{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:38:25Z","timestamp":1792607905625,"version":"4.5.0"},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T00:00:00Z","timestamp":1792540800000},"content-version":"am","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hubei Key Research and Development Project","award":["2024BBB073"],"award-info":[{"award-number":["2024BBB073"]}]},{"name":"Sichuan Provincial Clinical Research Center for Imaging Medicine \u2013 Open Research Project","award":["YXYX2506"],"award-info":[{"award-number":["YXYX2506"]}]},{"name":"Sichuan Provincial Clinical Research Center for Imaging Medicine \u2013 Open Research Project","award":["YXYX2604"],"award-info":[{"award-number":["YXYX2604"]}]},{"name":"Wuhan Donghu University \u2013 High-Level Talent Start-up Funds","award":["DHRC2026053"],"award-info":[{"award-number":["DHRC2026053"]}]},{"name":"Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education \u2013 Open Project","award":["XN202402"],"award-info":[{"award-number":["XN202402"]}]},{"name":"Ganzhou Science and Technology Innovation Talent Project \u2013 Youth Talent Project","award":["2022CXRC9555"],"award-info":[{"award-number":["2022CXRC9555"]}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vector-borne diseases (VBDs) continue to pose a public health burden in China. However, changes in the reported incidence and mortality of VBDs during the COVID-19 period remain insufficiently characterized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed five major VBDs\u2014typhus, dengue, leishmaniasis, malaria, and epidemic encephalitis B (EEB)\u2014in China from 2004 to 2023. Province- and age-specific surveillance data for 2004\u20132020 were obtained from the Chinese Center for Disease Control and Prevention, whereas national aggregate data for 2021\u20132023 were obtained from the National Health Commission. Accordingly, spatial and age-specific analyses were restricted to 2004\u20132020, while national trend analyses were extended through 2023. Annual trends were evaluated using Joinpoint regression, monthly seasonal patterns were assessed using STL decomposition, monthly changes after January 2020 were evaluated using interrupted time-series analysis, and expected monthly trajectories for 2020\u20132023 were estimated using SARIMA models trained on pre-COVID data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From 2004 to 2020, incidence and mortality of VBDs declined significantly, especially for malaria, dengue, and EEB, and spatial hotspots were concentrated mainly in southern provinces. Compared with 2013\u20132019, overall incidence and mortality during 2020\u20132023 were 59.86% lower (95% CI: \u201360.36 to \u201359.36; P\u2009&lt;\u20090.001) and 83.72% lower (95% CI: \u201387.86 to \u201378.18; P\u2009&lt;\u20090.001), respectively. Malaria and EEB showed the largest reductions, whereas typhus and leishmaniasis changed less markedly. However, these declines should be interpreted cautiously because they may reflect a combination of COVID-19-era public health measures, pre-existing long-term trends, disease-specific control programs, and possible surveillance disruption.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>During the COVID-19 period in China, reported VBD incidence and mortality decreased substantially. However, it would be overly simplistic to attribute these changes entirely to COVID-19-related interventions, as other factors were also likely involved. These findings highlight the need for reliable surveillance and reporting during public health emergencies, together with forecasting tools that can be adapted to changing conditions, to support future vector-borne disease control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pntd.0014745","type":"journal-article","created":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:48:30Z","timestamp":1792604910000},"page":"e0014745","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal trends in reported vector-borne diseases in China before and after the onset of COVID-19 from 2004 to 2023"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5180-5405","authenticated-orcid":true,"given":"Zhiqun","family":"Lei","sequence":"first","affiliation":[{"name":"Institute of Biomedicine, Wuhan Donghu University","place":["Wuhan, Hubei, 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