{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T03:48:16Z","timestamp":1785383296895,"version":"3.55.0"},"reference-count":71,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:00:00Z","timestamp":1682553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p><jats:italic>Paracoccidioides<\/jats:italic> species have always been surrounded by taxonomic uncertainties. The continuing nomenclatoral muddle was caused in part by the failure of Adolfo Lutz and Jorge L\u00f4bo to name the etiologic agents of human paracoccidioidomycosis and Jorge L\u00f4bo\u2019s diseases, respectively. Early in their history, it was postulated that the cultivable species causing systemic infections belonged in the genus <jats:italic>Paracoccidioides<\/jats:italic>, whereas the uncultivable species, causing skin disease, were not part of the genus. The taxonomy of these pathogens was further complicated when a similar skin disease with numerous yeast-like cells in infected dolphins was also reported. Due to its phenotypic similarities with that described by Jorge L\u00f4bo in human and its uncultivable nature, it was assumed that the disease in dolphins was caused by the same fungus. Recent molecular and population genetic analysis, however, found the DNA extracted from the uncultivable yeast-like cells affecting dolphins shared common phylogenetic traits with cultivable <jats:italic>Paracoccidioides<\/jats:italic> species. The study revealed that the uncultivable pathogens comprised 2 different <jats:italic>Paracoccidioides<\/jats:italic> species, now known as <jats:italic>P<\/jats:italic>. <jats:italic>ceti<\/jats:italic> and <jats:italic>P<\/jats:italic>. <jats:italic>loboi<\/jats:italic>, correspondingly. To validate <jats:italic>P<\/jats:italic>. <jats:italic>loboi<\/jats:italic> binomial, a comprehensive historical critical review of Jorge L\u00f4bo etiology was performed. This review showed the proposed binomial <jats:italic>P<\/jats:italic>. <jats:italic>loboi<\/jats:italic> was previously used, and, thus, a replacement name is introduced, <jats:italic>Paracoccidioides lobogeorgii<\/jats:italic> nom. nov. In addition, in this review, several cultivable human <jats:italic>Paracoccidioides<\/jats:italic> species are validated, and the generic type species, <jats:italic>P<\/jats:italic>. <jats:italic>brasiliensis<\/jats:italic>, is neotypified as the original material could not be traced.<\/jats:p>","DOI":"10.1371\/journal.pntd.0011220","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T17:25:00Z","timestamp":1682616300000},"page":"e0011220","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":46,"title":["A taxonomic review of the genus Paracoccidioides, with focus on the uncultivable species"],"prefix":"10.1371","volume":"17","author":[{"given":"Raquel","family":"Vilela","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sybren","family":"de Hoog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstanze","family":"Bensch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Bagagli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7769-2151","authenticated-orcid":true,"given":"Leonel","family":"Mendoza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,4,27]]},"reference":[{"key":"pntd.0011220.ref001","first-page":"121","article-title":"Uma micose psedococcidica localisada na bocca e observada no Brasil. 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