{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:48:12Z","timestamp":1792788492528,"version":"4.5.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0008635","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000}}],"reference-count":72,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T00:00:00Z","timestamp":1598486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["480807\/2011-6"],"award-info":[{"award-number":["480807\/2011-6"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa de Minas Gerais","award":["APQ-01237-11"],"award-info":[{"award-number":["APQ-01237-11"]}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"crossref","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"DOI":"10.1371\/journal.pntd.0008635","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T13:54:13Z","timestamp":1598536453000},"page":"e0008635","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Liver damage in schistosomiasis is reduced by adipose tissue-derived stem cell therapy after praziquantel\u00a0treatment"],"prefix":"10.1371","volume":"14","author":[{"given":"Vitor Hugo Sim\u00f5es","family":"Miranda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talita Rocha","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirli Emerick","family":"Eller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena de C\u00e1ssia Neres","family":"Ferraz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Thereza","family":"Chaves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly Alves","family":"Bicalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Eduardo Calzavara","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Birbrair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Ant\u00f4nio","family":"Pascoal Xavier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo Miranda","family":"de Goes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Corr\u00eaa-Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c9rica Alessandra Rocha","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7126-0382","authenticated-orcid":true,"given":"Adriana","family":"Bozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"issue":"3","key":"pntd.0008635.ref001","doi-asserted-by":"crossref","first-page":"e0004493","DOI":"10.1371\/journal.pntd.0004493","article-title":"Schistosomiasis Prevalence and Intensity of Infection in Latin America and the Caribbean Countries, 1942\u20132014: A Systematic Review in the Context of a Regional Elimination Goal.","volume":"10","author":"AC Zoni","year":"2016","journal-title":"PLoS Negl Trop Dis."},{"key":"pntd.0008635.ref002","unstructured":"Schistosomiasis. WHO. 2017. doi: \/entity\/mediacentre\/factsheets\/fs115\/en\/index.html."},{"issue":"2","key":"pntd.0008635.ref003","doi-asserted-by":"crossref","first-page":"144","DOI":"10.7205\/MILMED.172.2.144","article-title":"Latent schistosomiasis in Portuguese soldiers.","volume":"172","author":"P Vieira","year":"2007","journal-title":"Mil Med"},{"issue":"3","key":"pntd.0008635.ref004","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1128\/IAI.54.3.820-826.1986","article-title":"Anti-L3T4 antibody treatment suppresses hepatic granuloma formation and abrogates antigen-induced interleukin-2 production in Schistosoma mansoni infection","volume":"54","author":"RC Mathew","year":"1986","journal-title":"Infect Immun"},{"issue":"4","key":"pntd.0008635.ref005","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1002\/eji.1830250404","article-title":"T cells expressing the gamma delta T cell receptor are not required for egg granuloma formation in schistosomiasis","volume":"25","author":"J Iacomini","year":"1995","journal-title":"Eur J Immunol"},{"issue":"9","key":"pntd.0008635.ref006","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.trstmh.2003.11.009","article-title":"Human schistosomiasis mansoni: intensity of infection differentially affects the production of interleukin-10, interferon-gamma and interleukin-13 by soluble egg antigen or adult worm antigen stimulated cultures","volume":"98","author":"AM Silveira","year":"2004","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"pntd.0008635.ref007","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3389\/fimmu.2013.00089","article-title":"The Schistosoma granuloma: friend or foe?","volume":"4","author":"E Hams","year":"2013","journal-title":"Front Immunol."