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WHO. http:\/\/apps.who.int\/iris\/bitstream\/10665\/95732\/1\/9789241209847_eng.pdf<\/ext-link>. Accessed 14 January 2014."},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1016\/S0140-6736(12)61729-2","article-title":"Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990\u20132010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"T Vos","year":"2012","journal-title":"Lancet"},{"key":"ref4","unstructured":"WHO (2013) The 17 neglected tropical diseases. World Heal Organ. http:\/\/www.who.int\/neglected_diseases\/diseases\/en\/<\/ext-link>. Accessed 5 September 2014."},{"key":"ref5","first-page":"1","article-title":"Control and surveillance of human African trypanosomiasis","year":"2013"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1186\/1756-3305-7-374","article-title":"Challenges towards the elimination of Human African Trypanosomiasis in the sleeping sickness focus of Campo in southern Cameroon","volume":"7","author":"G Simo","year":"2014","journal-title":"Parasit Vectors"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"e1002855","DOI":"10.1371\/journal.pcbi.1002855","article-title":"Identifying transmission cycles at the human-animal interface: the role of animal reservoirs in maintaining gambiense human african trypanosomiasis","volume":"9","author":"S Funk","year":"2013","journal-title":"PLoS Comput Biol"},{"key":"ref8","first-page":"1","article-title":"Accelerating Work to overcome the global impact of neglected tropical diseases: A roadmap for implementation","year":"2012"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"e359","DOI":"10.1016\/S2214-109X(14)70203-7","article-title":"Sensitivity and specificity of HAT Sero-K-SeT, a rapid diagnostic test for serodiagnosis of sleeping sickness caused by Trypanosoma brucei gambiense: a case-control study","volume":"2","author":"P B\u00fcscher","year":"2014","journal-title":"Lancet Glob Heal"},{"key":"ref10","unstructured":"Drugs for Neglected Diseases initiative (2014) DNDi\u2014Drugs for Neglected Diseases initiative. http:\/\/www.dndi.org\/<\/ext-link>. Accessed 5 September 2014."},{"key":"ref11","unstructured":"Foundation for Innovative New Diagnostics (n.d.) FIND\u2014Foundation for Innovative New Diagnostics. http:\/\/www.finddiagnostics.org\/<\/ext-link>. Accessed 5 September 2014."},{"key":"ref12","unstructured":"London Declaration (2013) From promises to progress: The First Annual Report on the London Declaration on NTDs. http:\/\/www.unitingtocombatntds.org\/reports\/promises-to-progress-EN.pdf<\/ext-link>. Accessed 14 March 2014."},{"key":"ref13","article-title":"Third","author":"MF Drummond","year":"2005"},{"key":"ref14","unstructured":"Scottish Intercollegiate Guidelines Network (SIGN) (n.d.). http:\/\/sign.ac.uk\/<\/ext-link>. Accessed 26 November 2013."},{"issue":"Suppl 1","key":"ref15","first-page":"237","article-title":"Comparative analysis of the costs and benefits of alternative disease control strategies: vector control versus human case finding and treatment","volume":"69","author":"AP Shaw","year":"1989","journal-title":"Ann Soc Belg Med Trop (1920)"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/hec.4730040404","article-title":"Cost-effectiveness analysis of alternative treatments of African gambiense trypanosomiasis in Uganda","volume":"4","author":"C Politi","year":"1995","journal-title":"Health Econ"},{"key":"ref17","first-page":"412","article-title":"Analytical tools for planning cost-effective surveillance in Gambiense sleeping sickness","volume":"61","author":"AP Shaw","year":"2001","journal-title":"Med Trop (Mars)"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1365-3156.2005.01391.x","article-title":"The efficiency of different detection strategies of human African trypanosomiasis by T. b. gambiense","volume":"10","author":"P Lutumba","year":"2005","journal-title":"Trop Med Int Health"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.3201\/eid1310.060358","article-title":"Cost-effectiveness of Algorithms for Confirmation Test of Human African Trypanosomiasis","volume":"13","author":"P Lutumba","year":"2007","journal-title":"Emerg Infect