{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:54:03Z","timestamp":1792623243055,"version":"4.5.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0011244","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T00:00:00Z","timestamp":1681344000000}}],"reference-count":45,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T00:00:00Z","timestamp":1680480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000774","name":"Defense Threat Reduction Agency","doi-asserted-by":"publisher","award":["HDTRA1-08-D-0007"],"award-info":[{"award-number":["HDTRA1-08-D-0007"]}],"id":[{"id":"10.13039\/100000774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["220211"],"award-info":[{"award-number":["220211"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>\n                    In Cambodia, goat production and meat consumption are customary among Muslim communities. Recently, goat meat has gained popularity among Cambodians. Goat farmers use a traditional management system, including grazing, requiring minimal labour. The close proximity between humans and animals could increase the risk of zoonotic disease transmission. A serological survey was undertaken to estimate the prevalence of some priority zoonoses and high-impact animal diseases in the Cambodian goat population. A total of 540 samples were collected from goats in six provinces and analysed with commercially available enzyme-linked immunosorbent assays for\n                    <jats:italic>Brucella<\/jats:italic>\n                    species, Q fever (C\n                    <jats:italic>oxiella burnetii<\/jats:italic>\n                    ), Foot and Mouth Disease virus non-structural protein (FMDV NSP) and Peste des Petits Ruminants virus (PPRV). True seroprevalences with a 95% Confidence Interval (CI), taking into account imperfect tests, risk factors and odds ratios (ORs), were calculated to better understand the disease distribution and epidemiology. Independent variables used in statistical modellings included sex, body condition score, age, vaccination history, province and commune, while dependent variables were ELISA test results. The overall true prevalence of antibodies to\n                    <jats:italic>Brucella spp<\/jats:italic>\n                    .,\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>burnetii<\/jats:italic>\n                    , FMDV and PPRV, were 0.1% (95% CI 0.0, 1.0), 7.2% (95% CI 5.3, 9.7), 57.7% (95% CI 53.1, 62.3) and 0.0% (95% CI 0.0, 0.0), respectively. There was no identified risk factor for brucellosis and PPR. The two risk factors for\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>burnetii<\/jats:italic>\n                    seropositivity were sex (p-value = 0.0005) and commune (p-value &lt;0.0001). However, only the OR of\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>burnetii<\/jats:italic>\n                    seropositive female goat was significant at 9.7 (95% CI 2.7, 35.5) times higher than male. The risk factors of FMD NSP seropositivity were age (p-value = 0.001) and commune (p-value &lt;0.0001). Only the age \u2019more than two-year-old\u2019 group with a significant OR of 6.2 (95% CI 2.1, 18.4) using the \u2019up to one-year-old\u2019 group as the reference. In summary,\n                    <jats:italic>Brucella spp<\/jats:italic>\n                    . seroprevalence was low, while no evidence of PPRV antibodies was detected in the goat populations.\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>burnetii<\/jats:italic>\n                    seroprevalence in female goats was significantly higher than for males, and there were significant differences in\n                    <jats:italic>C<\/jats:italic>\n                    .\n                    <jats:italic>burnetii<\/jats:italic>\n                    seroprevalence between communes. The overall FMDV NSP seroprevalence was high, especially in older animals. Vaccination should be advocated to protect animals from FMDV and improve productivity. As the impacts of these zoonoses on human and animal health were still unknown, further investigation of these zoonotic diseases\u2019 epidemiology is recommended.\n                  <\/jats:p>","DOI":"10.1371\/journal.pntd.0011244","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T14:11:25Z","timestamp":1680531085000},"page":"e0011244","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":17,"title":["Risk mapping using serologic surveillance for selected One Health and transboundary diseases in Cambodian goats"],"prefix":"10.1371","volume":"17","author":[{"given":"Jarunee","family":"Siengsanan-Lamont","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lida","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theng","family":"Heng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sokun","family":"Khoeun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sothyra","family":"Tum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Selleck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence J.","family":"Gleeson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6576-726X","authenticated-orcid":true,"given":"Stuart D.","family":"Blacksell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,4,3]]},"reference":[{"key":"pntd.0011244.ref001","unstructured":"General Directorate of Animal Health and Production (GDAHP). 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