{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T19:04:58Z","timestamp":1784315098455,"version":"3.55.0"},"reference-count":13,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T00:00:00Z","timestamp":1616630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Mycetoma is a neglected tropical disease which is endemic in Senegal. Although this subcutaneous mycosis is most commonly found on the foot, extrapodal localisations have also been found, including on the leg, knee, thigh, hand, and arm. To our knowledge, no case of blood-spread eumycetoma has been reported in Senegal. Here, we report a case of pulmonary mycetoma secondary to a <jats:italic>Madurella mycetomatis<\/jats:italic> knee eumycetoma. The patient was a 41-year-old farmer living in Louga, Senegal, where the Sudano-Sahelian climate is characterised by a short and unstable rainy season and a steppe vegetation. He suffered a trauma to the right more than 20 years previously and had received treatment for more than 10 years with traditional medicine. He consulted at Le Dantec University Hospital in Dakar for treatment of a right knee mycetoma which had been diagnosed more than 10 years ago. He had experienced a chronic cough for more than a year; tuberculosis documentation was negative. Grains collected from the knee and the sputum isolated <jats:italic>M<\/jats:italic>. <jats:italic>mycetomatis<\/jats:italic>, confirmed by the rRNA gene ITS regions nucleotide sequence analysis. An amputation above the knee was performed, and antibacterial and antifungal therapy was started with amoxicillin-clavulanic acid and terbinafine. The patient died within a month of his discharge from hospital.<\/jats:p>","DOI":"10.1371\/journal.pntd.0009238","type":"journal-article","created":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T15:14:42Z","timestamp":1616685282000},"page":"e0009238","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pulmonary Madurella mycetomatis mycetoma secondary to knee eumycetoma, Senegal"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7033-1169","authenticated-orcid":true,"given":"Khadim","family":"Diongue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6478-7875","authenticated-orcid":true,"given":"Mamadou Alpha","family":"Diallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamine","family":"Sarr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8326-5359","authenticated-orcid":true,"given":"Mame Cheikh","family":"Seck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludivine","family":"Br\u00e9chard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouhamadou","family":"Ndiaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1118-4998","authenticated-orcid":true,"given":"Aida Sadikh","family":"Badiane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3293-5276","authenticated-orcid":true,"given":"St\u00e9phane","family":"Ranque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daouda","family":"Ndiaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,3,25]]},"reference":[{"issue":"5","key":"pntd.0009238.ref001","first-page":"376","article-title":"Prise en charge des myc\u00e9tomes en Afrique de l\u2019Ouest","volume":"96","author":"M Develoux","year":"2003","journal-title":"Bull Soc Pathol Exot"},{"issue":"7","key":"pntd.0009238.ref002","doi-asserted-by":"crossref","first-page":"e0004735","DOI":"10.1371\/journal.pntd.0004735","article-title":"Multiple Mycetoma Lung Secondaries from Knee Eumycetoma: An Unusual Complication","volume":"10","author":"ESW Mohamed","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"10","key":"pntd.0009238.ref003","doi-asserted-by":"crossref","first-page":"e0004945","DOI":"10.1371\/journal.pntd.0004945","article-title":"Mycetoma Pulmonary Secondaries from a Gluteal Eumycetoma: An Unusual Presentation","volume":"10","author":"NA Mohamed","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"issue":"5","key":"pntd.0009238.ref004","first-page":"e0006391","article-title":"A holistic approach to the mycetoma management. 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A rare localization, a particular form","volume":"84","author":"MH Sy","year":"1998","journal-title":"Rev Chir Orthop Reparatrice Appar Mot"},{"issue":"5","key":"pntd.0009238.ref009","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.jfo.2012.11.004","article-title":"Myc\u00e9tome orbitaire: \u00e0 propos d\u2019un cas.","volume":"36","author":"NN Gueye","year":"2013","journal-title":"J Fr Ophtalmol"},{"key":"pntd.0009238.ref010","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.mycmed.2019.03.001","article-title":"Dermatophytic mycetoma of the scalp due to an atypical strain of Microsporum audouinii identified by MALDI-TOF MS and ITS sequencing","volume":"29","author":"K Diongue","year":"2019","journal-title":"Journal de Mycologie M\u00e9dicale"},{"key":"pntd.0009238.ref011","first-page":"140","article-title":"Aspects actuels des myc\u00e9tomes au S\u00e9n\u00e9gal; A propos de 109 cas","volume":"10","author":"B Ndiaye","year":"2000","journal-title":"J Mycol Med"},{"key":"pntd.0009238.ref012","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S1773-035X(11)70826-7","article-title":"Le diagnostic biologique des myc\u00e9tomes","volume":"430","author":"M Develoux","year":"2011","journal-title":"Revue francophone des laboratoires"},{"issue":"6","key":"pntd.0009238.ref013","doi-asserted-by":"crossref","first-page":"e0004690","DOI":"10.1371\/journal.pntd.0004690","article-title":"The Surgical Treatment of Mycetoma","volume":"10","author":"SH Suleiman","year":"2016","journal-title":"PLoS Negl Trop Dis"}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0009238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,25]],"date-time":"2021-03-25T15:14:49Z","timestamp":1616685289000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0009238"}},"subtitle":[],"editor":[{"given":"Claudio Guedes","family":"Salgado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,3,25]]},"references-count":13,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0009238","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,25]]}}}