{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T08:29:32Z","timestamp":1785659372041,"version":"3.56.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0005700","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T00:00:00Z","timestamp":1501459200000}}],"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T00:00:00Z","timestamp":1500422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"International Medical Corps"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0005700","type":"journal-article","created":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T17:35:08Z","timestamp":1500485708000},"page":"e0005700","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["The natural history of acute Ebola Virus Disease among patients managed in five Ebola treatment units in West Africa: A retrospective cohort study"],"prefix":"10.1371","volume":"11","author":[{"given":"Kelly","family":"Skrable","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reshma","family":"Roshania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Mallow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Wolfman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Siakor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3982-3824","authenticated-orcid":true,"given":"Adam C.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,7,19]]},"reference":[{"issue":"16","key":"ref1","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1056\/NEJMoa1411100","article-title":"Ebola virus disease in West Africa\u2014the first 9 months of the epidemic and forward projections","volume":"371","year":"2014","journal-title":"N Engl J Med"},{"key":"ref2","unstructured":"WHO. Ebola Situation Report\u201430 March 2016 2016 [cited 2016 April 5, 2016]. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/apps.who.int\/ebola\/current-situation\/ebola-situation-report-30-march-2016\" xlink:type=\"simple\">http:\/\/apps.who.int\/ebola\/current-situation\/ebola-situation-report-30-march-2016<\/ext-link>."},{"issue":"15","key":"ref3","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1056\/NEJMoa1404505","article-title":"Emergence of Zaire Ebola virus disease in Guinea","volume":"371","author":"S Baize","year":"2014","journal-title":"N Engl J Med"},{"issue":"4","key":"ref4","doi-asserted-by":"crossref","first-page":"28406","DOI":"10.3402\/jchimp.v5.28406","article-title":"Association of clinical signs and symptoms of Ebola viral disease with case fatality: a systematic review and meta-analysis","volume":"5","author":"H Moole","year":"2015","journal-title":"J Community Hosp Intern Med Perspect"},{"issue":"4","key":"ref5","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1093\/cid\/civ319","article-title":"Clinical Features of Patients With Ebola Virus Disease in Sierra Leone","volume":"61","author":"E Qin","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"11","key":"ref6","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.3201\/eid2111.150582","article-title":"Ebola Virus Outbreak Investigation, Sierra Leone, September 28-November 11, 2014","volume":"21","author":"HJ Lu","year":"2015","journal-title":"Emerg Infect Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ijid.2015.10.021","article-title":"Age and Ebola viral load correlate with mortality and survival time in 288 Ebola virus disease patients","volume":"42","author":"J Li","year":"2016","journal-title":"Int J Infect Dis"},{"issue":"9","key":"ref8","doi-asserted-by":"crossref","first-page":"e0004113","DOI":"10.1371\/journal.pntd.0004113","article-title":"Prognostic Analysis of Patients with Ebola Virus Disease","volume":"9","author":"X Zhang","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1056\/NEJMoa1411249","article-title":"Clinical presentation of patients with Ebola virus disease in Conakry, Guinea","volume":"372","author":"EI Bah","year":"2015","journal-title":"N Engl J Med"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1093\/cid\/civ202","article-title":"Clinical predictors of mortality in patients with Ebola virus disease","volume":"60","author":"M Barry","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"11","key":"ref11","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1093\/infdis\/jiv304","article-title":"The Contribution of Ebola Viral Load at Admission and Other Patient Characteristics to Mortality in a M\u00e9decins Sans Fronti\u00e8res Ebola Case Management Centre, Kailahun, Sierra Leone, June-October 2014","volume":"212","author":"G Fitzpatrick","year":"2015","journal-title":"J Infect Dis"},{"issue":"2","key":"ref12","doi-asserted-by":"crossref","first-page":"217","DOI":"10.3201\/eid2202.151250","article-title":"Prognostic Indicators for Ebola Patient Survival","volume":"22","author":"SJ Crowe","year":"2016","journal-title":"Emerg Infect Dis"},{"issue":"11","key":"ref13","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1016\/S1473-3099(15)00144-9","article-title":"Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort study","volume":"15","author":"L Hunt","year":"2015","journal-title":"Lancet Infect