},{"issue":"5","key":"pntd.0008635.ref008","doi-asserted-by":"crossref","first-page":"775","DOI":"10.4269\/ajtmh.1998.59.775","article-title":"Evolution of Schistosoma haematobium-related pathology over 24 months after treatment with praziquantel among school children in southeastern Tanzania","volume":"59","author":"CF Hatz","year":"1998","journal-title":"Am J Trop Med Hyg"},{"issue":"Suppl 5","key":"pntd.0008635.ref009","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1590\/S0074-02761992000900011","article-title":"Human schistosomiasis mansoni: studies on in vitro granuloma modulation","volume":"87","author":"JC Parra","year":"1992","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"7","key":"pntd.0008635.ref010","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nri843","article-title":"The immunobiology of schistosomiasis","volume":"2","author":"EJ Pearce","year":"2002","journal-title":"Nat Rev Immunol"},{"issue":"8","key":"pntd.0008635.ref011","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1084\/jem.20082460","article-title":"Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses","volume":"206","author":"B Everts","year":"2009","journal-title":"J Exp Med"},{"issue":"10","key":"pntd.0008635.ref012","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1084\/jem.20111381","article-title":"Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor","volume":"209","author":"B Everts","year":"2012","journal-title":"J Exp Med"},{"issue":"8","key":"pntd.0008635.ref013","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1084\/jem.20082462","article-title":"The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1).","volume":"206","author":"S Steinfelder","year":"2009","journal-title":"J Exp Med"},{"issue":"12","key":"pntd.0008635.ref014","doi-asserted-by":"crossref","first-page":"6406","DOI":"10.4049\/jimmunol.164.12.6406","article-title":"IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis","volume":"164","author":"KF Hoffmann","year":"2000","journal-title":"J Immunol"},{"issue":"10","key":"pntd.0008635.ref015","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1046\/j.1365-3024.1998.00166.x","article-title":"Human Schistosomiasis mansoni: IL-10 modulates the in vitro granuloma formation","volume":"20","author":"PL Falcao","year":"1998","journal-title":"Parasite Immunol"},{"issue":"2","key":"pntd.0008635.ref016","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1128\/IAI.74.2.1215-1221.2006","article-title":"Cytokine production associated with periportal fibrosis during chronic schistosomiasis mansoni in humans","volume":"74","author":"LF Alves Oliveira","year":"2006","journal-title":"Infect Immun"},{"issue":"2\u20133","key":"pntd.0008635.ref017","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.actatropica.2008.04.010","article-title":"Cytokines, chemokine receptors, CD4+CD25HIGH+ T-cells and clinical forms of human schistosomiasis","volume":"108","author":"A Teixeira-Carvalho","year":"2008","journal-title":"Acta Trop"},{"issue":"9","key":"pntd.0008635.ref018","first-page":"1151","article-title":"Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration","volume":"63","author":"T Crellen","year":"2016","journal-title":"Clin Infect Dis"},{"issue":"Suppl 4","key":"pntd.0008635.ref019","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1590\/S0074-02761987000800064","article-title":"Specific treatment of advanced schistosomiasis liver disease in man: favourable results","volume":"82","author":"A Coutinho","year":"1987","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"4","key":"pntd.0008635.ref020","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/00007890-197404000-00001","article-title":"Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo","volume":"17","author":"AJ Friedenstein","year":"1974","journal-title":"Transplantation"},{"issue":"5","key":"pntd.0008635.ref021","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/jor.1100090504","article-title":"Mesenchymal stem cells","volume":"9","author":"AI Caplan","year":"1991","journal-title":"J Orthop Res"},{"issue":"9","key":"pntd.0008635.ref022","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1038\/nri2395","article-title":"Mesenchymal stem cells in health and disease","volume":"8","author":"A Uccelli","year":"2008","journal-title":"Nature Reviews Immunology"},{"issue":"5411","key":"pntd.0008635.ref023","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1126\/science.284.5411.143","article-title":"Multilineage potential of adult human mesenchymal stem cells","volume":"284","author":"MF Pittenger","year":"1999","journal-title":"Science"},{"issue":"5","key":"pntd.0008635.ref024","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1002\/jcb.20904","article-title":"Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue","volume":"99","author":"R Izadpanah","year":"2006","journal-title":"J Cell Biochem"},{"issue":"2","key":"pntd.0008635.ref025","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1089\/107632701300062859","article-title":"Multilineage cells from human adipose tissue: implications for cell-based therapies","volume":"7","author":"PA Zuk","year":"2001","journal-title":"Tissue Eng"},{"issue":"5","key":"pntd.0008635.ref026","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.4049\/jimmunol.179.5.2824","article-title":"The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells","volume":"179","author":"S