{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T05:33:56Z","timestamp":1785821636734,"version":"3.56.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0007189","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T00:00:00Z","timestamp":1552348800000}}],"reference-count":56,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T00:00:00Z","timestamp":1550534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"crossref","award":["UF140610"],"award-info":[{"award-number":["UF140610"]}],"id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000288","name":"Royal Society","doi-asserted-by":"crossref","award":["UF090083"],"award-info":[{"award-number":["UF090083"]}],"id":[{"id":"10.13039\/501100000288","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["204521\/Z\/16\/Z"],"award-info":[{"award-number":["204521\/Z\/16\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/J004227\/1"],"award-info":[{"award-number":["BB\/J004227\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/J004235\/1"],"award-info":[{"award-number":["BB\/J004235\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BBS\/E\/D\/20002173"],"award-info":[{"award-number":["BBS\/E\/D\/20002173"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1126862"],"award-info":[{"award-number":["OPP1126862"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0007189","type":"journal-article","created":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T14:01:25Z","timestamp":1550584885000},"page":"e0007189","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Parasite specific 7SL-derived small RNA is an effective target for diagnosis of active trypanosomiasis infection"],"prefix":"10.1371","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7902-2365","authenticated-orcid":true,"given":"Stephen M.","family":"Chiweshe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter C.","family":"Steketee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1524-2232","authenticated-orcid":true,"given":"Siddharth","family":"Jayaraman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith","family":"Paxton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4311-9776","authenticated-orcid":true,"given":"Kyriaki","family":"Neophytou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Erasmus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Labuschagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1159-142X","authenticated-orcid":true,"given":"Anneli","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0150-5049","authenticated-orcid":true,"given":"Annette","family":"MacLeod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Finn E.","family":"Grey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8304-9066","authenticated-orcid":true,"given":"Liam J.","family":"Morrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2019,2,19]]},"reference":[{"issue":"14","key":"ref1","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1017\/S0031182016001268","article-title":"The animal trypanosomiases and their chemotherapy: a review","volume":"143","author":"F Giordani","year":"2016","journal-title":"Parasitology"},{"issue":"9394","key":"ref2","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/S0140-6736(03)14694-6","article-title":"The trypanosomiases","volume":"362","author":"MP Barrett","year":"2003","journal-title":"Lancet"},{"issue":"10110","key":"ref3","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1016\/S0140-6736(17)31510-6","article-title":"Human African trypanosomiasis","volume":"390","author":"P Buscher","year":"2017","journal-title":"Lancet"},{"issue":"8","key":"ref4","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.pt.2016.04.012","article-title":"Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host Species","volume":"32","author":"LJ Morrison","year":"2016","journal-title":"Trends Parasitol"},{"issue":"10","key":"ref5","doi-asserted-by":"crossref","first-page":"e3244","DOI":"10.1371\/journal.pntd.0003244","article-title":"First WHO meeting of stakeholders on elimination of gambiense Human African Trypanosomiasis","volume":"8","author":"P. Holmes","year":"2014","journal-title":"PLoS neglected tropical diseases"},{"issue":"4","key":"ref6","first-page":"384","article-title":"The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis","volume":"27","author":"PT Woo","year":"1970","journal-title":"Acta Trop"},{"issue":"3","key":"ref7","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/0035-9203(79)90092-0","article-title":"<italic>Trypanosoma brucei<\/italic>: Miniature anion-exchange centrifugation technique for detection of low parasitaemias: Adaptation for field use","volume":"73","author":"WH Lumsden","year":"1979","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1177\/004947559402400204","article-title":"The quantitative buffy coat for the diagnosis of trypanosomes","volume":"24","author":"JW Bailey","year":"1994","journal-title":"Trop Doct"},{"issue":"11","key":"ref9","doi-asserted-by":"crossref","first-page":"e471","DOI":"10.1371\/journal.pntd.0000471","article-title":"Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for sleeping sickness diagnosis and staging","volume":"3","author":"P Buscher","year":"2009","journal-title":"PLoS neglected tropical diseases"},{"issue":"3","key":"ref10","first-page":"169","article-title":"A card-agglutination test with stained trypanosomes (C.A.T.T.) for the serological diagnosis of <italic>T<\/italic>. <italic>b<\/italic>. <italic>gambiense<\/italic> trypanosomiasis","volume":"58","author":"E Magnus","year":"1978","journal-title":"Ann Soc Belg Med Trop"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"e0004608","DOI":"10.1371\/journal.pntd.0004608","article-title":"Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of <italic>Trypanosoma brucei gambiense<\/italic> Infection: A Multi-centric Prospective Study","volume":"10","author":"S Bisser","year":"2016","journal-title":"PLoS neglected tropical diseases"},{"issue":"7","key":"ref12","doi-asserted-by":"crossref","first-page":"e0180555","DOI":"10.1371\/journal.pone.0180555","article-title":"Performance of the SD BIOLINE(R) HAT rapid test in various diagnostic algorithms for gambiense human African trypanosomiasis in the Democratic Republic of the Congo","volume":"12","author":"C Lumbala","year":"2017","journal-title":"PLoS One"},{"issue":"5","key":"ref13","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.ijpara.2007.09.006","article-title":"African trypanosomiasis: sensitive and rapid detection of the sub-genus Trypanozoon by loop-mediated isothermal amplification (LAMP) of parasite DNA","volume":"38","author":"ZK Njiru","year":"2008","journal-title":"Int J Parasitol"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"e1572","DOI":"10.1371\/journal.pntd.0001572","article-title":"Loop-mediated isothermal amplification technology: towards point of care diagnostics","volume":"6","author":"ZK Njiru","year":"2012","journal-title":"PLoS neglected tropical diseases"},{"issue":"1\u20132","key":"ref15","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.vetpar.2007.03.022","article-title":"Comparing FAMACHA eye color chart and Hemoglobin Color Scale tests for detecting anemia and improving treatment of bovine trypanosomosis in West Africa","volume":"147","author":"D Grace","year":"2007","journal-title":"Vet Parasitol"},{"issue":"6","key":"ref16","doi-asserted-by":"crossref","first-page":"e2936","DOI":"10.1371\/journal.pntd.0002936","article-title":"Proteomic selection of immunodiagnostic antigens for <italic>Trypanosoma congolense<\/italic>","volume":"8","author":"JR Fleming","year":"2014","journal-title":"PLoS neglected tropical diseases"},{"issue":"9","key":"ref17","doi-asserted-by":"crossref","first-page":"e0004977","DOI":"10.1371\/journal.pntd.0004977","article-title":"Proteomic Identification of Immunodiagnostic Antigens for <italic>Trypanosoma vivax<\/italic> Infections in Cattle and Generation of a Proof-of-Concept Lateral Flow Test Diagnostic Device","volume":"10","author":"JR Fleming","year":"2016","journal-title":"PLoS neglected tropical diseases"},{"issue":"1","key":"ref18","doi-asserted-by":"crossref","first-page":"9019","DOI":"10.1038\/s41598-018-26732-7","article-title":"Development of a Nanobody-based lateral flow assay to detect active <italic>Trypanosoma congolense<\/italic> infections","volume":"8","author":"JE Pinto Torres","year":"2018","journal-title":"Scientific reports"},{"issue":"6","key":"ref19","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nrc3066","article-title":"Cell-free nucleic acids as biomarkers in cancer patients","volume":"11","author":"H Schwarzenbach","year":"2011","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"ref20","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1093\/nar\/gkr786","article-title":"RNA-seq analysis of small RNPs in <italic>Trypanosoma brucei<\/italic> reveals a rich repertoire of non-coding RNAs","volume":"40","author":"S Michaeli","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"D457","DOI":"10.1093\/nar\/gkp851","article-title":"TriTrypDB: a functional genomic resource for the Trypanosomatidae","volume":"38","author":"M Aslett","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.mib.2014.06.006","article-title":"Non-coding RNA and the complex regulation of the trypanosome life cycle","volume":"20","author":"S. Michaeli","year":"2014","journal-title":"Curr Opin Microbiol"},{"issue":"8","key":"ref23","doi-asserted-by":"crossref","first-page":"e1283","DOI":"10.1371\/journal.pntd.0001283","article-title":"The short non-coding transcriptome of the protozoan parasite <italic>Trypanosoma cruzi<\/italic>","volume":"5","author":"O Franzen","year":"2011","journal-title":"PLoS neglected tropical diseases"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1080\/15476286.2015.1038019","article-title":"Genome-wide analysis of small nucleolar RNAs of <italic>Leishmania