{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T11:10:33Z","timestamp":1767179433941,"version":"build-2238731810"},"update-to":[{"DOI":"10.1371\/journal.pntd.0013408","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T00:00:00Z","timestamp":1755475200000}}],"reference-count":19,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T00:00:00Z","timestamp":1754870400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000200","name":"United States Agency for International Development","doi-asserted-by":"publisher","award":["NTDSC 241U"],"award-info":[{"award-number":["NTDSC 241U"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Trachoma remains a significant public health issue in many regions, including Baringo County, Kenya. Despite the ongoing mass drug administration (MDA) campaigns in Baringo, the achievement of optimal treatment coverage has been hindered by factors such as conflicts and the nomadic lifestyle dominating this region. To address these challenges, innovative strategies are needed to improve community engagement and enhance MDA uptake. This study evaluated the effectiveness of community participation approaches in improving MDA access among residents of Baringo County.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study used a pre- and post-intervention design, utilizing a systematic random sampling of households. The study area was Loyamorok Ward, Tiaty East Sub-County in Baringo County. The county was purposively selected due to its historical challenges in achieving optimal treatment coverage for trachoma, including its nomadic lifestyle, intercounty border movements, and persistent conflicts. A sample of 350 respondents was randomly selected for the pre- and post-intervention surveys. Data were collected using a structured questionnaire, which captured information on socio-demographic and socio-economic characteristics, knowledge about trachoma and MDA, drug use, and perceptions of the treatment. Generalized linear models were employed to estimate the likelihood of MDA access before and after the intervention and the impact of the intervention, which incorporated time difference as an interaction term in the models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Principal findings<\/jats:title>\n                    <jats:p>The results indicated a significant increase in community participation and MDA access, with the proportion of participants who took drugs during the last MDA significantly rising from 72.4% pre-intervention to 92.9% post-intervention (Diff\u2009=\u2009-0.205, z\u2009=\u2009-5.68, p\u2009&lt;\u20090.001). Type of occupation was found to significantly impact access to MDA for trachoma, participants doing pastoral activities (aOR = 11.45, 95% CI: 1.15-114.14, p\u2009=\u20090.038), and those who were not engaged in work outside the home (housewife) (aOR = 12.87, 95% CI: 1.09-151.52, p\u2009=\u20090.042) showed significant increased access to MDA compared to salaried workers. The study showed that knowledge about trachoma and MDA significantly improved after the implementation of the interventions. Awareness about MDA increased from 45.7% during pre-intervention to 53.3% post-intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that the implemented community participation strategies positively influenced MDA uptake. The implemented interventions should be considered for wider application to enhance treatment coverage and accelerate trachoma elimination efforts in Kenya.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pntd.0013408","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T17:41:23Z","timestamp":1754934083000},"page":"e0013408","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing the effectiveness of the community participation approaches to improve access to mass drug administration for trachoma elimination in a pastoral conflict area of Baringo County, Kenya"],"prefix":"10.1371","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2647-1359","authenticated-orcid":true,"given":"Collins","family":"Okoyo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Kopi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul M.","family":"Gichuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bridget W.","family":"Kimani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tabitha","family":"Kanyui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Titus","family":"Waititu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wyckliff P.","family":"Omondi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doris W.","family":"Njomo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"issue":"2","key":"pntd.0013408.ref001","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009131","article-title":"The impact of Neglected Tropical Diseases (NTDs) on health and wellbeing in sub-Saharan Africa (SSA): A case study of Kenya","volume":"15","author":"EA Ochola","year":"2021","journal-title":"PLoS Negl Trop Dis"},{"issue":"3","key":"pntd.0013408.ref002","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/14787210.2019.1577136","article-title":"Ocular Chlamydia trachomatis infection: elimination with mass drug administration","volume":"17","author":"MA Wolle","year":"2019","journal-title":"Expert Rev Anti Infect 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Zithromax Dosing Guidelines 2020 Updated Version. 2018."},{"key":"pntd.0013408.ref014","volume-title":"2019 Kenya Population and Housing Census","author":"Kenya National Bureau of Statistics","year":"2019"},{"issue":"11","key":"pntd.0013408.ref015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0012653","article-title":"Using community-based participatory approaches to improve access to mass drug administration for trachoma elimination in a pastoral conflict area of Kenya","volume":"18","author":"PM Gichuki","year":"2024","journal-title":"PLoS Negl Trop Dis"},{"issue":"11","key":"pntd.0013408.ref016","doi-asserted-by":"crossref","DOI":"10.1016\/S2214-109X(20)30344-2","article-title":"Patterns of individual non-treatment during multiple rounds of mass drug administration for control of soil-transmitted helminths in the TUMIKIA trial, Kenya: a secondary longitudinal analysis","volume":"8","author":"WE Oswald","year":"2020","journal-title":"Lancet Glob Health"},{"key":"pntd.0013408.ref017","unstructured":"Republic of Kenya, Ministry of Health. Lymphatic Filariasis Double Therapy (DA) Mass Drug Administration. A handbook for CDDs: Revised copy. 2019, 14 p."},{"issue":"5","key":"pntd.0013408.ref018","article-title":"Improving drug delivery strategies for lymphatic filariasis elimination in urban areas in Ghana","volume":"11","author":"N-K Biritwum","year":"2017","journal-title":"PLoS Negl Trop Dis"},{"issue":"11","key":"pntd.0013408.ref019","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0007861","article-title":"How community engagement strategies shape participation in mass drug administration programmes for lymphatic filariasis: The case of Luangwa District, Zambia","volume":"13","author":"A Silumbwe","year":"2019","journal-title":"PLoS Negl Trop Dis"}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0013408","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T00:00:00Z","timestamp":1755475200000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0013408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T18:15:19Z","timestamp":1755540919000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0013408"}},"subtitle":[],"editor":[{"given":"Elsio A","family":"Wunder Jr","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2025,8,11]]},"references-count":19,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2025,8,11]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0013408","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,11]]}}}