{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T18:57:05Z","timestamp":1774033025983,"version":"3.50.1"},"update-to":[{"DOI":"10.1371\/journal.pntd.0014079","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:00:00Z","timestamp":1773964800000}}],"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:00:00Z","timestamp":1773273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1139661"],"award-info":[{"award-number":["APP1139661"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP2025815"],"award-info":[{"award-number":["APP2025815"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Hookworms remain problematic in Dak Lak province, Vietnam, despite a school preventive chemotherapy (PC) program since 2007. As hookworms depend on favourable ecological conditions, geospatial modelling incorporating environmental and climatic variables can predict high-risk areas for targeted interventions. This study provides geospatial risk predictions for hookworm infection and intensity among school-aged children in Dak Lak.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Hookworm infection status and intensity from 7,964 school-aged children from 64 schools collected in 2019\u20132020 during the Community Deworming for STH trial was combined with environmental and climatic data to develop risk prediction models for (i) overall hookworm infection and (ii) moderate-and-heavy intensity (MHI)\n                      <jats:italic>Necator americanus<\/jats:italic>\n                      infection. Environmental and climatic predictors for the multivariable generalised linear models were selected by identifying the model with the lowest Akaike Information Criterion. Semivariograms were examined for residual spatial autocorrelation, and if present, was accounted for using Mat\u00e9rn\u2019s covariance. Regression coefficients were used to predict overall hookworm and MHI\n                      <jats:italic>N. americanus<\/jats:italic>\n                      infection risk across Dak Lak province pre- and post-intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Temperature, precipitation, soil and vegetation variables were included in the hookworm model, while temperature and precipitation variables were included in the MHI\n                      <jats:italic>N. americanus<\/jats:italic>\n                      model. Most of Dak Lak had a predicted hookworm risk of 10\u201315% pre- and post-intervention, with high-risk hotspots in southern and eastern parts. Moderate-and-heavy intensity\n                      <jats:italic>N. americanus<\/jats:italic>\n                      infection risk pre-intervention was higher than 2% throughout the province and considerably reduced to small pockets in southeastern, central and northern areas post-intervention.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>School-based PC should be delivered across Dak Lak at least annually, in keeping with World Health Organization recommendations. However, several hotspots have been identified that would benefit from increased frequency of school-based PC or community-wide mass drug administration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pntd.0014079","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T17:36:22Z","timestamp":1773336982000},"page":"e0014079","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Geospatial risk prediction of hookworm infection and intensity among school-aged children in Dak Lak province, Vietnam"],"prefix":"10.1371","volume":"20","author":[{"given":"Tin N. 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