{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:59:46Z","timestamp":1791305986067,"version":"4.3.1"},"reference-count":37,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2007,9,5]],"date-time":"2007-09-05T00:00:00Z","timestamp":1188950400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0000822","type":"journal-article","created":{"date-parts":[[2007,9,4]],"date-time":"2007-09-04T23:42:43Z","timestamp":1188949363000},"page":"e822","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":37,"title":["An Outbreak of Severe Infections with Community-Acquired MRSA Carrying the Panton-Valentine Leukocidin Following Vaccination"],"prefix":"10.1371","volume":"2","author":[{"given":"Tang","family":"Chi Thuong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Dac Tho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ngo","family":"Thi Hoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Thi","family":"Minh Phuong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Van Tuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"To","family":"Song Diep","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodi","family":"Lindsay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"The Dung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bach","family":"Van Cam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Quoc\u00a0Thinh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Thanh Hai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Dieu Linh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Thi","family":"Kim Tien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Van","family":"Vinh Chau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Cockfield","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Truong Giang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phan","family":"Van Nghiem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Hoang Son","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huynh","family":"Tan Son","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Van Phung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Counahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adwoa","family":"Bentsi-Enchill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Simmerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen","family":"Tran Chinh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tran","family":"Tinh Hien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Farrar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance","family":"Schultsz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2007,9,5]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1128\/CMR.10.3.505","article-title":"Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks.","volume":"10","author":"J Kluytmans","year":"1997","journal-title":"Clin Microbiol Rev"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3201\/eid1001.030144","article-title":"Panton-valentine leukocidin and staphyloccoccal skin infections in schoolchildren.","volume":"10","author":"K Boubaker","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1056\/NEJMoa043252","article-title":"Methicillin-resistant Staphylococcus aureus disease in three communities.","volume":"352","author":"SK Fridkin","year":"2005","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0140-6736(02)07877-7","article-title":"Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients.","volume":"359","author":"Y Gillet","year":"2002","journal-title":"Lancet"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1056\/NEJMoa042683","article-title":"Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles.","volume":"352","author":"LG Miller","year":"2005","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1056\/NEJMoa055356","article-title":"Methicillin-resistant S. aureus infections among patients in the emergency department.","volume":"355","author":"GJ Moran","year":"2006","journal-title":"N Engl J Med"},{"key":"ref7","first-page":"973","article-title":"Community-acquired methicillin-resistant Staphylococcus aureus, Uruguay.","volume":"11","author":"XX Ma","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"978","DOI":"10.3201\/eid0908.030089","article-title":"Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence.","volume":"9","author":"F Vandenesch","year":"2003","journal-title":"Emerg Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"808","DOI":"10.3201\/eid1106.040885","article-title":"Community-associated methicillin-resistant Staphylococcus aureus in hospital nursery and maternity units.","volume":"11","author":"S Bratu","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2994","DOI":"10.1128\/JCM.00846-06","article-title":"Multiple cases of familial transmission of community-acquired methicillin-resistant Staphylococcus aureus.","volume":"44","author":"XW Huijsdens","year":"2006","journal-title":"J Clin Microbiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1056\/NEJMoa042859","article-title":"A clone of methicillin-resistant Staphylococcus aureus among professional football players.","volume":"352","author":"SV Kazakova","year":"2005","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1086\/432072","article-title":"Population dynamics of nasal strains of methicillin-resistant Staphylococcus aureus\u2013and their relation to community-associated disease activity.","volume":"192","author":"ES Pan","year":"2005","journal-title":"J Infect Dis"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jhin.2005.11.016","article-title":"Control of a cluster of community-associated, methicillin-resistant Staphylococcus aureus in neonatology.","volume":"63","author":"H Sax","year":"2006","journal-title":"J Hosp Infect"},{"key":"ref14","year":"2005"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1128\/JCM.33.3.551-555.1995","article-title":"Pulsed-field gel electrophoresis as a replacement for bacteriophage typing of Staphylococcus aureus.","volume":"33","author":"TL Bannerman","year":"1995","journal-title":"J Clin Microbiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1128\/JCM.33.9.2233-2239.1995","article-title":"Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.","volume":"33","author":"FC Tenover","year":"1995","journal-title":"J