{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T06:03:09Z","timestamp":1785564189103,"version":"3.56.0"},"reference-count":51,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T00:00:00Z","timestamp":1411603200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0003184","type":"journal-article","created":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T19:21:52Z","timestamp":1411672912000},"page":"e3184","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Evaluation of Biochemical, Hematological and Parasitological Parameters of Protein-Deficient Hamsters Infected with Ancylostoma ceylanicum"],"prefix":"10.1371","volume":"8","author":[{"given":"Carina P.","family":"Pacanaro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00edlvia R.","family":"Dias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana R.","family":"Serafim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana P.","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edenil","family":"Aguilar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo R.","family":"Paes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline I.","family":"Alvarez-Leite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9lida M.","family":"Rabelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,9,25]]},"reference":[{"issue":"Suppl","key":"ref1","first-page":"S158","article-title":"Molecular pathogenesis of hookworm anemia: prospects for a disease-based vaccine","volume":"89","author":"M Cappello","year":"2003","journal-title":"J Parasitol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1093\/4.4.830","article-title":"Hookworm disease: nutritional implications","volume":"4","author":"EP Variyam","year":"1982","journal-title":"Rev Infect Dis"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/ajcn\/65.1.153","article-title":"Epidemiology of iron deficiency anemia in Zanzibari schoolchildren: the importance of hookworms","volume":"65","author":"RJ Stoltzfus","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/j.1753-4887.1997.tb01609.x","article-title":"Hookworm control as a strategy to prevent iron deficiency","volume":"55","author":"RJ Stoltzfus","year":"1997","journal-title":"Nutr Rev"},{"issue":"Suppl","key":"ref5","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1017\/S0031182000006491","article-title":"Malnutrition and parasitic helminth infections","volume":"121","author":"LS Stephenson","year":"2000","journal-title":"Parasitology"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1146\/annurev.nutr.22.120501.134539","article-title":"Nutritional impact of intestinal helminthiasis during the human life cycle","volume":"22","author":"DWT Crompton","year":"2002","journal-title":"Annu Rev Nutr"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1093\/jn\/130.10.2527","article-title":"Hookworms, Malaria and Vitamin A Deficiency Contribute to Anemia and Iron Deficiency among Pregnant Womam in the Plains of Nepal","volume":"130","author":"ML Dreyfuss","year":"2000","journal-title":"J Nutr"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1079\/PNS19930042","article-title":"The impact of gastrointestinal parasites on protein-energy malnutrition in man","volume":"52","author":"PG Lunn","year":"1993","journal-title":"Proc Nutr Soc"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S0020-7519(96)80070-1","article-title":"Nutrition and parasite interaction","volume":"26","author":"RL Coop","year":"1996","journal-title":"Int J Parasitol"},{"key":"ref10","article-title":"Food and Agriculture Organization of the United Nations. The state of food insecurity in the world 2006: eradicating world hunger \u2014 taking stock ten years after the World Food Summit","year":"2006"},{"key":"ref11","unstructured":"World Health Organization. Levels &amp; Trends in Child Mortality Report 2013 Estimates Developed by the UN Inter-agency Group for Child Mortality Estimation Available from:<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/maternal_child_adolescent\/documents\/levels_trends_child_mortality_2013.pdf?ua=1\" xlink:type=\"simple\">http:\/\/www.who.int\/maternal_child_adolescent\/documents\/levels_trends_child_mortality_2013.pdf?ua=1<\/ext-link>"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1136\/bmj.291.6495.587","article-title":"ABC of nutrition. Malnutrition in the Third World-II","volume":"291","author":"AS Truswell","year":"1985","journal-title":"Br Med J (Clin Res Ed)"},{"key":"ref13","first-page":"649","article-title":"Nutritional disturbances of protein metabolism in the liver","volume":"84","author":"H Sidransky","year":"1976","journal-title":"Am J Pathol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1046\/j.1365-3016.2002.00402.x","article-title":"Malnutrition and susceptibility to enteroparasites: reinfection rates after mass chemotherapy","volume":"16","author":"SRM Saldiva","year":"2002","journal-title":"Paediatr