{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T20:53:21Z","timestamp":1763499201970},"reference-count":71,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T00:00:00Z","timestamp":1411603200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0003196","type":"journal-article","created":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T19:24:42Z","timestamp":1411673082000},"page":"e3196","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["Evaluation of the Murine Immune Response to Xenopsylla cheopis Flea Saliva and Its Effect on Transmission of Yersinia pestis"],"prefix":"10.1371","volume":"8","author":[{"given":"Christopher F.","family":"Bosio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Austin K.","family":"Viall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clayton O.","family":"Jarrett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald","family":"Gardner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"Rood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. Joseph","family":"Hinnebusch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,9,25]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1086\/429931","article-title":"Poor vector competence of fleas and the evolution of hypervirulence in <italic>Yersinia pestis<\/italic>","volume":"191","author":"EA Lorange","year":"2005","journal-title":"J Infect Dis"},{"key":"ref2","first-page":"197","article-title":"The evolution of flea-borne transmission in <italic>Yersinia pestis<\/italic>","volume":"7","author":"BJ Hinnebusch","year":"2005","journal-title":"Current Issues in Molecular Biology"},{"key":"ref3","unstructured":"Bergman DK (1996) Mouthparts and feeding mechanisms of haematophagous arthropods. Wallingford, UK: CAB International."},{"key":"ref4","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1095-8312.1979.tb00055.x","article-title":"The evolution of insect\/vertebrate associations","volume":"12","author":"JK Waage","year":"1979","journal-title":"Biol J Linnean Soc"},{"key":"ref5","first-page":"59","article-title":"From sialomes to the sialoverse: an insight into salivary potion of blood-feeding insects","volume":"37","author":"JM Ribeiro","year":"2009","journal-title":"Advances in Insect Physiology"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"375","DOI":"10.2174\/1568006043335862","article-title":"Antihemostatic strategies of blood-feeding arthropods","volume":"4","author":"DE Champagne","year":"2004","journal-title":"Current Drug Targets - Cardiovascular and Haematological Disorders"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1365-3024.2006.00807.x","article-title":"The immunomodulatory factors of arthropod saliva and the potential for these factors to serve as vaccine targets to prevent pathogen transmission","volume":"28","author":"RG Titus","year":"2006","journal-title":"Parasite Immunol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"311","DOI":"10.2307\/1313614","article-title":"Modulation of the host immune response by ectoparasitic arthropods","volume":"49","author":"SK Wikel","year":"1999","journal-title":"BioScience"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1126\/science.3344436","article-title":"Salivary gland lysates from the sand fly <italic>Lutzomyia longipalpis<\/italic> enhance <italic>Leishmania<\/italic> infectivity","volume":"239","author":"RG Titus","year":"1988","journal-title":"Science"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1084\/jem.188.10.1941","article-title":"Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva preexposure on the long-term outcome of <italic>Leishmania major<\/italic> infection in the mouse ear dermis","volume":"188","author":"Y Belkaid","year":"1998","journal-title":"J Exp Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1128\/IAI.72.3.1240-1247.2004","article-title":"Sand fly saliva enhances <italic>Leishmania amazonensis<\/italic> infection by modulating interleukin-10 production","volume":"72","author":"NB Norsworthy","year":"2004","journal-title":"Infect Immun"},{"key":"ref12","first-page":"1276","article-title":"Coinoculation of <italic>Borrelia<\/italic> spp. with tick salivary gland lysate enhances spirochete load in mice and is tick species-specific","volume":"88","author":"NS Zeidner","year":"2002","journal-title":"J Parasitol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/jmedent\/35.3.261","article-title":"Mosquito feeding-induced enhancement of Cache Valley virus (Bunyaviridae) infection in mice","volume":"35","author":"JF Edwards","year":"1998","journal-title":"J Med Entomol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1365-2915.1993.tb00674.x","article-title":"Enhancement of tick-borne encephalitis transmission by tick salivary gland extracts","volume":"7","author":"M Labuda","year":"1993","journal-title":"Med Vet Entomol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1046\/j.1365-3024.2000.00326.x","article-title":"Potentiation of vesicular stomatitus New Jersey virus infection on mice by mosquito saliva","volume":"22","author":"KH Limesand","year":"2000","journal-title":"Parasite Immunol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"4285","DOI":"10.1128\/IAI.67.8.4285-4289.1999","article-title":"Infectivity of <italic>Plasmodium berghei<\/italic> sporozoites delivered by intravenous inocluation versus mosquito bite: implications for sporozoite vaccine trials","volume":"67","author":"JA Vaughan","year":"1999","journal-title":"Infect Immun"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1126\/science.290.5495.1351","article-title":"Protection