Clin Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1128\/JCM.38.3.1008-1015.2000","article-title":"Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus.","volume":"38","author":"MC Enright","year":"2000","journal-title":"J Clin Microbiol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1128\/JB.186.5.1518-1530.2004","article-title":"eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data.","volume":"186","author":"EJ Feil","year":"2004","journal-title":"J Bacteriol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1128\/AAC.50.3.1001-1012.2006","article-title":"Staphylococcal cassette chromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus strains isolated in 11 Asian countries: a proposal for a new nomenclature for SCCmec elements.","volume":"50","author":"P Chongtrakool","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1128\/IAI.70.2.631-641.2002","article-title":"Relationships between Staphylococcus aureus genetic background, virulence factors, agr groups (alleles), and human disease.","volume":"70","author":"S Jarraud","year":"2002","journal-title":"Infect Immun"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"7504","DOI":"10.1128\/AEM.71.11.7504-7514.2005","article-title":"Design, validation, and application of a seven-strain Staphylococcus aureus PCR product microarray for comparative genomics.","volume":"71","author":"AA Witney","year":"2005","journal-title":"Appl Environ Microbiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1128\/JCM.42.5.2080-2084.2004","article-title":"Widespread skin and soft-tissue infections due to two methicillin-resistant Staphylococcus aureus strains harboring the genes for Panton-Valentine leucocidin.","volume":"42","author":"BA Diep","year":"2004","journal-title":"J Clin Microbiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s150100050024","article-title":"Streptococcal toxic shock syndrome in two patients infected by a colonized surgeon.","volume":"27","author":"J Rutishauser","year":"1999","journal-title":"Infection"},{"key":"ref24","first-page":"1","article-title":"Surveillance for safety after immunization: Vaccine Adverse Event Reporting System (VAERS) \u2013United States, 1991\u20132001.","volume":"52","author":"W Zhou","year":"2003","journal-title":"MMWR Surveill Summ"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/00006454-199305000-00003","article-title":"Outbreak of pyogenic abscesses after diphtheria and tetanus toxoids and pertussis vaccination.","volume":"12","author":"PA Simon","year":"1993","journal-title":"Pediatr Infect Dis J"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"341","DOI":"10.3201\/eid1102.040782","article-title":"Community associated methicillin-resistant Staphylococcus aureus, Singapore.","volume":"11","author":"LY Hsu","year":"2005","journal-title":"Emerg Infect Dis"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.annemergmed.2005.05.023","article-title":"Fatal community-associated methicillin-resistant Staphylococcus aureus pneumonia in an immunocompetent young adult.","volume":"46","author":"BW Frazee","year":"2005","journal-title":"Ann Emerg Med"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1542\/peds.2004-2300","article-title":"Severe Staphylococcal sepsis in adolescents in the era of community-acquired methicillin-resistant Staphylococcus aureus.","volume":"115","author":"BE Gonzalez","year":"2005","journal-title":"Pediatrics"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1086\/502526","article-title":"Dispersal of Staphylococcus aureus into the air associated with a rhinovirus infection.","volume":"26","author":"S Bassetti","year":"2005","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref30","article-title":"WHO Best infection control practices for skinpiercing, intradermal subcutateous and intramuscular needle injections"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.surg.2005.06.045","article-title":"Molecular epidemiology of microbial contamination in the operating room environment: Is there a risk for infection?","volume":"138","author":"CE Edmiston Jr","year":"2005","journal-title":"Surgery"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1086\/313461","article-title":"Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia.","volume":"29","author":"G Lina","year":"1999","journal-title":"Clin Infect Dis"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1128\/CMR.13.1.16-34.2000","article-title":"Exotoxins of Staphylococcus aureus.","volume":"13","author":"MM Dinges","year":"2000","journal-title":"Clin Microbiol Rev"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"4719","DOI":"10.1128\/JCM.43.9.4719-4730.2005","article-title":"Successful multiresistant community-associated methicillin-resistant Staphylococcus aureus lineage from Taipei, Taiwan, that carries either the novel Staphylococcal chromosome cassette mec (SCCmec) type VT or SCCmec type IV.","volume":"43","author":"S Boyle-Vavra","year":"2005","journal-title":"J Clin Microbiol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1128\/JB.188.2.669-676.2006","article-title":"Microarrays reveal that each of the ten dominant lineages of Staphylococcus aureus has a unique combination of surface-associated and regulatory genes.","volume":"188","author":"JA Lindsay","year":"2006","journal-title":"J Bacteriol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/S0140-6736(02)08713-5","article-title":"Genome and virulence determinants of high virulence community-acquired MRSA.","volume":"359","author":"T Baba","year":"2002","journal-title":"Lancet"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0140-6736(06)68231-7","article-title":"Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus.","volume":"367","author":"BA Diep","year":"2006","journal-title":"Lancet"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0000822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,26]],"date-time":"2020-04-26T08:55:30Z","timestamp":1587891330000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0000822"}},"subtitle":[],"editor":[{"given":"Matthew","family":"Baylis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2007,9,5]]},"references-count":37,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2007,9,5]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0000822","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,9,5]]}}}