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In: Nu115 Fs, editor, 2010."},{"key":"ref2","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0001-706X(03)00029-9","article-title":"Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa","volume":"86","author":"MJ van der Werf","year":"2003","journal-title":"Acta Trop"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1128\/AAC.03809-14","article-title":"Lactate as a novel quantitative measure of viability in <italic>Schistosoma mansoni<\/italic> drug sensitivity assays","volume":"59","author":"S Howe","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0163-7258(82)90064-X","article-title":"The biology and toxicology of molluscicides, Bayluscide","volume":"19","author":"P Andrews","year":"1983","journal-title":"Pharmacol Ther"},{"issue":"2","key":"ref5","first-page":"139","article-title":"Effects of varying concentrations of the crude aqueous and ethanolic extracts of <italic>Dalbergia sissoo<\/italic> plant parts on <italic>Biomphalaria pfeifferi<\/italic> egg masses","volume":"6","author":"AA Adenusi","year":"2009","journal-title":"Afr J Tradit Complement Altern Med"},{"issue":"4","key":"ref6","first-page":"919","article-title":"Avalia\u00e7\u00e3o da bioatividade dos extratos de c\u00farcuma (<italic>Curcuma longa<\/italic> L., Zingiberaceae) em <italic>Artemia salina<\/italic> e <italic>Biomphalaria glabrata<\/italic>","volume":"19","author":"CRM da Silva Filho","year":"2009","journal-title":"Braz J Pharmacog"},{"issue":"22","key":"ref7","first-page":"2348","article-title":"Efficacy of ethanolic leaf extracts of <italic>Carica papaya<\/italic> and <italic>Terminalia catappa<\/italic> as molluscicides against the snail intermediate hosts of schistosomiasis","volume":"4","author":"VO Adetunji","year":"2010","journal-title":"J Med Plant Res"},{"issue":"50","key":"ref8","doi-asserted-by":"crossref","first-page":"10241","DOI":"10.5897\/AJB10.415","article-title":"The molliscicidal effects of <italic>Hyptis suaveolens<\/italic> on different stages of <italic>Bulinus globosus<\/italic> in the laboratory","volume":"10","author":"OT Salawu","year":"2011","journal-title":"Afr J Biotech"},{"issue":"8","key":"ref9","first-page":"70","article-title":"Molluscicidal effects of aqueous and ethanolic extracts of lemongrass (<italic>Cymbopogon citratus<\/italic>) leaf against the different developmental stages of <italic>Biomphalaria pfeifferi<\/italic>","volume":"5","author":"B Otarigho","year":"2012","journal-title":"New York Sci J"},{"key":"ref10","first-page":"157","article-title":"Effect of successive applications of the sublethal concentration of <italic>Solanum paniculatum<\/italic> in <italic>Subulina octona<\/italic> (Subulinidae)","volume":"5","author":"L Silva","year":"2012","journal-title":"J. Natural Prod"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"726","DOI":"10.3109\/13880209.2015.1073332","article-title":"Molluscicidal activity of <italic>Solanum elaeagnifolium<\/italic> seeds against <italic>Galba truncatula<\/italic> intermediate host of <italic>Fasciola hepatica<\/italic>: Identification of \u03b2-solamarine","volume":"54","author":"F Njeh","year":"2016","journal-title":"Pharm Biol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.colsurfb.2010.07.020","article-title":"Curcuminoids-loaded lipid nanoparticles: a novel approach towards malaria treatment","volume":"81","author":"AP Nayaka","year":"2010","journal-title":"Colloid Surf B"},{"key":"ref13","article-title":"Poly-D,L-lactic-co-glycolic acid-based artesunate nanoparticles; formulation, antimalarial and toxicity assessments","author":"K Dauda","journal-title":"J Zhejiang Univ-Sci B (Biomed & Biotechnol)"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1007\/s00436-011-2527-9","article-title":"Curcumin-loaded into PLGA nanoparticles: Preparation and <italic>in vitro<\/italic> schistosomicidal activity","volume":"110","author":"PP Luz","year":"2012","journal-title":"Parasitol Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.actatropica.2013.06.011","article-title":"Liposomal-praziquantel: Efficacy against <italic>Schistosoma mansoni<\/italic> in a preclinical assay","volume":"128","author":"TF Frezza","year":"2013","journal-title":"Acta trop"},{"issue":"1","key":"ref16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1089\/107555303321223035","article-title":"Safety and anti-inflammatory activity of curcumin: a component of tumeric (<italic>Curcuma longa<\/italic>)","volume":"9","author":"N Chainani-Wu","year":"2003","journal-title":"J Altern Complement Med"},{"key":"ref17","unstructured":"Jones E, Salin V, Williams GW. Nisin and the market for commercial bacteriocins. TAMRC Consumer and Product Research Report No. CP-01-05. 2005. Avaliable online: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/wwww.ageconsearch.umn.edu\/bitstream\/90779\/2\/CP%2001%2005%20Nisin%20Report.pdf\" xlink:type=\"simple\">http:\/\/wwww.ageconsearch.umn.edu\/bitstream\/90779\/2\/CP%2001%2005%20Nisin%20Report.pdf<\/ext-link> (accessed on 24 May 2017)."},{"key":"ref18","first-page":"44","article-title":"Turmeric and curcumin: Biological actions and medicinal applications","volume":"87","author":"C Ishita","year":"2004","journal-title":"Curr Sci"},{"issue":"3","key":"ref19","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/cam4.35","article-title":"Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1","volume":"1","author":"NE Joo","year":"2012","journal-title":"Cancer Med"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.imbio.2008.11.017","article-title":"Immunomodulatory effects of curcumin treatment on murine schistosomiasis mansoni","volume":"214","author":"G Allam","year":"2009","journal-title":"Immunobiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1007\/s00436-008-1311-y","article-title":"<italic>In vitro<\/italic> schistosomicidal activity of curcumin against <italic>Schistosoma mansoni<\/italic> adult worms","volume":"104","author":"LG Magalh\u00e3es","year":"2009","journal-title":"Parasitol Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.ejps.2009.02.019","article-title":"Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer","volume":"37","author":"J Shaikh","year":"2009","journal-title":"Euro J Pharm Sci"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.foodcont.2011.09.025","article-title":"Production of nisin-loaded solid lipid nanoparticles for sustained antimicrobial activity","volume":"24","author":"P Prombutara","year":"2012","journal-title":"Food Contrl"},{"issue":"3","key":"ref24","doi-asserted-by":"crossref","first-page":"823","DOI":"10.2307\/2403983","article-title":"Effect of calcium concentration on growth and egg laying of <italic>Helisoma duryi<\/italic>, <italic>Biomphalaria alexandrina<\/italic>, <italic>B<\/italic>. <italic>camerunensis<\/italic> and <italic>Bulinus truncatus<\/italic> (Gastropoda: Planorbidae)","volume":"24","author":"H Madsen","year":"1987","journal-title":"J Appl Ecol"},{"key":"ref25","first-page":"11","volume":"50","year":"1965"},{"key":"ref26","article-title":"UNDP\/World Bank\/WHO special programme for Research and Training in Tropical Diseases","year":"1983"},{"issue":"2","key":"ref27","doi-asserted-by":"crossref","first-page":"199","DOI":"10.4269\/ajtmh.1960.9.199","article-title":"The effects of low concentrations of sodium pentachlorophenate on the fecundity and egg viability of <italic>Australorbis glabratus<\/italic>","volume":"9","author":"L Olivier","year":"1960","journal-title":"Amer J Trop Med Hyg"},{"issue":"11","key":"ref28","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/S0020-7519(00)00114-4","article-title":"Molluscicidal activity of 2-hydroxy-3-alkyl-1, 4-naphthoquinones and derivatives","volume":"30","author":"AF dos Santos","year":"2000","journal-title":"Inter J Parasitol"},{"issue":"2","key":"ref29","first-page":"977","article-title":"Molluscidal activity of Mirazid on <italic>Biomphalaria alexandrina<\/italic> snails: biological and molecular studies","volume":"2","author":"GY Osman","year":"2014","journal-title":"Inter J Adv Res"},{"key":"ref30","unstructured":"Nobbmann ULF. Polydispersity\u2013what does it mean for DLS and chromatography? <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.materials-talks.com\/blog\/2014\/10\/23\/polydispersity-what-does-it-mean-for-dls-and-chromatography\" xlink:type=\"simple\">http:\/\/www.materials-talks.com\/blog\/2014\/10\/23\/polydispersity-what-does-it-mean-for-dls-and-chromatography<\/ext-link>, 2014. Accessed 24\/10\/2016"},{"issue":"9","key":"ref31","first-page":"1","article-title":"Cytoxicity effect of acetone extract of <italic>Curcuma longa<\/italic> in brine shrimp, <italic>Artemia salina<\/italic> (L)","volume":"2","author":"GP Srinivasan","year":"2014","journal-title":"Inter J Curr Biotech"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.tmaid.2007.12.004","article-title":"Preliminary laboratory assessment of the crude aqueous and ethanolic extracts of <italic>Dalbergia sissoo<\/italic> plant parts for molluscicidal, ovicid-al and cercaricidal activities","volume":"6","author":"AA Adenusi","year":"2008","journal-title":"Trav Med Inf Dis"},{"key":"ref33","first-page":"13","article-title":"Molluscicidal Effects of <italic>Talinum triangulare<\/italic> on <italic>Bulinus truncatus<\/italic>","volume":"22","author":"OC Okeke","year":"2011","journal-title":"Nig J Biotech"},{"issue":"5","key":"ref34","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1590\/S0074-02761997000500011","article-title":"Effects of Bayluscide on the survival and water-leaving behaviour of <italic>Biomphalaria straminea<\/italic>, snail host of schistosomiasis in northeast Brazil","volume":"92","author":"O Sarquis","year":"1997","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"ref35","first-page":"393","article-title":"Structural damage to the foot-sole epithelium of <italic>Bulinus africanus<\/italic> following exposure to a plant molluscicide","volume":"41","author":"TD