{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T10:24:59Z","timestamp":1787826299574,"version":"build-2784847793"},"update-to":[{"DOI":"10.1371\/journal.pntd.0005758","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000}}],"reference-count":10,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T00:00:00Z","timestamp":1500508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Mega-Project for National Science and Technology Development under the \u201c12th, Five-Year Plan of China\u201d","award":["2013ZX10004-904"],"award-info":[{"award-number":["2013ZX10004-904"]}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0005758","type":"journal-article","created":{"date-parts":[[2017,7,20]],"date-time":"2017-07-20T13:38:25Z","timestamp":1500557905000},"page":"e0005758","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["The tradition algorithm approach underestimates the prevalence of serodiagnosis of syphilis in HIV-infected individuals"],"prefix":"10.1371","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1553-2803","authenticated-orcid":true,"given":"Bin","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuming","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiansheng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changzhong","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2017,7,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1111\/jdv.12734","article-title":"2014 European guideline on the management of syphilis","volume":"28","author":"M Janier","year":"2014","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1128\/CVI.00681-14","article-title":"Recent trends in the serologic diagnosis of syphilis","volume":"22","author":"MG Morshed","year":"2015","journal-title":"Clinical and vaccine immunology: CVI"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/978-81-322-1774-9_5","article-title":"Current trend on syphilis diagnosis: issues and challenges","volume":"808","author":"MG Morshed","year":"2014","journal-title":"Adv Exp Med Biol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1556\/AMicr.60.2013.2.2","article-title":"Syphilis in the AIDS era: diagnostic dilemma and therapeutic challenge","volume":"60","author":"JB Scythes","year":"2013","journal-title":"Acta Microbiol Immunol Hung"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/DAD.0b013e3181e8b587","article-title":"The immunopathobiology of syphilis: the manifestations and course of syphilis are determined by the level of delayed-type hypersensitivity","volume":"33","author":"JA Carlson","year":"2011","journal-title":"The American Journal of dermatopathology"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1186\/s12879-014-0658-1","article-title":"Risk factors associated with prevalent and incident syphilis among an HIV-infected cohort","volume":"14","author":"QH Hu","year":"2014","journal-title":"Northeast China. BMC Infect Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1128\/JCM.05636-11","article-title":"Direct comparison of the traditional and reverse syphilis screening algorithms in a population with a low prevalence of syphilis","volume":"50","author":"MJ Binnicker","year":"2012","journal-title":"J Clin Microbiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1093\/cid\/ciu087","article-title":"Analysis of 3 algorithms for syphilis serodiagnosis and implications for clinical management","volume":"58","author":"ML Tong","year":"2014","journal-title":"Clinical infectious diseases: an official publication of the Infectious Diseases Society of America"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/QCO.0b013e32834e9a3c","article-title":"Which algorithm should be used to screen for syphilis?","volume":"25","author":"MJ Binnicker","year":"2012","journal-title":"Curr Opin Infect Dis"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.meegid.2011.12.001","article-title":"Genetic diversity in Treponema pallidum: implications for pathogenesis, evolution and molecular diagnostics of syphilis and yaws","volume":"12","author":"D Smajs","year":"2012","journal-title":"Infect Genet Evol"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0005758","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0005758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T15:52:59Z","timestamp":1539964379000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0005758"}},"subtitle":[],"editor":[{"given":"Melissa J.","family":"Caimano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2017,7,20]]},"references-count":10,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2017,7,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0005758","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pntd.0005758","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,20]]}}}