{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:01:43Z","timestamp":1762300903066,"version":"3.40.5"},"reference-count":57,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T00:00:00Z","timestamp":1746662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Soil-transmitted helminthiasis and Schistosomiasis are major public health problems mainly among school-age children. Despite the seven years of implementing elimination program, the ongoing prevalence and intensity of both diseases have not been assessed in the study area. Hence, this study aimed to determine the parasitological indicator (prevalence and intensity) of soil-transmitted helminths and <jats:italic>Schistosoma mansoni<\/jats:italic> infections after seven years of preventive chemotherapy among school-age children in Mizan-Aman town.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>A cross-sectional study was conducted among 615 school-age children from January to February 2022 in Mizan-Aman Town. Study participants were selected using a systematic random sampling technique. Sociodemographic and associated factors were collected using a structured questionnaire. The stool samples were collected and processed using the double-slide Kato-Katz technique. The parasitological indicator was evaluated based on the thresholds set by the elimination program.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The overall prevalence of soil-transmitted helminths infection was 50.7% (95% CI: 46.8-54.8); with 2.4% moderate and heavy intensity, and <jats:italic>Schistosoma mansoni<\/jats:italic> infection prevalence was 25.4% (95% CI: 22.1-28.6), with 3.3% heavy intensity infection. School-age children in public schools; AOR: 3.92, (95% CI: 2.33-6.60), drinking river water; AOR: 1.79, (95% CI: 1.08-2.98), irregular handwashing before meals; AOR: 3.18, (95% CI: 1.24-8.35), eating unwashed fruits; AOR: 2.47, (95% CI: 1.56-3.92), and habits of soil contact; AOR: 2.48, (95% CI: 1.69-3.62), were associated factors for soil-transmitted helminths infection, whereas river swimming habits; AOR: 3.46, (95% CI: 2.18-5.50), bathing in the river; AOR: 3.29, (95% CI: 2.18-5.50), male gender; AOR: 1.72, (95% CI: 1.15-2.58), and school-age children in public schools; AOR: 2.36, 95% CI (1.19-4.68), were predictors of <jats:italic>Schistosoma mansoni<\/jats:italic> infection.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Despite the preventive chemotherapy that has been implemented in the study area, the prevalence of soil-transmitted helminths and <jats:italic>Schistosoma mansoni<\/jats:italic> infections persist at a high level. Hence, the preventive chemotherapy implementation could be revised and integrated with other control strategies for elimination.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pntd.0013058","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T17:51:58Z","timestamp":1746726718000},"page":"e0013058","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessing soil-transmitted helminths and Schistosoma mansoni infections using parasitological indicators after seven years of preventive chemotherapy among school-age children in Mizan-Aman town"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2210-8020","authenticated-orcid":true,"given":"Mitiku","family":"Abera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tariku","family":"Belay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Emana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeleke","family":"Mekonnen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,5,8]]},"reference":[{"key":"pntd.0013058.ref001","volume-title":"Investing and overcoming the global impact of neglected tropical disease: 3rd WHO report","author":"World Health Organization","year":"2015"},{"key":"pntd.0013058.ref002","volume-title":"Eliminating soil-transmitted helminthiasis as a public health problem in children: progress report 2001\u20132010 and strategic plan 2011-2020","author":"World Health Organization","year":"2020"},{"key":"pntd.0013058.ref003","volume-title":"The social context of schistosomiasis and its control","author":"World Health Organization","year":"2008"},{"issue":"2","key":"pntd.0013058.ref004","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.bjid.2014.11.004","article-title":"Impact of human schistosomiasis in sub-Saharan Africa","volume":"19","author":"AF Adenowo","year":"2015","journal-title":"Braz J Infect Dis"},{"key":"pntd.0013058.ref005","volume-title":"Guideline on control and elimination of human schistosomiasis","author":"World Health Organization","year":"2022"},{"key":"pntd.0013058.ref006","volume-title":"Ending the neglect to attain the Sustainable Development Goals A road map for neglected tropical diseases 2021 \u2013 2030","author":"World Health Organization","year":"2020"},{"issue":"50","key":"pntd.0013058.ref007","first-page":"601","article-title":"Schistosomiasis and soil- transmitted helminthiases: numbers of people treated in 2018","volume":"94","author":"World Health Organization","year":"2019","journal-title":"Weekly Epidemiological Record"},{"key":"pntd.0013058.ref008","volume-title":"Helminth control in school-age children: A guide for managers of control programs. 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