{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T20:25:24Z","timestamp":1779913524745,"version":"3.53.1"},"reference-count":10,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2016,10,20]],"date-time":"2016-10-20T00:00:00Z","timestamp":1476921600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0005023","type":"journal-article","created":{"date-parts":[[2016,10,20]],"date-time":"2016-10-20T14:03:59Z","timestamp":1476972239000},"page":"e0005023","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":31,"title":["OpenZika: An IBM World Community Grid Project to Accelerate Zika Virus Drug Discovery"],"prefix":"10.1371","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5691-5790","authenticated-orcid":false,"given":"Sean","family":"Ekins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander L.","family":"Perryman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Horta Andrade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,10,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1126\/science.aaf5036","article-title":"Zika virus in the Americas: Early epidemiological and genetic findings","volume":"352","author":"NR Faria","year":"2016","journal-title":"Science"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"150","DOI":"10.12688\/f1000research.8013.1","article-title":"Open drug discovery for the Zika virus","volume":"5","author":"S Ekins","year":"2016","journal-title":"F1000Res"},{"key":"ref3","unstructured":"Anon. WHO Director-General summarizes the outcome of the Emergency Committee regarding clusters of microcephaly and Guillain-Barr\u00e9 syndrome. 2016. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/who.int\/mediacentre\/news\/statements\/2016\/emergency-committee-zika-microcephaly\/en\/\" xlink:type=\"simple\">http:\/\/who.int\/mediacentre\/news\/statements\/2016\/emergency-committee-zika-microcephaly\/en\/<\/ext-link>."},{"key":"ref4","article-title":"Zika Virus: Diagnosis, Therapeutics, and Vaccine","author":"C Shan","year":"2016","journal-title":"ACS Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e0004530","DOI":"10.1371\/journal.pntd.0004530","article-title":"Zika Virus: Medical Countermeasure Development Challenges","volume":"10","author":"RW Malone","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"275","DOI":"10.12688\/f1000research.8213.2","article-title":"Illustrating and homology modeling the proteins of the Zika virus","volume":"5","author":"S Ekins","year":"2016","journal-title":"F1000Res"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1126\/science.aaf5316","article-title":"The 3.8 A resolution cryo-EM structure of Zika virus","volume":"352","author":"D Sirohi","year":"2016","journal-title":"Science"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1021\/acschembio.5b00370","article-title":"Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents","volume":"10","author":"VA Kincaid","year":"2015","journal-title":"ACS Chem Biol"},{"key":"ref9","unstructured":"Text of the Adding Zika Virus to the FDA Priority Review Voucher Program Act. 2016. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.govtrack.us\/congress\/bills\/114\/s2512\/text\" xlink:type=\"simple\">https:\/\/www.govtrack.us\/congress\/bills\/114\/s2512\/text<\/ext-link>."},{"key":"ref10","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s11095-015-1841-9","article-title":"Incentives for Starting Small Companies Focused on Rare and Neglected Diseases","volume":"33","author":"S Ekins","year":"2016","journal-title":"Pharm Res"}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0005023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T17:51:46Z","timestamp":1588960306000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0005023"}},"subtitle":[],"editor":[{"given":"David Joseph","family":"Diemert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,10,20]]},"references-count":10,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2016,10,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0005023","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,20]]}}}