{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T11:07:10Z","timestamp":1767179230527,"version":"build-2238731810"},"update-to":[{"DOI":"10.1371\/journal.pntd.0008500","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T00:00:00Z","timestamp":1597795200000}}],"reference-count":48,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T00:00:00Z","timestamp":1596067200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0008500","type":"journal-article","created":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T18:54:20Z","timestamp":1596135260000},"page":"e0008500","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["A new diagnostic strategy which uses a luminol-H2O2 system to detect helminth eggs in fecal sediments processed by the Helmintex method"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5145-4606","authenticated-orcid":true,"given":"Vivian","family":"Favero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina De Marco","family":"Ver\u00edssimo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela R.","family":"Piovesan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra L.","family":"Morassutti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9 A.","family":"Souto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9lio R.","family":"Bittencourt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa F.","family":"Pascoal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catieli G.","family":"Lindholz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0035-6141","authenticated-orcid":true,"given":"Malcolm K.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renata P.","family":"Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francine De Vargas","family":"Rigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9lia R.","family":"Carlini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Graeff-Teixeira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2020,7,30]]},"reference":[{"issue":"4","key":"pntd.0008500.ref001","doi-asserted-by":"crossref","first-page":"e1601","DOI":"10.1371\/journal.pntd.0001601","article-title":"A research agenda for helminth diseases of humans: diagnostics for control and elimination programmes","volume":"6","author":"JS McCarthy","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"issue":"2","key":"pntd.0008500.ref002","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.actatropica.2012.04.013","article-title":"Time to set the agenda for schistosomiasis elimination","volume":"128","author":"D Rollinson","year":"2013","journal-title":"Acta Trop"},{"key":"pntd.0008500.ref003","first-page":"7","article-title":"Schistosomiasis","volume":"4","author":"P McManus","year":"2018","journal-title":"Nat"},{"issue":"1623","key":"pntd.0008500.ref004","doi-asserted-by":"crossref","first-page":"20120144","DOI":"10.1098\/rstb.2012.0144","article-title":"Preventive chemotherapy as a strategy for elimination of neglected tropical parasitic diseases: endgame challenges","volume":"368","author":"MJ Bockarie","year":"2013","journal-title":"Phil. Trans. R. Soc. B"},{"issue":"9541","key":"pntd.0008500.ref005","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/S0140-6736(06)69440-3","article-title":"Human schistosomiasis","volume":"368","author":"B Gryseels","year":"2006","journal-title":"Lancet"},{"issue":"9936","key":"pntd.0008500.ref006","doi-asserted-by":"crossref","first-page":"2253","DOI":"10.1016\/S0140-6736(13)61949-2","article-title":"Human schistosomiasis","volume":"383","author":"DG Colley","year":"2014","journal-title":"Lancet"},{"issue":"2","key":"pntd.0008500.ref007","doi-asserted-by":"crossref","first-page":"e64","DOI":"10.1016\/S1473-3099(16)30535-7","article-title":"A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now","volume":"17","author":"NC Lo","year":"2017","journal-title":"Lancet Infect Dis"},{"issue":"4","key":"pntd.0008500.ref008","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.pt.2009.01.004","article-title":"Diagnostic dilemmas in helminthology: what tools to use and when?","volume":"25","author":"R Bergquist","year":"2009","journal-title":"Trends Parasit"},{"issue":"2","key":"pntd.0008500.ref009","doi-asserted-by":"crossref","first-page":"157","DOI":"10.4269\/ajtmh.2002.66.157","article-title":"Detection by polymerase chain reaction of Schistosoma mansoni DNA in human serum and feces","volume":"66","author":"LA