{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T17:49:08Z","timestamp":1757699348697,"version":"3.40.5"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Uniting to Combat Neglected Tropical Diseases"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>The World Health Organization\u2019s (WHO) Neglected Tropical Disease (NTD) Road Map for 2021\u20132030 was recently endorsed by all member states at the World Health Assembly in November 2020. Although only 3 of the 20 NTDs are endemic in Canada (i.e., echinococcosis, rabies, and scabies), the Canadian research community has contributed to advancing the knowledge base of all 20 NTDs. Previous research comprehensively detailed Canadian research on 11 NTDs between 1950 and 2010 using a network analysis approach. The specific objective of the present analysis was to update the publication record over the last decade (2010\u20132019) to include all 20 NTDs.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Materials and methods<\/jats:title>\n<jats:p>A bibliometric analysis was conducted in Scopus and Web of Science databases (for English or French articles published between January 1, 2010 and December 31, 2019) using appropriate search terms for each of the 20 NTDs and where at least 1 of the authors had a Canadian institution address. A 21st search was added to include publications including multiple NTDs or a discussion of NTDs in general. Following assessment of inclusion and exclusion criteria, 2 reviewers independently screened all abstracts, with discordant observations rereviewed to arrive at an agreement. Duplicates were removed.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 1,790 publications were retrieved (1,738 with a disease\u2013specific NTD focus and 52 with a general NTD focus, resulting in 1,659 unique publications), giving an average of over 160 articles per year. Over 80% were classified as full\u2013length research articles. The top 3 journals in terms of frequency were <jats:italic>PLOS Neglected Tropical Diseases<\/jats:italic>, <jats:italic>PLOS ONE<\/jats:italic>, and the <jats:italic>American Journal of Tropical Medicine and Hygiene<\/jats:italic>. Authors\u2019 institutions were from all Canadian provinces. While all 20 NTDs were addressed in these publications, the 5 most commonly studied were leishmaniasis, dengue fever and chikungunya, Chagas disease, soil\u2013transmitted helminthiases, and rabies.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Canadian researchers across the country have contributed to the evidence base of all 20 NTDs, publishing an average of over 160 publications per year between 2010 and 2019. As WHO NTD Road Map 2021\u20132030 rolls out globally, the Canadian research community, in collaboration with its partners and in solidarity with people living in vulnerable circumstances in endemic regions worldwide, is well positioned to meet future research challenges so that the goal of eliminating the disease burden attributable to NTDs can be achieved.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pntd.0009476","type":"journal-article","created":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T17:27:21Z","timestamp":1625160441000},"page":"e0009476","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Canadian contributions to research on neglected tropical diseases"],"prefix":"10.1371","volume":"15","author":[{"given":"Theresa W.","family":"Gyorkos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2822-4730","authenticated-orcid":true,"given":"H\u00e9l\u00e8ne","family":"Carabin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maneesh","family":"Phillip","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3210-749X","authenticated-orcid":true,"given":"Leshawn","family":"Benedict","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2449-7093","authenticated-orcid":true,"given":"Amy","family":"Davis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1605-3911","authenticated-orcid":true,"given":"Janet","family":"Hatcher Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kishor M.","family":"Wasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9012-4212","authenticated-orcid":true,"given":"Momar","family":"Ndao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7213-1577","authenticated-orcid":true,"given":"Alison","family":"Krentel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,7,1]]},"reference":[{"issue":"4","key":"pntd.0009476.ref001","first-page":"354","article-title":"Echinococcus alveolaris","volume":"36","author":"E James","year":"1937","journal-title":"Can Med Assoc J"},{"key":"pntd.0009476.ref002","first-page":"600","article-title":"The epidemiology of echinococcosis in Canada","volume":"96","author":"GA Webster","year":"1967","journal-title":"Can Med Assoc J"},{"issue":"73","key":"pntd.0009476.ref003","article-title":"Echinococcus multilocularis in North America: the great unknown","volume":"21","author":"A Massolo","year":"2014","journal-title":"Parasite"},{"issue":"4","key":"pntd.0009476.ref004","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1056\/NEJMc1814975","article-title":"European Echinococcus multilocularis identified in patients in Canada","volume":"381","author":"A Massolo","year":"2019","journal-title":"N Engl J Med"},{"key":"pntd.0009476.ref005","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/bs.apar.2016.11.001","article-title":"Global distribution of alveolar and cystic echinococcosis","volume":"95","author":"P Deplazes","year":"2017","journal-title":"Adv Parasitol"},{"volume-title":"Parasites of the Colder Climates","year":"2003","author":"TW Gyorkos","key":"pntd.0009476.ref006"},{"key":"pntd.0009476.ref007","unstructured":"Public Health Agency of Canada. 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