{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:15:13Z","timestamp":1790252113972,"version":"4.1.0"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2008,4,23]],"date-time":"2008-04-23T00:00:00Z","timestamp":1208908800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0001993","type":"journal-article","created":{"date-parts":[[2008,4,22]],"date-time":"2008-04-22T18:34:56Z","timestamp":1208889296000},"page":"e1993","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":90,"title":["Intradermally Administered Yellow Fever Vaccine at Reduced Dose Induces a Protective Immune Response: A Randomized Controlled Non-Inferiority Trial"],"prefix":"10.1371","volume":"3","clinical-trial-number":[{"clinical-trial-number":"isrctn46326316","registry":"10.18810\/isrctn"}],"author":[{"given":"Anna H.","family":"Roukens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann C.","family":"Vossen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Bredenbeek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaap T.","family":"van Dissel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo G.","family":"Visser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2008,4,23]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1001\/jama.1996.03540140045025","article-title":"Yellow fever: a decade of reemergence.","volume":"276","author":"SE Robertson","year":"1996","journal-title":"JAMA"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1473-3099(01)00016-0","article-title":"Yellow fever: an update.","volume":"1","author":"TP Monath","year":"2001","journal-title":"Lancet Infect Dis"},{"key":"ref3","first-page":"317","article-title":"Weekly epidemiological record. Yellow fever situation in Africa and South America.","volume":"81","year":"2005"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1126\/science.316.5828.1109","article-title":"Infectious disease. Resurgence of yellow fever in Africa prompts a counterattack.","volume":"316","author":"L Roberts","year":"2007","journal-title":"Science"},{"key":"ref5","first-page":"815","article-title":"Yellow Fever.","author":"TP Monath","year":"1999"},{"key":"ref6","first-page":"219","article-title":"Stability of yellow fever vaccine.","volume":"87","author":"TP Monath","year":"1996","journal-title":"Dev Biol Stand"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2286","DOI":"10.1056\/NEJMoa043555","article-title":"Serum antibody responses after intradermal vaccination against influenza.","volume":"351","author":"RB Belshe","year":"2004","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1056\/NEJMoa043540","article-title":"Dose sparing with intradermal injection of influenza vaccine.","volume":"351","author":"RT Kenney","year":"2004","journal-title":"N Engl J Med"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1001\/jama.1985.03360220069031","article-title":"Clinical evaluation of low-dose intradermally administered hepatitis B virus vaccine. A cost reduction strategy.","volume":"254","author":"RR Redfield","year":"1985","journal-title":"JAMA"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0140-6736(83)90288-X","article-title":"An economical regimen of human diploid cell strain anti-rabies vaccine for post exposure prophylaxis.","volume":"2","author":"MJ Warrell","year":"1983","journal-title":"Lancet"},{"key":"ref11","first-page":"113","article-title":"Field studies on the immune response to 17D yellow fever virus. Relation to virus substrain, dose and route of inoculation.","volume":"38","author":"JP Fox","year":"1943","journal-title":"The American Journal of Hygiene"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1080\/00034983.1953.11685585","article-title":"Vaccination by scarification with 17D yellow fever vaccine prepared at Yaba, Lagos, Nigeria.","volume":"47","author":"SA Cannon","year":"1953","journal-title":"Ann Trop Med Parasitol"},{"key":"ref13","first-page":"140","article-title":"A preliminary evaluation of the immunizing power of chick-embryo 17 D yellow fever vaccine inoculated by scarification.","volume":"55","author":"GW Dick","year":"1952","journal-title":"Am J Hyg"},{"key":"ref14"},{"key":"ref15","first-page":"113","article-title":"A simple micro-culture method for the study of group B arboviruses.","volume":"40","author":"AT De Madrid","year":"1969","journal-title":"Bulletin of the World Health Organization"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1128\/AEM.25.4.539-544.1973","article-title":"Yellow fever vaccine: direct challenge of monkeys given graded doses of 17D vaccine.","volume":"25","author":"RA Mason","year":"1873","journal-title":"Appl Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.1128\/JCM.40.10.3666-3670.2002","article-title":"Rapid and sensitive routine detection of all members of the genus enterovirus in different clinical specimens by real-time PCR.","volume":"40","author":"M Nijhuis","year":"2002","journal-title":"J Clin Microbiol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1128\/JCM.40.7.2323-2330.2002","article-title":"Rapid detection and quantification of RNA of Ebola and Marburg viruses, Lassa virus, Crimean-Congo hemorrhagic fever virus, Rift Valley fever virus, dengue virus, and yellow fever virus by real-time reverse transcription-PCR.","volume":"40","author":"C Drosten","year":"2002","journal-title":"J Clin Microbiol"},{"key":"ref19","article-title":"Statistical methods in medical research. 4 ed","author":"P Armitage","year":"2002"},{"key":"ref20","year":"1998"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1586\/14760584.4.4.553","article-title":"Yellow Fever Vaccine.","volume":"4","author":"TP Monath","year":"2005","journal-title":"Exp rev vaccine"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"106","DOI":"10.4161\/hv.1.3.1797","article-title":"Cutaneous delivery of a live, attenuated chimeric flavivirus vaccine against Japanese encephalitis (ChimeriVax)-JE) in non-human primates.","volume":"1","author":"CH Dean","year":"2005","journal-title":"Human Vaccin"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/(SICI)1096-9071(199810)56:2<159::AID-JMV10>3.0.CO;2-B","article-title":"Development of viremia and humoral and cellular parameters of immune activation after vaccination with yellow fever virus strain 17D: a model of human flavivirus infection.","volume":"56","author":"B Reinhardt","year":"1998","journal-title":"J Med Virol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1084\/jem.20051352","article-title":"Live attenuated yellow fever 17D infects human DCs and allows for presentation of endogenous and recombinant T cell epitopes.","volume":"202","author":"G Barba-Spaeth","year":"2005","journal-title":"J Exp Med"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1099\/vir.0.82272-0","article-title":"Restricted replication and lysosomal trafficking of yellow fever 17D vaccine virus in human dendritic cells.","volume":"88","author":"DR Palmer","year":"2007","journal-title":"J Gen Virol"},{"key":"ref26","first-page":"153","volume":"82","year":"2007"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0001993","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,4]],"date-time":"2020-05-04T13:29:02Z","timestamp":1588598942000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0001993"}},"subtitle":[],"editor":[{"given":"Lorenz","family":"von Seidlein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2008,4,23]]},"references-count":26,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2008,4,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0001993","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,23]]}}}