against cutaneous leishmaniasis resulting from bites of uninfected sandflies","volume":"290","author":"S Kamhawi","year":"2000","journal-title":"Science"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1128\/IAI.65.1.335-338.1997","article-title":"Infestation with pathogen-free nymphs of the tick <italic>Ixodes scapularis<\/italic> induces host resistance to transmission of <italic>Borrelia burgdorferi<\/italic> by ticks","volume":"65","author":"S Wikel","year":"1997","journal-title":"Infection and Immunity"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1128\/IAI.01928-06","article-title":"Uninfected mosquito bites confer protection against infection with malaria parasites","volume":"75","author":"MJ Donovan","year":"2007","journal-title":"Infect Immun"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"e1171","DOI":"10.1371\/journal.pone.0001171","article-title":"Prior exposure to uninfected mosquitoes enhances mortality in naturally-transmitted West Nile virus infection","volume":"2","author":"BS Schneider","year":"2007","journal-title":"PLos ONE"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"6324","DOI":"10.1128\/IAI.01046-06","article-title":"Tsetse fly saliva accelerates the onset of <italic>Trypanosoma brucei<\/italic> infection in a mouse model associated with a reduced inflammatory response","volume":"74","author":"G Caljon","year":"2006","journal-title":"Infect immun"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1128\/IAI.00807-09","article-title":"Neither mosquito saliva nor immunity to saliva has a detectable effect on the infectivity of <italic>Plasmodium<\/italic> sporozoites injected into mice","volume":"78","author":"C Kebaier","year":"2010","journal-title":"Infect Immun"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.1128\/AEM.64.11.4596-4599.1998","article-title":"Effect of prior exposure to noninfected ticks on susceptibility of mice to Lyme disease spirochetes","volume":"64","author":"D Richter","year":"1998","journal-title":"Appl Environ Microbiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1128\/JVI.01112-10","article-title":"Mosquito saliva causes enhancement of West Nile virus infection in mice","volume":"85","author":"LM Styer","year":"2011","journal-title":"J Virol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1186\/1471-2164-8-102","article-title":"An insight into the sialome of the oriental rat flea, <italic>Xenopsylla cheopis<\/italic> (Rots)","volume":"8","author":"JF Andersen","year":"2007","journal-title":"BMC Genomics"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"e44612","DOI":"10.1371\/journal.pone.0044612","article-title":"An insight into the sialotranscriptome of the cat flea, <italic>Ctenocephalides felis<\/italic>","volume":"7","author":"JM Ribeiro","year":"2012","journal-title":"PLoS One"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"64","DOI":"10.4049\/jimmunol.87.1.64","article-title":"Experimental comparison of the immunogenicity of antigens in the residue of ultrasonated avirulent <italic>Pasteurella pestis<\/italic> with the vaccine prepared with the killed virulent whole organisms","volume":"87","author":"TH Chen","year":"1961","journal-title":"J Immunol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1093\/jmedent\/26.4.342","article-title":"Use of DNA hybridization probes for detection of the plague bacillus (<italic>Yersinia pestis<\/italic>) in fleas (Siphonaptera: Pulicidae and Ceratophyllidae)","volume":"26","author":"RE Thomas","year":"1989","journal-title":"J Med Entomol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0022-1759(96)00117-2","article-title":"A method to recover, enumerate and identify lymphomyeloid cells present in an inflammatory dermal site: a study in laboratory mice","volume":"199","author":"Y Belkaid","year":"1996","journal-title":"J Immunol Methods"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.jim.2006.01.022","article-title":"Anatomy and nomenclature of murine lymph nodes: Descriptive study and nomenclatory standardization in BALB\/cAnNCrl mice","volume":"312","author":"W Van den Broeck","year":"2006","journal-title":"J Immunol Methods"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"4034","DOI":"10.1128\/IAI.00606-12","article-title":"Kinetics of innate immune response to <italic>Yersinia pestis<\/italic> after intradermal infection in a mouse model","volume":"80","author":"CF Bosio","year":"2012","journal-title":"Infect Immun"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1046\/j.1365-2567.1996.d01-711.x","article-title":"Priming differentially regulates neutrophil adhesion molecule expression\/function","volume":"89","author":"AM Condliffe","year":"1996","journal-title":"Immunol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"e1002040","DOI":"10.1371\/journal.ppat.1002040","article-title":"Human neutrophil clearance of bacterial pathogens triggers anti-microbial \u03b3\u03b4 T cell responses in early infection","volume":"7","author":"MS Davey","year":"2011","journal-title":"PLoS Pathog"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1093\/rheumatology\/kem039","article-title":"Neutrophils of healthy subjects with a history of reactive arthritis show enhanced responsiveness, as defined by CD11b expression in adherent and non-adherent whole blood cultures","volume":"46","author":"K Kuuliala","year":"2007","journal-title":"Rheumatology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1515\/CCLM.2004.050","article-title":"Expression