{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T18:32:05Z","timestamp":1788201125479,"version":"build-2803163510"},"update-to":[{"DOI":"10.1371\/journal.pntd.0014664","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000}}],"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"\n Background<\/jats:title>\n Soil-transmitted helminthiasis (STH) remains a major public health problem in many low- and middle-income countries (LMICs) despite widespread implementation of mass drug administration (MDA). Rapid reinfection after treatment highlights the limitations of MDA approaches and underscores the need for complementary interventions. Water, sanitation, hygiene, and health education (WASH) interventions are widely promoted as essential components of integrated STH control strategies. However, evidence on WASH impact and cost-effectiveness remains fragmented and is poorly synthesized. This scoping review aimed to systematically map and summarize the evidence on the impact and cost-effectiveness of WASH interventions for STH control and elimination.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Following Arksey and O\u2019Malley\u2019s framework and the Preferred Reporting Items for Systematic reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) guidelines, we conducted a scoping review of peer-reviewed and grey literature with no date restrictions. We searched PubMed and Google Scholar for papers that met our inclusion criteria. Studies assessing the impact and\/or cost-effectiveness of WASH interventions, alone or integrated with MDA, on STH outcomes were included.<\/jats:p>\n <\/jats:sec>\n \n Principal findings<\/jats:title>\n \n Sixteen studies, predominantly from LMICs, met the inclusion criteria, with Kenya contributing the largest number. Findings showed that combining WASH interventions with MDA led to greater reductions in reinfection with\n Ascaris lumbricoides<\/jats:italic>\n than MDA alone, particularly in school- and community-based programs. However, behavioural improvements alone were insufficient without supporting infrastructure, and their effects on other helminths were inconsistent. Notably, only one study conducted a formal cost-effectiveness analysis of WASH interventions, revealing a critical gap in economic evidence.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Integrating WASH interventions with MDA can enhance STH control outcomes, particularly for\n A. lumbricoides,<\/jats:italic>\n but the lack of robust economic evaluations limits informed policy and investment decisions. Future research should prioritize cost-effectiveness analyses and long-term assessments of integrated WASH strategies to support sustainable STH elimination efforts.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1371\/journal.pntd.0014664","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:39:16Z","timestamp":1787679556000},"page":"e0014664","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact and cost-effectiveness of water, sanitation, hygiene, and health education interventions in the control and elimination of soil-transmitted helminthiasis: A scoping review"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2647-1359","authenticated-orcid":true,"given":"Collins","family":"Okoyo","sequence":"first","affiliation":[{"name":"Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute","place":["Nairobi, Kenya"]},{"name":"Kenya Medical Research Institute","place":["Nairobi, Kenya"],"department":["Department of Epidemiology, Statistics and Informatics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Odhiambo","sequence":"additional","affiliation":[{"name":"Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geofrey","family":"Chepchieng","sequence":"additional","affiliation":[{"name":"Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kioko","sequence":"additional","affiliation":[{"name":"Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Britney","family":"Nyanchama","sequence":"additional","affiliation":[{"name":"Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Anjela","sequence":"additional","affiliation":[{"name":"Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Mwandawiro","sequence":"additional","affiliation":[{"name":"Eastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Minnery","sequence":"additional","affiliation":[{"name":"Deworm the World Initiative, Evidence Action","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"issue":"1","key":"pntd.0014664.ref001","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1186\/s12889-020-08485-z","article-title":"Soil-transmitted helminths and schistosomiasis among pre-school age children in a rural setting of Busia County, Western Kenya: a cross-sectional study of prevalence, and associated exposures","volume":"20","author":"J Masaku","year":"2020","journal-title":"BMC Public Health"},{"key":"pntd.0014664.ref002","doi-asserted-by":"crossref","first-page":"7680124","DOI":"10.1155\/2016\/7680124","article-title":"Current status of soil-transmitted helminths among school children in Kakamega County, Western Kenya","volume":"2016","author":"T Ngonjo","year":"2016","journal-title":"J Parasitol Res"},{"key":"pntd.0014664.ref003","doi-asserted-by":"crossref","DOI":"10.1186\/s13071-015-1187-5","article-title":"An economic evaluation of expanding hookworm control strategies to target the whole community","author":"HC Turner","year":"2015"},{"key":"pntd.0014664.ref004","article-title":"Schistosomiasis, soil transmitted helminthiasis, and malaria co-infections among women of reproductive age in rural communities of Kwale County, coastal Kenya","author":"T Jeza V","year":"2021"},{"key":"pntd.0014664.ref005","doi-asserted-by":"crossref","DOI":"10.1186\/s13071-019-3322-1","article-title":"Results of a national school-based deworming programme on soil-transmitted helminths infections and schistosomiasis in Kenya: 2012-2017","author":"C Mwandawiro","year":"2019"},{"key":"pntd.0014664.ref006","unstructured":"World Health Organization. Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021\u20132030; 2020. 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