{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:28:44Z","timestamp":1791937724859,"version":"4.3.4"},"update-to":[{"DOI":"10.1371\/journal.pntd.0008918","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2020,12,21]],"date-time":"2020-12-21T00:00:00Z","timestamp":1608508800000}}],"reference-count":63,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T00:00:00Z","timestamp":1607472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"WHO\/TDR\/EMRO","award":["SGS 14\/34"],"award-info":[{"award-number":["SGS 14\/34"]}]},{"name":"European and Developing Countries Clinical Trials Partnership\/PANDORA"},{"name":"European and Developing Countries Clinical Trials Partnership\/PANDORA"},{"name":"European and Developing Countries Clinical Trials Partnership\/PANDORA"},{"name":"European and Developing Countries Clinical Trials Partnership\/PANDORA"},{"name":"European and Developing Countries Clinical Trials Partnership\/PANDORA"},{"name":"European and Developing Countries Clinical Trials Partnership\/PANDORA"},{"name":"European and Developing Countries Clinical Trials Partnership\/PANDORA"},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Egyptian Fulbright Mission program"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Dengue is a rapidly growing public health threat in Kassala state, eastern Sudan. The objective of this study was to determine the seroprevalence, entomological transmission indices, and socioeconomic risk factors associated with dengue in this region. A cross-sectional community-based study was conducted in four dengue-endemic sites; Khatmia, West Gash, Thoriba, and Shokriya between March 2016 to March 2017. Enzyme-linked immunosorbent assay (ELISA) of immunoglobulin G (IgG) was used to determine the prevalence of dengue virus among the study participants. An entomological survey was conducted using pyrethrum spray catch and dipping for the collection of adults and aquatic stages of <jats:italic>Aedes aegypti<\/jats:italic>, respectively. Ribonucleic acid was extracted from the buffy coat of participants as well as from adult female <jats:italic>Ae<\/jats:italic>. <jats:italic>aegypti<\/jats:italic> to assess the possible circulation of dengue virus using Reverse Transcription Polymerase Chain Reaction (RT-PCR). Multiple logistic regression model was used to estimate the association between potential risk factors and dengue seropositivity. A total of 409 persons were recruited to the study: 45.5% were in the 20\u201339 years\u2019 age category; 57.9% were living in houses with 6\u201310 persons; and 29.1% had at most secondary school education. In the majority (65.8%) of the households, the socioeconomic status was low (P&lt;0.001). Long-lasting insecticide-treated bed nets were used in 56.5% of the households. Over three-quarters (77.8%) claimed not to have experienced febrile illness in the last three months. Routine entomological survey across Kassala state identified a total of 3,304 larvae and 390 pupae <jats:italic>Ae<\/jats:italic>. <jats:italic>aegypti<\/jats:italic>, respectively. The overall house index was 32.8% and Breteau Index was 35.96% (146\/406). The overall pupal demographic index was 13.31%, and the pupal children index was 97.26%. Antibodies against IgG were detected from 66 (42.04%) out of a total of 157 sera. Twenty-two positive sera (75.9%) were collected from Khatmia. A total of 329 adults <jats:italic>Ae<\/jats:italic>. <jats:italic>aegypti<\/jats:italic> were identified but only one (0.3%) was positive for DENV in Khatmia. Finally, four independent risk factors were identified to derive dengue circulation in Kassala: elder age (&gt; 60 years) (OR 6.31, CI 1.09\u201336.36); type of bathroom (OR 3.52, CI 1.35\u20139.20); using water-based air conditioner (OR 6.90, CI 1.78\u201326.85) and previous infection of any household member with dengue (OR 28.73, CI 3.31\u2013249.63). Our findings suggest that Kassala state is facing an increasing occurrence of dengue and emphasizes the need for developing appropriate interventions to address the identified risk factors, and place control programs into actions. Establishment of routine dengue epidemiological and entomological surveillance, and climate warning systems will contribute to early warning and timely detection and response to emerging outbreaks.