of activation molecules in neutrophils, monocytes and lymphocytes from patients with unstable angina treated with stent implantation","volume":"42","author":"V S\u00e1nchez-Margalet","year":"2004","journal-title":"Clin Chem Lab Med"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1086\/314456","article-title":"Evaluation of the role of <italic>Yersinia pestis<\/italic> plasminogen activator and other plasmid-encoded factors in temperature-dependent blockage of the flea","volume":"178","author":"BJ Hinnebusch","year":"1998","journal-title":"J Infect Dis"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1126\/science.273.5273.367","article-title":"Role of the <italic>Yersinia pestis<\/italic> hemin storage (<italic>hms<\/italic>) locus in the transmission of plague by fleas","volume":"273","author":"BJ Hinnebusch","year":"1996","journal-title":"Science"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1126\/science.2783496","article-title":"A novel vasodilatory peptide from the salivary glands of the sand fly <italic>Lutzomyia longipalpis<\/italic>","volume":"243","author":"JM Ribeiro","year":"1989","journal-title":"Science"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"3932","DOI":"10.4049\/jimmunol.174.7.3932","article-title":"<italic>Anopheles<\/italic> mosquito bites activate cutaneous mast cells leading to a local inflammatory response and lymph node hyperplasia","volume":"174","author":"CE Demeure","year":"2005","journal-title":"J Immunol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"700","DOI":"10.3181\/00379727-108-27040","article-title":"Skin reactivity in guinea pigs sensitized to flea bites: The sequence of reactions","volume":"108","author":"E Benjamini","year":"1961","journal-title":"Proc Soc Exp Biol Med"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1365-2915.2008.00793.x","article-title":"Sensitivity to bites by the bedbug, <italic>Cimex lectularius<\/italic>","volume":"23","author":"K Reinhardt","year":"2009","journal-title":"Med Vet Entomol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0014-4894(64)90042-6","article-title":"Histologic studies of guinea pig skin: Different stages of allergic reactivity to flea bites","volume":"15","author":"DH Larrivee","year":"1964","journal-title":"Exp Parasitol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.vaccine.2005.07.085","article-title":"From transcriptome to immunome: identification of DTH inducing proteins from a <italic>Phlebotomus ariasi<\/italic> salivary gland cDNA library","volume":"24","author":"F Oliveira","year":"2006","journal-title":"Vaccine"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1146\/annurev.en.13.010168.001033","article-title":"The allergic responses to insect bites","volume":"13","author":"BF Feingold","year":"1968","journal-title":"Ann Rev Entomol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0014-4894(85)90060-8","article-title":"<italic>Xenopsylla cheopis<\/italic>: cellular expression of hypersensitivity in guinea pigs","volume":"59","author":"CM Johnston","year":"1985","journal-title":"Exp Parasitol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.vetimm.2005.10.008","article-title":"Immune dysregulation on flea allergy dermatitis - a model for the immunopathogenesis of allergic dermatitis","volume":"110","author":"K Wuersch","year":"2006","journal-title":"Vet Immunol Immunopathol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/jmedent\/27.4.519","article-title":"Distribution of immunoglobulin G and E antibody levels to salivary gland extracts of <italic>Aedes albopictus<\/italic> (Diptera: Culicidae) in several age groups of a Japanese population","volume":"27","author":"E Konishi","year":"1990","journal-title":"J Med Entomol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.ijpara.2006.05.002","article-title":"Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment","volume":"36","author":"G Caljon","year":"2006","journal-title":"Int J Parasitol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1093\/jmedent\/30.4.725","article-title":"Antibody responses of BALB\/c mice to salivary antigens of hematophagous black flies (Diptera: Simuliidae)","volume":"30","author":"ML Cross","year":"1993","journal-title":"J Med Entomol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/vbz.2007.0214","article-title":"Kinetics of canine antibody response to saliva of the sand fly <italic>Lutzomyia longipalpis<\/italic>","volume":"8","author":"J Hostomska","year":"2008","journal-title":"Vector Borne Zoonotic Dis"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S1081-1206(10)63262-0","article-title":"Immunologic mechanisms in mosquito allergy: correlation of skin reactions with specific IgE and IgG antibodies and lymphocyte proliferation response to mosquito antigens","volume":"77","author":"Z Peng","year":"1996","journal-title":"Ann Allergy Asthma Immunol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/0014-4894(60)90005-9","article-title":"Allergy to flea bites. I. Experimental induction of flea-bite sensitivity in guinea pigs","volume":"9","author":"BW Hudson","year":"1960","journal-title":"Exp Parasitol"},{"key":"ref53","first-page":"E1","article-title":"Overview of flea allergy dematitis","volume":"31","author":"A Lam","year":"2009","journal-title":"Compend Contin Educ Vet"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1093\/jmedent\/26.5.449","article-title":"Rat leucocyte response to the bites of rat fleas (Siphonaptera: Pulicidae)","volume":"26","author":"JA