Jones","year":"2007","journal-title":"J Immunol"},{"issue":"10","key":"pntd.0008635.ref027","doi-asserted-by":"crossref","first-page":"3838","DOI":"10.1182\/blood.V99.10.3838","article-title":"Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli","volume":"99","author":"M Di Nicola","year":"2002","journal-title":"Blood"},{"issue":"6","key":"pntd.0008635.ref028","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/aps.2013.50","article-title":"Mesenchymal stem cells: a new trend for cell therapy","volume":"34","author":"X Wei","year":"2013","journal-title":"Acta Pharmacol Sin"},{"issue":"3","key":"pntd.0008635.ref029","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1038\/6529","article-title":"Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta","volume":"5","author":"EM Horwitz","year":"1999","journal-title":"Nat Med"},{"issue":"9624","key":"pntd.0008635.ref030","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1016\/S0140-6736(08)60690-X","article-title":"Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study","volume":"371","author":"K Le Blanc","year":"2008","journal-title":"Lancet"},{"issue":"12","key":"pntd.0008635.ref031","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1038\/bmt.2010.195","article-title":"Mesenchymal stem cell as salvage treatment for refractory chronic GVHD","volume":"45","author":"JY Weng","year":"2010","journal-title":"Bone Marrow Transplant"},{"issue":"14","key":"pntd.0008635.ref032","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1001\/archinte.162.14.1558","article-title":"Allogeneic hematopoietic stem cell transplantation: complications and results","volume":"162","author":"IA Tabbara","year":"2002","journal-title":"Arch Intern Med"},{"issue":"4","key":"pntd.0008635.ref033","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1002\/jcb.20949","article-title":"Comparison of various kinds of bone marrow stem cells for the repair of infarcted myocardium: single clonally purified non-hematopoietic mesenchymal stem cells serve as a superior source","volume":"99","author":"S Zhang","year":"2006","journal-title":"J Cell Biochem"},{"issue":"2","key":"pntd.0008635.ref034","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/0961203306075793","article-title":"Abnormality of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus","volume":"16","author":"LY Sun","year":"2007","journal-title":"Lupus"},{"issue":"8","key":"pntd.0008635.ref035","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1002\/eji.201242882","article-title":"Mesenchymal stem cells play an important role in host protective immune responses against malaria by modulating regulatory T cells","volume":"43","author":"RS Thakur","year":"2013","journal-title":"Eur J Immunol"},{"issue":"2","key":"pntd.0008635.ref036","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0002-9440(10)63134-3","article-title":"Transplanted bone marrow cells repair heart tissue and reduce myocarditis in chronic chagasic mice","volume":"164","author":"MB Soares","year":"2004","journal-title":"Am J Pathol"},{"issue":"10","key":"pntd.0008635.ref037","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003173","article-title":"New Developments of RNAi in Paracoccidioides brasiliensis: Prospects for High-Throughput, Genome-Wide, Functional Genomics.","volume":"8","author":"T Goes","year":"2014","journal-title":"Plos Neglected Tropical Diseases"},{"issue":"11","key":"pntd.0008635.ref038","doi-asserted-by":"crossref","first-page":"3843","DOI":"10.1096\/fj.09-137869","article-title":"Granulocyte colony-stimulating factor treatment in chronic Chagas disease: preservation and improvement of cardiac structure and function","volume":"23","author":"SG Macambira","year":"2009","journal-title":"Faseb j"},{"issue":"3","key":"pntd.0008635.ref039","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2217\/17460751.2.3.257","article-title":"Cellular therapy in Chagas' disease: potential applications in patients with chronic cardiomyopathy.","volume":"2","author":"MB Soares","year":"2007","journal-title":"Regen Med"},{"issue":"Suppl 1","key":"pntd.0008635.ref040","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1590\/S0074-02762009000900043","article-title":"Current status and perspectives of cell therapy in Chagas disease","volume":"104","author":"MB Soares","year":"2009","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"9","key":"pntd.0008635.ref041","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.4161\/cc.10.9.15487","article-title":"Reversion of gene expression alterations in hearts of mice with chronic chagasic cardiomyopathy after transplantation of bone marrow cells","volume":"10","author":"MB Soares","year":"2011","journal-title":"Cell Cycle"},{"issue":"1","key":"pntd.0008635.ref042","doi-asserted-by":"crossref","first-page":"96","DOI":"10.15283\/ijsc.2016.9.1.96","article-title":"Therapeutic Potential of Bone Marrow-Derived Mesenchymal Stem Cells on Experimental Liver Injury Induced by Schistosoma mansoni","volume":"9","author":"H Fikry","year":"2016","journal-title":"A Histological Study. Int J Stem Cells"},{"issue":"5","key":"pntd.0008635.ref043","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1258\/ebm.2012.011362","article-title":"Mesenchymal stem cells relieve fibrosis of Schistosoma japonicum-induced mouse liver injury","volume":"237","author":"H Xu","year":"2012","journal-title":"Exp Biol Med (Maywood)."