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Intestinal Worms. Strongyloidiasis. Epidemiology. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.who.int\/intestinal_worms\/epidemiology\/strongyloidiasis\/en\/\" xlink:type=\"simple\">http:\/\/www.who.int\/intestinal_worms\/epidemiology\/strongyloidiasis\/en\/<\/ext-link>. Cited 5 August 2018."},{"issue":"10","key":"ref2","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.trstmh.2009.02.013","article-title":"Strongyloidiasis\u2014the most neglected of the neglected tropical diseases?","volume":"103","author":"A Olsen","year":"2009","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/bs.apar.2015.02.005","article-title":"Strongyloidiasis with emphasis on human infections and its different clinical forms","volume":"88","author":"R Toledo","year":"2015","journal-title":"Adv Parasitol"},{"issue":"10117","key":"ref4","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/S0140-6736(17)31930-X","article-title":"Soil-transmitted helminth infections","volume":"391","author":"PM Jourdan","year":"2018","journal-title":"Lancet"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"e0006229","DOI":"10.1371\/journal.pntd.0006229","article-title":"Accuracy of molecular biology techniques for the diagnosis of <italic>Strongyloides stercoralis<\/italic> infection\u2014A systematic review and meta-analysis","volume":"12","author":"D Buonfrate","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"issue":"7","key":"ref6","doi-asserted-by":"crossref","first-page":"e2288","DOI":"10.1371\/journal.pntd.0002288","article-title":"Strongyloides stercoralis: Global Distribution and Risk Factors","volume":"7","author":"F Schar","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph13050517","article-title":"Strongyloidiasis: A Disease of Socioeconomic Disadvantage","volume":"13","author":"M Beknazarova","year":"2016","journal-title":"Int J Environ Res Public Health"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"f5219","DOI":"10.1136\/bmj.f5219","article-title":"Simply wearing footwear could interrupt transmission of <italic>Strongyloides stercoralis<\/italic>","volume":"347","author":"DN Durrheim","year":"2013","journal-title":"BMJ"},{"issue":"4","key":"ref9","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.jinf.2017.08.007","article-title":"The changing aetiology of eosinophilia in migrants and returning travellers in the Hospital for Tropical Diseases, London 2002\u20132015: An observational study","volume":"75","author":"J Barrett","year":"2017","journal-title":"J Infect"},{"issue":"12","key":"ref10","doi-asserted-by":"crossref","first-page":"e0189449","DOI":"10.1371\/journal.pone.0189449","article-title":"Surveillance of strongyloidiasis in Spanish in-patients (1998\u20132014)","volume":"12","author":"M Belhassen-Garcia","year":"2017","journal-title":"PLoS One"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ijid.2015.11.015","article-title":"Strongyloidiasis in a young French woman raises concern about possible ongoing autochthonous transmission in Spain","volume":"42","author":"A Duvignaud","year":"2016","journal-title":"Int J Infect Dis"},{"issue":"8","key":"ref12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1093\/trstmh\/trt053","article-title":"<italic>Strongyloides stercoralis<\/italic>, the hidden worm. 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Diagnosis by bronchoalveolar cytology","volume":"58","author":"E Mayayo","year":"2005","journal-title":"J Clin Pathol"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jinf.2004.01.016","article-title":"Characteristics and geographical profile of strongyloidiasis in healthcare area 11 of the Valencian community (Spain)","volume":"49","author":"C Oltra Alcaraz","year":"2004","journal-title":"J Infect"},{"issue":"9","key":"ref16","doi-asserted-by":"crossref","first-page":"477","DOI":"10.4321\/S0212-71992003000900008","article-title":"<italic>Strongyloides stercoralis<\/italic> en el sur de Galicia","volume":"20","author":"C Mart\u00ednez-V\u00e1zquez","year":"2003","journal-title":"An. Med. Interna (Madrid)"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"336","DOI":"10.4269\/ajtmh.2003.69.336","article-title":"High prevalence of <italic>Strongyloides stercoralis<\/italic> among farm workers on the Mediterranean coast of Spain: analysis of the predictive factors of infection in developed countries","volume":"69","author":"P Rom\u00e1n-S\u00e1nchez","year":"2003","journal-title":"Am J Trop Med Hyg"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1093\/qjmed\/94.7.357","article-title":"Endemic strongyloidiasis on the Spanish Mediterranean coast","volume":"94","author":"P Rom\u00e1n S\u00e1nchez","year":"2001","journal-title":"QJM"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0014-2565(01)70755-2","article-title":"Actividad