{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:38:01Z","timestamp":1792532281306,"version":"4.5.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0008424","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T00:00:00Z","timestamp":1597276800000}}],"reference-count":95,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T00:00:00Z","timestamp":1596412800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2014\/03620-2; 2018\/23693-5"],"award-info":[{"award-number":["2014\/03620-2; 2018\/23693-5"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2013\/08028-1; 14\/50931-3"],"award-info":[{"award-number":["2013\/08028-1; 14\/50931-3"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["465355\/2014-5"],"award-info":[{"award-number":["465355\/2014-5"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["Finance Code 001"],"award-info":[{"award-number":["Finance Code 001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2017\/16283-2"],"award-info":[{"award-number":["2017\/16283-2"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/18469-1"],"award-info":[{"award-number":["2019\/18469-1"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005942","name":"Funda\u00e7\u00e3o Butantan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005942","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0008424","type":"journal-article","created":{"date-parts":[[2020,8,3]],"date-time":"2020-08-03T13:43:46Z","timestamp":1596462226000},"page":"e0008424","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":27,"title":["Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4999-5099","authenticated-orcid":true,"given":"Murilo Sena","family":"Amaral","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9526-8701","authenticated-orcid":true,"given":"Ernesto","family":"Goulart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1735-2008","authenticated-orcid":true,"given":"Luiz Carlos","family":"Caires-J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Abraham","family":"Morales-Vicente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6514-8458","authenticated-orcid":true,"given":"Alessandra","family":"Soares-Schanoski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roselane Paiva","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna Gon\u00e7alves de Oliveira","family":"Olberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato Mancini","family":"Astray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge E.","family":"Kalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayana","family":"Zatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6356-2401","authenticated-orcid":true,"given":"Sergio","family":"Verjovski-Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,8,3]]},"reference":[{"key":"pntd.0008424.ref001","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1056\/NEJMoa0805715","article-title":"Zika virus outbreak on Yap Island, Federated States of Micronesia","volume":"360","author":"MR Duffy","year":"2009","journal-title":"N Engl J Med"},{"key":"pntd.0008424.ref002","first-page":"1085","article-title":"Zika virus, French polynesia, South pacific, 2013","volume":"20","author":"VM Cao-Lormeau","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"pntd.0008424.ref003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJMp1605367","article-title":"Zika and the Risk of Microcephaly","volume":"375","author":"MA Johansson","year":"2016","journal-title":"N Engl J Med"},{"key":"pntd.0008424.ref004","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/nature22365","article-title":"Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes","volume":"545","author":"Y Liu","year":"2017","journal-title":"Nature"},{"key":"pntd.0008424.ref005","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1126\/science.aam7120","article-title":"A single mutation in the prM protein of Zika virus contributes to fetal microcephaly","volume":"358","author":"L Yuan","year":"2017","journal-title":"Science"},{"key":"pntd.0008424.ref006","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.tim.2018.05.007","article-title":"Did Zika Virus Mutate to Cause Severe Outbreaks?","volume":"26","author":"SL Rossi","year":"2018","journal-title":"Trends Microbiol"},{"key":"pntd.0008424.ref007","article-title":"Zika virus infection: an update","author":"P Ferraris","year":"2019","journal-title":"Microbes Infect"},{"key":"pntd.0008424.ref008","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/s41586-018-0446-y","article-title":"The emergence of Zika virus and its new clinical syndromes","volume":"560","author":"TC Pierson","year":"2018","journal-title":"Nature"},{"key":"pntd.0008424.ref009","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S1473-3099(16)30015-9","article-title":"Microcephaly in Brazil: confidence builds in Zika connection","volume":"16","author":"M