<\/jats:p>","DOI":"10.1371\/journal.pntd.0008918","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T00:31:09Z","timestamp":1607560269000},"page":"e0008918","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":27,"title":["Seroprevalence and associated risk factors of Dengue fever in Kassala state, eastern 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first outbreak of dengue fever in Greater Darfur, Western Sudan.","volume":"4","author":"A Ahmed","year":"2019","journal-title":"Trop Med Infect Dis"},{"key":"pntd.0008918.ref018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1478-7954-9-1","article-title":"Measuring the burden of arboviral diseases: the spectrum of morbidity and mortality from four prevalent infections.","volume":"9","author":"A LaBeaud","year":"2011","journal-title":"Popul Health Metrol"},{"key":"pntd.0008918.ref019","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1128\/CMR.11.3.480","article-title":"Dengue and dengue hemorrhagic fever","volume":"11","author":"D Gubler","year":"1998","journal-title":"Clin Microbiol Rev"},{"issue":"280","key":"pntd.0008918.ref020","first-page":"1","article-title":"Epidemiological risk factors associated with high global frequency of inapparent dengue virus infections.","volume":"5","author":"L Grange","year":"2014","journal-title":"Frontiers 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J Trop Med"},{"issue":"1","key":"pntd.0008918.ref026","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3390\/v12010081","article-title":"Risks and challenges of arboviral diseases in Sudan: The urgent need for actions.","volume":"12","author":"A Ahmed","year":"2020","journal-title":"Viruses"},{"key":"pntd.0008918.ref027","doi-asserted-by":"crossref","first-page":"58","DOI":"10.7883\/yoken.JJID.2018.267","article-title":"Molecular investigation of dengue virus serotype 2 circulation in Kassala state, Sudan.","volume":"72","author":"Z Hamid","year":"2018","journal-title":"Japanese J Infect Dis"},{"key":"pntd.0008918.ref028","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1002\/jmv.23218","article-title":"Epidemiology of dengue infections in Kassala, Eastern Sudan.","volume":"84","author":"T Abdallah","year":"2012","journal-title":"J Med Virolo"},{"key":"pntd.0008918.ref029","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1186\/s12889-020-08656-y","article-title":"Recent transmission of dengue virus and associated risk factors among residents of Kassala state, eastern Sudan.","volume":"20","author":"M Eldigail","year":"2020","journal-title":"BMC Public Health."},{"key":"pntd.0008918.ref030","unstructured":"Shareef H. Sero-epidemiology of dengue fever in Kassala locality. PhD thesis, Community Medicine Council, Sudan Medical Specialization Board, Sudan. 2011."},{"key":"pntd.0008918.ref031","first-page":"487","article-title":"Seroprevalence of dengue infections in the Kassala state in the eastern part of the Sudan in 2011.","volume":"8","author":"S Himatt","year":"2015","journal-title":"J InfectPublic Health"},{"issue":"3","key":"pntd.0008918.ref032","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jcv.2007.04.003","article-title":"Evaluation of immunoglobulin M and G capture enzyme-linked immunosorbent assay Panbio kits for diagnostic dengue infections.","volume":"39","author":"S Arya","year":"2007","journal-title":"J Clin Virol"},{"key":"pntd.0008918.ref033","unstructured":"World Health Organization (WHO). Lymphatic filariasis: a handbook of practical entomology for national lymphatic filariasis elimination programmes. 2013. Geneva 27, Switzerland WHO\/HTM\/NTD\/PCT\/2013.10."},{"issue":"1","key":"pntd.0008918.ref034","first-page":"1","article-title":"Pictorial key for the identification of the subfamilies of Culicidae, genera of Culicinae, and subgenera of Aedes mosquitoes of the Afrotropical region (Diptera: Culicidae).","volume":"103","author":"Y Huang","year":"2011","journal-title":"Proc. Entomol. Soc. 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Med. Infect. Dis."},{"key":"pntd.0008918.ref045","unstructured":"World Health Organization (WHO). Better environmental management for control of dengue. 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