{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T22:47:02Z","timestamp":1791758822837,"version":"4.3.4"},"update-to":[{"DOI":"10.1371\/journal.pntd.0013026","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:00:00Z","timestamp":1773964800000}}],"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ratchadapiseksomphot Fund, Faculty of Medicine, Chulalongkorn University","award":["RA67\/027 and RA-MF20\/67"],"award-info":[{"award-number":["RA67\/027 and RA-MF20\/67"]}]},{"DOI":"10.13039\/501100003762","name":"Institut Pasteur","doi-asserted-by":"publisher","award":["ANR-19-CE03-0004-02"],"award-info":[{"award-number":["ANR-19-CE03-0004-02"]}],"id":[{"id":"10.13039\/501100003762","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Dengue and chikungunya, both transmitted by\n                      <jats:italic>Aedes<\/jats:italic>\n                      mosquitoes, continue to pose significant public health concerns in Thailand, particularly during the rainy season. Despite ongoing vector control efforts, the incidence of infection remains high, with an increasing trend observed in chikungunya. This underscores the need for additional control measures, including vaccination, to reduce disease burden and morbidity. This study aims to assess the seroprevalence of dengue and chikungunya infections among children aged 10\u201315 years in Bangkok and to evaluate the knowledge, attitudes, and practices (KAP) related to mosquito-borne disease prevention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>A cross-sectional descriptive study was conducted across 12 schools in Bangkok. Children aged 10\u201315 years were included. Seroprevalence was determined using rapid diagnostic tests (Abbott DENGUE IgG\/IgM and Citest Chikungunya IgG\/IgM) based on the immunochromatography technique, using fingertip blood samples. Parents completed KAP questionnaires, including factors influencing vaccination decisions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Principal findings<\/jats:title>\n                    <jats:p>From June to August 2024, 937 participants were enrolled, with a mean (SD) age of 11 (1.6) years; 67% were aged 10\u201312 years, and 33% were aged 13\u201315 years. The seroprevalence of dengue was 28.1% (95% CI 25.2-31.0), while that of chikungunya was 6.3% (95% CI 4.7-7.9). KAP assessments revealed a high level of awareness regarding symptoms and transmission; however, notable deficiencies in preventive behaviors were identified. Only 14.8% of respondents reported consistent use of mosquito repellent, and 17.5% routinely inspected and removed mosquito larvae from their homes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The substantial seroprevalence of dengue and the emerging trend of chikungunya among children in Bangkok highlights the urgent need to enhance community education and strengthen vector control interventions. Expanding dengue vaccination coverage and raising awareness about chikungunya prevention, including consideration for future vaccine implementation, are essential to mitigating future outbreaks and reducing the disease burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec005\">\n                    <jats:title>Trial registration<\/jats:title>\n                    <jats:p>\n                      Thai Clinical Trials under the number TCTR20240404002 (\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.thaiclinicaltrials.org\/show\/TCTR20240404002\" xlink:type=\"simple\">https:\/\/www.thaiclinicaltrials.org\/show\/TCTR20240404002<\/jats:ext-link>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pntd.0013026","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T17:29:33Z","timestamp":1773682173000},"page":"e0013026","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Seroprevalence and preventive practices of dengue and chikungunya among school children in Bangkok: Gaps in prevention and vaccination strategies"],"prefix":"10.1371","volume":"20","author":[{"given":"Thitiya","family":"Yakasaem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thidarat","family":"Jupimai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nattapong","family":"Jitrungruengnij","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Napaporn","family":"Chantasrisawad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekasit","family":"Kowitdamrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padet","family":"Siriyasatien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunthorn","family":"Sunthornchart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nattinee","family":"Isarankura Na Ayudaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paveena","family":"Angkhananukit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pitsamai","family":"Ruansil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanchana","family":"Nakhapakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Daud\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Cebeillac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanyawee","family":"Puthanakit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4251-3499","authenticated-orcid":true,"given":"Watsamon","family":"Jantarabenjakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,3,16]]},"reference":[{"key":"pntd.0013026.ref001","unstructured":"Department of Disease Control. Dengue situation in Thailand [internet]. 2024 [cited 2024 Oct]."},{"key":"pntd.0013026.ref002","unstructured":"Division of Vector-Borne Diseases, Department of Diseases Control. Dengue situation in Bangkok [internet]. 2024 [cited 2024 Oct]. Available from: https:\/\/webportal.bangkok.go.th"},{"issue":"12","key":"pntd.0013026.ref003","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0010966","article-title":"Epidemiology and costs of dengue in Thailand: A systematic literature review","volume":"16","author":"U Thisyakorn","year":"2022","journal-title":"PLoS Negl Trop Dis"},{"issue":"12","key":"pntd.0013026.ref004","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1056\/NEJMoa1503877","article-title":"Symptomatic Dengue in Children in 10 Asian and Latin American Countries","volume":"374","author":"M L\u2019Azou","year":"2016","journal-title":"N Engl J Med"},{"key":"#cr-split#-pntd.0013026.ref005.1","unstructured":"Division of Epidemioloy, Department of Disease Control. 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Vaccines and immunization: Dengue. 2024 May 10 [cited 2025 May 21]. Available from: https:\/\/www.who.int\/news-room\/questions-and-answers\/item\/dengue-vaccines"},{"key":"pntd.0013026.ref011","unstructured":"World Health Organization. Dengue vaccine safety update. 2018 January 19 [cited 2025 August 14]. Available from: https:\/\/www.who.int\/groups\/global-advisory-committee-on-vaccine-safety\/topics\/dengue-vaccines\/safety-update"},{"key":"pntd.0013026.ref012","unstructured":"Control UCoD. Chikungunya vaccine information for healthcare providers. 2024 May 20 [cited 2025 Mar 21]. Available from: https:\/\/www.cdc.gov\/chikungunya\/hcp\/vaccine\/index.html"},{"key":"pntd.0013026.ref013","unstructured":"Abbott. Bioline DENGUE IgG\/IgM WB 2024 [cited 2025 Mar 21] Available from: https:\/\/www.globalpointofcare.abbott\/pk\/en\/product-details\/bioline-dengue-igg-igm.html"},{"key":"pntd.0013026.ref014","unstructured":"Citest Diagnostics INC. Chikungunya IgG\/IgM Rapid Test. 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