Triunfol","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"pntd.0008424.ref010","doi-asserted-by":"crossref","first-page":"59","DOI":"10.15585\/mmwr.mm6503e2","article-title":"Possible Association Between Zika Virus Infection and Microcephaly\u2014Brazil, 2015","volume":"65","author":"L Schuler-Faccini","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"pntd.0008424.ref011","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s00401-017-1699-5","article-title":"The spectrum of neuropathological changes associated with congenital Zika virus infection","volume":"133","author":"L Chimelli","year":"2017","journal-title":"Acta Neuropathol"},{"key":"pntd.0008424.ref012","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/ajmg.a.38170","article-title":"The phenotypic spectrum of congenital Zika syndrome","volume":"173","author":"M Del Campo","year":"2017","journal-title":"Am J Med Genet A"},{"key":"pntd.0008424.ref013","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1016\/S0140-6736(16)30902-3","article-title":"Congenital Zika virus syndrome in Brazil: a case series of the first 1501 livebirths with complete investigation","volume":"388","author":"GV Franca","year":"2016","journal-title":"Lancet"},{"key":"pntd.0008424.ref014","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1101\/gad.298216.117","article-title":"How does Zika virus cause microcephaly?","volume":"31","author":"Z Wen","year":"2017","journal-title":"Genes Dev"},{"key":"pntd.0008424.ref015","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1056\/NEJMsr1604338","article-title":"Zika Virus and Birth Defects\u2014Reviewing the Evidence for Causality","volume":"374","author":"SA Rasmussen","year":"2016","journal-title":"N Engl J Med"},{"key":"pntd.0008424.ref016","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1056\/NEJMoa1600651","article-title":"Zika Virus Associated with Microcephaly","volume":"374","author":"J Mlakar","year":"2016","journal-title":"N Engl J Med"},{"key":"pntd.0008424.ref017","doi-asserted-by":"crossref","first-page":"4160","DOI":"10.1007\/s12035-017-0635-y","article-title":"Zika Virus as an Emerging Neuropathogen: Mechanisms of Neurovirulence and Neuro-Immune Interactions","volume":"55","author":"G Morris","year":"2018","journal-title":"Mol Neurobiol"},{"key":"pntd.0008424.ref018","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.neuron.2016.11.031","article-title":"The Neurobiology of Zika Virus","volume":"92","author":"H Li","year":"2016","journal-title":"Neuron"},{"key":"pntd.0008424.ref019","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.chom.2017.01.004","article-title":"Zika Virus Pathogenesis and Tissue Tropism","volume":"21","author":"JJ Miner","year":"2017","journal-title":"Cell Host Microbe"},{"key":"pntd.0008424.ref020","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1146\/annurev-neuro-080317-062231","article-title":"Pathophysiology and Mechanisms of Zika Virus Infection in the Nervous System","volume":"42","author":"KM Christian","year":"2019","journal-title":"Annu Rev Neurosci"},{"key":"pntd.0008424.ref021","doi-asserted-by":"crossref","first-page":"3890","DOI":"10.1038\/s41467-019-11866-7","article-title":"Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice","volume":"10","author":"CP Figueiredo","year":"2019","journal-title":"Nat Commun"},{"key":"pntd.0008424.ref022","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1038\/emi.2017.9","article-title":"Zika virus infection reprograms global transcription of host cells to allow sustained infection","volume":"6","author":"SK Tiwari","year":"2017","journal-title":"Emerg Microbes Infect"},{"key":"pntd.0008424.ref023","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.chom.2017.04.007","article-title":"Microbial Vertical Transmission during Human Pregnancy","volume":"21","author":"N Arora","year":"2017","journal-title":"Cell Host Microbe"},{"key":"pntd.0008424.ref024","first-page":"1465","volume":"10","author":"SF Khaiboullina","year":"2019","journal-title":"Zika Virus Transmission Through Blood Tissue Barriers"},{"key":"pntd.0008424.ref025","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.chom.2016.03.008","article-title":"Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection","volume":"19","author":"A Bayer","year":"2016","journal-title":"Cell Host Microbe"},{"key":"pntd.0008424.ref026","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.chom.2016.07.002","article-title":"Zika Virus Targets Different Primary Human Placental Cells, Suggesting Two Routes for Vertical Transmission","volume":"20","author":"T Tabata","year":"2016","journal-title":"Cell Host Microbe"},{"key":"pntd.0008424.ref027","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.chom.2016.05.015","article-title":"Zika Virus Infects Human Placental Macrophages","volume":"20","author":"KM Quicke","year":"2016","journal-title":"Cell