Perinat Epidemiol"},{"key":"ref15","first-page":"227","article-title":"Nutritional aspects of parasitic infection","volume":"9","author":"A Hall","year":"1985","journal-title":"Prog Food Nutr Sci"},{"issue":"Suppl","key":"ref16","doi-asserted-by":"crossref","first-page":"S125","DOI":"10.1017\/S0031182000075557","article-title":"Ascariasis and childhood malnutrition","volume":"107","author":"T Hlaing","year":"1993","journal-title":"Parasitology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"S19","DOI":"10.1017\/S003118200007548X","article-title":"Pathways to the impairment of human nutritional status by gastrointestinal pathogens","volume":"107","author":"NW Solomons","year":"1993","journal-title":"Parasitology"},{"key":"ref18","first-page":"169","article-title":"Helminth parasites, a major factor in malnutrition","volume":"15","author":"LS Stephenson","year":"1994","journal-title":"World Health Forum"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"464S","DOI":"10.1093\/ajcn\/66.2.464S","article-title":"Synergism of nutrition, infection, and immunity: an overview","volume":"66","author":"NS Scrimshaw","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1079\/BJN19590038","article-title":"Malnutrition in African adults. 5. Effects of hookworm infestation on absorption of foodstuffs","volume":"13","author":"SJ Darke","year":"1959","journal-title":"Br J Nutr"},{"key":"ref21","first-page":"108","article-title":"Hookworm anaemia and intestinal malabsorption associated with hookworm infestation","volume":"19","author":"AK Saraya","year":"1975","journal-title":"Prog Drug Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1056\/NEJMra032492","article-title":"Current concepts: hookworm infection","volume":"351","author":"PJ Hotez","year":"2004","journal-title":"N Engl J Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/S0140-6736(06)68653-4","article-title":"Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm","volume":"367","author":"J Bethony","year":"2006","journal-title":"Lancet"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/cid\/ciu211","article-title":"Childhood malnutrition and parasitic helminth interactions","volume":"59","author":"K Papier","year":"2014","journal-title":"Clin Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1365-3024.2005.00770.x","article-title":"Effect of a low protein diet on the resistance of Churra sheep to <italic>Teladorsagia circumcincta<\/italic>","volume":"27","author":"M Mart\u00ednez-Valladares","year":"2005","journal-title":"Parasite Immunol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0031-9384(99)00043-8","article-title":"Operant responding for dietary protein in the golden hamster (<italic>Mesocricetus auratus<\/italic>)","volume":"67","author":"D DiBattista","year":"1999","journal-title":"Physiol Behav"},{"key":"ref27","first-page":"50","article-title":"A new technique for counting nematode eggs in sheep feaces","volume":"12","author":"HM Gordon","year":"1939","journal-title":"J Counc Sci Ind Res"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1002\/ar.1091390309","article-title":"The orbital region as a source of blood samples inthe golden hamster","volume":"139","author":"B Pansky","year":"1961","journal-title":"Anatomical Record"},{"key":"ref29","unstructured":"Gad SC, Hess FG (2007) The hamster. In: Gad SC, editor. Animal models in toxicology. 2<sup>a<\/sup> ed. EUA: CRC Press. pp. 297."},{"key":"ref30","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipids from animal tissues","volume":"226","author":"J Folch","year":"1957","journal-title":"J Biol Chem"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1086\/587658","article-title":"The interaction between nutrition and infection","volume":"46","author":"P Katona","year":"2008","journal-title":"Clin Infect Dis"},{"key":"ref32","unstructured":"Emmans GC, Kyriazakis I (2000) Issues arising from genetic selection for growth and body composition charascteristics in poultry and pigs. In: Hill WG, Bishop SC, Mcguirk B, McKay JC, Simm G, Webb AJ, editors. The Challenge Of Genetic Change In: Animal Production. British Society of Animal Science, Penicuik, pp. 39\u201353"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1017\/S0031182011000990","article-title":"Interactive effects of protein nutrition, genetic growth potential and <italic>Heligmosomoides bakeri<\/italic> infection pressure on resilience and resistance in mice","volume":"138","author":"JC Coltherd","year":"2011","journal-title":"Parasitology"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"3378","DOI":"10.1210\/jcem.87.7.8699","article-title":"Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patients","volume":"87","author":"G Biolo","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1017\/S0031182099006526","article-title":"The use of a gamma-type function to assess the relationship