{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T05:57:13Z","timestamp":1760853433268},"reference-count":70,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2009,10,13]],"date-time":"2009-10-13T00:00:00Z","timestamp":1255392000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0007376","type":"journal-article","created":{"date-parts":[[2009,10,14]],"date-time":"2009-10-14T17:41:07Z","timestamp":1255542067000},"page":"e7376","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":14,"title":["Inhibition of RNA Recruitment and Replication of an RNA Virus by Acridine Derivatives with Known Anti-Prion Activities"],"prefix":"10.1371","volume":"4","author":[{"given":"Zsuzsanna","family":"Sasvari","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Bach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Blondel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter D.","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2009,10,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jhep.2008.10.011","article-title":"Directly acting antivirals for the treatment of patients with hepatitis C infection: a clinical development update addressing key future challenges.","volume":"50","author":"A Thompson","year":"2009","journal-title":"J Hepatol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.antiviral.2008.01.004","article-title":"Molecular strategies to inhibit the replication of RNA viruses.","volume":"78","author":"P Leyssen","year":"2008","journal-title":"Antiviral Res"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/rmv.483","article-title":"Mechanisms of action of ribavirin against distinct viruses.","volume":"16","author":"JD Graci","year":"2006","journal-title":"Rev Med Virol"},{"key":"ref4","first-page":"738","article-title":"R-1626, a specific oral NS5B polymerase inhibitor of hepatitis C virus.","volume":"11","author":"P Toniutto","year":"2008","journal-title":"IDrugs"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.ijantimicag.2008.07.013","article-title":"Pentoxifylline inhibits replication of Japanese encephalitis virus: a comparative study with ribavirin.","volume":"33","author":"L Sebastian","year":"2009","journal-title":"Int J Antimicrob Agents"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/j.1872-034X.2008.00352.x","article-title":"Griseofulvin, an oral antifungal agent, suppresses hepatitis C virus replication in vitro.","volume":"38","author":"H Jin","year":"2008","journal-title":"Hepatol Res"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1128\/AAC.01056-07","article-title":"Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues.","volume":"52","author":"JD Graci","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"ref8","first-page":"614","article-title":"Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections.","volume":"8","author":"PL Beaulieu","year":"2007","journal-title":"Curr Opin Investig Drugs"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.2174\/156802607781212211","article-title":"Recent progress in the development of inhibitors of the hepatitis C virus RNA-dependent RNA polymerase.","volume":"7","author":"U Koch","year":"2007","journal-title":"Curr Top Med Chem"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0079-6603(04)78005-8","article-title":"Advances in the molecular biology of tombusviruses: gene expression, genome replication, and recombination.","volume":"78","author":"KA White","year":"2004","journal-title":"Prog Nucleic Acid Res Mol Biol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.1128\/JVI.79.8.4848-4858.2005","article-title":"The p92 polymerase coding region contains an internal RNA element required at an early step in Tombusvirus genome replication.","volume":"79","author":"S Monkewich","year":"2005","journal-title":"J Virol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.virol.2005.04.025","article-title":"The role of the p33:p33\/p92 interaction domain in RNA replication and intracellular localization of p33 and p92 proteins of Cucumber necrosis tombusvirus.","volume":"338","author":"T Panavas","year":"2005","journal-title":"Virology"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"4859","DOI":"10.1128\/JVI.79.8.4859-4869.2005","article-title":"Specific Binding of Tombusvirus Replication Protein p33 to an Internal Replication Element in the Viral RNA Is Essential for Replication.","volume":"79","author":"J Pogany","year":"2005","journal-title":"J Virol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"10608","DOI":"10.1128\/JVI.79.16.10608-10618.2005","article-title":"Role of an internal and two 3\u2032-terminal RNA elements in assembly of tombusvirus replicase.","volume":"79","author":"Z Panaviene","year":"2005","journal-title":"J Virol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"5845","DOI":"10.1128\/JVI.72.7.5845-5851.1998","article-title":"Uncoupled expression of p33 and p92 permits amplification of tomato bushy stunt virus RNAs.","volume":"72","author":"SK Oster","year":"1998","journal-title":"J Virol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0042-6822(03)00436-7","article-title":"Yeast as a model host to study replication and recombination of defective interfering RNA of Tomato bushy stunt