{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T07:23:27Z","timestamp":1778743407112,"version":"3.51.4"},"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T00:00:00Z","timestamp":1473811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0004989","type":"journal-article","created":{"date-parts":[[2016,9,14]],"date-time":"2016-09-14T17:50:46Z","timestamp":1473875446000},"page":"e0004989","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Succinyl-CoA Synthetase: New Antigen Candidate of Bartonella bacilliformis"],"prefix":"10.1371","volume":"10","author":[{"given":"Cl\u00e1udia","family":"Gomes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noem\u00ed","family":"Palma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria J.","family":"Pons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel","family":"Magall\u00f3n-Tejada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Sandoval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Tinco-Valdez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Gutarra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juana","family":"del Valle-Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaquim","family":"Ruiz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Matsuoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2016,9,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"e1819","DOI":"10.1371\/journal.pntd.0001819","article-title":"Bartonella bacilliformis: a systematic review of the literature to guide the research agenda for elimination","volume":"6","author":"N Sanchez Clemente","year":"2012","journal-title":"PloS Negl Trop Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0891-5520(05)70215-4","article-title":"Bartonellosis\u2013new and old","volume":"14","author":"C Magui\u00f1a","year":"2000","journal-title":"Infect Dis Clin North Am"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.mehy.2009.06.054","article-title":"The pathophysiology of the acute phase of human bartonellosis resembles AIDS","volume":"74","author":"E Ticona","year":"2010","journal-title":"Med Hypotheses"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.1996.tb08501.x","article-title":"Bartonella bacilliformis: dangerous pathogen slowly emerging from deep background","volume":"144","author":"GM Ihler","year":"1996","journal-title":"FEMS Microbiol Lett"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e2919","DOI":"10.1371\/journal.pntd.0002919","article-title":"Oroya fever and verruga peruana: bartonelloses unique to South America","volume":"8","author":"MF Minnick","year":"2014","journal-title":"PloS Negl Trop Dis"},{"key":"ref6","unstructured":"Pachas P. Epidemiologia de Bartonelosis en el Peru. Lima, Peru: Ministerio de Salud, 2000."},{"key":"ref7","unstructured":"Pachas P. Enfermedad de Carri\u00f3n (Bartonellosis) en el Per\u00fa. Lima, Peru: Ministerio de Salud. Lima, 2001."},{"key":"ref8","doi-asserted-by":"crossref","first-page":"4269","DOI":"10.1128\/JCM.38.11.4269-4271.2000","article-title":"Serodiagnosis of <italic>Bartonella bacilliformis<\/italic> infection by indirect fluorescence antibody assay: test development and application to a population in an area of Bartonellosis endemicity","volume":"8","author":"J Chamberlin","year":"2000","journal-title":"J Clin Microbiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"173","DOI":"10.4269\/ajtmh.1988.39.173","article-title":"Analysis and preparation of <italic>Bartonella bacilliformis<\/italic> antigens","volume":"39","author":"J Knobloch","year":"1988","journal-title":"Am J Trop Med Hyg"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"373","DOI":"10.4269\/ajtmh.1990.43.373","article-title":"Bb65, a major immunoreactive protein of <italic>Bartonella bacilliformis<\/italic>","volume":"43","author":"J Knobloch","year":"1990","journal-title":"Am J Trop Med Hyg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1128\/CMR.10.2.203","article-title":"Bartonella spp. as emerging human pathogens","volume":"10","author":"BE Anderson","year":"1997","journal-title":"Clin Microbiol Rev"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"4972","DOI":"10.1128\/IAI.68.9.4972-4979.2000","article-title":"Molecular cloning, sequencing, expression, and characterization of an immunogenic 43-kilodalton lipoprotein of <italic>Bartonella bacilliformis<\/italic> that has homology to NlpD\/LppB","volume":"68","author":"I Padmalayam","year":"2000","journal-title":"Infect Immun"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1196\/annals.1355.045","article-title":"Production of recombinant protein Pap31 and its application for the diagnosis of <italic>Bartonella bacilliformis<\/italic> infection","volume":"1063","author":"A Taye","year":"2005","journal-title":"Ann N Y Acad Sci"},{"key":"ref14","first-page":"695","article-title":"Situaci\u00f3n epidemiol\u00f3gica de la enfermedad de Carri\u00f3n en el Per\u00fa, SE 35\u20132014","volume":"23","author":"J Guzm\u00e1n Cuzcano","year":"2014","journal-title":"Bolet\u00edn Epidemiol\u00f3gico, Lima"},{"key":"ref15","unstructured":"Ministerio de Salud. Atenci\u00f3n de la Bartonelosis o enfermedad de Carri\u00f3n en el Per\u00fa. Norma t\u00e9cnica N\u00b0 048-MINSA\/DGSP-V.01, Lima, Peru. Ministerio de Salud, 2007."