between the number of adult <italic>Teladorsagia circumcincta<\/italic> and total egg output","volume":"121","author":"SC Bishop","year":"2000","journal-title":"Parasitology"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1016\/j.ijpara.2007.04.023","article-title":"Density-dependent immune responses against the gastrointestinal nematode <italic>Strongyloides ratti<\/italic>","volume":"37","author":"C Bleay","year":"2007","journal-title":"Int J Parasitol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1079\/BJN2001468","article-title":"The effects of condensed tannins supplementation of foods with different protein content on parasitism, food intake and performance of sheep infected with <italic>Trichostrongylus colubriformis<\/italic>","volume":"86","author":"S Athanasiadou","year":"2001","journal-title":"Br J Nutr"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1017\/S0031182009006428","article-title":"Genetic growth potential interacts with nutrition on the ability of mice to cope with <italic>Heligmosomoides bakeri<\/italic> infection","volume":"136","author":"JC Coltherd","year":"2009","journal-title":"Parasitology"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1111\/j.1365-3024.2005.00770.x","article-title":"Effect of a low protein diet on the resistance of Churra sheep to <italic>Teladorsagia circumcincta<\/italic>","volume":"27","author":"M Mart\u00ednez-Valladares","year":"2005","journal-title":"Parasite Immunol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-3024.2008.01069.x","article-title":"Protein-energy malnutrition decreases immune response to <italic>Leishmania chagasi<\/italic> in BALB\/c mice","volume":"31","author":"G Malafaia","year":"2009","journal-title":"Parasite Immunol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1189\/jlb.71.1.16","article-title":"Nutrients and their role in host resistance to infection","volume":"71","author":"CJ Field","year":"2002","journal-title":"J Leukoc Biol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"3402","DOI":"10.1128\/IAI.73.6.3402-3407.2005","article-title":"Host cytokine production, lymphoproliferation, and antibody responses during the course of <italic>Ancylostoma ceylanicum<\/italic> infection in the Golden Syrian hamster","volume":"73","author":"S Mendez","year":"2005","journal-title":"Infect Immun"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1111\/j.1365-3024.2006.00821.x","article-title":"Comparative immunology of human and animal models of hookworm infection","volume":"28","author":"RT Fujiwara","year":"2006","journal-title":"Parasite Immunol"},{"key":"ref44","first-page":"1154","article-title":"Antibody response in Kwashiorkor","volume":"52","author":"V Reddy","year":"1964","journal-title":"Indian J Med Res"},{"key":"ref45","first-page":"255","article-title":"Immunological responses in malnourished children","volume":"14","author":"V Reddy","year":"1977","journal-title":"Indian Pediatr"},{"key":"ref46","first-page":"186","article-title":"Immunoglobulins in Kwashiorkor","volume":"73","author":"GH Aref","year":"1970","journal-title":"J Trop Med Hyg"},{"key":"ref47","first-page":"108","article-title":"Hookworm anaemia and intestinal malabsorption associated with hookworm infestation","volume":"19","author":"AK Saraya","year":"1975","journal-title":"Prog Drug Res"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1136\/gut.10.4.293","article-title":"Role of parasites in the pathogenesis of intestinal malabsorption in hookworm disease","volume":"10","author":"BN Tandon","year":"1969","journal-title":"Gut"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1093\/jn\/120.suppl_11.1496","article-title":"Assessment of protein nutritional status","volume":"120 Suppl 11","author":"VR Young","year":"1990","journal-title":"J Nutr"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/j.1651-2227.2012.02613.x","article-title":"Undernutrition in Nepalese children: a biochemical and haematological study","volume":"101","author":"A Ghosh","year":"2012","journal-title":"Acta Paediatr"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"7078","DOI":"10.1073\/pnas.97.13.7078","article-title":"Suppressed T helper 2 immunity and prolonged survival of a nematode parasite in protein-malnourished mice","volume":"97","author":"R Ing","year":"2000","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0003184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,16]],"date-time":"2023-07-16T19:57:21Z","timestamp":1689537441000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0003184"}},"subtitle":[],"editor":[{"given":"Peter J.","family":"Hotez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,9,25]]},"references-count":51,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2014,9,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0003184","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,25]]}}}