{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T18:28:02Z","timestamp":1786559282335,"version":"build-2736575974"},"reference-count":50,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Cholera remains a critical public health challenge in Dhaka, Bangladesh, influenced by complex environmental and demographic drivers. This study analyzed around 20 years of 2% surveillance data (2004\u20132024) from icddr,b (n\u2009=\u200937,361) to investigate long-term trends and climatic associations using distributed lag non-linear models (DLNMs). Climate data (temperature, rainfall, humidity) were obtained from NASA\u2019s Earth Data archives. Findings reveal a significant demographic shift, with adults (&gt;18 years) accounting for 65% of the 6,141 confirmed cholera cases. Seasonality was pronounced; 48% of cases occurred during the pre-monsoon period. While incidence peaked between 2004 and 2008, a recent resurgence was noted from 2019 to 2024. Environmental analysis showed a positive association between temperature and cholera risk, with relative risk (RR) rising from 0.75 at 20\u00b0C to 1.10 at 40\u00b0C. Precipitation emerged as a major driver, with risk peaking at 150 mm (RR\u2009=\u20091.5), high humidity (90%) also correlated with increased risk (RR\u2009=\u20091.10). The high burden among adults necessitates age-inclusive interventions, including targeted vaccination and WASH measures. Integrating climate data into early warning systems and expanding surveillance to informal settlements are vital for future outbreak prediction and control.<\/jats:p>","DOI":"10.1371\/journal.pntd.0014620","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T17:35:56Z","timestamp":1786556156000},"page":"e0014620","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two decades of cholera in Dhaka, Bangladesh: Epidemiology, seasonal patterns, and environmental risk, insights from 2004\u20132024"],"prefix":"10.1371","volume":"20","author":[{"given":"Mohammad Ashraful","family":"Amin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. 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