{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T19:06:50Z","timestamp":1788894410298,"version":"build-2803163510"},"update-to":[{"DOI":"10.1371\/journal.pntd.0014697","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000}}],"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Dengue has historically been characterized as a childhood disease, but evidence of shifting age distribution is increasing. We analyzed 20 years (2005\u20132024) of national dengue surveillance data from Thailand comprising 1,639,442 cases to examine temporal trends in age-specific incidence, quantify age shift magnitude using the ratio of incidence rate ratios (RIRR), and decompose observed changes using Kitagawa decomposition. The proportion of cases among adults \u226525 years nearly doubled from 19.56% to 36.16%, while the children\u2019s proportion declined from 54.49% to 41.63%. RIRR for adults 25\u201344 years was 1.78 (95% CI 1.76-1.80), and for older adults \u226545 years was 2.19 (95% CI 2.15-2.24). Kitagawa decomposition attributed +178.7% of change to epidemiological factors and -78.7% to demographic shifts, supporting a declining force of infection rather than population aging as the primary driver. These findings necessitate expanding dengue prevention beyond school-based programs and enhancing clinical vigilance for adult dengue.<\/jats:p>","DOI":"10.1371\/journal.pntd.0014697","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T17:34:21Z","timestamp":1788197661000},"page":"e0014697","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Epidemiological shift in age distribution of dengue in Thailand, 2005\u20132024"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2734-0764","authenticated-orcid":true,"given":"Kittipong","family":"Sornlorm","sequence":"first","affiliation":[{"name":"Khon Kaen University","place":["Khon Kaen, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshan Kumar","family":"Mahato","sequence":"additional","affiliation":[{"name":"Khon Kaen University","place":["Khon Kaen, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarayu","family":"Muntaphan","sequence":"additional","affiliation":[{"name":"Khon Kaen Provincial Public Health Office","place":["Khon Kaen, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanit","family":"Hnuploy","sequence":"additional","affiliation":[{"name":"Suratthani Rajabhat University","place":["Surat Thani, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-9773-7611","authenticated-orcid":true,"given":"Rajitra","family":"Nawawonganun","sequence":"additional","affiliation":[{"name":"Khon Kaen University","place":["Khon Kaen, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"issue":"7446","key":"pntd.0014697.ref001","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1038\/nature12060","article-title":"The global distribution and burden of dengue","volume":"496","author":"S Bhatt","year":"2013","journal-title":"Nature"},{"key":"pntd.0014697.ref002","unstructured":"World Health Organization. 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