{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:34:25Z","timestamp":1790519665950,"version":"4.1.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0005487","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T00:00:00Z","timestamp":1491350400000}}],"reference-count":70,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T00:00:00Z","timestamp":1490313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0005487","type":"journal-article","created":{"date-parts":[[2017,3,24]],"date-time":"2017-03-24T13:25:29Z","timestamp":1490361929000},"page":"e0005487","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":27,"title":["Vector status of Aedes species determines geographical risk of autochthonous Zika virus establishment"],"prefix":"10.1371","volume":"11","author":[{"given":"Lauren","family":"Gardner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahotra","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,3,24]]},"reference":[{"key":"ref1","unstructured":"PAHO. Zika cases and congenital syndrome associated with Zika virus reported by countries and territories in the Americas, 2015\u20132016 Cumulative Cases. [Web Page]. Washington DC: World Health Organization, Pan American Health Organization; 2016. Available from: http:\/\/www.paho.org\/hq\/index.php?option=com_docman&task=doc_view&Itemid=270&gid=37495&lang=en<\/ext-link>."},{"key":"ref2","unstructured":"World Health Organization (WHO). WHO Situation Report: Zika Virus, Microcephaly and Guillain-Barre Syndrome [Web Page]; 2016. Available from: http:\/\/apps.who.int\/iris\/bitstream\/10665\/204454\/1\/zikasitrep_19Feb2016_eng.pdf?ua=1<\/ext-link>."},{"key":"ref3","unstructured":"Centers for Disease Control and Prevention (CDC). Areas with Zika [Web Page]; 2016. Available from: http:\/\/www.cdc.gov\/zika\/geo\/<\/ext-link>."},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/0035-9203(77)90104-3","article-title":"A yellow fever epizootic in Zika Forest, Uganda, during 1972: Part 2: Monkey serology","volume":"71","author":"BG Kirya","year":"1977","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"5","key":"ref5","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0035-9203(52)90043-6","article-title":"Zika virus (II). Pathogenicity and physical properties","volume":"46","author":"GWA Dick","year":"1952","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"24","key":"ref6","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1056\/NEJMoa0805715","article-title":"Zika Virus Outbreak on Yap Island, Federated States of Micronesia","volume":"360","author":"MR Duffy","year":"2009","journal-title":"New England Journal of Medicine"},{"issue":"8","key":"ref7","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.3201\/eid1408.080287","article-title":"Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007","volume":"14","author":"RS Lanciotti","year":"2008","journal-title":"Emerg Infect Dis"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","DOI":"10.3201\/eid2205.160065","article-title":"Phylogeny of Zika virus in Western Hemisphere","volume":"22","author":"R Lanciotti","year":"2015","journal-title":"Emerg Infect Dis"},{"issue":"7","key":"ref9","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.medmal.2014.04.008","article-title":"Current Zika virus epidemiology and recent epidemics","volume":"44","author":"S Ioos","year":"2014","journal-title":"Medecine et Maladies Infectieuses"},{"issue":"8","key":"ref10","doi-asserted-by":"crossref","DOI":"10.3201\/eid2008.140302","article-title":"Zika virus infection after travel to Tahiti, December 2013","volume":"20","author":"T W\u00e6hre","year":"2013","journal-title":"Emerg Infect Dis"},{"issue":"4","key":"ref11","article-title":"Two cases of Zika fever imported from French Polynesia to Japan, December 2013 to January 2014","volume":"18","author":"S Kutsuna","year":"2014","journal-title":"Euro Surveillance"},{"issue":"4","key":"ref12","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES2014.19.4.20685","article-title":"First case of laboratory-confirmed Zika virus infection imported into Europe, November 2013","volume":"19","author":"D Tappe","year":"2014","journal-title":"Euro Surveill"},{"issue":"3","key":"ref13","doi-asserted-by":"crossref","first-page":"55","DOI":"10.15585\/mmwr.mm6503e1","article-title":"Zika Virus Spreads to New Areas\u2014Region of the Americas, May 2015-January 2016","volume":"65","author":"M Hennessey","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref14","article-title":"Zika virus in the Americas: Early epidemiological and genetic findings","author":"N Faria","year":"2016","journal-title":"Science"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.15585\/mmwr.mm6503e2","article-title":"Possible Association Between Zika Virus Infection and Microcephaly\u2014Brazil, 2015","volume":"65","author":"L