major<\/italic> reveals a rich repertoire of RNAs involved in modification and processing of rRNA","volume":"12","author":"D Eliaz","year":"2015","journal-title":"RNA biology"},{"issue":"9","key":"ref25","doi-asserted-by":"crossref","first-page":"3416","DOI":"10.1073\/pnas.1117313109","article-title":"Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species","volume":"109","author":"AP Jackson","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"4","key":"ref26","first-page":"307","article-title":"A comparative evaluation of the parasitological techniques currently available for the diagnosis of African trypanosomiasis in cattle","volume":"39","author":"J Paris","year":"1982","journal-title":"Acta Trop"},{"key":"ref27","article-title":"Procedures for determination of PCV (haematocrit) and Presence of Trypanosomes (phase contrast buffy coat) in Cattle","author":"M Murray","year":"1983"},{"issue":"3","key":"ref28","doi-asserted-by":"crossref","first-page":"e618","DOI":"10.1371\/journal.pntd.0000618","article-title":"Complete in vitro life cycle of <italic>Trypanosoma congolense<\/italic>: development of genetic tools","volume":"4","author":"V Coustou","year":"2010","journal-title":"PLoS neglected tropical diseases"},{"issue":"2","key":"ref29","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/0169-4758(94)90402-2","article-title":"Axenic culture of African trypanosome bloodstream forms","volume":"10","author":"H Hirumi","year":"1994","journal-title":"Parasitol Today"},{"issue":"10","key":"ref30","doi-asserted-by":"crossref","first-page":"e1003686","DOI":"10.1371\/journal.ppat.1003686","article-title":"The TgsGP gene is essential for resistance to human serum in <italic>Trypanosoma brucei gambiense<\/italic>","volume":"9","author":"P Capewell","year":"2013","journal-title":"PLoS pathogens"},{"key":"ref31","unstructured":"Andrews S. FastQC A Quality Control tool for High Throughput Sequence Data 2010."},{"key":"ref32","first-page":"1","article-title":"Cutadapt Removes Adapter Sequences From High-Throughput Sequencing Reads","volume":"17","author":"M. Martin","year":"2011","journal-title":"EMBnetjournal"},{"issue":"2","key":"ref33","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/bioinformatics\/btu638","article-title":"HTSeq\u2014a Python framework to work with high-throughput sequencing data","volume":"31","author":"S Anders","year":"2015","journal-title":"Bioinformatics"},{"issue":"4","key":"ref34","doi-asserted-by":"crossref","first-page":"R42","DOI":"10.1186\/gb-2009-10-4-r42","article-title":"A whole-genome assembly of the domestic cow, <italic>Bos taurus<\/italic>","volume":"10","author":"AV Zimin","year":"2009","journal-title":"Genome biology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.biosystems.2017.10.004","article-title":"On universal coding events in protein biogenesis","volume":"164","author":"V Kubyshkin","year":"2018","journal-title":"Biosystems"},{"issue":"3","key":"ref36","doi-asserted-by":"crossref","first-page":"e1006245","DOI":"10.1371\/journal.ppat.1006245","article-title":"Exosome secretion affects social motility in <italic>Trypanosoma brucei<\/italic>","volume":"13","author":"D Eliaz","year":"2017","journal-title":"PLoS pathogens"},{"key":"ref37","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.17716","article-title":"The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes","volume":"5","author":"P Capewell","year":"2016","journal-title":"Elife"},{"issue":"7","key":"ref38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005744","article-title":"The Dermis as a Delivery Site of <italic>Trypanosoma brucei<\/italic> for Tsetse Flies","volume":"12","author":"G Caljon","year":"2016","journal-title":"PLoS pathogens"},{"issue":"6","key":"ref39","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/j.chom.2016.05.002","article-title":"<italic>Trypanosoma brucei<\/italic> Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice","volume":"19","author":"S Trindade","year":"2016","journal-title":"Cell Host Microbe"},{"issue":"3\u20134","key":"ref40","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.vetpar.2011.03.021","article-title":"Loop-mediated isothermal amplification test for <italic>Trypanosoma vivax<\/italic> based on satellite repeat DNA","volume":"180","author":"ZK Njiru","year":"2011","journal-title":"Vet Parasitol"},{"issue":"3","key":"ref41","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.actatropica.2007.05.004","article-title":"Species-specific loop-mediated isothermal amplification (LAMP) for diagnosis of trypanosomosis","volume":"102","author":"OM Thekisoe","year":"2007","journal-title":"Acta Trop"},{"issue":"9","key":"ref42","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1039\/C0CC03957H","article-title":"One-step ultrasensitive detection of microRNAs with loop-mediated isothermal amplification (LAMP)","volume":"47","author":"C Li","year":"2011","journal-title":"Chem Commun (Camb)"},{"issue":"80","key":"ref43","doi-asserted-by":"crossref","first-page":"11040","DOI":"10.1039\/C7CC06140D","article-title":"One-step detection of microRNA with high sensitivity and specificity via target-triggered loop-mediated isothermal amplification (TT-LAMP)","volume":"53","author":"Y Sun","year":"2017","journal-title":"Chem Commun (Camb)"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ab.2017.12.003","article-title":"New Fpg probe chemistry for direct detection of recombinase polymerase amplification on lateral flow strips","volume":"543","author":"ML Powell","year":"2018","journal-title":"Anal Biochem"},{"issue":"7","key":"ref45","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1373\/clinchem.2015.245829","article-title":"Recombinase Polymerase Amplification for Diagnostic Applications","volume":"62","author":"RK Daher","year":"2016","journal-title":"Clin Chem"},{"issue":"11","key":"ref46","doi-asserted-by":"crossref","first-page":"e112146","DOI":"10.1371\/journal.pone.0112146","article-title":"Equipment-free incubation of recombinase polymerase amplification reactions using body heat","volume":"9","author":"ZA Crannell","year":"2014","journal-title":"PLoS One"},{"issue":"6","key":"ref47","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1021\/acssensors.6b00105","article-title":"Simple isothermal strategy for mulitplexed, rapid, sensitive and accurate miRNA detection","volume":"1","author":"EJH Wee","year":"2016","journal-title":"ACS Sensors"},{"issue":"4","key":"ref48","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1080\/15476286.2016.1274852","article-title":"RNA-mediated communication between helminths and their hosts: The missing links","volume":"14","author":"J Claycomb","year":"2017","journal-title":"RNA Biol"},{"issue":"2","key":"ref49","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/mmi.12949","article-title":"Assembling the components of the quorum sensing pathway in African trypanosomes","volume":"96","author":"BM Mony","year":"2015","journal-title":"Mol Microbiol"},{"issue":"7","key":"ref50","doi-asserted-by":"crossref","first-page":"e1005733","DOI":"10.1371\/journal.ppat.1005733","article-title":"<italic>Trypanosoma brucei<\/italic> Co-opts NK Cells to Kill Splenic B2 B Cells","volume":"12","author":"D Frenkel","year":"2016","journal-title":"PLoS pathogens"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1186\/s12864-015-1260-7","article-title":"Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world <italic>Leishmania<\/italic> providing evidence for conserved exosomal RNA Packaging","volume":"16","author":"U Lambertz","year":"2015","journal-title":"BMC genomics"},{"issue":"1\u20132","key":"ref52","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.molbiopara.2015.03.003","article-title":"Profiling of small RNA cargo of extracellular vesicles shed by <italic>Trypanosoma cruzi<\/italic> reveals a specific extracellular signature","volume":"199","author":"T Fernandez-Calero","year":"2015","journal-title":"Mol Biochem Parasitol"},{"issue":"7","key":"ref53","doi-asserted-by":"crossref","first-page":"e40705","DOI":"10.1371\/journal.pone.0040705","article-title":"Dicer-dependent biogenesis of small RNAs derived from 7SL RNA","volume":"7","author":"YF Ren","year":"2012","journal-title":"PLoS One"},{"issue":"20","key":"ref54","doi-asserted-by":"crossref","first-page":"18271","DOI":"10.1074\/jbc.M209215200","article-title":"The trypanosomatid signal recognition particle consists of two RNA molecules, a 7SL RNA homologue and a novel tRNA-like molecule","volume":"278","author":"L Liu","year":"2003","journal-title":"J Biol Chem"},{"issue":"2","key":"ref55","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0166-6851(93)90198-7","article-title":"Identification of a tRNA-like molecule that copurifies with the 7SL RNA of <italic>Trypanosoma brucei<\/italic>","volume":"57","author":"O Beja","year":"1993","journal-title":"Mol Biochem Parasitol"},{"issue":"20","key":"ref56","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.1093\/nar\/gni178","article-title":"Real-time quantification of microRNAs by stem-loop RT-PCR","volume":"33","author":"C Chen","year":"2005","journal-title":"Nucleic Acids Res"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0007189","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T00:00:00Z","timestamp":1552348800000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0007189","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T17:49:03Z","timestamp":1588960143000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0007189"}},"subtitle":[],"editor":[{"given":"Guy","family":"Caljon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,2,19]]},"references-count":56,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2019,2,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0007189","relation":{"new_version":[{"id-type":"doi","id":"10.1371\/journal.pntd.0007189","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,19]]}}}