{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:09:01Z","timestamp":1777586941257,"version":"3.51.4"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2015\/13063-6"],"award-info":[{"award-number":["2015\/13063-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0006207","type":"journal-article","created":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T13:27:53Z","timestamp":1518442073000},"page":"e0006207","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":18,"title":["Clinical findings and prognosis of patients hospitalized for acute decompensated heart failure: Analysis of the influence of Chagas etiology and ventricular function"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7534-9627","authenticated-orcid":true,"given":"Ca\u00edque Bueno","family":"Terhoch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry Fukuda","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Moreira","family":"Ayub-Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germano Emilio","family":"Concei\u00e7\u00e3o-Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera Maria Cury","family":"Salemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Roberto","family":"Chizzola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mucio Tavares","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia Helena Gelas","family":"Lage","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edimar Alcides","family":"Bocchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor Sarli","family":"Issa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2018,2,12]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/S0140-6736(03)14464-9","article-title":"Physical examination in the care of medical inpatients: an observational study","volume":"362","author":"BM Reilly","year":"2003","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1016\/j.jacc.2006.10.036","article-title":"Wither the cardiac physical examination?","volume":"48","author":"AN DeMaria","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"i3309","DOI":"10.1136\/bmj.i3309","article-title":"How valuable is physical examination of the cardiovascular system?","volume":"354","author":"A Elder","year":"2016","journal-title":"BMJ"},{"key":"ref4","first-page":"891","article-title":"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)","volume":"18","author":"P Ponikowski","year":"2016","journal-title":"Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart Fail"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"3044","DOI":"10.1161\/CIRCULATIONAHA.109.870006","article-title":"The heart failure spectrum: time for a phenotype-oriented approach","volume":"119","author":"GW De Keuleaner","year":"2009","journal-title":"Circulation"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.jacc.2014.05.027","article-title":"The MOGE(S) classification of cardiomyopathy for clinicians","volume":"64","author":"E Arbustini","year":"2014","journal-title":"J Am Coll Cardiol"},{"key":"ref7","first-page":"820","article-title":"Third heart sound in hospitalised patients with acute heart failure: insights from the ATTEND study","volume":"69","author":"Y Minami","year":"2015"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1093\/eurheartj\/ehs444","article-title":"EVEREST Trial Investigators. Clinical course and predictive value of congestion during hospitalization in patients admitted for worsening signs and symptoms of heart failure with reduced ejection fraction: findings from the EVEREST trial","volume":"34","author":"AP Ambrosy","year":"2013","journal-title":"Eur Heart J"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1093\/eurheartj\/ehs070","article-title":"Discriminating clinical features of heart failure with preserved vs reduced ejection fraction in the community","volume":"33","author":"JE Ho","year":"2012","journal-title":"Eur Heart J"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1093\/eurheartj\/ehm102","article-title":"Prognosis of all-cause heart failure and borderline left ventricular systolic dysfunction: 5 year mortality follow-up of the Echocardiographic Heart of England Screening Study (ECHOES)","volume":"28","author":"FD Hobbs","year":"2007","journal-title":"Eur Heart J"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1056\/NEJMp1609055","article-title":"Meaning and the Nature of Physicians\u2019 Work","volume":"375","author":"DI Rosenthal","year":"2016","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1016\/j.amjcard.2016.08.080","article-title":"Etiology of heart failure and outcomes in patients hospitalized for acute decompensated heart failure with preserved or reduced ejection fraction","volume":"118","author":"K Kajimoto","year":"2016","journal-title":"Am J Cardiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.ijcard.2012.01.033","article-title":"Outcome of Chagas cardiomyopathy in comparison to ischemic cardiomyopathy","volume":"167","author":"LG1 Vilas Boas","year":"2013","journal-title":"Int J Cardiol"},{"issue":"2","key":"ref14","doi-asserted-by":"crossref","first-page":"e0003540","DOI":"10.1371\/journal.pntd.0003540","article-title":"Prevalence of Chagas disease in Latin-American migrants living in Europe: a systematic review and meta-analysis","volume":"9","author":"A1 Requena-M\u00e9ndez","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"issue":"12","key":"ref15","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/j.jacc.2017.08.004","article-title":"Chronic Chagas Heart Disease Management: From Etiology to Cardiomyopathy Treatment","volume":"70","author":"EA Bocchi","journal-title":"J Am Coll Cardiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1056\/NEJM197112232852601","article-title":"The natural history of congestive heart failure: Framingham study","volume":"285","author":"PA McKee","year":"1971","journal-title":"N Engl J Med"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.ijcard.2004.05.025","article-title":"Risk stratification in a Brazilian hospital-based cohort of 1220 outpatients with heart failure: role of Chagas' heart disease","volume":"102","author":"HF Freitas","year":"2005","journal-title":"Int J Cardiol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/S0735-1097(03)00309-7","article-title":"Clinical assessment identifies hemodynamic profiles that predict outcomes in patients admitted with heart failure","volume":"41","author":"A Nohria","year":"2003","journal-title":"J Am Coll Cardiol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.jacc.2005.03.051","article-title":"In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications: an analysis from the Acute Decompensated Heart Failure National Registry (ADHERE)","volume":"46","author":"WT Abraham","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/ejhf.679","article-title":"ESC-HFA HF Long-Term Registry investigators. In-hospital and 1-year mortality associated with diabetes in patients with acute heart failure: results from the ESC-HFA Heart Failure Long-Term Registry","volume":"19","author":"G Targher","year":"2017","journal-title":"Eur J Heart Fail"},{"key":"ref21","first-page":"433","article-title":"Investigadores Estudo BREATHE. I Brazilian Registry of Heart Failure\u2014clinical aspects, care quality and hospitalization outcomes","volume":"104","author":"DC Albuquerque","year":"2015","journal-title":"Arq Bras Cardiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.jacc.2013.06.013","article-title":"Interamerican Society of Cardiology. The reality of heart failure in Latin America","volume":"62","author":"EA Bocchi","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2990","DOI":"10.1016\/j.ijcard.2013.04.015","article-title":"Prognosis of patients with chronic systolic heart failure: Chagas disease versus systemic arterial hypertension","volume":"168","author":"RB Bestetti","year":"2013","journal-title":"Int J Cardiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1161\/CIRCHEARTFAILURE.109.882035","article-title":"Beta-blocker therapy and mortality of patients with Chagas cardiomyopathy: a subanalysis of the REMADHE prospective trial","volume":"3","author":"VS Issa","year":"2010","journal-title":"Circ Heart Fail"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1590\/1806-9282.63.01.57","article-title":"Decompensated chagasic heart failure versus non-chagasic heart failure at a tertiary care hospital: Clinical characteristics and outcomes","volume":"63","author":"LN Santos","year":"2017","journal-title":"Rev Assoc Med Bras"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jacc.2005.09.022","article-title":"ADHERE Scientific Advisory Committee and Investigators. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database","volume":"47","author":"CW Yancy","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/ejhf.566","article-title":"Heart Failure Association (HFA) of the European Society of Cardiology (ESC).European Society of Cardiology Heart Failure Long-Term Registry (ESC-HF-LT): 1-year follow-up outcomes and differences across regions","volume":"18","author":"MG Crespo-Leiro","year":"2016","journal-title":"Eur J Heart Fail"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"pii","DOI":"10.1161\/CIRCIMAGING.116.005571","article-title":"Evaluation of Right Ventricular Systolic Function in Chagas Disease Using Cardiac Magnetic Resonance Imaging","volume":"10","author":"HT Moreira","year":"2017","journal-title":"Circ Cardiovasc Imaging"},{"key":"ref29","first-page":"209","article-title":"Right ventricular Doppler echocardiographic study of indeterminate form of chagas disease","volume":"104","author":"RG Furtado","year":"2015","journal-title":"Arq Bras Cardiol"},{"issue":"1","key":"ref30","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ijcard.2003.05.003","article-title":"Morphofunctional characteristics of the right ventricle in Chagas' dilated cardiomyopathy","volume":"94","author":"C Nunes Mdo","year":"2004","journal-title":"Int J Cardiol"},{"issue":"2","key":"ref31","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1590\/S0037-86822012000200015","article-title":"Echocardiographic parameters associated with pulmonary congestion in outpatients with Chagas' cardiomyopathy and non-chagasic cardiomyopathy","volume":"45","author":"MM Barral","year":"2012","journal-title":"Rev Soc Bras Med Trop"},{"issue":"Suppl 1","key":"ref32","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1590\/S0074-02762009000900022","article-title":"Morbidity and prognostic factors in chronic chagasic cardiopathy","volume":"104","author":"MO Rocha","year":"2009","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1016\/j.jchf.2015.06.012","article-title":"Characteristics, Treatments, and Outcomes of Hospitalized Heart Failure Patients Stratified by Etiologies of Cardiomyopathy","volume":"3","author":"S Shore","year":"2015","journal-title":"JACC Heart Fail"},{"issue":"5","key":"ref34","first-page":"328","article-title":"Clinical characteristics, treatment, and prognosis of patients with ischemic and nonischemic acute severe heart failure. Analysis of data from the COMMIT-AHF registry","volume":"127","author":"M Ostr\u0119ga","year":"2017","journal-title":"Pol Arch Intern Med."},{"issue":"2","key":"ref35","first-page":"181","article-title":"Ischemic versus non-ischemic cardiomyopathy\u2014are there differences in prognosis? Experience of an advanced heart failure center","volume":"30","author":"C Louren\u00e7o","year":"2011","journal-title":"Rev Port Cardiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1590\/S1807-59322011000200010","article-title":"Predictors of low cardiac output in decompensated severe heart failure","volume":"66","author":"ME Ochiai","year":"2011","journal-title":"Clinics"},{"issue":"1","key":"ref37","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1161\/CIRCHEARTFAILURE.109.882035","article-title":"Beta-blocker therapy and mortality of patients with Chagas cardiomyopathy: a subanalysis of the REMADHE prospective trial","volume":"3","author":"VS Issa","year":"2010","journal-title":"Circ Heart Fail"},{"issue":"4","key":"ref38","doi-asserted-by":"crossref","first-page":"e2176","DOI":"10.1371\/journal.pntd.0002176","article-title":"Mode of death on Chagas heart disease: comparison with other etiologies. a subanalysis of the REMADHE prospective trial","volume":"7","author":"SM Ayub-Ferreira","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1038\/nrcardio.2012.109","article-title":". Diagnosis and management of Chagas disease and cardiomyopathy","volume":"9","author":"AL Ribeiro","year":"2012","journal-title":"Nat Rev Cardiol"}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0006207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T17:35:22Z","timestamp":1539970522000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0006207"}},"subtitle":[],"editor":[{"given":"Herbert B.","family":"Tanowitz","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2018,2,12]]},"references-count":39,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2018,2,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0006207","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,12]]}}}