Schuler-Faccini","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"1","key":"ref16","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/uog.15831","article-title":"Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: Tip of the iceberg?","volume":"47","author":"AS Oliveira Melo","year":"2016","journal-title":"Ultrasound in Obstetrics and Gynecology"},{"issue":"13","key":"ref17","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES2014.19.13.20751","article-title":"Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014","volume":"19","author":"M Besnard","year":"2014","journal-title":"Euro Surveill"},{"key":"ref18","unstructured":"PAHO. Epidemiological alert. Increase in microcephaly in the northeast of Brazil\u2014epidemiological alert. [Web Page]. Washington DC: World Health Organization, Pan American Health Organization; 2015. Available from: http:\/\/www.paho.org\/hq\/index.php?option=com_docman&task=doc_view&Itemid=270&gid=32636&lang=en<\/ext-link>."},{"key":"ref19","article-title":"Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities","author":"RW Driggers","journal-title":"New England Journal of Medicine"},{"key":"ref20","article-title":"Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells","author":"TJ Nowakowski","year":"2016","journal-title":"Cell Stem Cell"},{"issue":"13","key":"ref21","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2016.21.13.30181","article-title":"Congenital Cerebral Malformations And Dysfunction In Fetuses And Newborns Following The 2013 To 2014 Zika Virus Epidemic In French Polynesia","volume":"21","author":"M Besnard","year":"2016","journal-title":"Euro Surveill"},{"key":"ref22","unstructured":"World Health Organization (WHO). WHO Situation Report: Zika Virus, Microcephaly and Guillain-Barre Syndrome [Web Page]; 2016. Available from: http:\/\/apps.who.int\/iris\/bitstream\/10665\/204961\/1\/zikasitrep_7Apr2016_eng.pdf?ua=1<\/ext-link>."},{"issue":"9","key":"ref23","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES2014.19.9.20720","article-title":"Zika virus infection complicated by Guillain-Barre syndrome\u2013case report, French Polynesia, December 2013","volume":"19","author":"E Oehler","year":"2014","journal-title":"Euro Surveill"},{"key":"ref24","unstructured":"World Health Organization (WHO). WHO statement on the first meeting of the International Health Regulations (2005) (IHR 2005) Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations [Web Page]; 2016. Available from: http:\/\/www.who.int\/mediacentre\/news\/statements\/2016\/1st-emergency-committee-zika\/en\/<\/ext-link>."},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/j.mcna.2008.07.002","article-title":"Geographic Expansion of Dengue: The Impact of International Travel","volume":"92","author":"A Wilder-Smith","year":"2008","journal-title":"Medical Clinics of North America"},{"issue":"8","key":"ref26","doi-asserted-by":"crossref","first-page":"e1792","DOI":"10.1371\/journal.pntd.0001792","article-title":"Oral susceptibility of Singapore Aedes (Stegomyia) aegypti (Linnaeus) to Zika virus","volume":"6","author":"MI Li","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"492","key":"ref27","article-title":"Potential of selected Senegalese Aedes spp. mosquitoes (Diptera: Culicidae) to transmit Zika virus","volume":"15","author":"CT Diagne","year":"2015","journal-title":"BMC Infect Dis"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/0035-9203(56)90029-3","article-title":"A simple technique for infection of mosquitoes with viruses transmission of zika virus","volume":"50","author":"JPT Boorman","year":"1956","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"ref29","article-title":"Outbreak of Zika virus infection, Chiapas State, Mexico, 2015, and first confirmed transmission by Aedes aegypti mosquitoes in the Americas","author":"M Guerbois","year":"2016","journal-title":"Journal of Infectious Diseases (Advance Access)"},{"key":"ref30","unstructured":"World Health Organization (WHO). Zika Virus Technical Report. Interim Risk Assessment WHO European Region [Web Page]; 2016. Available from: http:\/\/www.euro.who.int\/__data\/assets\/pdf_file\/0003\/309981\/Zika-Virus-Technical-report.pdf<\/ext-link>."},{"key":"ref31","unstructured":"World Health Organization (WHO). Zika virus vectors and risk of spread in the WHO European Region [Web Page]; 2016. Available from: http:\/\/www.euro.who.int\/__data\/assets\/pdf_file\/0007\/304459\/WEB-news_competence-of-Aedes-aegypti-and-albopictus-vector-species.pdf<\/ext-link>."