{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T12:54:35Z","timestamp":1782564875291,"version":"3.54.5"},"update-to":[{"DOI":"10.1371\/journal.pntd.0006231","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T00:00:00Z","timestamp":1518048000000}}],"reference-count":69,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T00:00:00Z","timestamp":1517184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1008048"],"award-info":[{"award-number":["OPP1008048"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0006231","type":"journal-article","created":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T18:27:26Z","timestamp":1517250446000},"page":"e0006231","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":32,"title":["Estimating Cryptosporidium and Giardia disease burdens for children drinking untreated groundwater in a rural population in India"],"prefix":"10.1371","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7126-9168","authenticated-orcid":true,"given":"Miles E.","family":"Daniels","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woutrina A.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion W.","family":"Jenkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2018,1,29]]},"reference":[{"key":"ref1","article-title":"World Health Organization and Unicef. Progress on Sanitation and Drinking Water: 2015 Update and MDG Assessment","year":"2015"},{"issue":"5","key":"ref2","first-page":"e1001644","article-title":"Fecal contamination of drinking-water in low-and middle-income countries: a systematic review and meta-analysis","volume":"11","author":"R Bain","year":"2014"},{"key":"ref3","unstructured":"World Health Organization. Global Health Observatory Data 2012 [2015]. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/gho\/en\/\" xlink:type=\"simple\">http:\/\/www.who.int\/gho\/en\/<\/ext-link>."},{"issue":"2","key":"ref4","doi-asserted-by":"crossref","first-page":"289","DOI":"10.4269\/ajtmh.2010.09-0382","article-title":"Estimating the scope of household water treatment in low-and medium-income countries","volume":"82","author":"G Rosa","year":"2010","journal-title":"Am J Trop Med Hyg"},{"issue":"1","key":"ref5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2166\/wh.2006.002","article-title":"Waterborne transmission of protozoan parasites: a worldwide review of outbreaks and lessons learnt","volume":"5","author":"P Karanis","year":"2007","journal-title":"J Water Health"},{"issue":"11","key":"ref6","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.ijpara.2008.03.006","article-title":"Molecular characterisation of species and genotypes of <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> and assessment of zoonotic transmission","volume":"38","author":"L Xiao","year":"2008","journal-title":"Int J Parasitol"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1128\/CMR.17.1.72-97.2004","article-title":"<italic>Cryptosporidium<\/italic> taxonomy: recent advances and implications for public health","volume":"17","author":"L Xiao","year":"2004","journal-title":"Clin Microbiol Rev"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.pt.2006.02.015","article-title":"<italic>Giardia<\/italic> and <italic>Cryptosporidium<\/italic> join the &apos;Neglected Diseases Initiative&apos;","volume":"22","author":"L Savioli","year":"2006","journal-title":"Trends Parasitol"},{"issue":"9","key":"ref9","first-page":"e564","article-title":"Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED)","volume":"3","author":"JA Platts-Mills","year":"2015"},{"issue":"9888","key":"ref10","first-page":"209","article-title":"Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study","volume":"382","author":"KL Kotloff","year":"2013"},{"key":"ref11","article-title":"Improving diarrhoea estimates","author":"CF Lanata","year":"2002"},{"issue":"9306","key":"ref12","first-page":"564","article-title":"Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study","volume":"359","author":"DS Berkman","year":"2002"},{"issue":"5","key":"ref13","doi-asserted-by":"crossref","first-page":"e0004564","DOI":"10.1371\/journal.pntd.0004564","article-title":"Natural history of cryptosporidiosis in a longitudinal study of slum-dwelling Bangladeshi children: association with severe malnutrition","volume":"10","author":"PS Korpe","year":"2016","journal-title":"PLoS neglected tropical diseases"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1093\/cid\/ciw391","article-title":"A prospective longitudinal cohort to investigate the effects of early life giardiasis on growth and all cause diarrhea","volume":"63","author":"JR Donowitz","year":"2016","journal-title":"Clin Infect Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"596","DOI":"10.4269\/ajtmh.15-0111","article-title":"<italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> in Humans, Domestic Animals, and Village Water Sources in Rural India","author":"ME Daniels","year":"2015","journal-title":"Am J Trop Med Hyg"},{"key":"ref16","first-page":"161","article-title":"Risk assessment","author":"C Haas","year":"2001","journal-title":"Water Quality: Guidelines, Standards and Health"},{"issue":"9","key":"ref17","doi-asserted-by":"crossref","first-page":"5160","DOI":"10.1021\/es204381e","article-title":"Linking quantitative microbial risk assessment