{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T07:46:12Z","timestamp":1789717572934,"version":"4.0.1"},"reference-count":66,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T00:00:00Z","timestamp":1414022400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0003273","type":"journal-article","created":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T17:09:50Z","timestamp":1414084190000},"page":"e3273","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":51,"title":["IgG1 as a Potential Biomarker of Post-chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test"],"prefix":"10.1371","volume":"8","author":[{"given":"Tapan","family":"Bhattacharyya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armon","family":"Ayandeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew K.","family":"Falconar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam","family":"Sundar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayda","family":"El-Safi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marissa A.","family":"Gripenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duncan E.","family":"Bowes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Thunissen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Om Prakash","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osama","family":"Eisa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfarazdeg","family":"Saad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Silva Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marleen","family":"Boelaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Mertens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A.","family":"Miles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,10,23]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e35671","DOI":"10.1371\/journal.pone.0035671","article-title":"Leishmaniasis worldwide and global estimates of its incidence","volume":"7","author":"J Alvar","year":"2012","journal-title":"PLoS One"},{"key":"ref2","unstructured":"World Health Organization (2010) Control of the Leishmaniases. World Health Organization."},{"key":"ref3","doi-asserted-by":"crossref","first-page":"v1","DOI":"10.1136\/sti.2006.024265","article-title":"Rapid tests for sexually transmitted infections (STIs): the way forward","volume":"82","author":"RW Peeling","year":"2006","journal-title":"Sex Transm Infect"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S0140-6736(97)04350-X","article-title":"Rapid accurate field diagnosis of Indian visceral leishmaniasis","volume":"351","author":"S Sundar","year":"1998","journal-title":"The Lancet"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1136\/bmj.38917.503056.7C","article-title":"A meta-analysis of the diagnostic performance of the direct agglutination test and rK39 dipstick for visceral leishmaniasis","volume":"333","author":"F Chappuis","year":"2006","journal-title":"BMJ"},{"key":"ref6","first-page":"CD009135","article-title":"Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease","volume":"6","author":"M Boelaert","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.trstmh.2010.09.006","article-title":"Diagnosis of visceral leishmaniasis","volume":"105","author":"P Srivastava","year":"2011","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref8","unstructured":"World Health Organization (2012) Technical Report Series 975. Research Priorities for Chagas Disease, Human African Trypanosomiasis and Leishmaniasis. Geneva, Switzerland: World Health Organization."},{"key":"ref9","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1073\/pnas.90.2.775","article-title":"Molecular characterization of a kinesin-related antigen of Leishmania chagasi that detects specific antibody in African and American visceral leishmaniasis","volume":"90","author":"JM Burns Jr","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.trstmh.2007.09.003","article-title":"Diagnostic tests for kala-azar: a multi-centre study of the freeze-dried DAT, rK39 strip test and KAtex in East Africa and the Indian subcontinent","volume":"102","author":"M Boelaert","year":"2008","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1093\/cid\/cis716","article-title":"A global comparative evaluation of commercial immunochromatographic rapid diagnostic tests for visceral leishmaniasis","volume":"55","author":"J Cunningham","year":"2012","journal-title":"Clin Infect Dis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"e2057","DOI":"10.1371\/journal.pntd.0002057","article-title":"Comparison of visceral leishmaniasis diagnostic antigens in African and Asian Leishmania donovani reveals extensive diversity and region-specific polymorphisms","volume":"7","author":"T Bhattacharyya","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"e2675","DOI":"10.1371\/journal.pntd.0002675","article-title":"Significantly Lower Anti-Leishmania IgG Responses in Sudanese versus Indian Visceral Leishmaniasis","volume":"8","author":"T Bhattacharyya","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"e822","DOI":"10.1371\/journal.pntd.0000822","article-title":"Design, development and evaluation of rK28-based point-of-care tests for improving rapid diagnosis of visceral leishmaniasis","volume":"4","author":"S