virus.","volume":"314","author":"T Panavas","year":"2003","journal-title":"Virology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0042-6822(02)00132-0","article-title":"The overlapping RNA-binding domains of p33 and p92 replicase proteins are essential for tombusvirus replication.","volume":"308","author":"Z Panaviene","year":"2003","journal-title":"Virology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.virol.2005.09.038","article-title":"Kinetics and functional studies on interaction between the replicase proteins of Tomato Bushy Stunt Virus: requirement of p33:p92 interaction for replicase assembly.","volume":"345","author":"KS Rajendran","year":"2006","journal-title":"Virology"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1128\/JVI.80.5.2162-2169.2006","article-title":"Proteomics analysis of the tombusvirus replicase: Hsp70 molecular chaperone is associated with the replicase and enhances viral RNA replication.","volume":"80","author":"S Serva","year":"2006","journal-title":"J Virol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"6911","DOI":"10.1128\/JVI.00702-08","article-title":"Cdc34p Ubiquitin-Conjugating Enzyme Is a Component of the Tombusvirus Replicase Complex and Ubiquitinates p33 Replication Protein.","volume":"82","author":"Z Li","year":"2008","journal-title":"J Virol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.virol.2008.11.041","article-title":"Translation elongation factor 1A is a component of the tombusvirus replicase complex and affects the stability of the p33 replication co-factor.","volume":"385","author":"Z Li","year":"2009","journal-title":"Virology"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.chom.2008.02.005","article-title":"Tomato bushy stunt virus Co-Opts the RNA-Binding Function of a Host Metabolic Enzyme for Viral Genomic RNA Synthesis.","volume":"3","author":"RY Wang","year":"2008","journal-title":"Cell Host Microbe"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"19956","DOI":"10.1073\/pnas.0810851105","article-title":"In vitro assembly of the Tomato bushy stunt virus replicase requires the host Heat shock protein 70.","volume":"105","author":"J Pogany","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev.phyto.121407.093958","article-title":"Yeast as a model host to explore plant virus-host interactions.","volume":"46","author":"PD Nagy","year":"2008","journal-title":"Annu Rev Phytopathol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"3276","DOI":"10.1128\/JVI.02313-08","article-title":"A key role for heat shock protein 70 in the localization and insertion of tombusvirus replication proteins to intracellular membranes.","volume":"83","author":"RY Wang","year":"2009","journal-title":"J Virol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"7394","DOI":"10.1128\/JVI.02686-05","article-title":"Identification of essential host factors affecting tombusvirus RNA replication based on the yeast Tet promoters Hughes Collection.","volume":"80","author":"Y Jiang","year":"2006","journal-title":"J Virol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"7326","DOI":"10.1073\/pnas.0502604102","article-title":"Yeast genome-wide screen reveals dissimilar sets of host genes affecting replication of RNA viruses.","volume":"102","author":"T Panavas","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1038\/nbt855","article-title":"Isolation of drugs active against mammalian prions using a yeast-based screening assay.","volume":"21","author":"S Bach","year":"2003","journal-title":"Nat Biotechnol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"4894","DOI":"10.1128\/JVI.74.10.4894-4897.2000","article-title":"Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation.","volume":"74","author":"K Doh-Ura","year":"2000","journal-title":"J Virol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"9836","DOI":"10.1073\/pnas.161274798","article-title":"Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease.","volume":"98","author":"C Korth","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"10595","DOI":"10.1073\/pnas.0803671105","article-title":"A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.","volume":"105","author":"P Spilman","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"5967","DOI":"10.1128\/JVI.02737-07","article-title":"Authentic replication and recombination of Tomato bushy stunt virus RNA in a cell-free extract from yeast.","volume":"82","author":"J Pogany","year":"2008","journal-title":"J Virol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1021\/la803288s","article-title":"Kinetics membrane disruption due to drug interactions of chlorpromazine hydrochloride.","volume":"25","author":"MR Nussio","year":"2009","journal-title":"Langmuir"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1006\/viro.2000.0577","article-title":"Partial purification and characterization of Cucumber necrosis virus and Tomato bushy stunt virus RNA-dependent RNA polymerases: similarities and differences in template usage between tombusvirus and carmovirus RNA-dependent RNA polymerases.","volume":"276","author":"PD Nagy","year":"2000","journal-title":"Virology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1006\/viro.2002.1423","article-title":"Analysis