Host Microbe"},{"key":"pntd.0008424.ref028","doi-asserted-by":"crossref","first-page":"41389","DOI":"10.1038\/srep41389","article-title":"Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication","volume":"7","author":"KM Aagaard","year":"2017","journal-title":"Sci Rep"},{"key":"pntd.0008424.ref029","doi-asserted-by":"crossref","first-page":"e01905","DOI":"10.1128\/JVI.01905-16","article-title":"Zika Virus Infects Early- and Midgestation Human Maternal Decidual Tissues, Inducing Distinct Innate Tissue Responses in the Maternal-Fetal Interface","volume":"91","author":"Y Weisblum","year":"2017","journal-title":"J Virol"},{"key":"pntd.0008424.ref030","doi-asserted-by":"crossref","first-page":"2321","DOI":"10.1056\/NEJMoa1602412","article-title":"Zika Virus Infection in Pregnant Women in Rio de Janeiro","volume":"375","author":"P Brasil","year":"2016","journal-title":"N Engl J Med"},{"key":"pntd.0008424.ref031","doi-asserted-by":"crossref","first-page":"615","DOI":"10.15585\/mmwr.mm6623e1","article-title":"Pregnancy Outcomes After Maternal Zika Virus Infection During Pregnancy\u2014U.S. Territories, January 1, 2016-April 25, 2017","volume":"66","author":"CK Shapiro-Mendoza","year":"2017","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"pntd.0008424.ref032","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/s41467-017-02790-9","article-title":"Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells","volume":"9","author":"LC Caires-Junior","year":"2018","journal-title":"Nat Commun"},{"key":"pntd.0008424.ref033","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.stemcr.2017.01.008","article-title":"Differential Responses of Human Fetal Brain Neural Stem Cells to Zika Virus Infection","volume":"8","author":"EL McGrath","year":"2017","journal-title":"Stem Cell Reports"},{"key":"pntd.0008424.ref034","article-title":"Discordant Zika virus findings in twin pregnancies complicated by antenatal Zika virus exposure: a prospective cohort","author":"NC Sobhani","year":"2019","journal-title":"J Infect Dis:"},{"key":"pntd.0008424.ref035","doi-asserted-by":"crossref","first-page":"E1212","DOI":"10.1073\/pnas.1303094110","article-title":"Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4","volume":"110","author":"M Amita","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"pntd.0008424.ref036","doi-asserted-by":"crossref","first-page":"E1587","DOI":"10.1073\/pnas.1616097114","article-title":"Vulnerability of primitive human placental trophoblast to Zika virus","volume":"114","author":"MA Sheridan","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"pntd.0008424.ref037","doi-asserted-by":"crossref","first-page":"e1158","DOI":"10.1542\/peds.2011-3846","article-title":"New reference curves for head circumference at birth, by gestational age","volume":"131","author":"A Barbier","year":"2013","journal-title":"Pediatrics"},{"key":"pntd.0008424.ref038","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1126\/science.aaf5036","article-title":"Zika virus in the Americas: Early epidemiological and genetic findings","volume":"352","author":"NR Faria","year":"2016","journal-title":"Science"},{"key":"pntd.0008424.ref039","doi-asserted-by":"crossref","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","article-title":"fastp: an ultra-fast all-in-one FASTQ preprocessor","volume":"34","author":"S Chen","year":"2018","journal-title":"Bioinformatics"},{"key":"pntd.0008424.ref040","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1186\/1471-2105-12-323","article-title":"RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome","volume":"12","author":"B Li","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"pntd.0008424.ref041","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"A Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"pntd.0008424.ref042","doi-asserted-by":"crossref","first-page":"D766","DOI":"10.1093\/nar\/gky955","article-title":"GENCODE reference annotation for the human and mouse genomes","volume":"47","author":"A Frankish","year":"2018","journal-title":"Nucleic Acids Research"},{"key":"pntd.0008424.ref043","doi-asserted-by":"crossref","first-page":"4288","DOI":"10.1093\/nar\/gks042","article-title":"Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation","volume":"40","author":"DJ McCarthy","year":"2012","journal-title":"Nucleic Acids Research"},{"key":"pntd.0008424.ref044","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1101\/gr.131508.111","article-title":"Cooperation between Polycomb and androgen receptor during oncogenic transformation","volume":"22","author":"JC Zhao","year":"2012","journal-title":"Genome Res"},{"key":"pntd.0008424.ref045","first-page":"257","article-title":"What Is Trophoblast?","volume":"6","author":"CQ Lee","year":"2016","journal-title":"A Combination of Criteria Define Human First-Trimester Trophoblast. Stem