},{"key":"ref16","doi-asserted-by":"crossref","first-page":"988","DOI":"10.4269\/ajtmh.13-0246","article-title":"Dried blood spots for qPCR diagnosis of acute <italic>Bartonella bacilliformis<\/italic> infection","volume":"89","author":"PW Smit","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1128\/CVI.00717-12","article-title":"Hemin-binding proteins as potent markers for serological diagnosis of infections with <italic>Bartonella quintana<\/italic>","volume":"20","author":"M Matsuoka","year":"2013","journal-title":"Clin Vaccine Immunol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1475-2875-12-21","article-title":"Measurement of <italic>Plasmodium falciparum<\/italic> transmission intensity using serological cohort data from Indonesian schoolchildren","volume":"12","author":"MT Bretscher","year":"2013","journal-title":"Malar J"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"344","DOI":"10.4269\/ajtmh.1999.61.344","article-title":"An outbreak of acute Bartonellosis (Oroya fever) in the Urubamba region of Peru, 1998","volume":"61","author":"BA Ellis","year":"1999","journal-title":"Am J Trop Med Hyg"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1086\/322614","article-title":"Bartonellosis (Carri\u00f3n&apos;s disease) in the modern era","volume":"33","author":"C Magui\u00f1a","year":"2001","journal-title":"Clin Infect Dis"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"524","DOI":"10.3855\/jidc.6235","article-title":"An unidentified cluster of infection in the Peruvian Amazon region","volume":"9","author":"A Cornejo","year":"2015","journal-title":"J Infect Dev Ctries"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e92283","DOI":"10.1371\/journal.pone.0092283","article-title":"Diagnosis of Carrion&apos;s disease by direct blood PCR in thin blood smear negative samples","volume":"9","author":"J del Valle Mendoza","year":"2014","journal-title":"PLoS One"},{"issue":"3","key":"ref23","doi-asserted-by":"crossref","first-page":"e0004529","DOI":"10.1371\/journal.pntd.0004529","article-title":"Evaluation of PCR Approaches for Detection of <italic>Bartonella bacilliformis<\/italic> in Blood Samples","volume":"10","author":"C Gomes","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1128\/JCM.06621-11","article-title":"Development of a novel genus-specific real-time PCR assay for detection and differentiation of <italic>Bartonella<\/italic> species and genotypes","volume":"50","author":"MH Diaz","year":"2012","journal-title":"J Clin Microbiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1128\/JCM.01207-07","article-title":"Isolation and characterization of <italic>Bartonella bacilliformis<\/italic> from an expatriate Ecuadorian","volume":"46","author":"SL Lydy","year":"2008","journal-title":"J Clin Microbiol"},{"key":"ref26","first-page":"483","article-title":"An updated checklist of Phlebotomine sand flies (Diptera: Psychodidae: Phlebotominae) from the Colombian Andean coffee-growing region","volume":"34","author":"MA Contreras-Guti\u00e9rrez","year":"2014","journal-title":"Biom\u00e9dica"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1002\/elps.1150180128","article-title":"Mapping and identification of <italic>Brucella melitensis<\/italic> proteins by two-dimensional electrophoresis and microsequencing","volume":"18","author":"AP Teixeira-Gomes","year":"1997","journal-title":"Electrophoresis"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.vetmic.2010.09.033","article-title":"A comparative study of the interaction of <italic>Bartonella henselae<\/italic> strains with human endothelial cells","volume":"149","author":"CC Chang","year":"2011","journal-title":"Vet Microbiol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"6933","DOI":"10.1128\/IAI.71.12.6933-6942.2003","article-title":"Mitogenic effect of <italic>Bartonella bacilliformis<\/italic> on human vascular endothelial cells and involvement of GroEL","volume":"71","author":"MF Minnick","year":"2003","journal-title":"Infect Immun"},{"key":"ref30","first-page":"499","article-title":"Cloning, molecular analysis and epitopics prediction of a new chaperone GroEL <italic>Brucella melitensis<\/italic> antigen","volume":"18","author":"MH Sekhavati","year":"2015","journal-title":"Iran J Basic Med Sci"}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0004989","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T01:13:32Z","timestamp":1601082812000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0004989"}},"subtitle":[],"editor":[{"given":"Richard O.","family":"Phillips","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2016,9,14]]},"references-count":30,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2016,9,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0004989","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,14]]}}}