{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:26:25Z","timestamp":1791307585688,"version":"4.3.1"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2009,8,10]],"date-time":"2009-08-10T00:00:00Z","timestamp":1249862400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0006572","type":"journal-article","created":{"date-parts":[[2009,8,7]],"date-time":"2009-08-07T17:57:51Z","timestamp":1249667871000},"page":"e6572","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":68,"title":["The Association between Intrauterine Inflammation and Spontaneous Vaginal Delivery at Term: A Cross-Sectional Study"],"prefix":"10.1371","volume":"4","author":[{"given":"Michiel L.","family":"Houben","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter G. J.","family":"Nikkels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grada M.","family":"van Bleek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard H. A.","family":"Visser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maroeska M.","family":"Rovers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilda","family":"Kessel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter J.","family":"de Waal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leontine","family":"Schuijff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annemiek","family":"Evers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan L. L.","family":"Kimpen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Bont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2009,8,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1056\/NEJMra061360","article-title":"Parturition.","volume":"356","author":"R Smith","year":"2007","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1080\/jmf.13.1.32.38","article-title":"Differences in the fetal interleukin-6 response to microbial invasion of the amniotic cavity between term and preterm gestation.","volume":"13","author":"BH Yoon","year":"2003","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref3","first-page":"383","article-title":"The prevalence and distribution of acute placental inflammation in uncomplicated term pregnancies.","volume":"73","author":"CM Salafia","year":"1989","journal-title":"Obstet Gynecol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1159\/000242940","article-title":"Initiation of labour.","volume":"55","author":"GC Liggins","year":"1989","journal-title":"Biol Neonate"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/S0002-9378(99)70400-X","article-title":"Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition.","volume":"181","author":"JA Keelan","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.siny.2006.05.001","article-title":"Inflammation in preterm and term labour and delivery.","volume":"11","author":"R Romero","year":"2006","journal-title":"Semin Fetal Neonatal Med"},{"key":"ref7","first-page":"543","article-title":"Microbial invasion of the amniotic cavity during term labor. Prevalence and clinical significance.","volume":"38","author":"R Romero","year":"1993","journal-title":"J Reprod Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1097\/GRF.0b013e31811ebef6","article-title":"The fetal inflammatory response syndrome.","volume":"50","author":"F Gotsch","year":"2007","journal-title":"Clin Obstet Gynecol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/j.ajog.2006.06.072","article-title":"Preterm labor is induced by intraamniotic infusions of interleukin-1beta and tumor necrosis factor-alpha but not by interleukin-6 or interleukin-8 in a nonhuman primate model.","volume":"195","author":"DW Sadowsky","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1177\/1933719107310992","article-title":"Pretreatment with toll-like receptor 4 antagonist inhibits lipopolysaccharide-induced preterm uterine contractility, cytokines, and prostaglandins in rhesus monkeys.","volume":"15","author":"KM Waldorf","year":"2008","journal-title":"Reprod Sci"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/0002-9378(93)90388-Y","article-title":"Transforming growth factor-beta 2 prevents preterm delivery induced by interleukin-1 alpha and tumor necrosis factor-alpha in the rabbit.","volume":"168","author":"K Bry","year":"1993","journal-title":"Am J Obstet Gynecol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/0002-9378(91)90450-6","article-title":"Systemic administration of interleukin-1 induces preterm parturition in mice.","volume":"165","author":"R Romero","year":"1991","journal-title":"Am J Obstet Gynecol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.ajog.2008.06.040","article-title":"The frequency of microbial invasion of the amniotic cavity and histologic chorioamnionitis in women at term with intact membranes in the presence or absence of labor.","volume":"199","author":"HS Seong","year":"2008","journal-title":"Am J Obstet Gynecol"},{"key":"ref14","first-page":"129","article-title":"Infection and labor. VII. Microbial invasion of the amniotic cavity in spontaneous rupture of membranes at term.","volume":"166","author":"R Romero","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"293","DOI":"10.2350\/06-01-0015.1","article-title":"Hypercoiling of the umbilical cord and placental maturation defect: associated pathology?","volume":"10","author":"MW de Laat","year":"2007","journal-title":"Pediatr Dev Pathol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s10024-003-7070-y","article-title":"Amniotic infection syndrome: nosology and reproducibility of placental reaction patterns.","volume":"6","author":"RW Redline","year":"2003","journal-title":"Pediatr Dev Pathol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1046\/j.1471-0528.2003.00023.x","article-title":"Mechanisms of labour\u2013biochemical aspects.","volume":"110","author":"BA Lopez","year":"2003","journal-title":"BJOG"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1046\/j.1471-0528.2003.00062.x","article-title":"Role