},{"issue":"1","key":"pntd.0008635.ref044","doi-asserted-by":"crossref","first-page":"28","DOI":"10.46582\/jsrm.0801005","article-title":"Amelioration of Murine Schistosoma mansoni Induced Liver Fibrosis by Mesenchymal Stem Cells","volume":"8","author":"M Abdel Aziz","year":"2012","journal-title":"J Stem Cells Regen Med"},{"issue":"6","key":"pntd.0008635.ref045","first-page":"425","article-title":"[Inhibition of culture supernatant of mesenchymal stem cells on macrophages RAW264.7 activated by soluble egg antigen of Schistosoma japonicum].","volume":"29","author":"HJ Xu","year":"2011","journal-title":"Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi."},{"issue":"5","key":"pntd.0008635.ref046","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1645\/15-754.1","article-title":"Therapeutic Potential of Mesenchymal Stem Cells on Early and Late Experimental Hepatic Schistosomiasis Model","volume":"101","author":"SF El-Shennawy","year":"2015","journal-title":"J Parasitol"},{"issue":"1","key":"pntd.0008635.ref047","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/jcp.1138","article-title":"Surface protein characterization of human adipose tissue-derived stromal cells","volume":"189","author":"S Gronthos","year":"2001","journal-title":"J Cell Physiol"},{"issue":"8","key":"pntd.0008635.ref048","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1210\/jc.2006-2131","article-title":"Infantile hypophosphatasia: transplantation therapy trial using bone fragments and cultured osteoblasts","volume":"92","author":"RA Cahill","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"pntd.0008635.ref049","unstructured":"Catalog Record: Laboratory methods in histotechnology. 2017."},{"key":"pntd.0008635.ref050","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0065-308X(08)60475-3","article-title":"Experimental chemotherapy of Schistosomiasis mansoni.","volume":"6","author":"J Pellegrino","year":"1968","journal-title":"Adv Parasitol"},{"issue":"Pt 3","key":"pntd.0008635.ref051","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1017\/S0031182005009169","article-title":"Responses of the surface membrane and excretory system of Schistosoma mansoni to damage and to treatment with praziquantel and other biomolecules","volume":"132","author":"FA Oliveira","year":"2006","journal-title":"Parasitology"},{"issue":"4","key":"pntd.0008635.ref052","first-page":"589","article-title":"[A perfusion technic for recovery of Schistosoma mansoni from experimentally infected guinea pigs].","volume":"8","author":"J Pellegrino","year":"1956","journal-title":"Rev Bras Malariol Doencas Trop"},{"issue":"Suppl 1","key":"pntd.0008635.ref053","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1590\/S0074-02761998000700020","article-title":"Histoarchitecture of schistosomal granuloma development and involution: morphogenetic and biomechanical approaches","volume":"93","author":"HL Lenzi","year":"1998","journal-title":"Mem Inst Oswaldo Cruz"},{"issue":"1","key":"pntd.0008635.ref054","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1083\/jcb.30.1.23","article-title":"Practical stereological methods for morphometric cytology","volume":"30","author":"ER Weibel","year":"1966","journal-title":"J Cell Biol"},{"issue":"12","key":"pntd.0008635.ref055","doi-asserted-by":"crossref","first-page":"e0145261","DOI":"10.1371\/journal.pone.0145261","article-title":"Dysregulated Immune Activation in Second-Line HAART HIV+ Patients Is Similar to That of Untreated Patients.","volume":"10","author":"MS Esp\u00edndola","year":"2015","journal-title":"PLoS One."},{"issue":"4","key":"pntd.0008635.ref056","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement.","volume":"8","author":"M Dominici","year":"2006","journal-title":"Cytotherapy"},{"issue":"8","key":"pntd.0008635.ref057","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1016\/j.transproceed.2008.08.009","article-title":"Isolation and characterization of mouse mesenchymal stem cells","volume":"40","author":"JH Sung","year":"2008","journal-title":"Transplant Proc"},{"issue":"5","key":"pntd.0008635.ref058","doi-asserted-by":"crossref","first-page":"829","DOI":"10.3727\/096368915X689622","article-title":"Clinical Trials With Mesenchymal Stem Cells: An Update.","volume":"25","author":"T Squillaro","year":"2016","journal-title":"Cell