{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T11:30:46Z","timestamp":1767180646565,"version":"build-2238731810"},"update-to":[{"DOI":"10.1371\/journal.pntd.0012101","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T00:00:00Z","timestamp":1714003200000}}],"reference-count":55,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T00:00:00Z","timestamp":1713139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Schistosomiasis is endemic in Nigeria, and the treatment is largely concentrated on children enrolled in schools. Consequently, the coverage of non-enrolled school-aged children is often neglected. Ajagba and Awosan are two communities in Nigeria that have never had any control intervention. Hence, this survey was designed to determine the endemicity of urogenital schistosomiasis and to evaluate the efficacy of a single-dose praziquantel in the communities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Urine sample (10 mL) of each participant from Ajagba and Awosan communities was filtered through 12\u03bcm polycarbonate filter. The filter was placed on a microscope slide, and stained with a drop of 1% Lugol iodine solution. The stained slides were examined under the microscope and the numbers of\n                      <jats:italic>S<\/jats:italic>\n                      .\n                      <jats:italic>haematobium<\/jats:italic>\n                      eggs were counted. Water contact sites were searched for snail hosts and the snails collected were shed for\n                      <jats:italic>Schistosoma<\/jats:italic>\n                      cercariae. Data were analyzed using SPSS version 24.0 and the significance level was set at 95%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The overall prevalence of infection in the Ajagba community was 45.6% with a mean intensity of 61.1 \u00b1 144.5 eggs\/10 mL of urine, while the prevalence of infection in the Awosan community was 5.7% with a mean intensity of 1.4 \u00b1 6.8 eggs\/10 mL of urine. The school-aged children had a prevalence and mean intensity of infection of 73.1% and 111.6 \u00b1 177.9 eggs\/10 mL of urine, respectively. Following treatment, women had a higher egg reduction rate than men (p = 0.0283).\n                      <jats:italic>Bulinus globosus<\/jats:italic>\n                      were found in Ajagba but not in Awosan, with 5.7% shedding\n                      <jats:italic>Schistosoma<\/jats:italic>\n                      spp, cercariae.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Urogenital schistosomiasis was hyperendemic in the Ajagba community, and hypoendemic in the Awosan community. The presence of\n                      <jats:italic>Bulinus globosus<\/jats:italic>\n                      supported the transmission of the schistosomiasis in the Ajagba community. Communities where schistosomiasis is still actively transmitted in Nigeria should be identified for effective intervention through the MDA programs.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pntd.0012101","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T13:24:21Z","timestamp":1713187461000},"page":"e0012101","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Endemic status of urogenital schistosomiasis and the efficacy of a single-dose praziquantel treatment in unmapped rural farming communities in Oyo East Local Government Area, Oyo State, Nigeria"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9743-9751","authenticated-orcid":true,"given":"Alexander B.","family":"Odaibo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adenike K.","family":"Komolafe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiwo O.","family":"Olajumoke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanyinsola D.","family":"Diyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damilare A.","family":"Aluko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oluwatunmininu A.","family":"Alagbe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oluwafemi A.","family":"Ajagbe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Olarinloye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,4,15]]},"reference":[{"key":"pntd.0012101.ref001","unstructured":"World Health Organization (WHO). 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