{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T11:55:42Z","timestamp":1767182142526,"version":"build-2238731810"},"update-to":[{"DOI":"10.1371\/journal.pntd.0012784","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T00:00:00Z","timestamp":1736294400000}}],"reference-count":76,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T00:00:00Z","timestamp":1735171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"This research was funded through a grant awarded by WINDREF at SGU, Grenada, West Indies."}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>\n                    Leptospirosis is a spirochetal disease caused by\n                    <jats:italic>Leptospira<\/jats:italic>\n                    spp. bacteria with global distribution affecting multiple mammalian species, including humans. The disease is endemic in many geographic areas and is of particular concern in tropical regions with abundant rainfall, such as the Caribbean. Currently, there are no published reports on\n                    <jats:italic>Leptospira<\/jats:italic>\n                    exposure or infection in Grenadian cat populations, and the role of cats in the epidemiology of the disease is unknown. Our hypothesis is that Grenadian cat population may be a reservoir host for zoonotic\n                    <jats:italic>Leptospira<\/jats:italic>\n                    on the island. During 2019\u20132021, 160 feral cats were captured from three parishes in Grenada, and their urine and blood were tested for\n                    <jats:italic>Leptospira<\/jats:italic>\n                    . Urine from 4 of 148 (2.7%) cat samples tested PCR-positive for\n                    <jats:italic>Leptospira<\/jats:italic>\n                    . Serum from 6 of 136 (4.4%) cat samples tested PCR-positive for\n                    <jats:italic>Leptospira<\/jats:italic>\n                    . Sequence analysis of the\n                    <jats:italic>Leptospira rpoB<\/jats:italic>\n                    gene showed 86\u2013100% similarity to known or presumed pathogenic\n                    <jats:italic>Leptospira<\/jats:italic>\n                    species. The findings of this study suggest that Grenadian cat populations are infected with and are shedding\n                    <jats:italic>Leptospira<\/jats:italic>\n                    genotypes that are phylogenetically related to known pathogenic\n                    <jats:italic>Leptospira<\/jats:italic>\n                    , including known zoonotic strains. These observations support the hypothesis that Grenadian cat populations may be a reservoir host for zoonotic\n                    <jats:italic>Leptospira<\/jats:italic>\n                    on the Island.\n                  <\/jats:p>","DOI":"10.1371\/journal.pntd.0012784","type":"journal-article","created":{"date-parts":[[2024,12,26]],"date-time":"2024-12-26T13:43:02Z","timestamp":1735220582000},"page":"e0012784","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Grenadian cats as potential reservoir for Leptospira"],"prefix":"10.1371","volume":"18","author":[{"given":"Keith K.","family":"Kalasi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Fitzpatrick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Stone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Talia","family":"Guttin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4766-7991","authenticated-orcid":true,"given":"Andy","family":"Alhassan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,12,26]]},"reference":[{"issue":"3\u20134","key":"pntd.0012784.ref001","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.vetmic.2009.03.012","article-title":"Leptospira and leptospirosis","volume":"140","author":"B 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