Dis"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"248","DOI":"10.3201\/eid1302.060075","article-title":"Human African trypanosomiasis in a rural community, Democratic Republic of Congo","volume":"13","author":"P Lutumba","year":"2007","journal-title":"Emerg Infect Dis"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1365-3156.2007.01999.x","article-title":"Eflornithine is a cost-effective alternative to melarsoprol for the treatment of second-stage human West African trypanosomiasis in Caxito, Angola","volume":"13","author":"J Robays","year":"2008","journal-title":"Trop Med Int Health"},{"key":"ref22","article-title":"Economic Analysis in Health Care","author":"S Morris","year":"2007"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1136\/bmj.38658.675243.94","article-title":"Achieving the millennium development goals for health: evaluation of current strategies and future priorities for improving health in developing countries","volume":"331","author":"DB Evans","year":"2005","journal-title":"Br Med J (Clinical Res Ed"},{"key":"ref24","unstructured":"WHO (n.d.) WHO | Cost-effectiveness thresholds. http:\/\/www.who.int\/choice\/costs\/CER_thresholds\/en\/index.html<\/ext-link>. Accessed 27 November 2013."},{"key":"ref25","unstructured":"World Health Organization (WHO) (n.d.) Microsoft Word\u2014A66_20-en.docx\u2014A66_20_Eng.pdf. http:\/\/www.who.int\/neglected_diseases\/A66_20_Eng.pdf<\/ext-link>. Accessed 5 September 2014."},{"key":"ref26","unstructured":"Bill & Melinda Gates Foundation (n.d.) Bill & Melinda Gates Foundation. http:\/\/www.gatesfoundation.org\/<\/ext-link>. Accessed 5 September 2014."},{"key":"ref27","unstructured":"Department for International Development (n.d.) Department for International Development\u2014GOV.UK. https:\/\/www.gov.uk\/government\/organisations\/department-for-international-development<\/ext-link>. Accessed 5 September 2014."},{"key":"ref28","unstructured":"Swiss Tropical and Public Health Institute (Swiss TPH) (2014) http:\/\/www.swisstph.ch\/<\/ext-link>. Accessed 5 September 2014."},{"key":"ref29","unstructured":"Liverpool School of Tropical Medicine (n.d.) LSTM\u2014Liverpool School of Tropical Medicine. http:\/\/www.lstmliverpool.ac.uk\/<\/ext-link>. Accessed 5 September 2014."},{"key":"ref30","first-page":"1255","article-title":"A community battle against a tropical endemic disease: supernatural beliefs and tsetse fly traps in the Congo","volume":"28","author":"M Leygues","year":"1989","journal-title":"La lutte Communaut contre une Endem Trop croyances surnaturelles pieges a tsetse au Congo"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"e2579","DOI":"10.1371\/journal.pntd.0002579","article-title":"Community acceptance of tsetse control baits: a qualitative study in Arua District, North West Uganda","volume":"7","author":"V Kovacic","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.socscimed.2014.03.012","article-title":"Changing landscapes, changing practice: Negotiating access to sleeping sickness services in a post-conflict society","volume":"120","author":"JJ Palmer","year":"2014","journal-title":"Soc Sci 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assessment of the economic importance of the tsetse species of Southern Nigeria and the Southern Cameroons based on their trypanosome infection rates and ecology","volume":"52","author":"AM JORDAN","year":"1961","journal-title":"Bull Entomol Res"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0921-8009(01)00202-6","article-title":"Evaluating contingent and actual contributions to a local public good: Tsetse control in the Yale agro-pastoral zone, Burkina Faso","volume":"39","author":"M Kamuanga","year":"2001","journal-title":"Ecol Econ"},{"key":"ref55","first-page":"185","article-title":"The trapping of tsetse flies (Diptera: Glossinidae). Improvement of a model: the Vavoua trap","volume":"41","author":"C Laveissiere","year":"1990","journal-title":"Rech sur les pieges a glossines (Diptera Glossinidae) Mise au point d\u2019un Model Econ le piege \u201cVavoua\u201d"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.3201\/eid1109.041020","article-title":"Trypanosomiasis control, Democratic Republic of Congo, 1993\u20132003","volume":"11","author":"P