laboral agr\u00edcola y estrongiloidiasis. Estudio caso-control","volume":"201","author":"D Rodr\u00edguez Calabuig","year":"2001","journal-title":"Rev Clin Esp"},{"issue":"8","key":"ref20","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/S0300-2896(15)30730-4","article-title":"Infecci\u00f3n por <italic>Strongyloides stercoralis<\/italic> en un paciente con obstrucci\u00f3n cr\u00f3nica al flujo a\u00e9reo corticodependiente","volume":"32","author":"MJ Cremades Romero","year":"1996","journal-title":"Arch Bronconeumol"},{"key":"ref21","first-page":"271","article-title":"Treinta casos de estrongiloidiasis en un centro de atenci\u00f3n primaria: caracter\u00edsticas y posibles complicaciones","volume":"31","author":"D Rodr\u00edguez Calabuig","year":"1998","journal-title":"Aten Primaria"},{"issue":"5","key":"ref22","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.medin.2009.06.006","article-title":"Hiperinfecci\u00f3n por <italic>Strongyloides stercoralis<\/italic>","volume":"34","author":"J Llagunes","year":"2010","journal-title":"Med Intensiva"},{"issue":"11","key":"ref23","first-page":"512","article-title":"Respiratory distress and purpura in an immunocompromised patient: hyperinfestation with dissemination of <italic>Strongyloides stercoralis<\/italic>","volume":"141","author":"A Esteve-Martinez","year":"2013","journal-title":"Med Clin (Barc)"},{"issue":"8","key":"ref24","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/j.ejim.2004.10.002","article-title":"Disseminated strongyloidiasis in a patient with acquired immunodeficiency syndrome","volume":"15","author":"JM Olmos","year":"2004","journal-title":"Eur J Intern Med"},{"issue":"3","key":"ref25","first-page":"155","article-title":"<italic>Strongyloides stercoralis<\/italic> infestation in an immunocompetent 82-year-old woman","volume":"44","author":"V Lopez Gaona","year":"2009","journal-title":"Rev Esp Geriatr Gerontol"},{"issue":"7","key":"ref26","first-page":"310","article-title":"<italic>Strongyloides<\/italic>, a dangerous unknown","volume":"149","author":"R Escudero Sanchez","year":"2017","journal-title":"Med Clin (Barc)"},{"issue":"1","key":"ref27","first-page":"24","article-title":"<italic>Strongyloides stercoralis<\/italic> infection in a Spanish regional hospital: Not just an imported disease","volume":"36","author":"MI Pacheco-Tenza","year":"2018","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"8","key":"ref28","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.arbres.2016.01.010","article-title":"Pulmonary <italic>Strongyloides stercoralis<\/italic> infection","volume":"52","author":"V Esteban Ronda","year":"2016","journal-title":"Arch Bronconeumol"},{"issue":"2","key":"ref29","first-page":"e0006272","article-title":"Management of severe strongyloidiasis attended at reference centers in Spain","volume":"12","author":"A Martinez-Perez","year":"2018","journal-title":"PLoS Med"},{"issue":"25","key":"ref30","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1157\/13111836","article-title":"D. Estrongiloidiasis: epidemiolog\u00eda, manifestaciones cl\u00ednicas y diagn\u00f3stico. Experiencia en una zona end\u00e9mica: la comarca de La Safor (Valencia)","author":"R Igual-Adell","year":"2007","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0014-2565(01)71384-7","article-title":"Infestaci\u00f3n por <italic>Strongyloides stercolaris<\/italic> en pacientes con enfermedad pulmonar obstructiva cr\u00f3nica en la Vega del Segura (Murcia). Presentaci\u00f3n de tres casos","volume":"201","author":"L Pretel Serrano","year":"2001","journal-title":"Rev Clin Esp"},{"issue":"8","key":"ref32","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S0300-2896(08)72110-0","article-title":"<italic>Strongyloides stercoralys<\/italic>: una peculiar forma de exacerbaci\u00f3n en la epoc","volume":"44","author":"M Ortiz Romero","year":"2008","journal-title":"Arch Bronconeumol"},{"key":"ref33","first-page":"431","article-title":"Estrongiloidiasis en un paciente con el s\u00ecndrome de inmunodeficiencia adquirida","volume":"10","author":"N Batista","year":"1992","journal-title":"Enf Infecc Microbiol Clin"},{"key":"ref34","unstructured":"Llenas Garc\u00eda J, Pacheco Tenza I, Lucas Dato A, Gonzalez Cuello, Garcia Lopez M, Ruiz Macia J.A et al. 0601 Estrongiloidiasis aut\u00f3ctona e importada en un hospital comarcal del levante espa\u00f1ol. Abstracts SEIMC 2018. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.elsevier.es\/ficheros\/congresos\/congreso2018_eimc.pdf\" xlink:type=\"simple\">http:\/\/www.elsevier.es\/ficheros\/congresos\/congreso2018_eimc.pdf<\/ext-link>. Cited 5 August 2018"},{"key":"ref35","unstructured":"Tornero C, Orta N, Llopis M, Martinez M, Pariente M, Perea M et al. 0986. \u00bfEs la comarca de la Safor todav\u00eda un \u00e1rea end\u00e9mica de estrongiloides? Abstracts SEIMC 2018. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.elsevier.es\/ficheros\/congresos\/congreso2018_eimc.pdf\" xlink:type=\"simple\">http:\/\/www.elsevier.es\/ficheros\/congresos\/congreso2018_eimc.pdf<\/ext-link>. Cited 5 August 2018."},{"key":"ref36","unstructured":"Corbacho Loarte MD, Abelenda Alonso G, de la Fuente Crespo E, Mu\u00f1oz Valera MT, de Juan lvarez C, Merino Fernandez F.J. et al 807. Caracter\u00edsticas epidemiol\u00f3gicas de los pacientes diagnosticados de estrongiloidiasis en el hospital universitario Severo Ochoa. Abstracts SEIMC 2017. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.seimc.org\/contenidos\/congresosyeventos\/seimcanteriores\/seimc-EIMC-2017.pdf\" xlink:type=\"simple\">https:\/\/www.seimc.org\/contenidos\/congresosyeventos\/seimcanteriores\/seimc-EIMC-2017.pdf<\/ext-link> Cited 5 August 2018"},{"key":"ref37","unstructured":"Garcia Garcia A, Navalpotro Rodriguez D, Tormo Palop N, Ramos Mart JL, Chanza Avi\u00f1on M, Ocete Mochon M.D. et al 203. \u00bfEs necesario descartar la infecci\u00f3n por Strongyloides stercoralis en todo paciente que siga o inicie tratamiento inmunosupresor? Abstracts SEIMC 2011. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.seimc.org\/contenidos\/congresosyeventos\/seimcanteriores\/seimc-EIMC-2011.pdf\" xlink:type=\"simple\">https:\/\/www.seimc.org\/contenidos\/congresosyeventos\/seimcanteriores\/seimc-EIMC-2011.pdf<\/ext-link>. Cited 5 August 2018"},{"key":"ref38","unstructured":"Igual R, Dom\u00ednguez V, Alonso C, Guna R. 611. Las parasitosis intestinales como causa de eosinof\u00edlia. Abstracts SEIMC 2006. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.seimc.org\/contenidos\/congresosyeventos\/seimcanteriores\/seimc-EIMC-2006.pdf\" xlink:type=\"simple\">https:\/\/www.seimc.org\/contenidos\/congresosyeventos\/seimcanteriores\/seimc-EIMC-2006.pdf<\/ext-link> Cited 5 August 2018"},{"issue":"10","key":"ref39","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1157\/13079773","article-title":"<italic>Strongyloides stercolaris<\/italic> y asma bronquial","volume":"205","author":"J Lozano Polo","year":"2005","journal-title":"Rev Clin Esp"},{"key":"ref40","first-page":"212","article-title":"Infestaci\u00f3n en la comarca de la Safor","volume":"109","author":"IA Cremades Romero","year":"1997","journal-title":"Med Clin (Barc)"},{"key":"ref41","first-page":"125","article-title":"Infestaci\u00f3n grave por Estrongiloides, s\u00edndrome paraneopl\u00e1sico","volume":"30","author":"V Sanchis-Bayarri","year":"1981","journal-title":"Rev Diagn Biol"},{"issue":"8","key":"ref42","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0213-005X(02)72827-9","article-title":"Insuficiencia respiratoria y renal en paciente con enfermedad pulmonar obstructiva cr\u00f3nica en tratamiento con corticoides.","volume":"20","author":"MD Tirado","year":"2002","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"ref43","first-page":"326","article-title":"Diarrea y eosinofilia en paciente con asma bronquial","volume":"14","author":"O Nevado","year":"1996","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"2","key":"ref44","first-page":"217","article-title":"Estrongiloidiasis en paciente inmunodeprimido","volume":"73","author":"A Sampedro","year":"1988","journal-title":"Rev Esp Enf Ap Digest"},{"key":"ref45","first-page":"273","article-title":"<italic>Strongyloides stercoralis<\/italic> y colitis ulcerosa","volume":"15","author":"A Lopez Gallardo","year":"1997","journal-title":"Enferm Infecc Microbiol Clin"},{"key":"ref46","first-page":"375","article-title":"Eosinofilia en un paciente bronquitico cr\u00f3nico","volume":"13","author":"M Toldos","year":"1995","journal-title":"Enferm Infecc Microbiol Clin"},{"issue":"2","key":"ref47","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003482","article-title":"Is Strongyloidiasis Endemic in Spain?","volume":"9","author":"A Mart\u00ednez-P\u00e9rez","year":"2015","journal-title":"PLoS Neg Trop Dis"},{"issue":"1","key":"ref48","doi-asserted-by":"crossref","first-page":"e2002","DOI":"10.1371\/journal.pntd.0002002","article-title":"The laboratory diagnosis and follow up of strongyloidiasis: a systematic review","volume":"7","author":"A Requena-Mendez","year":"2013","journal-title":"PLoS Negl Trop Dis"}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pntd.0007230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T14:05:23Z","timestamp":1589033123000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0007230"}},"subtitle":[],"editor":[{"given":"Aysegul","family":"Taylan Ozkan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,3,12]]},"references-count":48,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,3,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0007230","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,12]]}}}