and epidemiological data: informing safe drinking water trials in developing countries","volume":"46","author":"KS Enger","year":"2012","journal-title":"Environ Sci Technol"},{"issue":"6","key":"ref18","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1289\/ehp.1003000","article-title":"Impacts of climate change on public health in India: future research directions","volume":"119","author":"KF Bush","year":"2011","journal-title":"Environ Health Perspect"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1080\/09603123.2014.989492","article-title":"Quantitative microbial risk assessment of <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> in well water from a native community of Mexico","volume":"25","author":"AP Balderrama-Carmona","year":"2015","journal-title":"Int J Environ Health Res"},{"issue":"3","key":"ref20","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1080\/09603123.2010.533367","article-title":"Risk of <italic>Giardia<\/italic> infection for drinking water and bathing in a peri-urban area in Sao Paulo, Brazil","volume":"21","author":"MTP Razzolini","year":"2011","journal-title":"Int J Environ Health Res"},{"key":"ref21","first-page":"645","article-title":"Effectiveness of a rural sanitation programme on diarrhoea, soil-transmitted helminth infection, and child malnutrition in Odisha, India: a cluster-randomised trial","volume":"2","author":"T Clasen","year":"2014"},{"issue":"1","key":"ref22","first-page":"7","article-title":"The effect of improved rural sanitation on diarrhoea and helminth infection: design of a cluster-randomized trial in Orissa, India","volume":"9","author":"T Clasen","year":"2012"},{"key":"ref23","article-title":"Quantitative microbial risk assessment","author":"CN Haas","year":"1999"},{"key":"ref24","article-title":"R: A language and environment for statistical computing","year":"2017"},{"issue":"6","key":"ref25","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1016\/S0043-1354(96)00387-9","article-title":"Assessment of the risk of infection by <italic>Cryptosporidium<\/italic> or <italic>Giardia<\/italic> in drinking water from a surface water source","volume":"31","author":"PFM Teunis","year":"1997","journal-title":"Water Res"},{"issue":"9","key":"ref26","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1128\/AEM.57.9.2610-2616.1991","article-title":"Occurrence of <italic>Giardia<\/italic> and <italic>Cryptosporidium<\/italic> spp. in surface water supplies","volume":"57","author":"MW LeChevallier","year":"1991","journal-title":"Appl Environ Microbiol"},{"key":"ref27","unstructured":"Pyramid Population. India 2016 2016 [cited 2016]. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/populationpyramid.net\/india\/2013\/\" xlink:type=\"simple\">https:\/\/populationpyramid.net\/india\/2013\/<\/ext-link>."},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1046\/j.1365-3156.1998.00175.x","article-title":"Prevalence of intestinal parasites in rural Southern Indians","volume":"3","author":"G Kang","year":"1998","journal-title":"Trop Med Int Health"},{"issue":"17","key":"ref29","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1080\/10643389.2014.1000761","article-title":"The characterization of feces and urine: A review of the literature to inform advanced treatment technology","volume":"45","author":"C Rose","year":"2015","journal-title":"Crit Rev Environ Sci Technol"},{"issue":"1\u20132","key":"ref30","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.vetpar.2010.03.008","article-title":"Molecular characterization and assessment of zoonotic transmission of <italic>Cryptosporidium<\/italic> from dairy cattle in West Bengal, India","volume":"171","author":"SM Khan","year":"2010","journal-title":"Vet Parasitol"},{"issue":"3","key":"ref31","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.vetpar.2010.12.048","article-title":"Molecular characterization of <italic>Cryptosporidium<\/italic> spp. in native breeds of cattle in Kaduna State, Nigeria","volume":"178","author":"BV Maikai","year":"2011","journal-title":"Vet Parasitol"},{"issue":"1","key":"ref32","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s11250-012-0202-5","article-title":"<italic>Cryptosporidium<\/italic> species detected in calves and cattle in Dagoretti, Nairobi, Kenya","volume":"44","author":"EK Kang\u2019ethe","year":"2012","journal-title":"Trop Anim Health Prod"},{"issue":"7","key":"ref33","first-page":"75","article-title":"First molecular characterization of <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> from bovines (<italic>Bos taurus<\/italic> and <italic>Bubalus bubalis<\/italic>) in Sri Lanka: unexpected absence of <italic>C<\/italic>. <italic>parvum<\/italic> from pre-weaned calves","volume":"7","author":"H Abeywardena","year":"2014"},{"issue":"2","key":"ref34","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.vetpar.2011.09.025","article-title":"Common occurrence of a unique <italic>Cryptosporidium ryanae<\/italic> variant in zebu cattle and water buffaloes in the buffer zone of the Chitwan National Park, Nepal","volume":"185","author":"Y Feng","year":"2012","journal-title":"Vet Parasitol"},{"key":"ref35","first-page":"149","article-title":"<italic>Cryptosporidium<\/italic>: parasite and disease","author":"LJ Robertson","year":"2014"},{"issue":"4","key":"ref36","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.pt.2010.01.004","article-title":"Minimal zoonotic risk of cryptosporidiosis from pet dogs and cats","volume":"26","author":"A Lucio-Forster","year":"2010","journal-title":"Trends Parasitol"},{"issue":"1","key":"ref37","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1128\/CMR.00033-10","article-title":"Zoonotic potential and molecular epidemiology of <italic>Giardia<\/italic> species and giardiasis","volume":"24","author":"Y Feng","year":"2011","journal-title":"Clin Microbiol Rev"},{"key":"ref38","first-page":"96","article-title":"First molecular characterisation of <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> from <italic>Bubalus bubalis<\/italic> (water buffalo) in Victoria, Australia","volume":"20","author":"H Abeywardena","year":"2013"},{"key":"ref39","first-page":"303","article-title":"Guidelines for drinking-water quality","volume":"216","author":"G WHO","year":"2011","journal-title":"World Health Organization"},{"key":"ref40","article-title":"Office of Research and Development","year":"2011"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.scitotenv.2012.06.057","article-title":"Water consumption patterns and factors contributing to water consumption in arsenic affected population of rural West Bengal, India","volume":"463","author":"MA Hossain","year":"2013","journal-title":"Sci Total Environ"},{"issue":"1","key":"ref42","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/0272-4332.00014","article-title":"<italic>Cryptosporidium<\/italic> dose response studies: variation between isolates","volume":"22","author":"PFM Teunis","year":"2002","journal-title":"Risk Anal"},{"key":"ref43","article-title":"<italic>Cryptosporidium<\/italic> in drinking water: evaluation of the ILSI quantitative risk assessment framework","author":"PFM Teunis","year":"1999"},{"issue":"6","key":"ref44","doi-asserted-by":"crossref","first-page":"709","DOI":"10.2105\/AJPH.81.6.709","article-title":"Risk assessment and control of waterborne giardiasis","volume":"81","author":"JB Rose","year":"1991","journal-title":"Am J Public Health"},{"issue":"3","key":"ref45","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1093\/cid\/cit288","article-title":"Cryptosporidiosis among children in an endemic semiurban community in southern India: does a protected drinking water source decrease infection?","volume":"57","author":"R Sarkar","year":"2013","journal-title":"Clin Infect Dis"},{"issue":"2","key":"ref46","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00436-008-1007-3","article-title":"Prevalence of enteroparasites and genotyping of <italic>Giardia lamblia<\/italic> in Peruvian children","volume":"103","author":"GP Cord\u00f3n","year":"2008","journal-title":"Parasitol Res"},{"issue":"10051","key":"ref47","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/S0140-6736(16)31529-X","article-title":"Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study","volume":"388","author":"J Liu","year":"2016","journal-title":"The Lancet"},{"issue":"5","key":"ref48","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1080\/00365540410021072","article-title":"An outbreak of cryptosporidiosis associated with exposure to swimming pool water","volume":"37","author":"M Insulander","year":"2005","journal-title":"Scand J Infect Dis Suppl"},{"issue":"01","key":"ref49","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1017\/S0950268897007589","article-title":"Cryptosporidiosis in children during a massive waterborne outbreak in Milwaukee, Wisconsin: clinical, laboratory and epidemiologic findings","volume":"119","author":"HG Cicirello","year":"1997","journal-title":"Epidemiol Infect"},{"issue":"6","key":"ref50","first-page":"518","article-title":"Outbreak of cryptosporidiosis after contamination of the public water supply in Saitama Prefecture, Japan, in 1996","volume":"74","author":"N Yamamoto","year":"2000"},{"issue":"02","key":"ref51","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1017\/S0950268800054297","article-title":"An outbreak of cryptosporidiosis in a hospital day-care centre","volume":"101","author":"JAGM Cristino","year":"1988","journal-title":"Epidemiol Infect"},{"key":"ref52","article-title":"Reporting errors in one-week diarrhoea recall surveys: experience from a prospective study in rural Bangladesh","author":"N Alam","year":"1989","journal-title":"Reporting errors in one-week diarrhoea recall surveys: experience from a prospective study in rural Bangladesh"},{"key":"ref53","unstructured":"Scientific T. Dynabeads GC-Combo 2016 [cited 2017 Nov-2017]. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/assets.thermofisher.com\/TFS-Assets\/LSG\/manuals\/DynabeadsGCCombo_man.pdf\" xlink:type=\"simple\">https:\/\/assets.thermofisher.com\/TFS-Assets\/LSG\/manuals\/DynabeadsGCCombo_man.pdf<\/ext-link>."