},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0035-9203(81)90100-0","article-title":"Zika virus, a cause of fever in Central Java, Indonesia","volume":"75","author":"JG Olson","year":"1981","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"2","key":"ref33","doi-asserted-by":"crossref","first-page":"e2681","DOI":"10.1371\/journal.pntd.0002681","article-title":"Zika virus in Gabon (Central Africa)\u20132007: a new threat from Aedes albopictus?","volume":"8","author":"G Grard","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"issue":"8","key":"ref34","doi-asserted-by":"crossref","first-page":"e2348","DOI":"10.1371\/journal.pntd.0002348","article-title":"Aedes (Stegomyia) albopictus (Skuse): a potential vector of Zika virus in Singapore","volume":"7","author":"PS Wong","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"ref35","article-title":"Zika virus, a new threat for Europe?","author":"H Jupille","year":"2016","journal-title":"bioRxiv"},{"issue":"3","key":"ref36","doi-asserted-by":"crossref","first-page":"e0004543","DOI":"10.1371\/journal.pntd.0004543","article-title":"Differential Susceptibilities of Aedes aegypti and Aedes albopictus from the Americas to Zika Virus","volume":"10","author":"T Chouin-Carneiro","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"e201","key":"ref37","article-title":"A single mutation in chikungunya virus affects vector specificity and epidemic potential","volume":"3","author":"K Tsetsarkin","year":"2007","journal-title":"PLoS Pathog"},{"issue":"e1168","key":"ref38","article-title":"Two Chikungunya isolates from the outbreak of La Reunion (Indian Ocean) exhibit different patterns of infection in the mosquito, Aedes albopictus","volume":"2","author":"M Vazeille","year":"2007","journal-title":"PLoS One"},{"key":"ref39","article-title":"Global risk of Zika virus depends critically on vector status of Aedes albopictus","author":"L Gardner","year":"2016","journal-title":"The Lancet Infectious Diseases"},{"key":"ref40","article-title":"Anticipating the international spread of Zika virus from Brazil","author":"II Bogoch","year":"2015","journal-title":"The Lancet"},{"issue":"11","key":"ref41","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1016\/S1473-3099(16)30270-5","article-title":"Potential for Zika virus introduction and transmission in resource-limited countries in Africa and the Asia-Pacific region: a modelling study","volume":"16","author":"II Bogoch","year":"2016","journal-title":"The Lancet Infectious Diseases"},{"key":"ref42","article-title":"On the Seasonal Occurrence and Abundance of the Zika Virus Vector Mosquito Aedes Aegypti in the Contiguous United States","author":"A Monaghan","year":"2016","journal-title":"PLOS Currents Outbreaks"},{"issue":"e1904","key":"ref43","article-title":"Estimating risks of importation and local transmission of Zika virus infection","volume":"4","author":"K Nah","year":"2016","journal-title":"PeerJ"},{"key":"ref44","unstructured":"MoH. Ministry of Health Singapore: Zika; 2016. Available from: https:\/\/www.moh.gov.sg\/content\/moh_web\/home\/diseases_and_conditions\/z\/zika.html<\/ext-link>."},{"key":"ref45","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/103679","article-title":"A Predictive Spatial Model to Quantify the Risk of Air-Travel-Associated Dengue Importation into the United States and Europe","volume":"2012","author":"L Gardner","year":"2012","journal-title":"Journal of tropical medicine"},{"issue":"8","key":"ref46","doi-asserted-by":"crossref","first-page":"e72129","DOI":"10.1371\/journal.pone.0072129","article-title":"A Global Airport-Based Risk Model for the Spread of Dengue Infection via the Air Transport Network","volume":"8","author":"L Gardner","year":"2013","journal-title":"PloS one"},{"issue":"2501","key":"ref47","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3141\/2501-04","article-title":"Risk of dengue spread from the Philippines through international air travel","volume":"2501","author":"L Gardner","year":"2015","journal-title":"Transportation Research Record: Journal of the Transportation Research Board"},{"issue":"1","key":"ref48","doi-asserted-by":"crossref","first-page":"e585","DOI":"10.1371\/journal.pntd.0000585","article-title":"Climate Change and Risk of Leishmaniasis in North America: Predictions from Ecological Niche Models of Vector and Reservoir Species","volume":"4","author":"C Gonz\u00e1lez","year":"2010","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"9","key":"ref49","doi-asserted-by":"crossref","first-page":"e824","DOI":"10.1371\/journal.pone.0000824","article-title":"Malaria in Africa: Vector Species\u2019 Niche Models and Relative Risk Maps","volume":"2","author":"A Moffett","year":"2007","journal-title":"PLoS ONE"},{"issue":"10","key":"ref50","doi-asserted-by":"crossref","first-page":"e836","DOI":"10.1371\/journal.pntd.0000836","article-title":"Chagas Disease Risk in Texas","volume":"4","author":"S Sarkar","year":"2010","journal-title":"PLoS Neglected Tropical Diseases"},{"key":"ref51","article-title":"Systematic Conservation Planning","author":"C Margules","year":"2007"},{"key":"ref52","article-title":"Mapping Species Distributions: Spatial Inference and Prediction","author":"F J","year":"2009"},{"issue":"3-4","key":"ref53","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.ecolmodel.2005.03.026","article-title":"Maximum entropy modeling of species geographic distributions","volume":"190","author":"SJ SR Phillips","year":"2006","journal-title":"Ecological Modelling"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.0906-7590.2008.5203.x","article-title":"Modeling of species distributions with Maxent: new extensions and a comprehensive evaluation","volume":"31","author":"SJ Phillips","year":"2008","journal-title":"Ecography"},{"issue":"1665","key":"ref55","doi-asserted-by":"crossref","DOI":"10.1098\/rstb.2014.0135","article-title":"Climate change influences on global distributions of dengue and chikungunya virus vectors","volume":"370","author":"LP Campbell","year":"2015","journal-title":"Philosophical Transactions of the Royal Society of London B: Biological Sciences"},{"key":"ref56","article-title":"The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus","author":"MU Kraemer","year":"2015","journal-title":"eLIFE"},{"key":"ref57","article-title":"Mapping global environmental suitability for Zika virus","author":"JP Messina","year":"2016","journal-title":"eLIFE"},{"key":"ref58","unstructured":"IATA. Air Passenger Market Analysis December 2015 [Web Page]; 2016. Available from: http:\/\/www.iata.org\/whatwedo\/Documents\/economics\/passenger-analysis-dec-2015.pdf<\/ext-link>."},{"issue":"3","key":"ref59","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/S1473-3099(16)00073-6","article-title":"Identification of Zika virus vectors and implications for control","volume":"16","author":"CFJ Ayres","year":"2016","journal-title":"The Lancet Infectious Diseases"},{"key":"ref60","article-title":"Culex pipiens and Aedes triseriatus mosquito susceptibility to Zika virus","author":"M Aliota","year":"2016","journal-title":"Emerg Infect Dis"},{"issue":"5","key":"ref61","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3201\/eid1705.101939","article-title":"Probable non-vector-borne transmission of Zika virus, Colorado, USA","volume":"17","author":"BD Foy","year":"2011","journal-title":"Emerg Infect Dis"},{"issue":"2","key":"ref62","doi-asserted-by":"crossref","first-page":"359","DOI":"10.3201\/eid2102.141363","article-title":"Potential sexual transmission of Zika virus","volume":"21","author":"D Musso","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"ref63","article-title":"Transmission of Zika Virus Through Sexual Contact with Travelers to Areas of Ongoing Transmission\u2014Continental United States","author":"S Hills","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jcv.2015.04.021","article-title":"Detection of Zika virus in saliva","volume":"68","author":"D Musso","year":"2015","journal-title":"J Clin Virol"},{"issue":"1","key":"ref65","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3201\/eid2101.140894","article-title":"Detection of Zika virus in urine","volume":"21","author":"AC Gourinat","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"ref66","article-title":"Zika Virus in the Americas\u2014Yet Another Arbovirus Threat","author":"AS Fauci","year":"2016","journal-title":"N Engl J Med"},{"issue":"1","key":"ref67","doi-asserted-by":"crossref","first-page":"73","DOI":"10.7589\/0090-3558-39.1.73","article-title":"Health evaluation of free-ranging and semi-captive orangutans (Pongo pygmaeus pygmaeus) in Sabah, Malaysia","volume":"39","author":"AM Kilbourn","year":"2003","journal-title":"J Wildl Dis"},{"issue":"2","key":"ref68","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1017\/S0022172400025997","article-title":"Zika virus infections in Nigeria: virological and seroepidemiological investigations in Oyo State","volume":"83","author":"AH Fagbami","year":"1979","journal-title":"J Hyg (Lond)"},{"issue":"4","key":"ref69","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/0035-9203(83)90106-2","article-title":"A sero-epidemiological survey for certain arboviruses (Togaviridae) in Pakistan","volume":"77","author":"MA Darwish","year":"1983","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"issue":"5-6","key":"ref70","doi-asserted-by":"crossref","first-page":"310","DOI":"10.4269\/ajtmh.2001.64.310","article-title":"Sylvatic transmission of arboviruses among Bornean orangutans","volume":"64","author":"ND Wolfe","year":"2001","journal-title":"Am J Trop Med Hyg"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0005487","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T00:00:00Z","timestamp":1491350400000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0005487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T01:10:33Z","timestamp":1568941833000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0005487"}},"subtitle":[],"editor":[{"given":"Donald S","family":"Shepard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,3,24]]},"references-count":70,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,3,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0005487","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pntd.0005487","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3,24]]}}}