{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:55:17Z","timestamp":1791568517911,"version":"4.3.4"},"reference-count":109,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T00:00:00Z","timestamp":1791504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004493","name":"International Atomic Energy Agency","doi-asserted-by":"publisher","award":["D42018"],"award-info":[{"award-number":["D42018"]}],"id":[{"id":"10.13039\/501100004493","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"<jats:p>Tsetse (Diptera: Glossinidae) are the exclusive cyclical vector of human and animal African trypanosomoses and continue to threaten health and agricultural productivity across sub-Saharan Africa. Area-wide integrated pest management (AW-IPM) strategies provide a coordinated framework for combining tools such as the sterile insect technique (SIT), insecticide-treated targets and cattle, and others. This review examines the success and challenges of AW-IPM in tsetse control and advances in population genetics, species distribution modeling, and landscape genetics that improve identification of candidate populations for optimized AW-IPM design. We introduce the Coordinated Research Project (CRP) \u201cTsetse Population Genetics,\u201d supported by the Joint FAO\/IAEA Centre, which aims to develop standardized tools and data to guide SIT within integrated control strategies. We identify key gaps in evidence for population isolation and reinvasion risk and propose an integrated, decision-ready framework. The framework combines updated species distribution models with scalable genomic tools to generate connectivity maps and, where feasible, source\u2013sink dynamics, to prioritize intervention sites and distinguish post-control reinvasion from true elimination.<\/jats:p>","DOI":"10.1371\/journal.pntd.0014752","type":"journal-article","created":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:30:04Z","timestamp":1791567004000},"page":"e0014752","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["From islands to landscapes: Integrating genomic and advanced eco-geographic tools in area-wide tsetse control"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8974-0301","authenticated-orcid":true,"given":"Norah","family":"Saarman","sequence":"first","affiliation":[{"name":"Utah State University","place":["Logan, Utah, United States of America"],"department":["Department of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantel Janet","family":"De Beer","sequence":"additional","affiliation":[{"name":"International Atomic Energy Agency","place":["Vienna, Austria"],"department":["Insect Pest Control Section, Joint FAO\/IAEA Centre of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Solano","sequence":"additional","affiliation":[{"name":"INTERTRYP, CIRAD, IRD, and University of Montpellier","place":["Montpellier, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Barreaux","sequence":"additional","affiliation":[{"name":"INTERTRYP, CIRAD, IRD, and University of Montpellier","place":["Montpellier, France"]},{"name":"INTERTRYP, CIRAD","place":["Nairobi, Kenya"]},{"name":"International Centre of Insect Physiology and Ecology (ICIPE)","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Gimonneau","sequence":"additional","affiliation":[{"name":"INTERTRYP, CIRAD, IRD, and University of Montpellier","place":["Montpellier, France"]},{"name":"INTERTRYP, CIRAD","place":["Nairobi, Kenya"]},{"name":"International Centre of Insect Physiology and Ecology (ICIPE)","place":["Nairobi, Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Ravel","sequence":"additional","affiliation":[{"name":"INTERTRYP, CIRAD, IRD, and University of Montpellier","place":["Montpellier, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Opiro","sequence":"additional","affiliation":[{"name":"Gulu University","place":["Gulu, Uganda"],"department":["Department of Biology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Amatulli","sequence":"additional","affiliation":[{"name":"Spatial Ecology","place":["Penn, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliano","family":"Cecchi","sequence":"additional","affiliation":[{"name":"Food and Agriculture Organization of the United Nations (FAO)","place":["Rome, Italy"],"department":["Animal Production and Health Division"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serap","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Yale School of Public Health","place":["New Haven, Connecticut, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Weiss","sequence":"additional","affiliation":[{"name":"Yale School of Public Health","place":["New Haven, Connecticut, United States of America"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kostas","family":"Bourtzis","sequence":"additional","affiliation":[{"name":"International Atomic Energy Agency","place":["Vienna, Austria"],"department":["Insect Pest Control Section, Joint FAO\/IAEA Centre of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7540-4462","authenticated-orcid":true,"given":"Adly M. 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