Pontes","year":"2002","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"pntd.0008500.ref010","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.exppara.2006.02.012","article-title":"Schistosoma mansoni: a diagnostic approach to detect acute schistosomiasis infection in a murine model by PCR","volume":"114","author":"N Sandoval","year":"2006","journal-title":"Exp. Parasitol"},{"issue":"4","key":"pntd.0008500.ref011","first-page":"233","article-title":"Quantitative diagnosis of Schistosoma infections by measurement of circulating antigens in serum and urine","volume":"46","author":"AM Deelder","year":"1994","journal-title":"Trop Geogr Med"},{"issue":"7","key":"pntd.0008500.ref012","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1046\/j.1365-3156.1997.d01-354.x","article-title":"Circulating anodic and cathodic antigen in serum and urine of mixed Schistosoma haematobium and S. mansoni infections in Office du Niger, Mali","volume":"2","author":"D De Clercq","year":"1997","journal-title":"Trop Med Int Health"},{"issue":"2","key":"pntd.0008500.ref013","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/S0035-9203(97)90233-9","article-title":"Daily fluctuation of levels of circulating cathodic antigen in urine of children infected with Schistosoma mansoni in Brazil","volume":"91","author":"J Disch","year":"1997","journal-title":"Tans R Soc Trop Med Hyg"},{"issue":"1","key":"pntd.0008500.ref014","doi-asserted-by":"crossref","first-page":"150","DOI":"10.4269\/ajtmh.1998.59.150","article-title":"Day-to-day fluctuation of schistosome circulating antigen levels in serum and urine of humans infected with Schistosoma mansoni in Burundi","volume":"59","author":"K Polman","year":"1998","journal-title":"Am J Trop Med Hyg"},{"issue":"6","key":"pntd.0008500.ref015","first-page":"397","article-title":"A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni","volume":"14","author":"N Katz","year":"1972","journal-title":"Rev Inst Med Trop Sao Paulo"},{"issue":"5","key":"pntd.0008500.ref016","doi-asserted-by":"crossref","first-page":"787","DOI":"10.4269\/ajtmh.2011.10-0685","article-title":"Schistosomiasis among young children in Usoma, Kenya","volume":"84","author":"JR Verani","year":"2011","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"pntd.0008500.ref017","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.inhe.2010.02.003","article-title":"Treatment of intestinal schistosomiasis in Ugandan preschool children: best diagnosis, treatment efficacy and side-effects, and an extended praziquantel dosing pole","volume":"2","author":"JC Sousa-Figueiredo","year":"2010","journal-title":"Int Health"},{"issue":"1","key":"pntd.0008500.ref018","doi-asserted-by":"crossref","first-page":"e938","DOI":"10.1371\/journal.pntd.0000938","article-title":"Schistosoma mansoni infections in young children: when are schistosome antigens in urine, eggs in stool and antibodies to eggs first detectable?","volume":"5","author":"JR Stothard","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"pntd.0008500.ref019","doi-asserted-by":"crossref","first-page":"e2109","DOI":"10.1371\/journal.pntd.0002109","article-title":"Accuracy of urine circulating cathodic antigen test for the diagnosis of Schistosoma mansoni in preschool-aged children before and after treatment","volume":"7","author":"JT Coulibaly","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"pntd.0008500.ref020","doi-asserted-by":"crossref","first-page":"e951","DOI":"10.1371\/journal.pntd.0000951","article-title":"Evaluation of urine CCA assays for detection of Schistosoma mansoni infection in Western Kenya","volume":"5","author":"HL Shane","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"pntd.0008500.ref021","doi-asserted-by":"crossref","first-page":"e0006274","DOI":"10.1371\/journal.pntd.0006274","article-title":"Study of diagnostic accuracy of Helmintex, Kato-Katz, and POC-CCA methods for diagnosing intestinal schistosomiasis in Candeal, a low intensity transmission area in northeastern Brazil","volume":"12","author":"CG Lindholz","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"pntd.0008500.ref022","doi-asserted-by":"crossref","first-page":"664","DOI":"10.4269\/ajtmh.16-0671","article-title":"Countrywide reassessment of Schistosoma mansoni infection in Burundi using a urine-circulating cathodic antigen rapid test: informing the national control program","volume":"96","author":"G Ortu","year":"2017","journal-title":"Am J Trop Med