengue virus-mosquito interactions","volume":"53","author":"SB Halstead","year":"2008","journal-title":"Annual review of entomology"},{"key":"ref6","unstructured":"WHO (2012) Global Strategy for dengue prevention and control 2010\u20132012. World Health Organization. Geneva."},{"key":"ref7","doi-asserted-by":"crossref","first-page":"584","DOI":"10.4269\/ajtmh.2012.11-0770","article-title":"The history of dengue outbreaks in the Americas","volume":"87","author":"O Brathwaite Dick","year":"2012","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Consoli R, Louren\u00e7o-de-Oliveira R (1994) Principais mosquitos de import\u00e2ncia sanit\u00e1ria no Brasil. Rio de Janeiro, Brazil: Ed. Fiocruz. 228 p.","DOI":"10.7476\/9788575412909"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1590\/S0074-02762012000600021","article-title":"Why do wee need alternative tools to control mosquito-borne diseases in Latin America?","volume":"107","author":"R Maciel-de-Freitas","year":"2012","journal-title":"Mem\u00f3rias do Insituto Oswaldo Cruz"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1590\/S1020-49891997000100023","article-title":"The feasibility of eradicating <italic>Aedes agypti<\/italic> in the Americas","volume":"1","year":"1997","journal-title":"Revista Panamericana de Salud P\u00fablica"},{"key":"ref11","first-page":"277","article-title":"<italic>Aedes aegypti<\/italic>: inseticidas, mecanismos de a\u00e7\u00e3o e resist\u00eancia","volume":"16","author":"IA Braga","year":"2007","journal-title":"Epidemiol Serv Sa\u00fade"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1002\/ps.1406","article-title":"Insecticide resistance in disease vectors of public health importance","volume":"63","author":"R Nauen","year":"2007","journal-title":"Pest management science"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1590\/S0074-02762005000400017","article-title":"Monitoring of resistance to the pyrethroid cypermethrin in Brazilian <italic>Aedes aegypti<\/italic> (Diptera: Culicidae) populations collected between 2001 and 2003","volume":"100","author":"MP da-Cunha","year":"2005","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1146\/annurev.ento.51.110104.151104","article-title":"Molecular mechanisms of metabolic resistance to synthetic and natural xenobiotics","volume":"52","author":"X Li","year":"2007","journal-title":"Annual review of entomology"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"467","DOI":"10.4269\/ajtmh.2007.77.467","article-title":"Insecticide resistance mechanisms of Brazilian <italic>Aedes aegypti<\/italic> populations from 2001 to 2004","volume":"77","author":"IR Montella","year":"2007","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"108","DOI":"10.4269\/ajtmh.2009.81.108","article-title":"Voltage-gated sodium channel polymorphism and metabolic resistance in pyrethroid-resistant <italic>Aedes aegypti<\/italic> from Brazil","volume":"81","author":"AJ Martins","year":"2009","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1002\/ps.2189","article-title":"Gene amplification and insecticide resistance","volume":"67","author":"C Bass","year":"2011","journal-title":"Pest management science"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1756-3305-7-25","article-title":"Distribution and dissemination of the Val1016Ile and Phe1534Cys Kdr mutations in <italic>Aedes aegypti<\/italic> Brazilian natural populations","volume":"7","author":"JG Linss","year":"2014","journal-title":"Parasites & Vectors"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/nrmicro2968","article-title":"Beyond insecticides: new thinking on an ancient problem","volume":"11","author":"EA McGraw","year":"2013","journal-title":"Nature reviews Microbiology"},{"key":"ref20","first-page":"113","article-title":"<italic>Aedes aegypti<\/italic>: Hist\u00f3rico de Controle no Brasil","volume":"16","author":"IA Braga","year":"2007","journal-title":"Epidemiol Serv Sa\u00fade"},{"key":"ref21","first-page":"1","article-title":"<italic>Aedes aegypti<\/italic>, Dengue and Re-urbanization of Yellow Fever in Brazil and other South American Countries - Past and Present Situation and Future Perspectives","volume":"23","author":"PFC Vasconcelos","year":"1999","journal-title":"Dengue Bulletin"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1603\/0022-2585-40.4.430","article-title":"Genetic Differentiation of <italic>Aedes aegypti<\/italic> (Diptera: Culicidae), the Major Dengue Vector in Brazil","volume":"40","author":"CFJ Ayres","year":"2003","journal-title":"Journal of Medical Entomology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1590\/S1415-47572006000200030","article-title":"Genetic variability in geographical populations of <italic>Aedes aegypti<\/italic> (Diptera, Culicidae) in Brazil elucidated by molecular markers","volume":"29","author":"KS Paduan","year":"2006","journal-title":"Genetics and Molecular Biology"},{"key":"ref24","first-page":"350","article-title":"Genetic Structure of Natural Populations of <italic>Aedes aegypti<\/italic> at the Micro and Macrogeographic Levels in Brazil","volume":"20","author":"CFJ Ayres","year":"2004","journal-title":"Journal of the American Mosquito Control Association"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"303","DOI":"10.4269\/ajtmh.2007.77.303","article-title":"Low Gene Flow of <italic>Aedes aegypti<\/italic> between Dengue-Endemic and Dengue-Free Areas in Southeastern and Southern Brazil","volume":"77","author":"MCV Costa-Ribeiro","year":"2007","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1111\/j.1365-3156.2006.01667.x","article-title":"Geographic and temporal