of minimal promoter sequences for plus-strand synthesis by the Cucumber necrosis virus RNA-dependent RNA polymerase.","volume":"296","author":"T Panavas","year":"2002","journal-title":"Virology"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"6737","DOI":"10.1016\/j.bmc.2008.05.060","article-title":"Antiprion activity of functionalized 9-aminoacridines related to quinacrine.","volume":"16","author":"TH Nguyen","year":"2008","journal-title":"Bioorg Med Chem"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1471-4159.2007.05140.x","article-title":"Gene expression profile of quinacrine-cured prion-infected mouse neuronal cells.","volume":"105","author":"C Fasano","year":"2008","journal-title":"J Neurochem"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2165\/00023210-200620010-00002","article-title":"Prion diseases: current understanding of epidemiology and pathogenesis, and therapeutic advances.","volume":"20","author":"M Caramelli","year":"2006","journal-title":"CNS Drugs"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"3563","DOI":"10.1021\/jm034093h","article-title":"Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein.","volume":"46","author":"M Vogtherr","year":"2003","journal-title":"J Med Chem"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"471","DOI":"10.2174\/138920307782411400","article-title":"A role of the 9-aminoacridines and their conjugates in a life science.","volume":"8","author":"J Sebestik","year":"2007","journal-title":"Curr Protein Pept Sci"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1002\/cbic.200700602","article-title":"A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer&apos;s beta-amyloid fibril formation.","volume":"9","author":"GT Dolphin","year":"2008","journal-title":"Chembiochem"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/j.1529-8019.2007.00131.x","article-title":"New concepts in antimalarial use and mode of action in dermatology.","volume":"20","author":"S Kalia","year":"2007","journal-title":"Dermatol Ther"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1080\/15287390500360281","article-title":"Evaluation of the protective effects of quinacrine against Bacillus anthracis Ames.","volume":"69","author":"JE Comer","year":"2006","journal-title":"J Toxicol Environ Health A"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.1472-8206.2008.00613.x","article-title":"Enhanced therapeutic effects on the multi-drug resistant human leukemia cells in vitro and xenograft in mice using the stealthy liposomal vincristine plus quinacrine.","volume":"22","author":"GW Liang","year":"2008","journal-title":"Fundam Clin Pharmacol"},{"key":"ref45","article-title":"Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced mutagenicity.","author":"PN Karamanakos","year":"2008","journal-title":"Arch Toxicol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1099\/vir.0.006387-0","article-title":"Crimean-Congo hemorrhagic fever virus entry and replication is clathrin-, pH- and cholesterol-dependent.","volume":"90","author":"M Simon","year":"2009","journal-title":"J Gen Virol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.antiviral.2008.06.004","article-title":"A clathrin-dynamin-dependent endocytic pathway for the uptake of HIV-1 by direct T cell-T cell transmission.","volume":"80","author":"B Bosch","year":"2008","journal-title":"Antiviral Res"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"8112","DOI":"10.1128\/JVI.00837-08","article-title":"Mouse hepatitis virus type 2 enters cells through a clathrin-mediated endocytic pathway independent of Eps15.","volume":"82","author":"Y Pu","year":"2008","journal-title":"J Virol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1099\/vir.0.83357-0","article-title":"Functional entry of dengue virus into Aedes albopictus mosquito cells is dependent on clathrin-mediated endocytosis.","volume":"89","author":"EG Acosta","year":"2008","journal-title":"J Gen Virol"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"8722","DOI":"10.1128\/JVI.00253-07","article-title":"Clathrin-dependent entry of severe acute respiratory syndrome coronavirus into target cells expressing ACE2 with the cytoplasmic tail deleted.","volume":"81","author":"Y Inoue","year":"2007","journal-title":"J Virol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.virol.2005.05.006","article-title":"Role of clathrin-mediated endocytosis during vesicular stomatitis virus entry into host cells.","volume":"338","author":"X Sun","year":"2005","journal-title":"Virology"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1091\/mbc.E03-12-0921","article-title":"HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses.","volume":"15","author":"A Vendeville","year":"2004","journal-title":"Mol Biol Cell"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"8254","DOI":"10.1128\/JVI.78.15.8254-8263.2004","article-title":"Purification of the cucumber necrosis virus replicase from yeast cells: role of coexpressed viral RNA in stimulation of replicase activity.","volume":"78","author":"Z Panaviene","year":"2004","journal-title":"J Virol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"5889","DOI":"10.1016\/j.bmcl.2004.09.021","article-title":"Binding of