Hyg"},{"issue":"2","key":"pntd.0008500.ref023","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1371\/journal.pntd.0000073","article-title":"Detection of Schistosoma mansoni eggs in feces through their interaction with paramagnetic beads in a magnetic field","volume":"1","author":"CF Teixeira","year":"2007","journal-title":"PLoS Negl Trop Dis"},{"key":"pntd.0008500.ref024","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.exppara.2017.04.001","article-title":"Optimization of the Helmintex method for schistosomiasis diagnosis","volume":"177","author":"V Favero","year":"2017","journal-title":"Exp Parasitol"},{"issue":"1","key":"pntd.0008500.ref025","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1186\/s13071-019-3403-1","article-title":"Qualitative and quantitative proteomic analyses of Schistosoma japonicum eggs and egg-derived secretory-excretory proteins","volume":"12","author":"CM Verissimo","journal-title":"Parasit Vectors"},{"issue":"2","key":"pntd.0008500.ref026","doi-asserted-by":"crossref","first-page":"e0006232","DOI":"10.1371\/journal.pntd.0006232","article-title":"Evaluation of diagnostic methods for the detection of intestinal schistosomiasis in endemic areas with low parasite loads: Saline gradient, Helmintex, Kato-Katz and rapid urine test","volume":"2","author":"WJ Oliveira","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"pntd.0008500.ref027","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1017\/S0031182097001091","article-title":"A method for the isolation of schistosome eggs and miracidia free of contaminating host tissues","volume":"115","author":"J Dalton","year":"1997","journal-title":"Parasitol"},{"issue":"12","key":"pntd.0008500.ref028","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1021\/ac00108a035","article-title":"Chemiluminescence and Bioluminescence","volume":"67","author":"Larry J. Kricka","year":"1995","journal-title":"Anal. Chemi"},{"issue":"7","key":"pntd.0008500.ref029","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1002\/andp.18882700703","article-title":"Ueber Fluorescenz und Phosphorescenz I. Abhandlung","volume":"270","author":"E. Wiedemann","year":"1888","journal-title":"Annalen der Physik"},{"issue":"2","key":"pntd.0008500.ref030","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s12010-014-0850-1","article-title":"Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses","volume":"173","author":"P Khan","year":"2014","journal-title":"Appl Biochem Biotechnol"},{"issue":"6","key":"pntd.0008500.ref031","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1590\/S0100-40421998000600018","article-title":"Quimiluminesc\u00eancia org\u00e2nica: alguns experimentos de demonstra\u00e7\u00e3o para a sala de aula","volume":"21","author":"R Albertin","year":"1998","journal-title":"Qu\u00edm Nova"},{"issue":"38","key":"pntd.0008500.ref032","doi-asserted-by":"crossref","first-page":"33159","DOI":"10.1021\/acsami.7b10325","article-title":"Influence of Luminol Doping of Poly (o-phenylenediamine) on the Spectral, Morphological, and Fluorescent properties: A Potential Fluorescent Marker for Early detection and Diagnosis of Leishmania donovani","volume":"9","author":"U Riaz","year":"2017","journal-title":"ACS Appl Mater Interfaces"},{"issue":"3","key":"pntd.0008500.ref033","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.talanta.2006.12.045","article-title":"Forensic application of the luminol reaction as a presumptive test for latent blood detection","volume":"72","author":"F Barni","year":"2007","journal-title":"Talanta"},{"issue":"1\u20133","key":"pntd.0008500.ref034","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0003-2670(97)00155-4","article-title":"Sequential response surface methodology for multioptimization in analytical chemistry with three-variable Doehlert designs","volume":"348","author":"AG Campa\u00f1a","year":"1997","journal-title":"Anal Chim Acta"},{"issue":"10","key":"pntd.0008500.ref035","doi-asserted-by":"crossref","first-page":"1975","DOI":"10.1021\/ac981357c","article-title":"Determination of subnanomolar levels of hydrogen peroxide in seawater by reagent-injection chemiluminescence detection","volume":"71","author":"J Yuan","year":"1999","journal-title":"Anal Chem"},{"issue":"6\u20137","key":"pntd.0008500.ref036","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1007\/s002160051569","article-title":"Bio-and chemiluminescence in bioanalysis","volume":"366","author":"A