Cell Reports"},{"key":"pntd.0008424.ref046","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1095\/biolreprod.110.088724","article-title":"Trophoblast stem cells","volume":"84","author":"RM Roberts","year":"2011","journal-title":"Biol Reprod"},{"key":"pntd.0008424.ref047","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3390\/v6010069","article-title":"Flavivirus entry receptors: an update","volume":"6","author":"M Perera-Lecoin","year":"2013","journal-title":"Viruses"},{"key":"pntd.0008424.ref048","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3390\/v10050233","article-title":"Probing Molecular Insights into Zika Virus(-)Host Interactions","volume":"10","author":"I Lee","year":"2018","journal-title":"Viruses"},{"key":"pntd.0008424.ref049","doi-asserted-by":"crossref","first-page":"8880","DOI":"10.1128\/JVI.00354-15","article-title":"Biology of Zika Virus Infection in Human Skin Cells","volume":"89","author":"R Hamel","year":"2015","journal-title":"J Virol"},{"key":"pntd.0008424.ref050","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.stem.2016.03.012","article-title":"Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells","volume":"18","author":"TJ Nowakowski","year":"2016","journal-title":"Cell Stem Cell"},{"key":"pntd.0008424.ref051","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1073\/pnas.1620558114","article-title":"AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses","volume":"114","author":"AS Richard","year":"2017","journal-title":"Proc Natl Acad Sci U S A"},{"key":"pntd.0008424.ref052","doi-asserted-by":"crossref","first-page":"e0208543","DOI":"10.1371\/journal.pone.0208543","article-title":"Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes","volume":"14","author":"CR Ojha","year":"2019","journal-title":"PLoS One"},{"key":"pntd.0008424.ref053","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01372-19","article-title":"Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells","volume":"10","author":"DP Strange","year":"2019","journal-title":"MBio"},{"key":"pntd.0008424.ref054","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/0092-8674(95)90520-0","article-title":"The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3\/Axl family of receptor tyrosine kinases","volume":"80","author":"TN Stitt","year":"1995","journal-title":"Cell"},{"key":"pntd.0008424.ref055","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.cyto.2019.02.009","article-title":"Running interference: Interplay between Zika virus and the host interferon response","volume":"119","author":"RD Pardy","year":"2019","journal-title":"Cytokine"},{"key":"pntd.0008424.ref056","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/s41467-018-07993-2","article-title":"Interferon lambda protects the female reproductive tract against Zika virus infection","volume":"10","author":"EA Caine","year":"2019","journal-title":"Nat Commun"},{"key":"pntd.0008424.ref057","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.immuni.2018.07.017","article-title":"Interferons and Proinflammatory Cytokines in Pregnancy and Fetal Development","volume":"49","author":"LJ Yockey","year":"2018","journal-title":"Immunity"},{"key":"pntd.0008424.ref058","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aat6114","article-title":"Immune responses at the maternal-fetal interface","volume":"4","author":"SE Ander","year":"2019","journal-title":"Sci Immunol"},{"key":"pntd.0008424.ref059","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/cr.2016.58","article-title":"Vertical transmission of Zika virus targeting the radial glial cells affects cortex development of offspring mice","volume":"26","author":"KY Wu","year":"2016","journal-title":"Cell Res"},{"key":"pntd.0008424.ref060","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.cell.2016.05.008","article-title":"Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise","volume":"165","author":"JJ Miner","year":"2016","journal-title":"Cell"},{"key":"pntd.0008424.ref061","doi-asserted-by":"crossref","first-page":"e1006219","DOI":"10.1371\/journal.ppat.1006219","article-title":"Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues","volume":"13","author":"AJ Hirsch","year":"2017","journal-title":"PLoS Pathog"},{"key":"pntd.0008424.ref062","doi-asserted-by":"crossref","first-page":"12204","DOI":"10.1038\/ncomms12204","article-title":"A rhesus macaque model of Asian-lineage Zika virus infection","volume":"7","author":"DM Dudley","year":"2016","journal-title":"Nat Commun"},{"key":"pntd.0008424.ref063","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.stem.2016.02.016","article-title":"Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth","volume":"18","author":"H Tang","year":"2016","journal-title":"Cell Stem Cell"},{"key":"pntd.0008424.ref064","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.jid.2018.07.038","article-title":"Insights