an aminoacridine derivative to a GAAA RNA tetraloop.","volume":"14","author":"Z Yan","year":"2004","journal-title":"Bioorg Med Chem Lett"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S1074-5521(03)00147-9","article-title":"Preferred RNA binding sites for a threading intercalator revealed by in vitro evolution.","volume":"10","author":"CB Carlson","year":"2003","journal-title":"Chem Biol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1016\/j.bbagen.2007.08.018","article-title":"RNA targeting by DNA binding drugs: structural, conformational and energetic aspects of the binding of quinacrine and DAPI to A-form and H(L)-form of poly(rC).poly(rG).","volume":"1770","author":"R Sinha","year":"2007","journal-title":"Biochim Biophys Acta"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.abb.2008.03.013","article-title":"Self-structure induction in single stranded poly(A) by small molecules: Studies on DNA intercalators, partial intercalators and groove binding molecules.","volume":"474","author":"P Giri","year":"2008","journal-title":"Arch Biochem Biophys"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/978-1-59745-102-4_4","article-title":"Multiple roles of viral replication proteins in plant RNA virus replication.","volume":"451","author":"PD Nagy","year":"2008","journal-title":"Methods Mol Biol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1083\/jcb.136.5.995","article-title":"Inner but not outer membrane leaflets control the transition from glycosylphosphatidylinositol-anchored influenza hemagglutinin-induced hemifusion to full fusion.","volume":"136","author":"GB Melikyan","year":"1997","journal-title":"J Cell Biol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"3513","DOI":"10.1105\/tpc.105.036350","article-title":"Localization of the Tomato Bushy Stunt Virus Replication Protein p33 Reveals a Peroxisome-to-Endoplasmic Reticulum Sorting Pathway.","volume":"17","author":"AW McCartney","year":"2005","journal-title":"Plant Cell"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"e220","DOI":"10.1371\/journal.pbio.0050220","article-title":"Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelle.","volume":"5","author":"BG Kopek","year":"2007","journal-title":"PLoS Biol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"e2174","DOI":"10.1371\/journal.pone.0002174","article-title":"Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs.","volume":"3","author":"D Tribouillard-Tanvier","year":"2008","journal-title":"PLoS ONE"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1002\/biot.200800134","article-title":"Tools for the study of ribosome-borne protein folding activity.","volume":"3","author":"C Voisset","year":"2008","journal-title":"Biotechnol J"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"8181","DOI":"10.1128\/JVI.77.15.8181-8186.2003","article-title":"Host factors in positive-strand RNA virus genome replication.","volume":"77","author":"P Ahlquist","year":"2003","journal-title":"J Virol"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/BF01309305","article-title":"Verapamil inhibits influenza A virus replication.","volume":"81","author":"KM Nugent","year":"1984","journal-title":"Arch Virol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0042-6822(89)90421-2","article-title":"Verapamil and chlorpromazine inhibit the budding of Sindbis and vesicular stomatitis viruses from infected chicken embryo fibroblasts.","volume":"168","author":"MJ Schlesinger","year":"1989","journal-title":"Virology"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/viro.2002.1422","article-title":"Internal initiation by the cucumber necrosis virus RNA-dependent RNA polymerase is facilitated by promoter-like sequences.","volume":"296","author":"T Panavas","year":"2002","journal-title":"Virology"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1128\/JVI.68.1.14-24.1994","article-title":"Nonhomologous RNA recombination in tombusviruses: generation and evolution of defective interfering RNAs by stepwise deletions.","volume":"68","author":"KA White","year":"1994","journal-title":"J Virol"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"9244","DOI":"10.1128\/JVI.77.17.9244-9258.2003","article-title":"Characterization of the RNA-binding domains in the replicase proteins of tomato bushy stunt virus.","volume":"77","author":"KS Rajendran","year":"2003","journal-title":"J Virol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.virol.2005.09.017","article-title":"Yeast as a model host to dissect functions of viral and host factors in tombusvirus replication.","volume":"344","author":"PD Nagy","year":"2006","journal-title":"Virology"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0007376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,17]],"date-time":"2024-03-17T03:53:16Z","timestamp":1710647596000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0007376"}},"subtitle":[],"editor":[{"given":"Brett","family":"Lindenbach","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2009,10,13]]},"references-count":70,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2009,10,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0007376","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10,13]]}}}