{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:51:13Z","timestamp":1791129073964,"version":"4.1.0"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2010,2,18]],"date-time":"2010-02-18T00:00:00Z","timestamp":1266451200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0009281","type":"journal-article","created":{"date-parts":[[2010,2,17]],"date-time":"2010-02-17T23:10:06Z","timestamp":1266448206000},"page":"e9281","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":18,"title":["CD8+ DC, but Not CD8\u2212DC, Isolated from BCG-Infected Mice Reduces Pathological Reactions Induced by Mycobacterial Challenge Infection"],"prefix":"10.1371","volume":"5","author":[{"given":"Xiaoling","family":"Gao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhe","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijun","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2010,2,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1001\/jama.282.7.677","article-title":"Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project.","volume":"282","author":"C Dye","year":"1999","journal-title":"JAMA"},{"key":"ref2","article-title":"TB\/HIV: a clinical manual. 2nd ed. Geneva, Switzerland.","year":"2004","journal-title":"World Health Organization"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1136\/adc.2006.102889","article-title":"the epidemiology of tuberculosis in Europe.","volume":"92","author":"T Walls","year":"2007","journal-title":"Arch Dis Child"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1183\/09031936.05.00075704","article-title":"Drug resistance in tuberculosis.","volume":"25","author":"DA Mitchison","year":"2005","journal-title":"Eur Respir J"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1046\/j.0818-9641.2002.01143.x","article-title":"Improving vaccines against tuberculosis.","volume":"81","author":"WJ Britton","year":"2003","journal-title":"Immunol Cell Biol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/1521-4141(200206)32:6<1605::AID-IMMU1605>3.0.CO;2-6","article-title":"Active tuberculosis in Africa is associated with reduced Th1 and increased Th2 activity in vivo.","volume":"32","author":"C Lienhardt","year":"2002","journal-title":"Eur J Immunol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1146\/annurev.immunol.20.081501.125851","article-title":"Genetic dissection of immunity to mycobacteria: the human model.","volume":"20","author":"JL Casanova","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.micinf.2005.10.033","article-title":"Lessons from experimental Mycobacterium tuberculosis infections.","volume":"8","author":"JL Flynn","year":"2006","journal-title":"Microbes Infect"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.micinf.2005.03.008","article-title":"The use of animal models to guide rational vaccine design.","volume":"7","author":"IM Orme","year":"2005","journal-title":"Microbes Infect"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1146\/annurev.immunol.20.100301.064828","article-title":"Antigen presentation and T cell stimulation by dendritic cells.","volume":"20","author":"P Guermonprez","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1046\/j.1365-2567.2003.01609.x","article-title":"Dendritic cells recruited to the lung shortly after intranasal delivery of Mycobacterium bovis BCG drive the primary immune response towards a type 1 cytokine production.","volume":"108","author":"M Lagranderie","year":"2003","journal-title":"Immunology"},{"key":"ref12","first-page":"133","article-title":"Dendritic cells: key cells for the induction of regulatory T cells?","volume":"293","author":"K Mahnke","year":"2005","journal-title":"Curr Top Microbiol Immunol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1038\/nri1485","article-title":"Regulatory T cells: friend or foe in immunity to infection?","volume":"4","author":"KH Mills","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"4636","DOI":"10.4049\/jimmunol.168.9.4636","article-title":"Mycobacterium tuberculosis induces differential cytokine production from dendritic cells and macrophages with divergent effects on naive T cell polarization.","volume":"168","author":"SP Hickman","year":"2002","journal-title":"J Immunol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1365-2567.2007.02650.x","article-title":"Differential CD4(+) T-cell memory responses induced by two subsets of human monocyte-derived dendritic cells.","volume":"122","author":"S Bajana","year":"2007","journal-title":"Immunology"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1084\/jem.176.1.47","article-title":"The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.","volume":"176","author":"D Vremec","year":"1992","journal-title":"J Exp Med"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1073\/pnas.96.3.1036","article-title":"Distinct dendritic cell subsets differentially regulate the class of immune response in vivo.","volume":"96","author":"B Pulendran","year":"1999","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1084\/jem.189.3.587","article-title":"CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo.","volume":"189","author":"R Maldonado-Lopez","year":"1999","journal-title":"J Exp Med"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.coi.2007.10.009","article-title":"Division of labor, plasticity, and crosstalk between dendritic cell subsets.","volume":"20","author":"B Pulendran","year":"2008","journal-title":"Curr Opin Immunol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.4049\/jimmunol.171.5.2581","article-title":"Functional plasticity of dendritic cell subsets as mediated by CD40 versus B7 activation.","volume":"171","author":"U Grohmann","year":"2003","journal-title":"J