genetic patterns of <italic>Aedes aegypti<\/italic> populations in Rio de Janeiro, Brazil","volume":"11","author":"MCV Costa-Ribeiro","year":"2006","journal-title":"Tropical medicine & international health : TM & IH"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1590\/S0074-02762006000800015","article-title":"Higher genetic variation estimated by microsatellites compared to isoenzyme markers in <italic>Aedes aegypti<\/italic> from Rio de Janeiro","volume":"101","author":"MCV Costa-Ribeiro","year":"2006","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1590\/S0074-02762007005000062","article-title":"Genetic variability of <italic>Aedes aegypti<\/italic> in the Americas using a mitochondrial gene: evidence of multiple introductions","volume":"102","author":"JE Bracco","year":"2007","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"895","DOI":"10.4269\/ajtmh.2008.78.895","article-title":"Population Genetics and Phylogeography of <italic>Aedes aegypti<\/italic> (Diptera: Culicidae) from Brazil","volume":"78","author":"VM Scarpassa","year":"2008","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1098\/rspb.2010.2469","article-title":"Worldwide patterns of genetic differentiation imply multiple \u2018domestications\u2019 of <italic>Aedes aegypti<\/italic>, a major vector of human diseases","volume":"278","author":"JE Brown","year":"2011","journal-title":"Proceedings Biological sciences\/The Royal Society"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1111\/j.1471-8286.2006.01533.x","article-title":"Polymorphic microsatellite markers for studies of <italic>Aedes aegypti<\/italic> (Diptera: Culicidae), the vector of dengue and yellow fever","volume":"7","author":"MA Slotman","year":"2007","journal-title":"Molecular Ecology Notes"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/oxfordjournals.jhered.a111573","article-title":"GENEPOP (version 1.2): population genetics software for exact tests and ecumenicism","volume":"86","author":"M Raymond","year":"1995","journal-title":"Journal of Heredity"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1471-8286.2007.01931.x","article-title":"Genepop&apos;007: a complete reimplementation of the Genepop software for Windows and Linux","volume":"8","author":"F Rousset","year":"2008","journal-title":"Molecular ecology resources"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1111\/j.1471-8286.2004.00684.x","article-title":"Micro-checker: software for identifying and correcting genotyping errors in microsatellite data","volume":"4","author":"C Van Oosterhout","year":"2004","journal-title":"Molecular Ecology Notes"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1093\/molbev\/msl191","article-title":"Microsatellite null alleles and estimation of population differentiation","volume":"24","author":"MP Chapuis","year":"2007","journal-title":"Molecular biology and evolution"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"2537","DOI":"10.1093\/bioinformatics\/bts460","article-title":"GenAlEx 6.5: genetic analysis in Excel. Population genetic software for teaching and research\u2013an update","volume":"28","author":"R Peakall","year":"2012","journal-title":"Bioinformatics"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1023\/B:COGE.0000041021.91777.1a","article-title":"Counting alleles with rarefaction: private alleles and hierarchical sampling designs","volume":"5","author":"ST Kalinowski","year":"2004","journal-title":"Conservation Genetics Resources"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1471-8286.2004.00845.x","article-title":"Hp-rare 1.0: a computer program for performing rarefaction on measures of allelic richness","volume":"5","author":"ST Kalinowski","year":"2005","journal-title":"Molecular Ecology Notes"},{"key":"ref39","first-page":"47","article-title":"Arlequin (version 3.0): An integrated software package for population genetics data analysis","volume":"1","author":"L Excoffier","year":"2005","journal-title":"Evolutionary Bioinformatics Online"},{"key":"ref40","unstructured":"Felsenstein J (2005) PHYLIP (Phylogeny Inference Package) version 3.6. Department of Genome Sciences, University of Washington, Seattle."},{"key":"ref41","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1111\/j.1365-294X.2008.03869.x","article-title":"Do outbreaks affect genetic population structure? A worldwide survey in <italic>Locusta migratoria<\/italic>, a pest plagued by microsatellite null alleles","volume":"17","author":"MP Chapuis","year":"2008","journal-title":"Molecular ecology"},{"key":"ref42","unstructured":"Belkhir K, Borsa P, Chikhi L, Raufaste N, Bonhomme F (1996\u20132004) GENETIX 4.05, logiciel sous Windows TM pour la g\u00e9n\u00e9tique des populations. Laboratoire G\u00e9nome, Populations, Interactions, CNRS UMR 5000: Universit\u00e9 de Montpellier II, Montpellier, France."