Pattabhi","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"S41","DOI":"10.1016\/j.jaci.2009.09.046","article-title":"Structure and function of immunoglobulins","volume":"125","author":"HW Schroeder Jr","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"ref16","first-page":"14","article-title":"Characterization of the humoral immune response in Sudanese leishmaniasis: specific antibody detected by class- and subclass-specific reagents","volume":"64","author":"EM el Amin","year":"1986","journal-title":"Clin Exp Immunol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1365-2249.1994.tb06526.x","article-title":"The significance of blood levels of IgM, IgA, IgG and IgG subclasses in Sudanese visceral leishmaniasis patients","volume":"95","author":"AM Elassad","year":"1994","journal-title":"Clin Exp Immunol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1128\/CDLI.2.3.291-296.1995","article-title":"Immunoglobulin G subclass-specific antileishmanial antibody responses in Indian kala-azar and post-kala-azar dermal leishmaniasis","volume":"2","author":"AK Ghosh","year":"1995","journal-title":"Clin Diagn Lab Immunol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1365-2249.1995.tb03603.x","article-title":"Differing antibody IgG isotypes in the polar forms of leprosy and cutaneous leishmaniasis characterized by antigen-specific T cell anergy","volume":"100","author":"M Ulrich","year":"1995","journal-title":"Clin Exp Immunol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0165-2478(96)02529-1","article-title":"Visceral leishmaniasis in Somalia. Significance of IgG subclasses and of IgE response","volume":"50","author":"SA Shiddo","year":"1996","journal-title":"Immunol Lett"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1046\/j.1365-2249.1998.00752.x","article-title":"Distribution of IgG subclasses in antimonial unresponsive Indian kala-azar patients","volume":"114","author":"M Chatterjee","year":"1998","journal-title":"Clin Exp Immunol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1128\/CDLI.6.2.231-235.1999","article-title":"Immunoglobulin subclass distribution and diagnostic value of Leishmania donovani antigen-specific immunoglobulin G3 in Indian kala-azar patients","volume":"6","author":"K Anam","year":"1999","journal-title":"Clin Diagn Lab Immunol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"6663","DOI":"10.1128\/IAI.67.12.6663-6669.1999","article-title":"Differential decline in Leishmania membrane antigen-specific immunoglobulin G (IgG), IgM, IgE, and IgG subclass antibodies in Indian kala-azar patients after chemotherapy","volume":"67","author":"K Anam","year":"1999","journal-title":"Infect Immun"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0165-2478(99)00146-7","article-title":"The humoral immune response to the kinetoplastid membrane protein-11 in patients with American leishmaniasis and Chagas disease: prevalence of IgG subclasses and mapping of epitopes","volume":"70","author":"C Trujillo","year":"1999","journal-title":"Immunol Lett"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1086\/320994","article-title":"Distinct immunity in patients with visceral leishmaniasis from that in subclinically infected and drug-cured people: implications for the mechanism underlying drug cure","volume":"184","author":"A Hailu","year":"2001","journal-title":"J Infect Dis"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1128\/IAI.72.2.863-870.2004","article-title":"Characterization of Immunoglobulin G and Its Subclass Response to Indian Kala-Azar Infection before and after Chemotherapy","volume":"72","author":"R Ravindran","year":"2004","journal-title":"Infection and Immunity"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1128\/JCM.43.3.1269-1277.2005","article-title":"Leishmania promastigote membrane antigen-based enzyme-linked immunosorbent assay and immunoblotting for differential diagnosis of Indian post-kala-azar dermal leishmaniasis","volume":"43","author":"S Saha","year":"2005","journal-title":"J Clin Microbiol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1111\/j.1365-3024.2008.01036.x","article-title":"Elevated levels of IgG3 and IgG4 subclass in paediatric cases of kala azar","volume":"30","author":"NA Ansari","year":"2008","journal-title":"Parasite Immunol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1086\/588387","article-title":"Increased levels of interleukin-10 and IgG3 are hallmarks of Indian post-kala-azar dermal leishmaniasis","volume":"197","author":"S Ganguly","year":"2008","journal-title":"J Infect Dis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jim.2010.06.011","article-title":"Anti-Leishmania chagasi immunoglobulin G3 detected by flow cytometry for early cure assessment in American visceral leishmaniasis","volume":"360","author":"IT Gomes","year":"2010","journal-title":"J Immunol Methods"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.trstmh.2012.07.005","article-title":"Evaluation of serological markers to monitor the disease status of Indian post kala-azar dermal leishmaniasis","volume":"106","author":"D Mukhopadhyay","year":"2012","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"573","DOI":"10.4269\/ajtmh.2007.76.573","article-title":"Multiple hybrid genotypes of Leishmania (viannia) in a focus of mucocutaneous Leishmaniasis","volume":"76","author":"D