{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T11:55:46Z","timestamp":1767182146832,"version":"build-2238731810"},"update-to":[{"DOI":"10.1371\/journal.pntd.0013644","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000}}],"reference-count":16,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["INV-045988"],"award-info":[{"award-number":["INV-045988"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to estimate the prevalence of shigellosis among household contacts (HHCs) using data from the \u2018Enterics for Global Health (EFGH)\u2019 study, conducted at seven Asian and African countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In Bangladesh, the EFGH study was conducted in Maniknagar, Dhaka, to determine the burden of shigellosis among children aged 6\u201335 months. HHCs of\n                      <jats:italic>\n                        <jats:italic>Shigella<\/jats:italic>\n                      <\/jats:italic>\n                      -positive patients (index cases) were enrolled in this study. Stool specimens form contacts were collected within 7 days of enrollment of index cases and culture and qPCR were performed. Sociodemographic and behavioral information were obtained to identify risk factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 400 HHCs of 118 index cases were enrolled, of which 36 (9%) were positive for\n                      <jats:italic>\n                        <jats:italic>Shigella<\/jats:italic>\n                      <\/jats:italic>\n                      spp. by culture, while qPCR revealed 21% (42\/200) of contacts had\n                      <jats:italic>\n                        <jats:italic>Shigella<\/jats:italic>\n                      <\/jats:italic>\n                      infections. Individuals who failed to reheat meals before consumption had a two-fold higher risk of shigellosis compared to those who reheated meals, although other sociodemographic and behavioral factors did not show any significant association.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The study revealed a high burden of asymptomatic\n                      <jats:italic>\n                        <jats:italic>Shigella<\/jats:italic>\n                      <\/jats:italic>\n                      -infected individuals, emphasizing the need for systematic surveillance to assess the burden and develop effective preventive strategies to prevent the spread of the disease.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pntd.0013644","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T18:40:07Z","timestamp":1762454407000},"page":"e0013644","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of Shigellosis among household contacts of index cases in the EFGH catchment area, Dhaka, Bangladesh"],"prefix":"10.1371","volume":"19","author":[{"given":"Md Taufiqul","family":"Islam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farhana","family":"Khanam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Nazmul Hasan","family":"Rajib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Ismail","family":"Hossen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed","family":"Qudrat-E-Khuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahzabeen","family":"Ireen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md Golam","family":"Firoj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal","family":"Ahmmed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prasanta Kumar","family":"Biswas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amirul Islam","family":"Bhuiyan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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