Immunol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"7067","DOI":"10.4049\/jimmunol.177.10.7067","article-title":"Adoptive transfer of CD8alpha+ dendritic cells (DC) isolated from mice infected with Chlamydia muridarum are more potent in inducing protective immunity than CD8alpha- DC.","volume":"177","author":"L Bilenki","year":"2006","journal-title":"J Immunol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1164\/rccm.200804-517OC","article-title":"Natural killer T cells are critical for dendritic cells to induce immunity in Chlamydial pneumonia.","volume":"178","author":"AG Joyee","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1471-2172-5-3","article-title":"Rat pro-inflammatory cytokine and cytokine related mRNA quantification by real-time polymerase chain reaction using SYBR green.","volume":"5","author":"A Peinnequin","year":"2004","journal-title":"BMC Immunol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1002\/(SICI)1521-4141(199906)29:06<1972::AID-IMMU1972>3.0.CO;2-1","article-title":"Protection against aerosol Mycobacterium tuberculosis infection using Mycobacterium bovis Bacillus Calmette Guerin-infected dendritic cells.","volume":"29","author":"C Demangel","year":"1999","journal-title":"Eur J Immunol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0008-8749(03)00010-8","article-title":"Florid pulmonary inflammatory responses in mice vaccinated with Antigen-85 pulsed dendritic cells and challenged by aerosol with Mycobacterium tuberculosis.","volume":"220","author":"M Gonzalez-Juarrero","year":"2002","journal-title":"Cell Immunol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.4049\/jimmunol.160.5.2166","article-title":"Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover.","volume":"160","author":"PJ Leenen","year":"1998","journal-title":"J Immunol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.4049\/jimmunol.159.5.2222","article-title":"Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.","volume":"159","author":"B Pulendran","year":"1997","journal-title":"J Immunol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.4049\/jimmunol.168.3.1294","article-title":"Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity.","volume":"168","author":"X Jiao","year":"2002","journal-title":"J Immunol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1084\/jem.192.12.1685","article-title":"CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.","volume":"192","author":"JM den Haan","year":"2000","journal-title":"J Exp Med"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"6762","DOI":"10.4049\/jimmunol.165.12.6762","article-title":"The development, maturation, and turnover rate of mouse spleen dendritic cell populations.","volume":"165","author":"AT Kamath","year":"2000","journal-title":"J Immunol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"4345","DOI":"10.4049\/jimmunol.167.8.4345","article-title":"Cytokines regulate the capacity of CD8alpha(+) and CD8alpha(-) dendritic cells to prime Th1\/Th2 cells in vivo.","volume":"167","author":"R Maldonado-Lopez","year":"2001","journal-title":"J Immunol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1084\/jem.20052545","article-title":"Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection.","volume":"203","author":"SA Khader","year":"2006","journal-title":"J Exp Med"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"3890","DOI":"10.4049\/jimmunol.163.7.3890","article-title":"Dendritic cell (DC)-based anti-infective strategies: DCs engineered to secrete IL-12 are a potent vaccine in a murine model of an intracellular infection.","volume":"163","author":"SS Ahuja","year":"1999","journal-title":"J Immunol"},{"key":"ref34","first-page":"1332","article-title":"Biological functions of IFN-gamma and IFN-alpha\/beta: lessons from studies in gene knockout mice.","volume":"69","author":"R Kamijo","year":"1994","journal-title":"Hokkaido Igaku Zasshi"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0008-8749(91)90014-3","article-title":"Interferon-gamma-treated murine macrophages inhibit growth of tubercle bacilli via the generation of reactive nitrogen intermediates.","volume":"132","author":"M Denis","year":"1991","journal-title":"Cell Immunol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"10729","DOI":"10.1073\/pnas.0601956103","article-title":"The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture.","volume":"103","author":"P Schnorrer","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1126\/science.1136080","article-title":"Differential antigen processing by dendritic cell subsets in vivo.","volume":"315","author":"D Dudziak","year":"2007","journal-title":"Science"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1046\/j.1365-2249.1998.00636.x","article-title":"Mice incapable of making IL-4 or IL-10 display normal resistance to infection with Mycobacterium tuberculosis.","volume":"113","author":"RJ North","year":"1998","journal-title":"Clin Exp Immunol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"6343","DOI":"10.4049\/jimmunol.169.11.6343","article-title":"In vivo IL-10 production reactivates chronic pulmonary tuberculosis in C57BL\/6 mice.","volume":"169","author":"J Turner","year":"2002","journal-title":"J Immunol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0009281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T08:50:26Z","timestamp":1685436626000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0009281"}},"subtitle":[],"editor":[{"given":"Anil Kumar","family":"Tyagi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2010,2,18]]},"references-count":39,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2010,2,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0009281","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2,18]]}}}