Nolder","year":"2007","journal-title":"Am J Trop Med Hyg"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1128\/CVI.00473-10","article-title":"Persistence of Leishmania donovani antibodies in past visceral leishmaniasis cases in India","volume":"18","author":"K Gidwani","year":"2011","journal-title":"Clin Vaccine Immunol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"725","DOI":"10.4161\/hv.19542","article-title":"Dynamics of the antibodies in cohorts of cured cases of visceral leishmaniasis: its implication on the validity of serological test, value in prognosis and in post therapeutic assessment","volume":"8","author":"RR Patil","year":"2012","journal-title":"Hum Vaccin Immunother"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"739","DOI":"10.4269\/ajtmh.2006.75.739","article-title":"Immunologic tests in patients after clinical cure of visceral leishmaniasis","volume":"75","author":"L De Almeida Silva","year":"2006","journal-title":"Am J Trop Med Hyg"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1128\/CDLI.5.5.717-720.1998","article-title":"rK39 enzyme-linked immunosorbent assay for diagnosis of Leishmania donovani infection","volume":"5","author":"EE Zijlstra","year":"1998","journal-title":"Clin Diagn Lab Immunol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1046\/j.1365-3156.2001.00680.x","article-title":"Diagnosing visceral leishmaniasis with the recombinant K39 strip test: experience from the Sudan","volume":"6","author":"EE Zijlstra","year":"2001","journal-title":"Trop Med Int Health"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"e2657","DOI":"10.1371\/journal.pntd.0002657","article-title":"Strong Association between Serological Status and Probability of Progression to Clinical Visceral Leishmaniasis in Prospective Cohort Studies in India and Nepal","volume":"8","author":"E Hasker","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"O374","DOI":"10.1111\/1469-0691.12421","article-title":"Biomarkers for intracellular pathogens: establishing tools as vaccine and therapeutic endpoints for visceral leishmaniasis","volume":"20","author":"AC Vallur","year":"2013","journal-title":"Clin Microbiol Infect"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.trstmh.2011.08.005","article-title":"Asymptomatic infection of visceral leishmaniasis in hyperendemic areas of Vaishali district, Bihar, India: a challenge to kala-azar elimination programmes","volume":"105","author":"VN Das","year":"2011","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"e2053","DOI":"10.1371\/journal.pntd.0002053","article-title":"Latent infection with Leishmania donovani in highly endemic villages in Bihar, India","volume":"7","author":"E Hasker","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"e87641","DOI":"10.1371\/journal.pone.0087641","article-title":"Risk Factors for Visceral Leishmaniasis and Asymptomatic Leishmania donovani Infection in India and Nepal","volume":"9","author":"A Picado","year":"2014","journal-title":"PLoS One"},{"key":"ref43","first-page":"568","article-title":"Predicting kala-azar disease manifestations in asymptomatic patients with latent Leishmania donovani infection by detection of antibody against recombinant K39 antigen","volume":"9","author":"S Singh","year":"2002","journal-title":"Clin Diagn Lab Immunol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"826","DOI":"10.4269\/ajtmh.1994.51.826","article-title":"Endemic kala-azar in eastern Sudan: a longitudinal study on the incidence of clinical and subclinical infection and post-kala-azar dermal leishmaniasis","volume":"51","author":"EE Zijlstra","year":"1994","journal-title":"Am J Trop Med Hyg"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0035-9203(95)90070-5","article-title":"A prospective sero-epidemiological study of visceral leishmaniasis in Baringo District, Rift Valley Province, Kenya","volume":"89","author":"KU Schaefer","year":"1995","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1093\/infdis\/166.5.1124","article-title":"Epidemiology of visceral leishmaniasis in northeast Brazil","volume":"166","author":"TG Evans","year":"1992","journal-title":"J Infect Dis"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"909","DOI":"10.4269\/ajtmh.2007.76.909","article-title":"The epidemiology of visceral leishmaniasis and asymptomatic leishmanial infection in a highly endemic Bangladeshi village","volume":"76","author":"C Bern","year":"2007","journal-title":"Am J Trop Med Hyg"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"e1284","DOI":"10.1371\/journal.pntd.0001284","article-title":"Incidence of symptomatic and asymptomatic Leishmania donovani infections in high-endemic foci in India and Nepal: a prospective study","volume":"5","author":"B Ostyn","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0035-9203(02)90278-6","article-title":"A leishmanin skin test survey in the human population of l'Alacanti region (Spain): implications for the epidemiology of Leishmania infantum infection in southern Europe","volume":"96","author":"L Moral","year":"2002","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/0035-9203(95)90449-2","article-title":"Analysis of immunoglobulin G subclass in the serum antibody responses of alveolar echinococcosis patients after surgical treatment and chemotherapy