},{"issue":"1","key":"ref54","doi-asserted-by":"crossref","first-page":"51","DOI":"10.2166\/wh.2007.142","article-title":"Incorporating method recovery uncertainties in stochastic estimates of raw water protozoan concentrations for QMRA","volume":"5","author":"SR Petterson","year":"2007","journal-title":"J Water Health"},{"key":"ref55","article-title":"Human fecal and pathogen exposure pathways in rural Indian villages and the effect of increased latrine coverage","author":"M Odagiri","year":"2016","journal-title":"Water Res"},{"issue":"7","key":"ref56","first-page":"75","article-title":"First molecular characterization of <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> from bovines (<italic>Bos taurus<\/italic> and <italic>Bubalus bubalis<\/italic>) in Sri Lanka: unexpected absence of <italic>C<\/italic>. <italic>parvum<\/italic> from pre-weaned calves","volume":"7","author":"H Abeywardena","year":"2014"},{"issue":"4","key":"ref57","doi-asserted-by":"crossref","first-page":"535","DOI":"10.2166\/wh.2009.101","article-title":"Comparing probabilistic microbial risk assessments for drinking water against daily rather than annualised infection probability targets","volume":"7","author":"RS Signor","year":"2009","journal-title":"J Water Health"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envsoft.2015.01.004","article-title":"A simple and efficient method for global sensitivity analysis based on cumulative distribution functions","volume":"67","author":"F Pianosi","year":"2015","journal-title":"Environ Model Software"},{"issue":"4","key":"ref59","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/0168-1605(93)90148-A","article-title":"Use of microbial risk assessment in setting US drinking water standards","volume":"18","author":"BA Macler","year":"1993","journal-title":"Int J Food Microbiol"},{"issue":"1","key":"ref60","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2166\/wh.2014.036","article-title":"Risk of diarrhoea from shallow groundwater contaminated with enteropathogens in the Kathmandu Valley, Nepal","volume":"13","author":"S Shrestha","year":"2015","journal-title":"J Water Health"},{"issue":"14","key":"ref61","doi-asserted-by":"crossref","first-page":"7498","DOI":"10.1021\/acs.est.5b05797","article-title":"Modeling <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> in ground and surface water sources in rural India: associations with latrines, livestock, damaged wells, and rainfall patterns","volume":"50","author":"ME Daniels","year":"2016","journal-title":"Environ Sci Technol"},{"issue":"3","key":"ref62","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.watres.2012.11.034","article-title":"The joint effects of efficacy and compliance: A study of household water treatment effectiveness against childhood diarrhea","volume":"47","author":"KS Enger","year":"2013","journal-title":"Water Res"},{"issue":"1","key":"ref63","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2166\/wh.2004.0001","article-title":"A systematic review of the health outcomes related to household water quality in developing countries","volume":"2","author":"S Gundry","year":"2004","journal-title":"J Water Health"},{"issue":"3","key":"ref64","first-page":"e0121907","article-title":"Effects of source-versus household contamination of tubewell water on child diarrhea in rural Bangladesh: a randomized controlled trial","volume":"10","author":"A Ercumen","year":"2015"},{"issue":"8","key":"ref65","first-page":"e1001497","article-title":"Effect of household-based drinking water chlorination on diarrhoea among children under five in Orissa, India: a double-blind randomised placebo-controlled trial","volume":"10","author":"S Boisson","year":"2013"},{"issue":"1","key":"ref66","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1128\/AEM.68.1.427-429.2002","article-title":"<italic>Cryptosporidium parvum<\/italic> mixed genotypes detected by PCR-restriction fragment length polymorphism analysis","volume":"68","author":"C Reed","year":"2002","journal-title":"Appl Environ Microbiol"},{"issue":"8","key":"ref67","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.pt.2007.06.002","article-title":"<italic>Cryptosporidium<\/italic> oocysts: challenging adversaries","volume":"23","author":"LJ Robertson","year":"2007","journal-title":"Trends Parasitol"},{"issue":"7","key":"ref68","first-page":"103","article-title":"An optimised and standardised test to determine the presence of the protozoa <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> in water","volume":"41","author":"G Stanfield","year":"2000"},{"issue":"2","key":"ref69","doi-asserted-by":"crossref","first-page":"263","DOI":"10.2166\/wh.2008.030","article-title":"Long-term study of <italic>Cryptosporidium<\/italic> and <italic>Giardia<\/italic> occurrence and quantitative microbial risk assessment in surface waters of Arizona in the USA","volume":"6","author":"H Ryu","year":"2008","journal-title":"J Water Health"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0006231","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T00:00:00Z","timestamp":1518048000000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0006231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T07:01:02Z","timestamp":1603695662000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0006231"}},"subtitle":[],"editor":[{"given":"Genevieve","family":"Milon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,1,29]]},"references-count":69,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2018,1,29]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0006231","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pntd.0006231","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,29]]}}}