Roda","year":"2000","journal-title":"Fresenius J Anal Chem"},{"issue":"1\u20132","key":"pntd.0008500.ref037","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0021-9673(02)00004-3","article-title":"Luminol-type chemiluminescence derivatization reagents for liquid chromatography and capillary electrophoresis","volume":"950","author":"M Yamaguchi","year":"2002","journal-title":"J Chromat A"},{"issue":"7","key":"pntd.0008500.ref038","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1021\/ac951023c","article-title":"Chemiluminescence of luminol catalyzed by electrochemically oxidized ferrocenes","volume":"68","author":"R Wilson","year":"1996","journal-title":"Anal Chem"},{"issue":"7","key":"pntd.0008500.ref039","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1088\/0034-4885\/59\/7\/002","article-title":"Iron in biology: a structural viewpoint","volume":"59","author":"PF Lindley","year":"1996","journal-title":"Rep Prog Physics"},{"issue":"5","key":"pntd.0008500.ref040","doi-asserted-by":"crossref","first-page":"e2219","DOI":"10.1371\/journal.pntd.0002219","article-title":"The iron distribution and magnetic properties of schistosome eggshells: implications for improved diagnostics","volume":"7","author":"S Karl","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"issue":"5","key":"pntd.0008500.ref041","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.ijpara.2010.12.005","article-title":"The proteome of the insoluble Schistosoma mansoni eggshell skeleton","volume":"41","author":"S deWalick","year":"2011","journal-title":"Int J Parasitol"},{"issue":"5","key":"pntd.0008500.ref042","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.ijpara.2009.10.014","article-title":"A comparative proteomic study of the undeveloped and developed Schistosoma mansoni egg and its contents: the miracidium, hatch fluid and secretions","volume":"40","author":"W Mathieson","year":"2010","journal-title":"Int J Parasitol"},{"issue":"1","key":"pntd.0008500.ref043","doi-asserted-by":"crossref","first-page":"e0147247","DOI":"10.1371\/journal.pone.0147247","article-title":"Proteomic analysis of the Schistosoma mansoni miracidium","volume":"11","author":"T Wang","year":"2016","journal-title":"PloS one"},{"issue":"1","key":"pntd.0008500.ref044","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/s41564-018-0295-3","article-title":"REASSURED diagnostics to inform disease control strategies, strengthen health systems and improve patient outcomes","volume":"4","author":"K.J. Land","year":"2019","journal-title":"Nat Microbiol"},{"issue":"2","key":"pntd.0008500.ref045","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/ajcn\/69.2.250","article-title":"Oral ferrous sulfate supplements increase the free radical\u2013generating capacity of feces from healthy volunteers","volume":"69","author":"EK Lund","year":"1999","journal-title":"Am J Clin Nutr"},{"issue":"04","key":"pntd.0008500.ref046","first-page":"411","article-title":"Gastrointestinale Blutungen imfortgeschrittenen Lebensalter","volume":"139","author":"J. Glaser","year":"2014","journal-title":"Zentralbl Chir"},{"issue":"1","key":"pntd.0008500.ref047","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3122\/jabfm.2015.01.140153","article-title":"Diagnosis and management of upper gastrointestinal bleeding in children","volume":"28","author":"S Owensby","year":"2015","journal-title":"J Am Board Fam Med"},{"issue":"29","key":"pntd.0008500.ref048","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000011429","article-title":"Long-term follow up of patients with obscure gastrointestinal bleeding examined with video capsule endoscopy","volume":"97","author":"RJ Sealock","year":"2018","journal-title":"Medicine"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0008500","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T00:00:00Z","timestamp":1597795200000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0008500","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T22:54:03Z","timestamp":1723330443000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0008500"}},"subtitle":[],"editor":[{"given":"Gabriel","family":"Rinaldi","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2020,7,30]]},"references-count":48,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2020,7,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0008500","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,30]]}}}