Transplant"},{"issue":"6b","key":"pntd.0008635.ref059","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1111\/j.1582-4934.2009.00912.x","article-title":"Recruitment of endogenous bone marrow mesenchymal stem cells towards injured liver","volume":"14","author":"Y Chen","year":"2010","journal-title":"J Cell Mol Med"},{"issue":"7","key":"pntd.0008635.ref060","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.cellbi.2009.04.023","article-title":"Mesenchymal stem cells showed the highest potential for the regeneration of injured liver tissue compared with other subpopulations of the bone marrow","volume":"33","author":"KA Cho","year":"2009","journal-title":"Cell Biol Int"},{"issue":"4","key":"pntd.0008635.ref061","doi-asserted-by":"crossref","first-page":"e19195","DOI":"10.1371\/journal.pone.0019195","article-title":"Bone marrow-derived mesenchymal stem cells ameliorate hepatic ischemia reperfusion injury in a rat model","volume":"6","author":"H Kanazawa","year":"2011","journal-title":"PLoS One"},{"issue":"8","key":"pntd.0008635.ref062","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.1128\/AAC.00173-08","article-title":"Effect of chemotherapy with praziquantel on the production of cytokines and morbidity associated with schistosomiasis mansoni","volume":"52","author":"P Martins-Leite","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"pntd.0008635.ref063","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1590\/S0037-86821986000200003","article-title":"Rate of reversion of hepatosplenic schistosomiasis after specific therapy.","volume":"19","author":"R Dietze","year":"1986","journal-title":"Rev Soc Bras Med Trop"},{"key":"pntd.0008635.ref064","unstructured":"Coelho C, Oliveira FAd, Kusel JR, Funda\u00e7\u00e3o Oswaldo Cruz. Centro de Pesquisas Ren\u00e9 Rachou. Belo Horizonte M, Brasil., Coelho C, Kusel JR, et al. Avalia\u00e7\u00e3o do efeito do praziquantel, da oxamniquina e da associa\u00e7\u00e3o destas drogas sobre o verme adulto de Schistosoma mansoni. 2005. https:\/\/www.arca.fiocruz.br\/handle\/icict\/20772."},{"issue":"5","key":"pntd.0008635.ref065","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1080\/00034983.1989.11812373","article-title":"Effect of praziquantel on the eggs of Schistosoma mansoni, with a note on the implications for managing central nervous system schistosomiasis","volume":"83","author":"F Richards","year":"1989","journal-title":"Ann Trop Med Parasitol"},{"issue":"3","key":"pntd.0008635.ref066","first-page":"137","article-title":"Immunity: The Immune Response to Infectious and Inflammatory Disease.","volume":"80","author":"U. Alam","year":"2007","journal-title":"Yale J Biol Med"},{"issue":"4","key":"pntd.0008635.ref067","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0952-7915(95)80095-6","article-title":"Cytokine regulation of granuloma formation in schistosomiasis","volume":"7","author":"TA Wynn","year":"1995","journal-title":"Curr Opin Immunol"},{"issue":"4","key":"pntd.0008635.ref068","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1089\/scd.2009.0288","article-title":"Functional differences between mesenchymal stem cell populations are reflected by their transcriptome","volume":"19","author":"BJ Jansen","year":"2010","journal-title":"Stem Cells Dev"},{"issue":"14","key":"pntd.0008635.ref069","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1089\/scd.2011.0722","article-title":"Same or not the same? Comparison of adipose tissue-derived versus bone marrow-derived mesenchymal stem and stromal cells","volume":"21","author":"M Strioga","year":"2012","journal-title":"Stem Cells Dev"},{"issue":"6","key":"pntd.0008635.ref070","first-page":"5956","article-title":"Comparison of bone marrow-vs. adipose tissue-derived mesenchymal stem cells for attenuating liver fibrosis","volume":"14","author":"T Hao","year":"2017","journal-title":"Exp Ther Med"},{"key":"pntd.0008635.ref071","author":"V Lala","year":"2018","journal-title":"Liver Function Tests"},{"issue":"6","key":"pntd.0008635.ref072","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s00281-012-0341-9","article-title":"Induction and regulation of pathogenic Th17 cell responses in schistosomiasis","volume":"34","author":"BM Larkin","year":"2012","journal-title":"Semin Immunopathol"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0008635","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0008635","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T13:05:33Z","timestamp":1617023133000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0008635"}},"subtitle":[],"editor":[{"given":"W. Evan","family":"Secor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2020,8,27]]},"references-count":72,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020,8,27]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0008635","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,27]]}}}