{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:56:58Z","timestamp":1787021818794,"version":"build-2736575974"},"update-to":[{"DOI":"10.1371\/journal.pntd.0005217","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T00:00:00Z","timestamp":1482364800000}}],"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T00:00:00Z","timestamp":1481500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007001","name":"Small Business Innovative Research and Small Business Technology Transfer","doi-asserted-by":"publisher","award":["R42AI102482"],"award-info":[{"award-number":["R42AI102482"]}],"id":[{"id":"10.13039\/100007001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0005217","type":"journal-article","created":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T16:55:30Z","timestamp":1481561730000},"page":"e0005217","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["In vivo Distribution and Clearance of Purified Capsular Polysaccharide from Burkholderia pseudomallei in a Murine Model"],"prefix":"10.1371","volume":"10","author":[{"given":"Teerapat","family":"Nualnoi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Kirosingh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata G.","family":"Pandit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Thorkildson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Brett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary N.","family":"Burtnick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"AuCoin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2016,12,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1056\/NEJMra1204699","article-title":"Medical Progress Melioidosis","volume":"367","author":"JW Wiersinga","year":"2012","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"15008","DOI":"10.1038\/nmicrobiol.2015.8","article-title":"Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis","volume":"1","author":"D Limmathurotsakul","year":"2016","journal-title":"Nat Microbiol. Nature Publishing Group"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1177\/0897190012456366","article-title":"Bioterrorism: pathogens as weapons","volume":"25","author":"PD Anderson","year":"2012","journal-title":"J Pharm Pract"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3201\/eid0802.010164","article-title":"Public health assessment of potential biological terrorism agents","volume":"8","author":"LD Rotz","year":"2002","journal-title":"Emerg Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/490456a","article-title":"Viral research faces clampdown","volume":"490","author":"D Butler","year":"2012","journal-title":"Nature"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1055\/s-0034-1398389","article-title":"Melioidosis: evolving concepts in epidemiology, pathogenesis, and treatment","volume":"36","author":"BJ Currie","year":"2015","journal-title":"Semin Respir Crit Care Med. Thieme Medical Publishers"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"e12485","DOI":"10.1371\/journal.pone.0012485","article-title":"Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian Latent Class models","volume":"5","author":"D Limmathurotsakul","year":"2010","journal-title":"PLoS One"},{"key":"ref8","first-page":"e141045","article-title":"Melioidosis diagnostic workshop, 2013","volume":"21","author":"AR Hoffmaster","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1099\/jmm.0.000098","article-title":"Rapid diagnostics for melioidosis: a comparative study of a novel lateral flow antigen detection assay","volume":"64","author":"G Robertson","year":"2015","journal-title":"J Med Microbiol. Microbiology Society"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e2727","DOI":"10.1371\/journal.pntd.0002727","article-title":"Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis","volume":"8","author":"RL Houghton","year":"2014","journal-title":"PLoS Negl Trop Dis. Public Library of Science"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.1128\/IAI.63.9.3348-3352.1995","article-title":"Structural characterization of the lipopolysaccharide O antigens of Burkholderia pseudomallei","volume":"63","author":"MB Perry","year":"1995","journal-title":"Infect Immun"},{"key":"ref12","first-page":"108","article-title":"Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders","volume":"2","author":"MN Burtnick","year":"2012","journal-title":"Front Cell Infect Microbiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"e35386","DOI":"10.1371\/journal.pone.0035386","article-title":"Polysaccharide specific monoclonal antibodies provide passive protection against intranasal challenge with Burkholderia pseudomallei","volume":"7","author":"DP AuCoin","year":"2012","journal-title":"PLoS One. Public Library of Science"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"e1488","DOI":"10.1371\/journal.pntd.0001488","article-title":"Melioidosis vaccines: A systematic review and appraisal of the potential to exploit biodefense vaccines for public health purposes","volume":"6","author":"SJ Peacock","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"ref15","first-page":"e00136","article-title":"Identification of circulating bacterial antigens by in vivo microbial antigen discovery","volume":"2","author":"DE Nuti","year":"2011","journal-title":"MBio"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1128\/IAI.01176-07","article-title":"In vivo fate and distribution of poly-gamma-D-glutamic acid, the capsular antigen from Bacillus anthracis","volume":"76","author":"MD Sutherland","year":"2008","journal-title":"Infect Immun"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1021\/acschembio.5b00502","article-title":"Burkholderia pseudomallei capsular polysaccharide recognition by a monoclonal antibody reveals key details toward a biodefense vaccine and diagnostics against melioidosis","volume":"10","author":"R Marchetti","year":"2015","journal-title":"ACS Chem Biol. American Chemical Society"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1152\/ajplegacy.1959.196.2.420","article-title":"Circulating and tissue hematocrits of normal unanesthetized mice","volume":"196","author":"JJ Friedman","year":"1959","journal-title":"Am J Physiol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1086\/322787","article-title":"In vivo clearance of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans: a critical role for tissue macrophages","volume":"184","author":"M Grinsell","year":"2001","journal-title":"J Infect Dis. Oxford University Press"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"5042","DOI":"10.1073\/pnas.0401351101","article-title":"mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia","volume":"101","author":"TR Kozel","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1128\/JCM.29.8.1616-1619.1991","article-title":"Comparison of the PREMIER cryptococcal antigen enzyme immunoassay and the latex agglutination assay for detection of cryptococcal antigens","volume":"29","author":"W Gade","year":"1991","journal-title":"J Clin Microbiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1542\/peds.78.1.1","article-title":"Use of bacterial antigen detection in the diagnosis of pediatric lower respiratory tract infections","volume":"78","author":"BW Ramsey","year":"1986","journal-title":"Pediatrics"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"971","DOI":"10.4269\/ajtmh.13-0212","article-title":"Rapid detection of Burkholderia pseudomallei in blood cultures using a monoclonal antibody-based immunofluorescent assay","volume":"89","author":"N Chantratita","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1128\/IAI.62.5.1507-1512.1994","article-title":"Polysaccharide antigens of the capsule of Cryptococcus neoformans","volume":"62","author":"R Cherniak","year":"1994","journal-title":"Infect Immun"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1046\/j.1365-2672.1999.00881.x","article-title":"The capsule of bacillus anthracis, a review","volume":"87","author":"J Ezzell","year":"1999","journal-title":"J Appl Microbiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0141-8130(98)00047-6","article-title":"On the helical conformation of un-ionized poly(\u03b3-d-glutamic acid)","volume":"23","author":"D Zanuy","year":"1998","journal-title":"Int J Biol Macromol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1084\/jem.91.1.15","article-title":"Localization of antigen in tissue cells; cellular distribution of pneumococcal polysaccharides types II and III in the mouse","volume":"91","author":"MH Kaplan","year":"1950","journal-title":"J Exp Med"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3109\/00365516809076979","article-title":"The glomerular permeability determined by dextran clearance using Sephadex gel filtration","volume":"21","author":"CE Mogensen","year":"1968","journal-title":"Scand J Clin Lab Invest"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"12369","DOI":"10.1073\/pnas.0913667107","article-title":"Paradoxical glomerular filtration of carbon nanotubes","volume":"107","author":"A Ruggiero","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1086\/515329","article-title":"Effect of immune mechanisms on the pharmacokinetics and organ distribution of cyptococcal polysaccharide","volume":"177","author":"N Lendvai","year":"1998","journal-title":"J Infect Dis"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0005217","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T00:00:00Z","timestamp":1482364800000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0005217","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,16]],"date-time":"2022-07-16T19:30:01Z","timestamp":1657999801000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0005217"}},"subtitle":[],"editor":[{"given":"Christian","family":"Johnson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2016,12,12]]},"references-count":30,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2016,12,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0005217","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,12]]}}}