},{"key":"ref43","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/1471-2156-6-13","article-title":"Isolation by distance, web service","volume":"6","author":"JL Jensen","year":"2005","journal-title":"BMC Genet"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/genetics\/155.2.945","article-title":"Inference of Population Structure Using Multilocus Genotype Data","volume":"155","author":"JK Pritchard","year":"2000","journal-title":"Genetics"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s12686-011-9548-7","article-title":"STRUCTURE HARVESTER: a website and program for visualizing STRUCTURE output and implementing the Evanno method","volume":"4","author":"DA Earl","year":"2012","journal-title":"Conservation Genetics Resources"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1111\/j.1365-294X.2005.02553.x","article-title":"Detecting the number of clusters of individuals using the software STRUCTURE: a simulation study","volume":"14","author":"G Evanno","year":"2005","journal-title":"Molecular ecology"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1093\/bioinformatics\/btm233","article-title":"CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure","volume":"23","author":"M Jakobsson","year":"2007","journal-title":"Bioinformatics"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1046\/j.1471-8286.2003.00566.x","article-title":"Distruct: a program for the graphical display of population structure","volume":"4","author":"NA Rosenberg","year":"2004","journal-title":"Molecular Ecology Notes"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1093\/jhered\/esh074","article-title":"GENECLASS2: a software for genetic assignment and first-generation migrant detection","volume":"95","author":"S Piry","year":"2004","journal-title":"The Journal of heredity"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1017\/S0007485310000490","article-title":"Multiple origins of outbreak populations of a native insect pest in an agro-ecosystem","volume":"101","author":"T Kobayashi","year":"2011","journal-title":"Bull Entomol Res"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"4412","DOI":"10.3390\/ijms13044412","article-title":"Isolation and characterization of twelve polymorphic microsatellite Loci for the cocoa mirid bug <italic>Sahlbergella singularis<\/italic>","volume":"13","author":"R Babin","year":"2012","journal-title":"International journal of molecular sciences"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.ijpara.2013.12.001","article-title":"Microsatellite and mitochondrial markers reveal strong gene flow barriers for <italic>Anopheles farauti<\/italic> in the Solomon Archipelago: implications for malaria vector control","volume":"44","author":"L Ambrose","year":"2014","journal-title":"International journal for parasitology"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1093\/genetics\/139.1.457","article-title":"A measure of population subdivision based on microsatellite allele frequencies","volume":"139","author":"M Slatkin","year":"1995","journal-title":"Genetics"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1093\/jhered\/esn048","article-title":"Effects of microsatellite null alleles on assignment testing","volume":"99","author":"J Carlsson","year":"2008","journal-title":"The Journal of heredity"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.1002\/ece3.392","article-title":"Seasonal population dynamics and the genetic structure of the mosquito vector <italic>Aedes aegypti<\/italic> in Sao Paulo, Brazil","volume":"2","author":"M Campos","year":"2012","journal-title":"Ecology and evolution"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0035-9203(03)00006-3","article-title":"<italic>Aedes aegypti<\/italic> in Brazil: genetically differentiated populations with high susceptibility to dengue and yellow fever viruses","volume":"98","author":"R Louren\u00e7o-de-Oliveira","year":"2004","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3201\/eid1404.071185","article-title":"Dengue Virus Type 4, Manaus, Brazil","volume":"14","author":"RMP Figueiredo","year":"2008","journal-title":"Emerging Infectious Diseases"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1590\/S0074-02762009000400014","article-title":"Seasonal dynamics of <italic>Aedes aegypti<\/italic> (Diptera: Culicidae) in the northernmost state of Brazil: a likely port-of-entry for dengue virus 4","volume":"104","author":"CT Code\u00e7o","year":"2009","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1111\/j.1752-4571.2012.00244.x","article-title":"Gene flow networks among American Aedes aegypti populations","volume":"5","author":"A Goncalves da Silva","year":"2012","journal-title":"Evolutionary applications"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"479","DOI":"10.4269\/ajtmh.2008.78.479","article-title":"Genetic Relationships among <italic>Aedes aegypti<\/italic> Collections in Venezuela as Determined by Mitochondrial DNA Variation and Nuclear Single Nucleotide Polymorphisms","volume":"78","author":"L Urdaneta-Marquez","year":"2008","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/jmedent\/45.1.59","article-title":"Mitochondrial DNA Polymorphism and Heteroplasmy in Populations of <italic>Aedes aegypti<\/italic> in Brazil","volume":"45","author":"KS Paduan","year":"2008","journal-title":"Journal of Medical Entomology"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/evo.12281","article-title":"Human impacts have shaped historical and recent evolution in <italic>Aedes aegypti<\/italic>, the dengue and yellow fever mosquito","volume":"68","author":"JE Brown","year":"2014","journal-title":"Evolution; international journal of organic evolution"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0003460","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T00:00:00Z","timestamp":1418947200000}}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0003167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,17]],"date-time":"2022-04-17T06:29:48Z","timestamp":1650176988000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0003167"}},"subtitle":[],"editor":[{"given":"Enock","family":"Matovu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,9,18]]},"references-count":62,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2014,9,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0003167","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,18]]}}}