{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:25:05Z","timestamp":1790810705168,"version":"4.1.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0009807","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T00:00:00Z","timestamp":1633564800000}}],"reference-count":14,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T00:00:00Z","timestamp":1632700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Helen Keller International , Health and Development International, Deloitte, World Vision, Americares, and the AIM Initiative","award":["7200AA18CA00011"],"award-info":[{"award-number":["7200AA18CA00011"]}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"\nBackground<\/jats:title>\nGuinea reported its first case of COVID-19 on March 12, 2020. Soon thereafter, a national state of emergency was declared, all land borders were closed, schools were shut down, and public gatherings were limited. Many health activities, including field-based activities targeting neglected tropical diseases (NTDs), were paused. The World Health Organization (WHO) issued updated guidance on the resumption of NTD field-based activities on July 27, 2020. In response, the Guinea Ministry of Health (MoH) and its partners planned and resumed mass drug administration (MDA) in mid-August to September 2020 in 19 health districts.<\/jats:p>\n<\/jats:sec>\n\nMethodology\/principal findings<\/jats:title>\nA risk-benefit assessment was conducted to identify potential risks associated with the MDA in the COVID-19 context. Following this assessment, a risk mitigation plan with barrier measures was developed to guide MDA implementation. These measures included COVID-19 testing for all national staff leaving Conakry, mask wearing, social distancing of two meters, and hand washing\/sanitizing. A checklist was developed and used to monitor compliance to risk mitigation measures. Data on adherence to risk mitigation measures were collected electronically during the MDA. A total of 120 checklists, representing 120 community drug distributor (CDD) teams (two CDDs per team) and 120 households, were completed. Results indicated that washing or disinfecting hands was practiced by 68.3% of CDD teams, compared to 45.0% among households. Face masks to cover the mouth and nose were worn by 79.2% of CDD teams, while this was low among households (23.3%). In 87.5% of households, participants did not touch the dose pole and in 88.3% of CDD teams, CDDs did not touch the hands of the participants while giving the drugs. A large majority of CDD teams (94.2%) and household members (94.2%) were willing to participate in the MDA despite the pandemic. The epidemiological coverage was \u226565% for lymphatic filariasis, onchocerciasis and soil-transmitted helminths in 10 out of 19 HDs and \u226575% for schistosomiasis for school-aged children in 7 out of 11 HDs.<\/jats:p>\n<\/jats:sec>\n\nConclusions\/significance<\/jats:title>\nGuinea was one of the first countries in Africa to resume MDA activities during the COVID-19 pandemic without causing an observed increase of transmission. The development of a risk mitigation plan and a method to monitor adherence to barrier measures was critical to this unprecedented effort. The rapid incorporation of COVID-19 barrier measures and their acceptance by CDDs and household members demonstrated both the adaptability of the National NTD Program to respond to emerging issues and the commitment of the MoH to implement NTD programs.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pntd.0009807","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T19:52:31Z","timestamp":1632772351000},"page":"e0009807","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["Implementation of mass drug administration for neglected tropical diseases in Guinea during the COVID-19 pandemic"],"prefix":"10.1371","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3819-9361","authenticated-orcid":true,"given":"Fatoumata","family":"Sakho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9768-3239","authenticated-orcid":true,"given":"Christelly Flore","family":"Badila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6712-310X","authenticated-orcid":true,"given":"Benoit","family":"Dembele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aissatou","family":"Diaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5222-8061","authenticated-orcid":true,"given":"Abdoul