{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T18:38:51Z","timestamp":1792780731426,"version":"4.5.0"},"update-to":[{"DOI":"10.1371\/journal.pntd.0014806","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000}}],"reference-count":17,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosntds.org"],"crossmark-restriction":false},"short-container-title":["PLoS Negl Trop Dis"],"abstract":"\n Background<\/jats:title>\n Delayed diagnosis in leprosy reflects both how people interpret symptoms and seek care, and how effectively health systems recognize and manage the disease. Qualitative evidence from Tanzania remains limited on how the interaction between patients and health care workers affect provision of care to people affected by leprosy in a timely manner. The main aim of this study was to explore health-seeking behaviors and systemic challenges affecting access to biomedical care among people affected by leprosy in selected Tanzanian communities.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Ethics Statement: Ethical approval for the study was obtained from the Medical Research Coordinating Committee (MRCC) through the National Health Research Ethics Committee (NatHREC) with reference number NIMR\/HQ\/R.8a\/Vol.IX\/4587. Written informed consent was obtained from all participants before data collection. Identifying information was removed from transcripts, data were anonymized before analysis, and audio files and transcripts were stored on password-protected computers accessible only to the data manager and the principal investigator. Data will be retained for up to 10 years per NIMR policy. An anonymized coding framework and de-identified extracts are available upon reasonable request. Given the sensitive nature of gender-based violence disclosures, referral procedures were established to ensure that participants requiring additional support could be linked to appropriate services This qualitative study was conducted in Tanga and Morogoro regions, Tanzania. Semi-structured interviews and focus group discussions were held with people affected by leprosy, community members, District Tuberculosis and Leprosy Coordinators, Community Health Workers, and Prevention of Disability officers. Data were audio-recorded, transcribed, translated into English, and analyzed thematically.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Our findings revealed various factors which contributed to delays in seeking for biomedical care among people affected with leprosy. First, early symptoms were often normalized or attributed to witchcraft and curses, prompting initial care from traditional healers. Second, stigma, fear of rejection, and advice from relatives and community members delayed disclosure and transition to biomedical care. Third, health-system barriers including misdiagnosis, limited provider familiarity with leprosy, referral delays, medicine shortages, and inadequate support for disability management delayed confirmation of diagnosis and initiation of appropriate treatment.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Health-seeking behaviors among people affected by leprosy were shaped by stigma, social influence, and health-system barriers that delayed or limited access to biomedical care. Evidence-based interventions, including culturally sensitive education, stigma reduction, and strengthening of frontline biomedical services, can help overcome these barriers. Policy efforts should prioritize biomedical care alongside community-based awareness to reduce stigma and promote timely care-seeking.<\/jats:p>\n <\/jats:sec>","DOI":"10.1371\/journal.pntd.0014806","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:47:16Z","timestamp":1792086436000},"page":"e0014806","update-policy":"https:\/\/doi.org\/10.1371\/journal.pntd.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Barriers to biomedical care: Qualitative insights into health-seeking behaviors and systemic challenges among people affected by leprosy in Tanzanian communities"],"prefix":"10.1371","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-5034-5618","authenticated-orcid":true,"given":"Sylivester Asimwe","family":"Muhigi","sequence":"first","affiliation":[{"name":"National Institute for Medical Research, Muhimbili Research Centre","place":["Dar es Salaam, Tanzania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kijakazi","family":"Mashoto","sequence":"additional","affiliation":[{"name":"National Institute for Medical Research, Headquarters","place":["Dodoma, Tanzania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercy","family":"Chiduo","sequence":"additional","affiliation":[{"name":"National Institute for Medical Research, Dodoma Medical Research Centre","place":["Dodoma, Tanzania"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2026,10,15]]},"reference":[{"key":"pntd.0014806.ref001","volume-title":"Leprosy [Internet]","author":"World Health Organization (WHO)","year":"2024"},{"key":"pntd.0014806.ref002","unstructured":"WHO. Leprosy. WHO. https:\/\/www.afro.who.int\/health-topics\/leprosy 2024. 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Towards zero leprosy global leprosy (Hansen\u2019s disease) strategy 2021-2030. 8. World Health Organization. 2021."}],"updated-by":[{"DOI":"10.1371\/journal.pntd.0014806","type":"new_version","label":"New version","source":"publisher","updated":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000}}],"container-title":["PLOS Neglected Tropical Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0014806","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T17:48:55Z","timestamp":1792777735000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pntd.0014806"}},"subtitle":[],"editor":[{"given":"Anil","family":"Fastenau","sequence":"first","affiliation":[{"name":"Marie Adelaide Leprosy Center","place":["PAKISTAN"]}],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2026,10,15]]},"references-count":17,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2026,10,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pntd.0014806","relation":{},"ISSN":["1935-2735"],"issn-type":[{"value":"1935-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,15]]}}}