{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T23:40:57Z","timestamp":1773099657677,"version":"3.50.1"},"update-to":[{"DOI":"10.1371\/journal.pntd.0010534","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T00:00:00Z","timestamp":1658361600000}}],"reference-count":79,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T00:00:00Z","timestamp":1657497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008793","name":"Universidad del Rosario","doi-asserted-by":"crossref","award":["Internal funds"],"award-info":[{"award-number":["Internal funds"]}],"id":[{"id":"10.13039\/501100008793","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Chagas disease is considered a public health issue in Colombia, where many regions are endemic. <jats:italic>Triatoma dimidiata<\/jats:italic> is an important vector after <jats:italic>Rhodnius prolixus<\/jats:italic>, and it is gaining importance in Boyac\u00e1, eastern Colombia. Following the recent elimination of <jats:italic>R<\/jats:italic>. <jats:italic>prolixus<\/jats:italic> in the region, it is pivotal to understand the behavior of <jats:italic>T<\/jats:italic>. <jats:italic>dimidiata<\/jats:italic> and the transmission dynamics of <jats:italic>T<\/jats:italic>. <jats:italic>cruzi<\/jats:italic>. We used qPCR and Next Generation Sequencing (NGS) to evaluate <jats:italic>T<\/jats:italic>. <jats:italic>cruzi<\/jats:italic> infection, parasite load, feeding profiles, and <jats:italic>T<\/jats:italic>. <jats:italic>cruzi<\/jats:italic> genotyping for <jats:italic>T<\/jats:italic>. <jats:italic>dimidiata<\/jats:italic> specimens collected in nine municipalities in Boyac\u00e1 and explored <jats:italic>T<\/jats:italic>. <jats:italic>dimidiata<\/jats:italic> population genetics. We found that <jats:italic>T<\/jats:italic>. <jats:italic>dimidiata<\/jats:italic> populations are composed by a single population with similar genetic characteristics that present infection rates up to 70%, high parasite loads up to 1.46 \u00d7 10<jats:sup>9<\/jats:sup> parasite-equivalents\/mL, a feeding behavior that comprises at least 17 domestic, synanthropic and sylvatic species, and a wide diversity of TcI genotypes even within a single specimen. These results imply that <jats:italic>T<\/jats:italic>. <jats:italic>dimidiata<\/jats:italic> behavior is similar to other successful vectors, having a wide variety of blood sources and contributing to the circulation of different genotypes of the parasite, highlighting its importance for <jats:italic>T<\/jats:italic>. <jats:italic>cruzi<\/jats:italic> transmission and risk for humans. In the light of the elimination of <jats:italic>R<\/jats:italic>. <jats:italic>prolixus<\/jats:italic> in Boyac\u00e1 and the results we found, we suggest that <jats:italic>T<\/jats:italic>. <jats:italic>dimidiata<\/jats:italic> should become a new target for vector control programs. We hope this study provides enough information to enhance surveillance programs and a future effective interruption of <jats:italic>T<\/jats:italic>. <jats:italic>cruzi<\/jats:italic> vector transmission in endemic regions.<\/jats:p>","DOI":"10.1371\/journal.pntd.0010534","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T17:34:48Z","timestamp":1657560888000},"page":"e0010534","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":14,"title":["Estimating the genetic structure of Triatoma dimidiata (Hemiptera: Reduviidae) and the transmission dynamics of Trypanosoma cruzi in Boyac\u00e1, eastern Colombia"],"prefix":"10.1371","volume":"16","author":[{"given":"Natalia","family":"Vel\u00e1squez-Ortiz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Cantillo-Barraza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Medina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mabel","family":"Medina-Alfonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Suesc\u00fan-Carrero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Vega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Casta\u00f1eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lissa","family":"Cruz-Saavedra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathalia","family":"Ballesteros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1344-9312","authenticated-orcid":true,"given":"Juan David","family":"Ram\u00edrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2022,7,11]]},"reference":[{"issue":"2","key":"pntd.0010534.ref001","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.idc.2012.03.002","article-title":"American trypanosomiasis (Chagas disease).","volume":"26","author":"A Rassi","year":"2012","journal-title":"J Infect Dis Clin North Am"},{"key":"pntd.0010534.ref002","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.actatropica.2017.05.005","article-title":"Trypanosoma cruzi I: Towards the need of genetic subdivision?","volume":"184","author":"J Ram\u00edrez","year":"2018","journal-title":"Part II. 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