as an aid to assessing the outcome","volume":"89","author":"H Wen","year":"1995","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"329","DOI":"10.4269\/ajtmh.2004.70.329","article-title":"Human cystic echinococcosis: evaluation of post-treatment serologic follow-up by IgG subclass antibody detection","volume":"70","author":"SD Lawn","year":"2004","journal-title":"Am J Trop Med Hyg"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1128\/CVI.00026-10","article-title":"Immunoglobulin G subclass responses to recombinant Em18 in the follow-up of patients with alveolar echinococcosis in different clinical stages","volume":"17","author":"D Tappe","year":"2010","journal-title":"Clin Vaccine Immunol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/INF.0b013e3182703460","article-title":"Association between IgG subclasses against Toxoplasma gondii and clinical signs in newborns with congenital toxoplasmosis","volume":"32","author":"CH de Souza-e-Silva","year":"2013","journal-title":"Pediatr Infect Dis J"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.imlet.2012.02.008","article-title":"Analysis of IgG subclasses (IgG1 and IgG3) to recombinant SAG2A protein from Toxoplasma gondii in sequential serum samples from patients with toxoplasmosis","volume":"143","author":"SS Santana","year":"2012","journal-title":"Immunol Lett"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"406","DOI":"10.4269\/ajtmh.1998.58.406","article-title":"IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2): increasing prevalence with age and association with clinical immunity to malaria","volume":"58","author":"RR Taylor","year":"1998","journal-title":"Am J Trop Med Hyg"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1128\/IAI.01129-08","article-title":"Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illness","volume":"77","author":"DI Stanisic","year":"2009","journal-title":"Infect Immun"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1186\/1475-2875-7-186","article-title":"Pattern of humoral immune response to Plasmodium falciparum blood stages in individuals presenting different clinical expressions of malaria","volume":"7","author":"FM Leoratti","year":"2008","journal-title":"Malar J"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1034\/j.1600-065X.2000.17815.x","article-title":"Molecular basis of IgG subclass deficiency","volume":"178","author":"Q Pan","year":"2000","journal-title":"Immunol Rev"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1111\/j.1365-3024.2012.01379.x","article-title":"Decrease in anti-Leishmania IgG3 and IgG1 after cutaneous leishmaniasis lesion healing is correlated with the time of clinical cure","volume":"34","author":"GA Fagundes-Silva","year":"2012","journal-title":"Parasite Immunol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.humimm.2009.01.007","article-title":"Th1\/Th2 immune responses are associated with active cutaneous leishmaniasis and clinical cure is associated with strong interferon-gamma production","volume":"70","author":"LR Castellano","year":"2009","journal-title":"Hum Immunol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1099\/jmm.0.46667-0","article-title":"IgG and IgG subclass antibodies in patients with active cutaneous leishmaniasis","volume":"55","author":"H Ozbilge","year":"2006","journal-title":"J Med Microbiol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.4049\/jimmunol.180.3.1948","article-title":"Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice","volume":"180","author":"L Baudino","year":"2008","journal-title":"J Immunol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.vetpar.2007.03.037","article-title":"Immunoglobulin G subclass distribution in canine leishmaniosis: a review and analysis of pitfalls in interpretation","volume":"147","author":"MJ Day","year":"2007","journal-title":"Vet Parasitol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.vetimm.2009.07.017","article-title":"Comparison of monoclonal and polyclonal antibodies for the detection of canine IgG1 and IgG2, and associations with infection outcome in Leishmania infantum naturally infected dogs","volume":"133","author":"C Carson","year":"2010","journal-title":"Vet Immunol Immunopathol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.vetimm.2013.10.018","article-title":"Comparative functional characterization of canine IgG subclasses","volume":"157","author":"LM Bergeron","year":"2014","journal-title":"Vet Immunol Immunopathol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1093\/cid\/cit102","article-title":"Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance","volume":"56","author":"S Rijal","year":"2013","journal-title":"Clin Infect Dis"}],"container-title":["PLoS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0003273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,25]],"date-time":"2020-08-25T23:10:38Z","timestamp":1598397038000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0003273"}},"subtitle":[],"editor":[{"given":"Albert","family":"Picado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,10,23]]},"references-count":66,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2014,10,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0003273","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,23]]}}}