{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:12:15Z","timestamp":1792735935533,"version":"4.5.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0008832","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,12,28]],"date-time":"2020-12-28T00:00:00Z","timestamp":1609113600000}}],"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T00:00:00Z","timestamp":1607904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"BMGF","doi-asserted-by":"crossref","award":["OPP1136014"],"award-info":[{"award-number":["OPP1136014"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Human African trypanosomiases caused by the\n                      <jats:italic>Trypanosoma brucei gambiense<\/jats:italic>\n                      parasite is a lethal disease targeted for eradication. One of the main disease control strategies is active case-finding through outreach campaigns. In 2014, a new method for active screening was developed with mini, motorcycle-based, teams. This study compares the cost of two active case-finding approaches, namely the traditional mobile teams and mini mobile teams, in the two health districts of the Democratic Republic of the Congo.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The financial and economic costs of both approaches were estimated from a health care provider perspective. Cost and operational data were collected for 12 months for 1 traditional team and 3 mini teams. The cost per person screened and diagnosed was calculated and univariate sensitivity analysis was conducted to identify the main cost drivers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During the study period in total 264,630 people were screened, and 23 HAT cases detected. The cost per person screened was lower for a mini team than for a traditional team in the study setting (US$1.86 versus US$2.08). A comparable result was found in a scenario analysis, assuming both teams would operate in a similar setting, with the cost per person screened by a mini team 15% lower than the cost per person screened by a traditional team (1.86 $ vs 2.14$). The main explanations for this lower cost are that mini teams work with fewer human resources, cheaper means of transportation and do not perform the Capillary Tube Centrifugation test or card agglutination test dilutions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Active HAT screening with mini mobile teams has a lower cost and could be a cost-effective alternative for active case-finding. Further research is needed to determine if mini mobile teams have similar or better yields than traditional mobile teams in terms of detections and cases successfully treated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pntd.0008832","type":"journal-article","created":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T13:49:39Z","timestamp":1607953779000},"page":"e0008832","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Cost of a new method of active screening for human African trypanosomiasis in the Democratic Republic of the Congo"],"prefix":"10.1371","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2432-9818","authenticated-orcid":true,"given":"Rian","family":"Snijders","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Fukinsia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Claeys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Mpanya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Epco","family":"Hasker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filip","family":"Meheus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7624-7905","authenticated-orcid":true,"given":"Erick","family":"Miaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marleen","family":"Boelaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2020,12,14]]},"reference":[{"issue":"12","key":"pntd.0008832.ref001","doi-asserted-by":"crossref","first-page":"e303","DOI":"10.1371\/journal.pntd.0000303","article-title":"The natural progression of gambiense sleeping sickness: What is the evidence?","volume":"2","author":"F Checchi","year":"2008","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"2","key":"pntd.0008832.ref002","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1371\/journal.pmed.0050055","article-title":"Eliminating human African trypanosomiasis: where do we stand and what comes next?","volume":"5","author":"PP Simarro","year":"2008","journal-title":"PLoS Medicine"},{"key":"pntd.0008832.ref003","first-page":"257","article-title":"Epidemiology of human African trypanosomiasis","volume":"6","author":"JR Franco","year":"2014","journal-title":"Clinical Epidemiology"},{"key":"pntd.0008832.ref004","volume-title":"Global Health Observatory data repository: Number of new reported cases (T.b. gambiense)","author":"World Health Organization (WHO)","year":"2020"},{"issue":"6","key":"pntd.0008832.ref005","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/tmi.12483","article-title":"Contemporary and emerging strategies for eliminating human African trypanosomiasis due to Trypanosoma brucei gambiense: review","volume":"20","author":"P Steinmann","year":"2015","journal-title":"Tropical Medicine & International Health"},{"issue":"2","key":"pntd.0008832.ref006","doi-asserted-by":"crossref","first-page":"e0003397","DOI":"10.1371\/journal.pntd.0003397","article-title":"A literature review of economic evaluations for a neglected tropical disease: human African trypanosomiasis (\"sleeping sickness\")","volume":"9","author":"CS Sutherland","year":"2015","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"1","key":"pntd.0008832.ref007","doi-asserted-by":"crossref","first-page":"e1467","DOI":"10.1371\/journal.pntd.0001467","article-title":"Should I get screened for sleeping sickness? 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