of cytokines and other inflammatory mediators.","volume":"110","author":"M Winkler","year":"2003","journal-title":"BJOG"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/00003081-200609000-00015","article-title":"Cervical ripening: biochemical, molecular, and clinical considerations.","volume":"49","author":"H Maul","year":"2006","journal-title":"Clin Obstet Gynecol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1530\/rep.1.00709","article-title":"Induction of labour at the start of the new millennium.","volume":"131","author":"IZ Mackenzie","year":"2006","journal-title":"Reproduction"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1038\/nm0595-460","article-title":"A placental clock controlling the length of human pregnancy.","volume":"1","author":"M McLean","year":"1995","journal-title":"Nat Med"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1097\/01.qco.0000224819.42729.2e","article-title":"Antenatal infection and inflammation: what's new?","volume":"19","author":"NC Maxwell","year":"2006","journal-title":"Curr Opin Infect Dis"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"e3056","DOI":"10.1371\/journal.pone.0003056","article-title":"Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture-based investigation.","volume":"3","author":"DB DiGiulio","year":"2008","journal-title":"PLoS ONE"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1177\/1933719108325508","article-title":"Ureaplasma parvum or Mycoplasma hominis as sole pathogens cause chorioamnionitis, preterm delivery, and fetal pneumonia in rhesus macaques.","volume":"16","author":"MJ Novy","year":"2009","journal-title":"Reprod Sci"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1055\/s-2004-831884","article-title":"Identification and sequencing of bacterial rDNAs in culture-negative amniotic fluid from women in premature labor.","volume":"21","author":"C Gardella","year":"2004","journal-title":"Am J Perinatol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1128\/JCM.01206-08","article-title":"Uncultivated bacteria as etiologic agents of intra-amniotic inflammation leading to preterm birth.","volume":"47","author":"YW Han","year":"2009","journal-title":"J Clin Microbiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1080\/14767050701752601","article-title":"Expression of cytokines and chemokines in cervical and amniotic fluid: relationship to histological chorioamnionitis.","volume":"20","author":"RM Holst","year":"2007","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.humpath.2007.05.025","article-title":"Villitis of unknown etiology: noninfectious chronic villitis in the placenta.","volume":"38","author":"RW Redline","year":"2007","journal-title":"Hum Pathol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ejogrb.2007.06.018","article-title":"Chronic villitis of unknown etiology.","volume":"136","author":"G Boog","year":"2008","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.ajog.2004.06.062","article-title":"Placental villitis of unknown origin: epidemiologic associations.","volume":"192","author":"DM Becroft","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"4978","DOI":"10.1073\/pnas.0401124101","article-title":"Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition.","volume":"101","author":"JC Condon","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref32","first-page":"1080","article-title":"Amniotic fluid infection, cytokines, and adverse outcome among infants at 34 weeks' gestation or less.","volume":"98","author":"J Hitti","year":"2001","journal-title":"Obstet Gynecol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1001\/jama.292.4.462","article-title":"Diagnosis of intra-amniotic infection by proteomic profiling and identification of novel biomarkers.","volume":"292","author":"MG Gravett","year":"2004","journal-title":"JAMA"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/S0140-6736(03)14542-4","article-title":"Association between antenatal cytokine production and the development of atopy and asthma at age 6 years.","volume":"362","author":"C Macaubas","year":"2003","journal-title":"Lancet"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1111\/j.1471-0528.2007.01328.x","article-title":"Variation in rates of postterm birth in Europe: reality or artefact?","volume":"114","author":"J Zeitlin","year":"2007","journal-title":"BJOG"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/S0140-6736(07)61379-8","article-title":"Poor airway function in early infancy and lung function by age 22 years: a non-selective longitudinal cohort study.","volume":"370","author":"DA Stern","year":"2007","journal-title":"Lancet"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1067\/mob.2001.13321","article-title":"Chorioamnionitis and inflammation of the fetal lung.","volume":"185","author":"B Schmidt","year":"2001","journal-title":"Am J Obstet Gynecol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1164\/rccm.200512-1978OC","article-title":"Maternal complications and procedures in pregnancy and at birth and wheezing phenotypes in children.","volume":"175","author":"F Rusconi","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1056\/NEJM198810273191702","article-title":"Diminished lung function as a predisposing factor for wheezing respiratory illness in infants.","volume":"319","author":"FD Martinez","year":"1988","journal-title":"N Engl J Med"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0006572","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T15:41:53Z","timestamp":1710517313000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0006572"}},"subtitle":[],"editor":[{"given":"Linda","family":"Wright","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2009,8,10]]},"references-count":39,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2009,8,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0006572","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,8,10]]}}}