into ZIKV-Mediated Innate Immune Responses in Human Dermal Fibroblasts and Epidermal Keratinocytes","volume":"139","author":"JA Kim","year":"2019","journal-title":"J Invest Dermatol"},{"key":"pntd.0008424.ref065","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.3390\/ijms20051101","article-title":"Advances in Zika Virus(-)Host Cell Interaction: Current Knowledge and Future Perspectives","volume":"20","author":"JK Lee","year":"2019","journal-title":"Int J Mol Sci"},{"key":"pntd.0008424.ref066","doi-asserted-by":"crossref","first-page":"e1002611","DOI":"10.1371\/journal.pmed.1002611","article-title":"Sexual transmission of Zika virus and other flaviviruses: A living systematic review","volume":"15","author":"MJ Counotte","year":"2018","journal-title":"PLoS Med"},{"key":"pntd.0008424.ref067","doi-asserted-by":"crossref","first-page":"35296","DOI":"10.1038\/srep35296","article-title":"ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy","volume":"6","author":"H El Costa","year":"2016","journal-title":"Sci Rep"},{"key":"pntd.0008424.ref068","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3201\/eid1705.101939","article-title":"Probable non-vector-borne transmission of Zika virus, Colorado, USA","volume":"17","author":"BD Foy","year":"2011","journal-title":"Emerg Infect Dis"},{"key":"pntd.0008424.ref069","doi-asserted-by":"crossref","first-page":"2195","DOI":"10.1056\/NEJMc1604449","article-title":"Evidence of Sexual Transmission of Zika Virus","volume":"374","author":"E D'Ortenzio","year":"2016","journal-title":"N Engl J Med"},{"key":"pntd.0008424.ref070","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1473-3099(16)00095-5","article-title":"Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study","volume":"16","author":"G Calvet","year":"2016","journal-title":"Lancet Infect Dis"},{"key":"pntd.0008424.ref071","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1038\/s41467-019-12063-2","article-title":"Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells","volume":"10","author":"L Tan","year":"2019","journal-title":"Nat Commun"},{"key":"pntd.0008424.ref072","doi-asserted-by":"crossref","first-page":"44286","DOI":"10.1038\/srep44286","article-title":"Human Endometrial Stromal Cells Are Highly Permissive To Productive Infection by Zika Virus","volume":"7","author":"I Pagani","year":"2017","journal-title":"Sci Rep"},{"key":"pntd.0008424.ref073","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.it.2018.08.008","article-title":"Type III Interferons in Antiviral Defenses at Barrier Surfaces","volume":"39","author":"AI Wells","year":"2018","journal-title":"Trends Immunol"},{"key":"pntd.0008424.ref074","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1016\/j.celrep.2017.10.059","article-title":"Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action","volume":"21","author":"J Chen","year":"2017","journal-title":"Cell Rep"},{"key":"pntd.0008424.ref075","doi-asserted-by":"crossref","first-page":"3945","DOI":"10.4049\/jimmunol.0990015","article-title":"The unexpected pleiotropic activities of RANTES","volume":"182","author":"JA Levy","year":"2009","journal-title":"J Immunol"},{"key":"pntd.0008424.ref076","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S1471-4906(00)01812-3","article-title":"RANTES: a versatile and controversial chemokine","volume":"22","author":"V Appay","year":"2001","journal-title":"Trends Immunol"},{"key":"pntd.0008424.ref077","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1159\/000357780","article-title":"The biological functions, structure and sources of CXCL10 and its outstanding part in the pathophysiology of multiple sclerosis","volume":"21","author":"R Vazirinejad","year":"2014","journal-title":"Neuroimmunomodulation"},{"key":"pntd.0008424.ref078","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/molehr\/6.3.246","article-title":"Effects of lipopolysaccharide and cytokines on production of RANTES by cultured human endometrial stromal cells","volume":"6","author":"K Arima","year":"2000","journal-title":"Mol Hum Reprod"},{"key":"pntd.0008424.ref079","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.bbapap.2005.04.007","article-title":"Regulation of human extravillous trophoblast function by membrane-bound peptidases","volume":"1751","author":"H Fujiwara","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"pntd.0008424.ref080","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1034\/j.1600-0897.2002.01075.x","article-title":"Uterine chemokines in reproductive physiology and pathology","volume":"47","author":"UA Kayisli","year":"2002","journal-title":"Am J Reprod Immunol"},{"key":"pntd.0008424.ref081","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/molehr\/gan032","article-title":"CXCL10 and IL-6 induce chemotaxis in human trophoblast cell lines","volume":"14","author":"F