{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:55:22Z","timestamp":1792454122593,"version":"4.5.0"},"reference-count":52,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T00:00:00Z","timestamp":1632182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Intestinal schistosomiasis is a neglected tropical disease, causing morbidity and mortality in tropical and subtropical countries. Despite the frequent implementation of mass drug administration with praziquantel, the reinfection with <jats:italic>Schistosoma mansoni<\/jats:italic> is still common in Yemen. In addition, there is a scarcity of information on the impact of <jats:italic>S<\/jats:italic>. <jats:italic>mansoni<\/jats:italic> on nutritional status and anemia among schoolchildren. The present study aimed to determine prevalence and risk factors of intestinal schistosomiasis and investigate its impact on nutritional status and anemia among schoolchildren in Sana\u2019a Governorate, Yemen. It was conducted in 2018 on 445 schoolchildren aged 5\u201315 years. Biodata, socio-economic, demographic, behavioral and environmental data were collected using a standard questionnaire. <jats:italic>S<\/jats:italic>. <jats:italic>mansoni<\/jats:italic> was identified and quantified by microscopic examination of Kato-Katz fecal smear. Hemoglobin concentration and anthropometric measurements were estimated using standard methods. The prevalence of <jats:italic>S<\/jats:italic>. <jats:italic>mansoni<\/jats:italic> was higher in Al-Haimah Al-Dakheliah (33.9%) than Bani Mater (1.4%). Household without tap water (Adjusted Odds Ratio (AOR) = 2.9, 95% Confidence interval (CI): 1.12, 7.55, <jats:italic>P<\/jats:italic> = 0.028) was the independent risk factor of the infection. The prevalence of wasting and stunting was 25.0% (95%CI: 21.2%, 29.2%) and 45.8% (95%CI: 41.2%, 50.5%), respectively. The prevalence of underweight among schoolchildren aged 5\u201310 years was 27.3% (95%CI: 21.9%, 33.4%). The prevalence of anemia was 31.7% (95%CI: 27.5%, 36.2%) with 0.5%, 21.1% and 10.1% being severe, moderate and mild anemia, respectively. <jats:italic>S<\/jats:italic>. <jats:italic>mansoni<\/jats:italic> (AOR = 4.1, 95%CI: 2.16, 7.84, <jats:italic>P<\/jats:italic> &lt; 0.001) and early adolescence (AOR = 6.8, 95%CI: 4.26, 10.82, <jats:italic>P<\/jats:italic> &lt; 0.001) were independent predictors of stunting among schoolchildren. The early adolescent schoolchildren (AOR = 3.1, 95%CI: 1.86, 4.97, <jats:italic>P<\/jats:italic> &lt; 0.001) and children from families with low (AOR = 2.1, 95%CI: 1.01, 4.15, <jats:italic>P<\/jats:italic> = 0.046) or moderate wealth (AOR = 2.3, 95%CI: 1.11, 4.77, <jats:italic>P<\/jats:italic> = 0.026) were significantly more wasted.<\/jats:p>\n<jats:p>Early adolescence (AOR = 1.8, 95%CI:1.14, 2.78, <jats:italic>P<\/jats:italic> = 0.011), female (AOR = 1.6, 95%CI: 1.03, 2.43, <jats:italic>P<\/jats:italic> = 0.038) and Al-Haimah Al-Dakheliah District (AOR = 3.4, 95%CI: 1.20, 9.55, <jats:italic>P<\/jats:italic> = 0.021) were independent risk factors for anemia. The study findings indicate highly focal prevalence of schistosomiasis in Sana\u2019a Governorate with a public health significance that varies from low to high risk. Approximately half of schoolchildren were stunted, which was associated with <jats:italic>S<\/jats:italic>. <jats:italic>mansoni<\/jats:italic> infection and early adolescence. One quarter of schoolchildren were wasted with early adolescent schoolchildren and children from poor families being at high risk of wasting. Anemia was a moderate public health threat affecting the female and the early adolescent schoolchildren. The study suggests the implementation of control measures to combat schistosomiasis and integrated diseases control programmes to improve the health status of schoolchildren in Sana\u2019a Governorate.<\/jats:p>","DOI":"10.1371\/journal.pntd.0009757","type":"journal-article","created":{"date-parts":[[2021,9,21]],"date-time":"2021-09-21T17:36:10Z","timestamp":1632245770000},"page":"e0009757","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Intestinal schistosomiasis among schoolchildren in Sana\u2019a Governorate, Yemen: Prevalence, associated factors and its effect on nutritional status and anemia"],"prefix":"10.1371","volume":"15","author":[{"given":"Sami Ahmed","family":"Al-Haidari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8340-5219","authenticated-orcid":true,"given":"Mohammed A. 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