{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T12:39:50Z","timestamp":1782823190143,"version":"3.54.5"},"reference-count":20,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:00:00Z","timestamp":1779926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Cholera remains a substantial public health challenge in Africa, despite the availability of effective vaccines, treatment, and preventive measures. Systemic issues such as inadequate water, sanitation, and hygiene (WASH) infrastructure, weak disease surveillance, socio-economic disparities, and ongoing conflict and instability drive its persistence. This article provides the current situation of cholera in Africa, highlighting systemic barriers to control, including data deficiencies, limited diagnostic capacity, and infrastructural deficits. Crucially, we underline the importance of integrated strategies encompassing enhanced surveillance, targeted vaccination campaigns, WASH improvements, and addressing social determinants like poverty and displacement. Strengthening multisectoral and multidisciplinary collaborations and leveraging technological innovations are vital steps toward eliminating cholera in Africa. Achieving this goal requires sustained political commitment, increased resource mobilization, and context-specific solutions tailored to the diverse challenges faced by vulnerable communities.<\/jats:p>","DOI":"10.1371\/journal.pntd.0014325","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T17:24:41Z","timestamp":1779989081000},"page":"e0014325","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cholera in Africa: Current trends, challenges, and control towards elimination strategies"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4180-442X","authenticated-orcid":true,"given":"Claude Mambo","family":"Muvunyi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel Edwar","family":"Siddig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eman Taha Osman","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick Gad","family":"Iradukunda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Gashema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"de Dieu Harelimana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazyanga Lucy","family":"Mazaba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Kaseya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,5,28]]},"reference":[{"issue":"2","key":"pntd.0014325.ref001","first-page":"148","article-title":"Cholera resurgence in Africa: assessing progress, challenges, and public health response towards the 2030 global elimination target","volume":"32","author":"BO Amisu","year":"2024","journal-title":"Infez Med"},{"issue":"8946","key":"pntd.0014325.ref002","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0140-6736(95)90344-5","article-title":"Why treatment centres failed to prevent cholera deaths among Rwandan refugees in Goma, Zaire","volume":"345","author":"AK Siddique","year":"1995","journal-title":"Lancet"},{"issue":"6","key":"pntd.0014325.ref003","article-title":"Unmasking and tackling the underestimation of the cholera burden in Africa: A viewpoint","volume":"19","author":"OO Olu","year":"2025","journal-title":"PLoS Negl Trop Dis"},{"issue":"5","key":"pntd.0014325.ref004","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.3390\/microorganisms13051169","article-title":"Advances in wastewater-based epidemiology for pandemic surveillance: methodological frameworks and future perspectives","volume":"13","author":"W Zhu","year":"2025","journal-title":"Microorganisms"},{"key":"pntd.0014325.ref005","unstructured":"World Health organization. Multi-country outbreak of cholera, external situation report #27. 17 June 2025 [cited 23 May 2025]. 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