Dis"},{"key":"ref14","article-title":"Implementation of a multi-country Ebola Virus Disease clinical surveillance and data collection system in West Africa: Lessons from the field","author":"R Roshania","year":"2015","journal-title":"Global Health: Science and Practice"},{"key":"ref15","article-title":"Handbook: Integrated Management of Childhood Illness (IMCI)"},{"issue":"10","key":"ref16","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.apjtm.2015.09.001","article-title":"Is there a way out for the 2014 Ebola outbreak in Western Africa?","volume":"8","author":"A Andreas","year":"2015","journal-title":"Asian Pac J Trop Med"},{"issue":"11\u201312","key":"ref17","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.medmal.2014.09.009","article-title":"Ebola outbreak in Conakry, Guinea: epidemiological, clinical, and outcome features","volume":"44","author":"M Barry","year":"2014","journal-title":"Med Mal Infect"},{"issue":"22","key":"ref18","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1056\/NEJMp1413084","article-title":"Ebola virus disease in West Africa\u2014clinical manifestations and management","volume":"371","author":"DS Chertow","year":"2014","journal-title":"N Engl J Med"},{"issue":"8","key":"ref19","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.ajic.2015.05.005","article-title":"Ebola virus disease: What clinicians in the United States need to know","volume":"43","author":"WA Fischer 2nd","year":"2015","journal-title":"Am J Infect Control"},{"issue":"9","key":"ref20","first-page":"442","article-title":"Ebola virus disease: a review on epidemiology, symptoms, treatment and pathogenesis","volume":"72","author":"M Goeijenbier","year":"2014","journal-title":"Neth J Med"},{"issue":"6","key":"ref21","doi-asserted-by":"crossref","first-page":"e0129333","DOI":"10.1371\/journal.pone.0129333","article-title":"Ebola Virus Disease Outbreak in Isiro, Democratic Republic of the Congo, 2012: Signs and Symptoms, Management and Outcomes","volume":"10","author":"T Kratz","year":"2015","journal-title":"PLoS One"},{"issue":"1","key":"ref22","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.annemergmed.2014.10.009","article-title":"Ebola virus outbreak 2014: clinical review for emergency physicians","volume":"65","author":"L Meyers","year":"2015","journal-title":"Ann Emerg Med"},{"issue":"7","key":"ref23","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1056\/NEJMoa1504874","article-title":"Clinical Management of Ebola Virus Disease in the United States and Europe","volume":"374","author":"TM Uyeki","year":"2016","journal-title":"N Engl J Med"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1093\/cid\/civ568","article-title":"Epidemiology and risk factors for Ebola virus disease in Sierra Leone-23 May 2014 to 31 January 2015","volume":"61","author":"PM Dietz","year":"2015","journal-title":"Clin Infect Dis"},{"key":"ref25","article-title":"Characteristics and survival of patients with Ebola virus infection, malaria, or both in Sierra Leone: a retrospective cohort study","author":"M Waxman","year":"2017","journal-title":"Lancet Infect Dis"},{"issue":"12","key":"ref26","doi-asserted-by":"crossref","first-page":"4692","DOI":"10.1172\/JCI83111","article-title":"Blood kinetics of Ebola virus in survivors and nonsurvivors","volume":"125","author":"S Lanini","year":"2015","journal-title":"J Clin Invest"},{"issue":"8","key":"ref27","doi-asserted-by":"crossref","first-page":"4330","DOI":"10.1128\/JVI.78.8.4330-4341.2004","article-title":"Rapid diagnosis of Ebola hemorrhagic fever by reverse transcription-PCR in an outbreak setting and assessment of patient viral load as a predictor of outcome","volume":"78","author":"JS Towner","year":"2004","journal-title":"J Virol"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/cid\/ciw725","article-title":"Characteristics and Outcomes of Pediatric Patients With Ebola Virus Disease Admitted to Treatment Units in Liberia and Sierra Leone: A Retrospective Cohort Study","volume":"64","author":"MA Smit","year":"2017","journal-title":"Clin Infect Dis"},{"issue":"15","key":"ref29","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1056\/NEJMoa1604330","article-title":"A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection","volume":"375","year":"2016","journal-title":"N Engl J Med"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0005700","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,7,31]],"date-time":"2017-07-31T00:00:00Z","timestamp":1501459200000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0005700","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T16:15:45Z","timestamp":1750781745000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0005700"}},"subtitle":[],"editor":[{"given":"Johan","family":"van Griensven","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,7,19]]},"references-count":29,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2017,7,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0005700","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pntd.0005700","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,19]]}}}