Lutumba","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"ref57","first-page":"470","article-title":"Validity, cost and feasibility of the mAECT and CTC confirmation tests after diagnosis of African of sleeping sickness","volume":"11","author":"P Lutumba","year":"2006","journal-title":"Validite, cout faisabilite la mAECT CTC comme tests confirmation dans la Detect la Trypanos Hum Africaine"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"e868","DOI":"10.1371\/journal.pntd.0000868","article-title":"Quantifying the burden of rhodesiense sleeping sickness in Urambo District, Tanzania","volume":"4","author":"LE Matemba","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0020-7519(01)00148-5","article-title":"Comparing apples and oranges\u2014model-based assessment of different tsetse-transmitted trypanosomosis control strategies","volume":"31","author":"JJ McDermott","year":"2001","journal-title":"Int J Parasitol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"e400","DOI":"10.1016\/j.ijid.2012.05.537","article-title":"Human African trypanosomiasis diagnosis in first-line health services of endemic countries, a systematic review","volume":"16","author":"P Mitashi","year":"2012","journal-title":"Int J Infect Dis"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"e1438","DOI":"10.1371\/journal.pntd.0001438","article-title":"Diagnostic accuracy of molecular amplification tests for human African trypanosomiasis\u2014systematic review","volume":"6","author":"CM Mugasa","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1080\/00034983.1991.11812566","article-title":"Description of a mono-screen trap for Glossina fuscipes fuscipes Newstead in Uganda","volume":"85","author":"JO Okoth","year":"1991","journal-title":"Ann Trop Med Parasitol"},{"issue":"Suppl 84","key":"ref63","first-page":"394","article-title":"The economics of trypanosomiasis control in western Zambia","author":"SN Putt","year":"1988","journal-title":"Acta Vet Scand"},{"key":"ref64","first-page":"422","article-title":"Cost of a national program to control human African trypanosomiasis in the high Mbomou region, Central African Republic","volume":"61","author":"JA Ruiz Postigo","year":"2001","journal-title":"Cout d\u2019un Proj d\u2019appui au Program Natl lutte contre la Trypanos Hum africaine dans le foyer du Haut Mbomou, Repub Centrafr"},{"key":"ref65","first-page":"369","article-title":"The Trypanosomiases. CAB International","author":"APM Shaw","year":"2004"},{"key":"ref66","unstructured":"Shaw A, Hendrickx G, Gilbert M, Mattioli R, Codjia V, et al. (2006) Mapping the benefits: a new decision tool for tsetse and trypanosomiasis interventions. Rome, Italy. http:\/\/www.fao.org\/ag\/againfo\/programmes\/en\/paat\/documents\/papers\/Paper_2006.pdf<\/ext-link>."},{"key":"ref67","unstructured":"Shaw A, Torr S, Waiswa C, Robinson T (2007) Comparable Costings of Alternatives for Dealing with Tsetse: Estimates for Uganda. Rome, Italy. http:\/\/www.fao.org\/ag\/againfo\/programmes\/en\/pplpi\/docarc\/wp40.pdf<\/ext-link>."},{"key":"ref68","first-page":"27","article-title":"Assessing the economics of animal trypanosomosis in Africa\u2014history and current perspectives","volume":"76","author":"APM Shaw","year":"2009","journal-title":"Onderstepoort J Vet Res"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.prevetmed.2012.12.014","article-title":"Estimating the costs of tsetse control options: an example for Uganda","volume":"110","author":"APM Shaw","year":"2013","journal-title":"Prev Vet Med"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"e1007","DOI":"10.1371\/journal.pntd.0001007","article-title":"The human African trypanosomiasis control and surveillance programme of the World Health Organization 2000\u20132009: the way forward","volume":"5","author":"PP Simarro","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1017\/S0031182012000169","article-title":"Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis","volume":"139","author":"PP Simarro","year":"2012","journal-title":"Parasitology"},{"key":"ref72","first-page":"312","article-title":"Cost-effectiveness of programs for sleeping sickness control. 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