Brackenbury","year":"1999","journal-title":"Malacologia"},{"issue":"1","key":"ref36","first-page":"50","article-title":"Study on reproductive performance, survivality mortality of plant glycoside of <italic>Abrus precatrious<\/italic>","volume":"2","author":"P Mahobiya","year":"2013","journal-title":"J Asian Resonance"},{"key":"ref37","first-page":"1","article-title":"The Toxicology of Molluscicides","author":"G Webb","year":"1987"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1590\/S0074-02761987000300005","article-title":"Molluscicidal activity of butanolic extract of <italic>Phytolacca dodecandra<\/italic> (endod) on <italic>Biomphalaria glabrata<\/italic>","volume":"82","author":"CP De souza","year":"1987","journal-title":"Mem Insti Oswaldo Cruz"},{"key":"ref39","first-page":"258","article-title":"Study on the effect of bromoacetamide upon the development of snail eggs","volume":"10","author":"Y Zhang","year":"1992","journal-title":"J Parasitol Parasitic Dis"},{"key":"ref40","first-page":"45","article-title":"Control of snail intermediate hosts of schistosomiasis","volume":"14","author":"CO Adewunmi","year":"1993","journal-title":"Nig J Parasitol"},{"key":"ref41","first-page":"183","article-title":"Toxicity of some molluscicides to freshwater snail <italic>Lymnaea auricularia<\/italic> the vector of animal fasciolasis and to non-target organisms","volume":"4","author":"BD Parashar","year":"1995","journal-title":"Proc. Acad. Environ. Biol."},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1073\/pnas.0608611104","article-title":"Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus","volume":"104","author":"SK Lai","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1016\/j.marenvres.2009.10.011","article-title":"The effects of silver nanoparticles on oyster embryos","volume":"69","author":"AH Ringwood","year":"2010","journal-title":"Marine Environ Res"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jhazmat.2010.10.115","article-title":"Effects of diamond nanoparticle exposure on the internal structure and reproduction of <italic>Daphnia magna<\/italic>","volume":"186","author":"E Mendon\u1e09a","year":"2011","journal-title":"J Hazard Mat"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.aquatox.2012.10.015","article-title":"Nanoparticle toxicity in <italic>Daphnia magna<\/italic> reproduction studies: the importance of test design","volume":"126","author":"F Seitz","year":"2013","journal-title":"Aquatic Toxicol"},{"issue":"8","key":"ref46","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1080\/17435390.2016.1177743","article-title":"Spermiotoxicity of nickel nanoparticles in the marine invertebrate <italic>Ciona intestinalis<\/italic> (ascidians)","volume":"10","author":"A Gallo","year":"2016","journal-title":"Nanotoxicol"},{"key":"ref47","first-page":"91","article-title":"Schistosomaisis control: Evaluation of the molluscicidal activity of a plant extract (<italic>Sesbania sesban<\/italic>) against <italic>Biomphalaria alexandrina<\/italic>","volume":"27","author":"ET Rizk","year":"1998","journal-title":"J Egypt Germ Soc Zool"},{"key":"ref48","first-page":"791","article-title":"Antischistosomal and liver protective effects of <italic>Curcuma longa<\/italic> extract in <italic>Schistosoma mansoni<\/italic> infected mice","volume":"45","author":"AE EL-Ansary","year":"2007","journal-title":"Indian J Expt Biol"},{"key":"ref49","first-page":"585","article-title":"The effects of myrrh (<italic>Commiphora molmol<\/italic>) on the infected snails of <italic>Schistosoma<\/italic> sp. and their egg masses: effect on shedding of cercariae and on snail fecundity","volume":"33","author":"AM Massoud","year":"2003","journal-title":"J Egypt Soc Parasitol"},{"key":"ref50","first-page":"206","article-title":"Effect of schistosomiasis infection on the clearance of phenazone (Antipyrine) in mice","volume":"40","author":"A Metwally","year":"1990","journal-title":"Arzneimittel-Forschung"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s00244-003-1181-3","article-title":"Effects of herbal molluscicides and their combinations on the reduction of the snail <italic>Lymnaea acuminate<\/italic>","volume":"46","author":"A Singh","year":"2004","journal-title":"Arch. Environ. Contam. Toxicol."}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0005855","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2017,9,5]],"date-time":"2017-09-05T00:00:00Z","timestamp":1504569600000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0005855","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T17:28:36Z","timestamp":1539970116000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0005855"}},"subtitle":[],"editor":[{"given":"Stephen W.","family":"Attwood","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2017,8,23]]},"references-count":51,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2017,8,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0005855","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pntd.0005855","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,23]]}}}