Vaughan","year":"1989","journal-title":"J Med Entomol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1046\/j.1365-3024.2001.00356.x","article-title":"Th2 polarization of the immune response of BALB\/c mice to <italic>Ixodes ricinus<\/italic> instars, importance of several antigens in activation of specific Th2 subpopulations","volume":"23","author":"N Merji","year":"2001","journal-title":"Parasite Immunol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"5571","DOI":"10.4049\/jimmunol.161.10.5571","article-title":"<italic>Phlebotomus paptasi<\/italic> sand fly salivary gland lysate down-regulates a Th1, but up-regulates a Th2, response in mice infected with <italic>Leishmania major<\/italic>","volume":"161","author":"ML Mbow","year":"1998","journal-title":"J Immunol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1089\/vim.2004.17.565","article-title":"<italic>Aedes aegypti<\/italic> salivary gland extracts modulate anti-viral and T<sub>H<\/sub>1\/T<sub>H<\/sub>2 cytokine responses to Sindbis virus infection","volume":"17","author":"BS Schneider","year":"2004","journal-title":"Viral Immunol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1046\/j.1365-3024.1997.d01-140.x","article-title":"Salivary antigens of the cat flea, <italic>Ctenocephalides felis felis<\/italic>","volume":"19","author":"SE Lee","year":"1997","journal-title":"Parasite Immunol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/j.cell.2009.11.001","article-title":"Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo","volume":"139","author":"F M\u00fcller","year":"2009","journal-title":"Cell"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1073\/pnas.0507195103","article-title":"Polyphosphate modulates blood coagulation and fibrinolysis","volume":"103","author":"SA Smith","year":"2006","journal-title":"PNAS"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"5972","DOI":"10.1182\/blood-2012-03-306605","article-title":"Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation","volume":"119","author":"JH Morrissey","year":"2012","journal-title":"Blood"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1365-3024.1993.tb00586.x","article-title":"Characterization of allergens of the cat flea, <italic>Ctenocephalides felis<\/italic>: detection and frequency of IgE antibodies in canine sera","volume":"15","author":"WK Greene","year":"1993","journal-title":"Parasite Immunol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0165-2427(85)90082-0","article-title":"IgE and IgG antibodies to flea antigen in differing dog populations","volume":"8","author":"REW Halliwell","year":"1985","journal-title":"Vet Immunol Immunopathol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"278","DOI":"10.4269\/ajtmh.2004.70.278","article-title":"Negative effect of antibodies against maxadilan on the fitness of the sand fly vector of American visceral leishmaniasis","volume":"70","author":"RS Milleron","year":"2004","journal-title":"Am J Trop Med Hyg"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1146\/annurev.en.27.010182.000321","article-title":"Immune responses to arthropods and their products","volume":"27","author":"SK Wikel","year":"1982","journal-title":"Ann Rev Entomol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/BF01922254","article-title":"Effects and duration of resistance acquired by rabbits on feeding and egglaying in <italic>Ixodes ricinus<\/italic> L","volume":"33","author":"J Bowessidjaou","year":"1977","journal-title":"Experientia"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0020-7519(97)00152-5","article-title":"The effect of anti-sandfly saliva antibodies on <italic>Phlebotomus argentipes<\/italic> and <italic>Leishmania donovani<\/italic>","volume":"28","author":"KN Ghosh","year":"1998","journal-title":"Int J Parasitol"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"e1688","DOI":"10.1371\/journal.pone.0001688","article-title":"Defective innate cell response and lymph node infiltration specify <italic>Yersinia pestis<\/italic> infection","volume":"3","author":"F Guinet","year":"2008","journal-title":"PLoS ONE"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"5086","DOI":"10.1128\/IAI.00256-10","article-title":"Transcriptomic and innate immune responses to <italic>Yersinia pestis<\/italic> in the lymph node during bubonic plague","volume":"78","author":"JE Comer","year":"2010","journal-title":"Infect Immun"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"e00170","DOI":"10.1128\/mBio.00170-13","article-title":"<italic>Yersinia pestis<\/italic> subverts the dermal neutrophil response in a mouse model of bubonic plague","volume":"4","author":"JG Shannon","year":"2013","journal-title":"mBio"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"5526","DOI":"10.1073\/pnas.0509544103","article-title":"Role of the <italic>Yersinia pestis<\/italic> plasminogen activator in the incidence of distinct septicemic and bubonic forms of flea-borne plague","volume":"103","author":"F Sebbane","year":"2006","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0003196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T23:24:13Z","timestamp":1717370653000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0003196"}},"subtitle":[],"editor":[{"given":"Pamela L. C.","family":"Small","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,9,25]]},"references-count":71,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2014,9,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0003196","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9,25]]}}}