{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:37:24Z","timestamp":1790195844648,"version":"4.1.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0009590","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000}}],"reference-count":28,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T00:00:00Z","timestamp":1628553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"bill & melinda gates foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"crossref"}]},{"name":"lymphatic filariasis support center at emory university"},{"name":"task force for global health, liverpool school of tropical medicine lymphatic filariasis support centre"},{"DOI":"10.13039\/100005527","name":"the carter center","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100005527","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Lymphatic filariasis (LF) is a mosquito-transmitted parasitic disease that is a leading cause of disability globally. The island of Hispaniola, which the Dominican Republic shares with Haiti, accounts for approximately 90% of LF cases in the Americas region. In 1998, the Dominican Ministry of Public Health created the Program to Eliminate Lymphatic Filariasis (PELF) with the goal of eliminating LF transmission by 2020. Baseline mapping revealed 19 (12% of total) endemic municipalities clustered into three geographic foci (Southwest, La Ci\u00e9naga and East), with a total at-risk population of 262,395 people. Beginning in 2002, PELF sequentially implemented mass drug administration (MDA) in these foci using albendazole and diethylcarbamazine (DEC). In total, 1,174,050 treatments were given over three to five annual rounds of house-to-house MDA per focus with a median coverage of 81.7% (range 67.4%\u201392.2%). By 2018, LF antigen prevalence was less than 2% in all foci, thus meeting criteria to stop MDA and begin post-treatment surveillance (PTS). This success has been achieved against a shifting landscape of limited domestic funding, competing domestic public health priorities, and sporadic external donor support. Remaining steps include the need to scale-up morbidity management and disability prevention services for LF and to continue PTS until LF transmission is interrupted across Hispaniola.<\/jats:p>","DOI":"10.1371\/journal.pntd.0009590","type":"journal-article","created":{"date-parts":[[2021,8,10]],"date-time":"2021-08-10T17:36:37Z","timestamp":1628616997000},"page":"e0009590","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Lymphatic filariasis elimination in the Dominican Republic: History, progress, and remaining steps"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9718-2610","authenticated-orcid":true,"given":"Manuel","family":"Gonzales","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1332-4832","authenticated-orcid":true,"given":"Gregory S.","family":"Noland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1218-3305","authenticated-orcid":true,"given":"Eileen F.","family":"Mariano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4237-9229","authenticated-orcid":true,"given":"Stephen","family":"Blount","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,8,10]]},"reference":[{"issue":"43","key":"pntd.0009590.ref001","first-page":"509","article-title":"Global programme to eliminate lymphatic filariasis: progress report, 2019","volume":"95","author":"World Health Organization","year":"2020","journal-title":"Wkly Epidemiol Rec"},{"issue":"3","key":"pntd.0009590.ref002","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1089\/lrb.2013.0021","article-title":"Insights into the pathogenesis of disease in human lymphatic filariasis","volume":"11","author":"TB Nutman","year":"2013","journal-title":"Lymphat Res Biol"},{"issue":"3","key":"pntd.0009590.ref003","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.pec.2007.06.015","article-title":"Disrupted social connectedness among Dominican women with chronic filarial lymphedema","volume":"68","author":"B Person","year":"2007","journal-title":"Patient Educ Couns"},{"issue":"6","key":"pntd.0009590.ref004","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1111\/j.1365-3156.2005.01426.x","article-title":"Physical and psychosocial burden due to lymphatic filariasis as perceived by patients and medical experts","volume":"10","author":"A Krishna Kumari","year":"2005","journal-title":"Trop Med Int Health"},{"issue":"41","key":"pntd.0009590.ref005","first-page":"457","article-title":"Global programme to eliminate lymphatic filariasis: progress report, 2018","volume":"94","author":"World Health Organization","year":"2019","journal-title":"Wkly Epidemiol Rec"},{"issue":"RR-16","key":"pntd.0009590.ref006","first-page":"1","article-title":"Recommendations of the International Task Force for Disease Eradication","volume":"42","author":"Centers for Disease Control and Prevention","year":"1993","journal-title":"Morbidity and Mortality Weekly Report"},{"key":"pntd.0009590.ref007","unstructured":"World Health Assembly. 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