Karim","family":"Camara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamine","family":"Lamah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8585-4894","authenticated-orcid":true,"given":"Steven D.","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5928-1570","authenticated-orcid":true,"given":"Angel","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5865-2528","authenticated-orcid":true,"given":"Brian B.","family":"Fuller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1713-4809","authenticated-orcid":true,"given":"Katherine A.","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Achille","family":"Kabore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaobi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Weaver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,9,27]]},"reference":[{"key":"pntd.0009807.ref001","unstructured":"World Health Organization. Neglected Tropical Diseases [Internet]. [cited 2021 Mar 31]. Available from: https:\/\/www.who.int\/teams\/maternal-newborn-child-adolescent-health-and-ageing\/maternal-health\/about\/control-of-neglected-tropical-diseases"},{"issue":"7","key":"pntd.0009807.ref002","doi-asserted-by":"crossref","first-page":"e2865","DOI":"10.1371\/journal.pntd.0002865","article-title":"The Global Burden of Disease Study 2010: Interpretation and Implications for the Neglected Tropical Diseases","volume":"8","author":"PJ Hotez","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"pntd.0009807.ref003","volume-title":"Accelerating work to overcome the global impact of neglected tropical diseases: a roadmap for implementation","author":"World Health Organization","year":"2012"},{"key":"pntd.0009807.ref004","volume-title":"Sustaining the drive to overcome the global impact of neglected tropical diseases: second WHO report on neglected diseases","author":"World Health Organization","year":"2013"},{"issue":"8","key":"pntd.0009807.ref005","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1093\/cid\/ciaa933","article-title":"Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation","volume":"72","author":"J Toor","year":"2021","journal-title":"Clin Infect Dis"},{"issue":"6","key":"pntd.0009807.ref006","doi-asserted-by":"crossref","first-page":"e0006585","DOI":"10.1371\/journal.pntd.0006585","article-title":"Baseline trachoma prevalence in Guinea: Results of national trachoma mapping in 31 health districts","volume":"12","author":"A G\u00e9opogui","year":"2018","journal-title":"PLoS Negl Trop Dis"},{"key":"pntd.0009807.ref007","volume-title":"Plan Directeur De Lutte Contre Les Maladies Tropicales N\u00e9glig\u00e9es En Guin\u00e9e (2017\u20132020)","author":"Minist\u00e8re de la Sant\u00e9","year":"2017"},{"key":"pntd.0009807.ref008","volume-title":"Regional Strategy on Neglected Tropical Diseases in the WHO African Region 2014\u20132020","author":"Regional Committee for Africa 63.","year":"2013"},{"issue":"5_Suppl","key":"pntd.0009807.ref009","first-page":"211","article-title":"Stopping mass drug administration for trachoma in 15 health districts in Guinea","volume":"103","author":"S Fatoumata","year":"2020","journal-title":"Am J Trop Med Hyg"},{"key":"pntd.0009807.ref010","unstructured":"Le Bureau de Presse de la Pr\u00e9sidence. Declaration Du President De La Republique Sur De Nouvelles Mesures Contre Le Covid-19 En Guinee [Internet]. [cited 2021 Mar 31]. Available from: https:\/\/gouvernement.gov.gn\/index.php\/communique\/5064-declaration-du-president-de-la-republique-sur-de-nouvelles-mesures-contre-le-covid-19-en-guinee"},{"key":"pntd.0009807.ref011","volume-title":"Considerations for implementing mass treatment, active case-finding and population-based surveys for neglected tropical diseases in the context of the COVID-19 pandemic: interim guidance","author":"World Health Organization","year":"2020"},{"key":"pntd.0009807.ref012","volume-title":"Le troisi\u00e8me Recensement G\u00e9n\u00e9ral de la Population et de l\u2019Habitation (RGPH-3)","author":"National Institute of Statistics (Guinea)","year":"2017"},{"key":"pntd.0009807.ref013","volume-title":"Monitoring and epidemiological assessment of mass drug administration in the global programme to eliminate lymphatic filariasis: a manual for national elimination programmes","author":"World Health Organization","year":"2011"},{"key":"pntd.0009807.ref014","unstructured":"United Nations Office for the Coordination of Humanitarian Affairs, Afrique de l\u2019Ouest et du Centre COVID-19 \u2013Situation de l\u2019\u00e9pid\u00e9mie (cas et d\u00e9c\u00e8s). 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