{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T18:18:24Z","timestamp":1788373104366,"version":"build-2803163510"},"update-to":[{"DOI":"10.1371\/journal.pntd.0014201","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000}}],"reference-count":46,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T00:00:00Z","timestamp":1787529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"crossref","award":["APQ-04991-23"],"award-info":[{"award-number":["APQ-04991-23"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>\n                    Dengue transmission is strongly influenced by climatic conditions that affect mosquito population dynamics and virus circulation. In Southern Brazil, where dengue historically occurred at low levels, recent climatic anomalies may be contributing to the expansion of\n                    <jats:italic>Aedes<\/jats:italic>\n                    vectors and increased local dengue incidence. This study investigated the spatiotemporal association between climatic variables,\n                    <jats:italic>Aedes<\/jats:italic>\n                    infestation and dengue cases in Porto Alegre (Southern Brazil, from 2018 to 2025). Entomological, surveillance and climatic data were analyzed using Moran\u2019s I and LISA for spatial association, Kendall correlation, polynomial regression and LASSO to identify relevant drivers and develop predictive models of mosquito infestation and dengue incidence. Strong spatial association between\n                    <jats:italic>Aedes aegypti<\/jats:italic>\n                    and\n                    <jats:italic>Aedes albopictus<\/jats:italic>\n                    was observed, with persistent local clusters detected across all years. Annual climatic variables were associated with mosquito abundance in several districts. Overall, rainfall frequency had a stronger effect on\n                    <jats:italic>Ae. aegypti<\/jats:italic>\n                    abundance than accumulated rainfall. Temperature and lagged infestation indices showed strong associations with both species and dengue incidence, with lag effects detected up to eight weeks. Predictive models demonstrated good agreement between observed and predicted values, particularly at low to moderate infestation levels. Lagged variables were consistently retained in both mosquito abundance and dengue incidence models, highlighting the importance of temporal predictors in anticipating vector dynamics and dengue risk. This approach is broadly applicable for predicting\n                    <jats:italic>Aedes<\/jats:italic>\n                    infestation and disease incidence and it underscores the importance of integrating entomological and climatic surveillance data to enhance anticipation and early detection of dengue risk periods in large urban settings and inform more effective public health interventions.\n                  <\/jats:p>","DOI":"10.1371\/journal.pntd.0014201","type":"journal-article","created":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T17:38:57Z","timestamp":1787593137000},"page":"e0014201","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Climate-driven spatiotemporal dynamics of Aedes infestation and dengue transmission in Porto Alegre, Southern Brazil"],"prefix":"10.1371","volume":"20","author":[{"given":"Adryan Aparecido","family":"da Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1lvaro Gil Araujo","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Louren\u00e7o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8600-4077","authenticated-orcid":true,"given":"Amanda","family":"Cupertino de Freitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"pntd.0014201.ref001","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3389\/fcimb.2017.00317","article-title":"Global epidemiology of dengue outbreaks in 1990-2015: a systematic review and meta-analysis","volume":"7","author":"C Guo","year":"2017","journal-title":"Front Cell Infect 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