Dominguez","year":"2008","journal-title":"Mol Hum Reprod"},{"key":"pntd.0008424.ref082","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1089\/jir.2017.0011","article-title":"Maternal-Fetal Transmission of Zika Virus: Routes and Signals for Infection","volume":"37","author":"B Cao","year":"2017","journal-title":"J Interferon Cytokine Res"},{"key":"pntd.0008424.ref083","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1172\/JCI200422991","article-title":"Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface","volume":"114","author":"K Red-Horse","year":"2004","journal-title":"J Clin Invest"},{"key":"pntd.0008424.ref084","doi-asserted-by":"crossref","first-page":"e28514","DOI":"10.1371\/journal.pone.0028514","article-title":"Galectin-1 is part of human trophoblast invasion machinery\u2014a functional study in vitro","volume":"6","author":"N Kolundzic","year":"2011","journal-title":"PLoS One"},{"key":"pntd.0008424.ref085","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.placenta.2011.07.087","article-title":"Galectin-8 is expressed by villous and extravillous trophoblast of the human placenta","volume":"32","author":"N Kolundzic","year":"2011","journal-title":"Placenta"},{"key":"pntd.0008424.ref086","doi-asserted-by":"crossref","first-page":"578","DOI":"10.3109\/01443615.2014.990430","article-title":"Analysis of gene expression identifies candidate markers and pathways in pre-eclampsia","volume":"35","author":"P He","year":"2015","journal-title":"J Obstet Gynaecol"},{"key":"pntd.0008424.ref087","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4239\/wjd.v2.i11.196","article-title":"Consequences of gestational and pregestational diabetes on placental function and birth weight","volume":"2","author":"A Vambergue","year":"2011","journal-title":"World J Diabetes"},{"key":"pntd.0008424.ref088","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1095\/biolreprod56.2.348","article-title":"Distribution of integrins and the extracellular matrix proteins in the baboon endometrium during the menstrual cycle and early pregnancy","volume":"56","author":"AT Fazleabas","year":"1997","journal-title":"Biol Reprod"},{"key":"pntd.0008424.ref089","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1172\/JCI115565","article-title":"Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo","volume":"89","author":"CH Damsky","year":"1992","journal-title":"J Clin Invest"},{"key":"pntd.0008424.ref090","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1172\/JCI116316","article-title":"Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts","volume":"91","author":"Y Zhou","year":"1993","journal-title":"J Clin Invest"},{"key":"pntd.0008424.ref091","doi-asserted-by":"crossref","first-page":"e0156038","DOI":"10.1371\/journal.pone.0156038","article-title":"Differential Expression of Extracellular Matrix and Adhesion Molecules in Fetal-Origin Amniotic Epithelial Cells of Preeclamptic Pregnancy","volume":"11","author":"MS Kim","year":"2016","journal-title":"PLoS One"},{"key":"pntd.0008424.ref092","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1038\/s41598-018-38374-w","article-title":"Human trophoblast requires galectin-3 for cell migration and invasion","volume":"9","author":"Z Bojic-Trbojevic","year":"2019","journal-title":"Sci Rep"},{"key":"pntd.0008424.ref093","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3390\/ijms17040523","article-title":"Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR)","volume":"17","author":"S Hutter","year":"2016","journal-title":"Int J Mol Sci"},{"key":"pntd.0008424.ref094","doi-asserted-by":"crossref","first-page":"7753","DOI":"10.1093\/nar\/gkt567","article-title":"LHX2 regulates the neural differentiation of human embryonic stem cells via transcriptional modulation of PAX6 and CER1","volume":"41","author":"PS Hou","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"pntd.0008424.ref095","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/dgd.12367","article-title":"Evolutionary conservation and conversion of Foxg1 function in brain development","volume":"59","author":"T Kumamoto","year":"2017","journal-title":"Dev Growth Differ"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0008424","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T00:00:00Z","timestamp":1597276800000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0008424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T15:11:38Z","timestamp":1597331498000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0008424"}},"subtitle":[],"editor":[{"given":"Kristy O.","family":"Murray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,8,3]]},"references-count":95,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0008424","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/867465","asserted-by":"object"}]},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,3]]}}}